Role of methyltransferase-like enzyme 3 and methyltransferase-like enzyme 14 in urological cancers.

abstract：:Movement is one of the most important epigenetic factors for normal development of the musculoskeletal system, particularly during genesis and joint development. Studies regarding alterations to embryonic mobility, performed on anurans, chickens and mammals, report important phenotypical similarities as a result of th...

journal_title：PeerJ

authors： Ponssa ML,Abdala V

更新日期：2016-02-18 00:00:00

abstract：:Here we provide evidence to support an extension of the recognized distributional range of the Mountain Elaenia (Elaenia frantzii) to include southern Mexico. We collected two specimens in breeding condition in northwestern Sierra Norte de Chiapas, Mexico. Morphologic and genetic evidence support their identity as Ela...

journal_title：PeerJ

authors： Hanna ZR,Ortiz-Ramírez MF,Ríos-Muñoz CA,Cayetano-Rosas H,Bowie RC,Navarro-Sigüenza AG

更新日期：2016-02-01 00:00:00

abstract：:The evolutionarily conserved Mediator complex is a critical player in regulating transcription. Comprised of approximately two dozen proteins, the Mediator integrates diverse regulatory signals through direct protein-protein interactions that, in turn, modulate the influence of Mediator on RNA Polymerase II activity. ...

journal_title：PeerJ

authors： Kostrouchová M,Kostrouch D,Chughtai AA,Kaššák F,Novotný JP,Kostrouchová V,Benda A,Krause MW,Saudek V,Kostrouchová M,Kostrouch Z

更新日期：2017-06-06 00:00:00

abstract：Purpose:Most studies on neuroblastoma (NB) have been conducted in Western countries or Japan. The objective of our study was to analyze clinical and pathological features, MYCN status, surgical methods, and prognosis in Chinese NB patients. Methods:A retrospective, single-center case series study of 275 NBs was implem...

journal_title：PeerJ

authors： Ma Y,Zheng J,Feng J,Chen L,Dong K,Xiao X

更新日期：2018-09-17 00:00:00

abstract：Background:Efficient communication requires that signals are well transmitted and perceived in a given environment. Natural selection therefore drives the evolution of different signals in different environments. In addition, environmental heterogeneity at small spatial or temporal scales may favour phenotypic plastici...

journal_title：PeerJ

authors： Wright DS,Rietveld E,Maan ME

更新日期：2018-01-03 00:00:00

abstract：:Background. Massively parallel sequencing technology is being used to sequence highly diverse populations of DNA such as that derived from heterogeneous cell mixtures containing both wild-type and disease-related states. At the core of such molecule tagging techniques is the tagging and identification of sequence read...

journal_title：PeerJ

authors： Andrews TD,Jeelall Y,Talaulikar D,Goodnow CC,Field MA

更新日期：2016-05-24 00:00:00

abstract：:In this study, we demonstrated the successful transformation of two pea (Pisum sativum L.) cultivars using Agrobacterium rhizogenes, whereby transgenic roots in the resulting composite plants showed expression of the gene encoding the green fluorescent protein. Subsequent to infection with A. rhizogenes, approximately...

journal_title：PeerJ

authors： Leppyanen IV,Kirienko AN,Dolgikh EA

更新日期：2019-03-06 00:00:00

abstract：:Natural and anthropogenic changes (e.g., land use change, pollution) will alter many environmental factors in the coming years, including the amount of solar radiation reaching the earth's surface. Alterations in solar radiation exposure is likely to impact the ecologies of many living organisms, including invertebrat...

journal_title：PeerJ

authors： Villena OC,Momen B,Sullivan J,Leisnham PT

更新日期：2018-12-18 00:00:00

abstract：:The ε subunit from ATP synthases acts as an ATP sensor in the bacterial cell to prevent ATP hydrolysis and thus the waste of ATP under conditions of low ATP concentration. However, the ATP binding affinities from various bacterial organisms differ markedly, over several orders of magnitude. For example, the ATP syntha...

journal_title：PeerJ

authors： Krah A,Bond PJ

更新日期：2018-09-05 00:00:00

abstract：Background:Foam cells (FCs) play crucial roles in the process of all stages of atherosclerosis. Smooth muscle cells (SMCs) and macrophages are the major sources of FCs. This study aimed to identify the common molecular mechanism in these two types of FCs. Methods:GSE28829, GSE43292, GSE68021, and GSE54666 were include...

journal_title：PeerJ

authors： Zhang K,Qin X,Zhou X,Zhou J,Wen P,Chen S,Wu M,Wu Y,Zhuang J

更新日期：2020-11-17 00:00:00

abstract：:A conglomerate bed from the Tournaisian Ballagan Formation of Scotland preserves a rich array of vertebrate and other nonmarine fossils providing an insight into the wider ecosystem and paleoenvironment that existed during this pivotal stage of Earth history. It challenges hypotheses of a long-lasting post-extinction ...

journal_title：PeerJ

authors： Clack JA,Bennett CE,Davies SJ,Scott AC,Sherwin JE,Smithson TR

更新日期：2019-01-03 00:00:00

abstract：BACKGROUND:Invasive species are among the most significant threats to biodiversity. The diet of invasive animal populations is a crucial factor that must be considered in the context of biological invasions. A broad dietary spectrum is a frequently cited characteristic of invasive species, allowing them to thrive in a ...

journal_title：PeerJ

authors： Courant J,Vogt S,Marques R,Measey J,Secondi J,Rebelo R,De Villiers A,Ihlow F,De Busschere C,Backeljau T,Rödder D,Herrel A

