The influence of scopolamine on motor control and attentional processes.

abstract：AIM:To prospectively evaluate the effects of vitamin D3 on disease activity and quality of life in ulcerative colitis (UC) patients with hypovitaminosis D. METHODS:The study was a prospective double-blinded, randomized trial conducted at Community Regional Medical Center, Fresno, CA from 2012-2013. Patients with UC an...

journal_title：PeerJ

authors： Mathur J,Naing S,Mills P,Limsui D

更新日期：2017-08-03 00:00:00

abstract：:N6-methyladenosine (m6A) modifications can be found in eukaryotic messenger RNA (mRNA), long non-coding RNA (lncRNA), and microRNA (miRNA). Several studies have demonstrated a close relationship between m6A modifications and cancer cells. Methyltransferase-like enzyme 3 (METTL3) and methyltransferase-like enzyme 14 (M...

journal_title：PeerJ

authors： Tao Z,Zhao Y,Chen X

更新日期：2020-07-22 00:00:00

abstract：:N-Acetyl-p-Aminophenol (APAP), also known as acetaminophen, is the most commonly used over-the counter analgesic and antipyretic medication. However, its overdose leads to both liver and kidney damage. APAP-induced toxicity is considered as one of the primary causes of acute liver failure; numerous scientific reports ...

journal_title：PeerJ

authors： Karthivashan G,Kura AU,Arulselvan P,Md Isa N,Fakurazi S

更新日期：2016-07-07 00:00:00

abstract：:Wing pigmentation in Calopteryx damselflies, caused by the deposition of melanin, is energetically expensive to produce and enhances predation risk. However, patterns of melanisation are used in species identification, greater pigmentation is an accurate signal of male immune function in at least some species, and the...

journal_title：PeerJ

authors： Hassall C

更新日期：2014-06-10 00:00:00

abstract：:Cordycepin is a component of the extract obtained from Cordyceps militaris and has many biological activities, including anti-cancer, anti-metastatic and anti-inflammatory effects. Intervertebral disc degeneration (IDD) is a degenerative disease that is closely related to the inflammation of nucleus pulposus (NP) cell...

journal_title：PeerJ

authors： Li Y,Li K,Mao L,Han X,Zhang K,Zhao C,Zhao J

更新日期：2016-05-10 00:00:00

abstract：:The fight against the emergence of mutant influenza strains has led to the screening of an increasing number of compounds for inhibitory activity against influenza neuraminidase. This study explores the chemical space of neuraminidase inhibitors (NAIs), which provides an opportunity to obtain further molecular insight...

journal_title：PeerJ

authors： Anuwongcharoen N,Shoombuatong W,Tantimongcolwat T,Prachayasittikul V,Nantasenamat C

更新日期：2016-04-19 00:00:00

abstract：:The proportion of females calving (PFC) each year has been employed as an indicator of population reproductive performance in ungulates, especially for species that breed annually, because it requires less detailed population data than inter-birthing intervals and age at first reproduction. For asynchronous breeders w...

journal_title：PeerJ

authors： Law PR,Fike B

更新日期：2018-08-15 00:00:00

abstract：INTRODUCTION:The aim of this study was to determine the incidence rates of endometrial hyperplasia (EH) and endometrial cancer (EC) in the Republic of Korea using national insurance claim data generated from 2009 to 2012. MATERIALS AND METHODS:Data that were generated from 2009 to 2012 were sourced from the Korean Hea...

journal_title：PeerJ

authors： Yuk JS

更新日期：2016-08-24 00:00:00

abstract：:The evolution of the modern human (Homo sapiens) cranium is characterized by a reduction in the size of the feeding system, including reductions in the size of the facial skeleton, postcanine teeth, and the muscles involved in biting and chewing. The conventional view hypothesizes that gracilization of the human feedi...

journal_title：PeerJ

authors： Ledogar JA,Dechow PC,Wang Q,Gharpure PH,Gordon AD,Baab KL,Smith AL,Weber GW,Grosse IR,Ross CF,Richmond BG,Wright BW,Byron C,Wroe S,Strait DS

更新日期：2016-07-26 00:00:00

abstract：:Alcohol drinking may be associated with an increased risk of various metabolic diseases. Rat lines selectively bred for alcohol preference and alcohol avoidance constitute an interesting model to study inherited factors related to alcohol drinking and metabolic disorders. The aim of the present study was to compare th...

