Intergenerational implications of alcohol intake: metabolic disorders in alcohol-naïve rat offspring.

abstract：:Determining whether a population is introduced or native to a region can be challenging due to inadequate taxonomy, the presence of cryptic lineages, and poor historical documentation. For taxa with resting stages that bloom episodically, determining origin can be especially challenging as an environmentally-triggered...

journal_title：PeerJ

authors： Govindarajan AF,Carman MR,Khaidarov MR,Semenchenko A,Wares JP

更新日期：2017-04-18 00:00:00

abstract：:The expansion of the wind energy industry has had benefits in terms of increased renewable energy production but has also led to increased mortality of migratory bats due to interactions with wind turbines. A key question that could guide bat-related management activities is identifying the geographic origin of bats k...

journal_title：PeerJ

authors： Wieringa JG,Nagel J,Nelson DM,Carstens BC,Gibbs HL

更新日期：2020-10-19 00:00:00

abstract：:Combination Index (CI) analysis suggested that MBIC and doxorubicin synergistically inhibited up to 97% of cell proliferation in ER+/PR+MCF-7 and triple negative MDA-MB-231 breast cancer cell lines. Moreover, treatment of the breast cancer cells with the combined drugs resulted in lower IC50 values in contrast to the ...

journal_title：PeerJ

authors： Hasanpourghadi M,Abdul Majid N,Rais Mustafa M

更新日期：2018-09-17 00:00:00

abstract：:The decline in the number of hours Americans spend outdoors, exacerbated by urbanization, has affected people's familiarity with local wildlife. This is concerning to conservationists, as people tend to care about and invest in what they know. Children represent the future supporters of conservation, such that their k...

journal_title：PeerJ

authors： Schuttler SG,Stevenson K,Kays R,Dunn RR

更新日期：2019-07-23 00:00:00

abstract：:Mass spectrometry-based proteomics facilitate disease understanding by providing protein abundance information about disease progression. For the same type of disease studies, multiple mass spectrometry datasets may be generated. Integrating multiple mass spectrometry datasets can provide valuable information that a s...

journal_title：PeerJ

authors： Ryu SY,Wendt GA

更新日期：2019-04-10 00:00:00

abstract：:Protoporphyrin (PP) and biliverdin (BV) give rise to the enormous diversity in avian egg coloration. Egg color serves several ecological purposes, including post-mating signaling and camouflage. Egg camouflage represents a major character of open-nesting birds which accomplish protection of their unhatched offspring a...

journal_title：PeerJ

authors： Wiemann J,Yang TR,Sander PN,Schneider M,Engeser M,Kath-Schorr S,Müller CE,Sander PM

更新日期：2017-08-29 00:00:00

abstract：:Diarrhea is a syndrome of digestive disorders in young rabbits and may lead to secondary infections resulting in reduced immunity and higher mortality in baby rabbits, with serious impacts on rabbit farming. In this study, we investigated the effects of diarrhea on the health of baby rabbits in terms of intestinal muc...

journal_title：PeerJ

authors： Chen Y,Zhao B,Wu Y,Hu S,Mu L,Zhu C,Pan Y,Wu X

更新日期：2017-11-27 00:00:00

abstract：:A new species of freshwater crab, Fredius ibiapaba, is described and illustrated from a mid-altitude forested patch in Ipú (Ibiapaba plateau, Ceará, northeastern Brazil), between 635 to 782 m. The new species can be separated from its congeners by the morphology of its first gonopod: proximal half remarkably swollen, ...

journal_title：PeerJ

authors： Santos LC,Tavares M,Silva JRF,Cervini M,Pinheiro AP,Santana W

更新日期：2020-06-29 00:00:00

abstract：BACKGROUND:Zika virus (ZIKV) transmission has been reported in 67 countries/territories in the Oceania region and the Americas since 2015, prompting the World Health Organization (WHO) to declare ZIKV as a Public Health Emergency of International Concern in February 2016, due to its strong association with medical comp...

journal_title：PeerJ

authors： Hsieh YH

更新日期：2017-03-21 00:00:00

abstract：Background:Variation in management across elephant camps likely has differential effects on the well-being of elephants. Methods:This study calculated body condition, foot health and skin wound scores (WSs) for 122 elephants from 15 elephant camps in Chiang Mai province, and examined relationships to management factor...

journal_title：PeerJ

authors： Bansiddhi P,Nganvongpanit K,Brown JL,Punyapornwithaya V,Pongsopawijit P,Thitaram C