journal_title：PeerJ

authors： Mierzejewski P,Zakrzewska A,Kuczyńska J,Wyszogrodzka E,Dominiak M

更新日期：2020-09-11 00:00:00

abstract：:Diffuse sources of pollution like agricultural or urban runoff are important factors in determining the quality of surface waters, although they are more difficult to monitor than point sources. The objective of our study was to verify assumptions that the inflow from agricultural nutrient sources is higher than from ...

journal_title：PeerJ

authors： Matej-Lukowicz K,Wojciechowska E,Nawrot N,Dzierzbicka-Głowacka LA

更新日期：2020-02-06 00:00:00

abstract：:In group-living animals, heterogeneity in individuals' social connections may mediate the sharing of microbial infectious agents. In this regard, the genetic relatedness of individuals' commensal gut bacterium Escherichia coli may be ideal to assess the potential for pathogen transmission through animal social network...

journal_title：PeerJ

authors： Balasubramaniam K,Beisner B,Guan J,Vandeleest J,Fushing H,Atwill E,McCowan B

更新日期：2018-01-17 00:00:00

abstract：:Loud calls are used by many species as long-distance signals for group defense, mate attraction, and inter- and intragroup spacing. Chimpanzee loud calls, or pant hoots, are used in a variety of contexts including group coordination and during male contests. Here, we observed an alpha male takeover in wild chimpanzees...

journal_title：PeerJ

authors： Kalan AK,Boesch C

更新日期：2018-06-28 00:00:00

abstract：Background:Oral squamous cell carcinoma (OSCC) is a major lethal malignant cancer of the head and neck region, yet its molecular mechanisms of tumourigenesis are still unclear. Patients and methods:We performed weighted gene co-expression network analysis (WGCNA) on RNA-sequencing data with clinical information obtain...

journal_title：PeerJ

authors： Hu X,Sun G,Shi Z,Ni H,Jiang S

更新日期：2020-02-04 00:00:00

abstract：Purpose:To explore whether unilateral relapse of Bechet's disease-associated uveitis (BDU) causes differences in the tear proteome between the diseased and the contralateral quiescent eye and potential tear biomarkers for uveitis recurrence and disease monitoring. Method:To minimize interindividual variations, bilater...

journal_title：PeerJ

authors： Liang A,Qin W,Zhang M,Gao F,Zhao C,Gao Y

更新日期：2020-06-19 00:00:00

abstract：:Because microorganisms are sensitive to temperature, ongoing global warming is predicted to influence microbial community structure and function. We used large-scale warming experiments established at two sites near the northern and southern boundaries of US eastern deciduous forests to explore how microbial communiti...

journal_title：PeerJ

authors： Cregger MA,Sanders NJ,Dunn RR,Classen AT

更新日期：2014-04-24 00:00:00

abstract：:Twist1, a basic helix-loop-helix transcription factor that regulates a number of genes involved in epithelial-to-mesenchymal transition (EMT), is upregulated in prostate cancer. Androgen regulation of Twist1 has been reported in a previous study. However, the mechanism of androgen regulation of the Twist1 gene is not ...

journal_title：PeerJ

authors： Khatiwada P,Kannan A,Malla M,Dreier M,Shemshedini L

更新日期：2020-04-09 00:00:00

abstract：:The blacklegged tick Ixodes scapularis is widely distributed in the United States and transmits multiple pathogens to humans, wildlife and domestic animals. Recently, several novel viruses in the family Bunyaviridae (South Bay virus (SBV) and Blacklegged tick phlebovirus (BTPV)) were identified infecting female I. sca...

journal_title：PeerJ

authors： Sakamoto JM,Ng TFF,Suzuki Y,Tsujimoto H,Deng X,Delwart E,Rasgon JL

更新日期：2016-08-11 00:00:00

abstract：Background:Humpback whales (Megaptera novaeangliae) are a widespread, vocal baleen whale best known for producing song, a complex, repetitive, geographically distinct acoustic signal sung by males, predominantly in a breeding context. Humpback whales worldwide also produce non-song vocalizations ("calls") throughout th...

journal_title：PeerJ

authors： Fournet MEH,Jacobsen L,Gabriele CM,Mellinger DK,Klinck H

更新日期：2018-07-30 00:00:00

abstract：:Female adders (Vipera berus) are "capital breeders" that exhibit delayed maturity and intermittent reproductive frequency. We studied the attainment of sexual maturity, the initiation of annual breeding in mature females, the energy and mortality costs associated with breeding, the length of the reproductive cycle and...

journal_title：PeerJ

authors： Bauwens D,Claus K

更新日期：2019-05-09 00:00:00

abstract：:Parrotfish are fundamental species in controlling algal phase-shifts and ensuring the resilience of coral reefs. Nevertheless, little is known on their ecological role in the south-western Atlantic Ocean. The present study analysed the ontogenetic foraging activity and feeding selectivity of the Brazilian endemic parr...

journal_title：PeerJ

authors： Pereira PH,Santos M,Lippi DL,Silva P

更新日期：2016-10-12 00:00:00

abstract：:Dilated cardiomyopathy is a prevalent and often fatal disease in humans and dogs. Indeed dilated cardiomyopathy is the third most common form of cardiac disease in humans, reported to affect approximately 36 individuals per 100,000 individuals. In dogs, dilated cardiomyopathy is the second most common cardiac disease ...

journal_title：PeerJ

authors： Simpson S,Edwards J,Emes RD,Cobb MA,Mongan NP,Rutland CS

更新日期：2015-03-26 00:00:00

abstract：:This article is a presentation of taxonomic diversity of the orchid genus Cyrtochilum in Northwestern South America. The morphological characteristics of over 90 species occurring in northern Peru, Ecuador, Colombia and Venezuela are presented together with illustrations of their floral segments. Information about the...

journal_title：PeerJ

authors： Szlachetko DL,Kolanowska M

更新日期：2020-02-14 00:00:00

abstract：:The expansion of the wind energy industry has had benefits in terms of increased renewable energy production but has also led to increased mortality of migratory bats due to interactions with wind turbines. A key question that could guide bat-related management activities is identifying the geographic origin of bats k...

journal_title：PeerJ

authors： Wieringa JG,Nagel J,Nelson DM,Carstens BC,Gibbs HL

更新日期：2020-10-19 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most heterogeneous malignant cancers with no effective targets and treatments. However, the molecular pathogenesis of HCC remains largely uncertain. The aims of our study were to find crucial genes involved in HCC through multidimensional methods and revealed potential mole...

journal_title：PeerJ

authors： Liu ZK,Zhang RY,Yong YL,Zhang ZY,Li C,Chen ZN,Bian H

更新日期：2019-08-08 00:00:00

abstract：:Jatropha curcas L. belongs to Euphorbiaceae family, and it synthesizes flavonoid and diterpene compounds that have showed antioxidant, anti-inflammatory, anticancer, antiviral, antimicrobial, antifungal and insecticide activity. Seeds of this plant accumulate phorbol esters, which are tigliane type diterpenes, reporte...

journal_title：PeerJ

authors： Leyva-Padrón G,Vanegas-Espinoza PE,Evangelista-Lozano S,Del Villar-Martínez AA,Bazaldúa C

更新日期：2020-11-11 00:00:00

abstract：:Mauremys reevesii is a classical organism with temperature-dependent sex determination (TSD). Gonad development in early life has recently received considerable attention but gonadal maintenance after sex differentiation in turtles with TSD remains a mystery. In this study, we sequenced the transcriptomes for the adul...

journal_title：PeerJ

authors： Xiong L,Dong J,Jiang H,Zan J,Tong J,Liu J,Wang M,Nie L

更新日期：2019-03-08 00:00:00

abstract：:Wolbachia is an alpha-proteobacterial symbiont widely distributed in arthropods. Since the identification of Wolbachia in certain animal-parasitic nematodes (the Onchocercidae or filariae), the relationship between arthropod and nematode Wolbachia has attracted great interest. The obligate symbiosis in filariae, which...

journal_title：PeerJ

authors： Lefoulon E,Bain O,Makepeace BL,d'Haese C,Uni S,Martin C,Gavotte L

更新日期：2016-03-28 00:00:00

abstract：:This article aimed to give the visibility of Latin American researchers' contributions to the comprehension of COVID-19; our method was a literature review. Currently, the world is facing a health and socioeconomic crisis caused by the novel coronavirus, SARS-CoV-2, and its disease COVID-19. Therefore, in less than 4 ...

journal_title：PeerJ

authors： Fiesco-Sepúlveda KY,Serrano-Bermúdez LM

更新日期：2020-06-04 00:00:00

abstract：:The eukaryotic polypyrimidine tract binding protein (PTB) serves primarily as a regulator of alternative splicing of messenger RNA, but is also co-opted to other roles such as RNA localisation and translation initiation from internal ribosome entry sites. The neuronal paralogue of PTB (nPTB) is 75% identical in amino ...

journal_title：PeerJ

authors： Joshi A,Esteve V,Buckroyd AN,Blatter M,Allain FH,Curry S

更新日期：2014-03-13 00:00:00