更新日期：2019-04-25 00:00:00

abstract：:Natural products from the unique environments of sea water and oceans represent a largely unfamiliar source for isolation of new microbes, which are potent producers of secondary bioactive metabolites. These unique life-forms from the marine ecosphere have served as an important source of drugs since ancient times and...

journal_title：PeerJ

authors： Adnan M,Alshammari E,Patel M,Amir Ashraf S,Khan S,Hadi S

更新日期：2018-06-27 00:00:00

abstract：:Deposits spanning the Radotruncana calcarata Taxon Range Zone at the Postalm section, Northern Calcareous Alps (Austria) are examined quantitatively for foraminiferal assemblages, especially the planktonic group. This study focuses on establishing a high resolution record spanning an 800 ka long stratigraphic interval...

journal_title：PeerJ

authors： Wolfgring E,Wagreich M

更新日期：2016-03-08 00:00:00

abstract：Background and Aims:The link between gut microbiota and type 2 diabetes (T2D) has been addressed by numerous studies. Streptococcus thermophilus from fermented milk products, has been used as a probiotic in previous research. However, whether heat-killed S. thermophilus can improve the glycemic parameters of diabetic r...

journal_title：PeerJ

authors： Gao X,Wang F,Zhao P,Zhang R,Zeng Q

更新日期：2019-06-13 00:00:00

abstract：:Synechococcus is among the most important contributors to global primary productivity. The genomes of several strains of this taxon have been previously sequenced in an effort to understand the physiology and ecology of these highly diverse microorganisms. Here we present a comparative study of Synechococcus genomes. ...

journal_title：PeerJ

authors： Coutinho F,Tschoeke DA,Thompson F,Thompson C

更新日期：2016-01-14 00:00:00

abstract：:Although neonicotinoids are targeted at insects, their predominant use as a seed dressing and their long persistence in soils mean that non-target soil organisms such as earthworms are likely to be chronically exposed to them. Chronic exposure may pose risks that are not evaluated in most toxicity tests. We experiment...

journal_title：PeerJ

authors： Basley K,Goulson D

更新日期：2017-04-11 00:00:00

abstract：:Elucidating the molecular mechanism of helix-coil transitions of short peptides is a long-standing conundrum in physical chemistry. Although the helix-coil transitions of poly-glutamic acid (PGA) have been extensively studied, the molecular details of its unfolding process still remain unclear. We performed all-atom c...

journal_title：PeerJ

authors： Ogasawara N,Kasahara K,Iwai R,Takahashi T

更新日期：2018-05-15 00:00:00

abstract：:RNA sequencing (RNA-Seq) enables the measurement and comparison of gene expression with isoform-level quantification. Differences in the effect of each isoform may make traditional methods, which aggregate isoforms, ineffective. Here, we introduce a variance component-based test that can jointly test multiple isoforms...

journal_title：PeerJ

authors： Yang S,Shao F,Duan W,Zhao Y,Chen F

更新日期：2017-09-08 00:00:00

abstract：:In most electric fish species, the electric organ (EO) derives from striated muscle cells that suppress many muscle properties. In the gymnotiform Sternopygus macrurus, mature electrocytes, the current-producing cells of the EO, do not contain sarcomeres, yet they continue to make some cytoskeletal and sarcomeric prot...

journal_title：PeerJ

authors： Pinch M,Güth R,Samanta MP,Chaidez A,Unguez GA

更新日期：2016-04-14 00:00:00

abstract：BACKGROUND:Rare or narrowly endemic organisms are difficult to monitor and conserve when their total distribution and habitat preferences are incompletely known. One method employed in determining distributions of these organisms is species distribution modeling (SDM). METHODS:Using two species of narrowly endemic bur...

journal_title：PeerJ

authors： Rhoden CM,Peterman WE,Taylor CA

更新日期：2017-07-31 00:00:00

abstract：:MicoRNAs (miRNAs), usually as gene regulators, participate in various biological processes, including stress responses. The hypothalamus-pituitary-adrenal axis (HPA axis) is an important pathway in regulating stress response. Although the mechanism that HPA axis regulates stress response has been basically revealed, t...

journal_title：PeerJ

authors： Luo W,Fang M,Xu H,Xing H,Fu J,Nie Q

更新日期：2016-02-18 00:00:00

abstract：:Genome sequencing is rapidly being adopted in reference labs and hospitals for bacterial outbreak investigation and diagnostics where time is critical. Seven gene multi-locus sequence typing is a standard tool for broadly classifying samples into sequence types (STs), allowing, in many cases, to rule a sample out of a...

journal_title：PeerJ

authors： Page AJ,Keane JA

更新日期：2018-07-31 00:00:00

abstract：:Bovine odorant-binding protein (bOBP) differs from other lipocalins by lacking the conserved disulfide bond and for being able to form the domain-swapped dimers. To identify structural features responsible for the formation of the bOBP unique dimeric structure and to understand the role of the domain swapping on maint...

journal_title：PeerJ

authors： Stepanenko OV,Roginskii DO,Stepanenko OV,Kuznetsova IM,Uversky VN,Turoverov KK

更新日期：2016-04-18 00:00:00

abstract：:Harmine is the β-carboline alkaloid with the highest concentration in the psychotropic plant decoction Ayahuasca. In rodents, classical antidepressants reverse the symptoms of depression by stimulating neuronal proliferation. It has been shown that Ayahuasca presents antidepressant effects in patients with depressive ...

journal_title：PeerJ

authors： Dakic V,Maciel RM,Drummond H,Nascimento JM,Trindade P,Rehen SK

更新日期：2016-12-06 00:00:00

abstract：BACKGROUND:The composition of the salivary microbiota has been reported to differentiate between patients with periodontitis, dental caries and orally healthy individuals. To identify characteristics of diseased and healthy saliva we thus wanted to compare saliva metaproteomes from patients with periodontitis and denta...

journal_title：PeerJ

authors： Belstrøm D,Jersie-Christensen RR,Lyon D,Damgaard C,Jensen LJ,Holmstrup P,Olsen JV

更新日期：2016-09-14 00:00:00

abstract：:The mitochondrial genome (mitogenome) sequence of the tree frog Polypedates megacephalus (16,473 bp) was previously reported as having the unusual characteristic of lacking the ND5 gene. In this study, a new mitogenome of P. megacephalus (19,952 bp) was resequenced using the next-generation sequencing (NGS) and standa...

journal_title：PeerJ

authors： Huang A,Liu S,Li H,Luo H,Ni Q,Yao Y,Xu H,Zeng B,Li Y,Wei Z,Li S,Zhang M

更新日期：2019-08-01 00:00:00

abstract：:Recent improvements in next-generation sequencing (NGS) technologies can facilitate the obtainment of mitochondrial genomes. However, it is not clear whether NGS could be effectively used to reconstruct the mitogenome with high gene rearrangement. These high rearrangements would cause amplification failure, and/or ass...

journal_title：PeerJ

authors： Yuan S,Xia Y,Zheng Y,Zeng X

更新日期：2016-12-15 00:00:00

abstract：Background:Begomoviruses are widely distributed and causing devastating diseases in many crops. According to the number of genomic components, a begomovirus is known as either monopartite or bipartite begomovirus. Both the monopartite and bipartite begomoviruses have the DNA-A component which encodes all essential prot...

journal_title：PeerJ

authors： Pei S,Dong R,Bao Y,He RL,Yau SS

更新日期：2020-08-03 00:00:00

abstract：Background:Efficient communication requires that signals are well transmitted and perceived in a given environment. Natural selection therefore drives the evolution of different signals in different environments. In addition, environmental heterogeneity at small spatial or temporal scales may favour phenotypic plastici...

journal_title：PeerJ

authors： Wright DS,Rietveld E,Maan ME

更新日期：2018-01-03 00:00:00

abstract：:Wild edible mushrooms have been collected and consumed by human groups for centuries, and today they represent a relevant source of food and income for many rural families worldwide. Preserving these non-timber forest products is of great interest, and there is concern about the damage caused by intensive mushroom har...

journal_title：PeerJ

authors： Ruiz-Almenara C,Gándara E,Gómez-Hernández M

更新日期：2019-12-18 00:00:00

abstract：:Myocardial infarction has been carefully studied in numerous experimental models. Most of these models are based on electrophysiological and functional data, and pay less attention to histological discoveries. During the last decade, treatment using advanced therapies, mainly cell therapy, has prevailed from among all...

journal_title：PeerJ

authors： García Gómez-Heras S,Largo C,Larrea JL,Vega-Clemente L,Calderón Flores M,Ruiz-Pérez D,García-Olmo D,García-Arranz M

更新日期：2019-07-22 00:00:00