更新日期：2017-05-16 00:00:00

abstract：:Chloroplasts are typically inherited from the female parent and are haploid in most angiosperms, but rare intra-individual heteroplasmy in plastid genomes has been reported in plants. Here, we report an example of plastome heteroplasmy and its characteristics in Gentiana tongolensis (Gentianaceae). The plastid genome ...

journal_title：PeerJ

authors： Sun SS,Zhou XJ,Li ZZ,Song HY,Long ZC,Fu PC

更新日期：2019-11-27 00:00:00

abstract：BACKGROUND:Motion sickness may be caused by a sensory conflict between the visual and the vestibular systems. Scopolamine, known to be the most effective therapy to control the vegetative symptoms of motion sickness, acts on the vestibular nucleus and potentially the vestibulospinal pathway, which may affect balance an...

journal_title：PeerJ

authors： Bestaven E,Kambrun C,Guehl D,Cazalets JR,Guillaud E

更新日期：2016-05-05 00:00:00

abstract：Background:Converging evidence comparing barefoot (BF) and shod (SH) running highlights differences in foot-strike patterns and somatosensory feedback, among others. Anecdotal evidence from SH runners attempting BF running suggests a greater attentional demand may be experienced during BF running. However, little work ...

journal_title：PeerJ

authors： Snow NJ,Blair JFL,MacDonald GZ,Byrne JM,Basset FA

更新日期：2018-04-09 00:00:00

abstract：:A new species of the genus Mesacanthion Filipjev, 1927 was discovered during a survey of natural beaches of Jeju Island in South Korea. The new species Mesacanthion jejuensissp. nov. shares general morphology of the genus such as the outer labial and cephalic setae being situated at the middle of cephalic capsule, wel...

journal_title：PeerJ

authors： Jeong R,Tchesunov AV,Lee W

更新日期：2019-11-18 00:00:00

abstract：:Dinocephalian therapsids are renowned for their massive, pachyostotic and ornamented skulls adapted for head-to-head fighting during intraspecific combat. Synchrotron scanning of the tapinocephalid Moschops capensis reveals, for the first time, numerous anatomical adaptations of the central nervous system related to t...

journal_title：PeerJ

authors： Benoit J,Manger PR,Norton L,Fernandez V,Rubidge BS

更新日期：2017-08-10 00:00:00

abstract：:Almost all extant testudinids are highly associated with terrestrial habitats and the few tortoises with high affinity to aquatic environments are found within the genus Manouria. Manouria belongs to a clade which forms a sister taxon to all remaining tortoises and is suitable as a model for studying evolutionary tran...

journal_title：PeerJ

authors： Natchev N,Tzankov N,Werneburg I,Heiss E

更新日期：2015-08-11 00:00:00

abstract：:In this study, we propose and test a novel ensemble method for improving the accuracy of each method in flood susceptibility mapping using evidential belief function (EBF) and support vector machine (SVM). The outcome of the proposed method was compared with the results of each method. The proposed method was implemen...

journal_title：PeerJ

authors： Shafapour Tehrany M,Kumar L,Shabani F

更新日期：2019-10-09 00:00:00

abstract：:In a number of recent studies we used computer modeling to investigate the evolution of muscle leverage (moment arms) and function in extant and extinct archosaur lineages (crocodilians, dinosaurs including birds and pterosaurs). These studies sought to quantify the level of disparity and convergence in muscle moment ...

journal_title：PeerJ

authors： Bates K,Maidment SC,Schachner ER,Barrett PM

更新日期：2015-10-08 00:00:00

abstract：BACKGROUND:Information on cardiovascular gene transcription is fragmented and far behind the present requirements of the systems biology field. To create a comprehensive source of data for cardiovascular gene regulation and to facilitate a deeper understanding of genomic data, the CardioTF database was constructed. The...

journal_title：PeerJ

authors： Zhen Y

更新日期：2016-08-23 00:00:00

abstract：:In the Mississippi River Basin of North America, invasive bigheaded carp (silver carp Hypophthalmichthys molitrix and bighead carp H. nobilis, also referred to as Asian carp) have spread rapidly over the past several decades. In the Illinois River, an important tributary of the Upper Mississippi River, reproduction ap...

journal_title：PeerJ

authors： Gibson-Reinemer DK,Solomon LE,Pendleton RM,Chick JH,Casper AF

更新日期：2017-09-14 00:00:00

abstract：:Although many ecologists focus on the relationship between species richness (S) and evenness (E), conflicts between observation and theory are difficult to reconcile. Empirical S-E relationships were not consistent, while relationships show strong correlation between S and E. Since E essentially depended on the relati...

journal_title：PeerJ

authors： Su Q

更新日期：2018-06-12 00:00:00

abstract：Background:Forest ecosystems are considered among the largest terrestrial carbon sinks. The dynamics of forest carbon depend on where the carbon is stored and its responses to environmental factors, as well as the physiology of the trees. Thus, threatened forest regions with high biodiversity have great scientific impo...

journal_title：PeerJ

authors： González-Cásares M,Pompa-García M,Venegas-González A,Domínguez-Calleros P,Hernández-Díaz J,Carrillo-Parra A,González-Tagle M

更新日期：2019-06-11 00:00:00

abstract：:Although the cellular and molecular responses to exposure to relatively high temperatures (acute thermal stress or heat shock) have been studied previously, only sparse empirical evidence of how it affects cold-water species is available. As climate change becomes more pronounced in areas such as the Western Antarctic...

journal_title：PeerJ

authors： González-Aravena M,Kenny NJ,Osorio M,Font A,Riesgo A,Cárdenas CA

更新日期：2019-12-03 00:00:00

abstract：:Ticks are globally distributed arthropods and a public health concern due to the many human pathogens they carry and transmit, including the causative agent of Lyme disease, Borrelia burgdorferi. As tick species' ranges increase, so do the number of reported tick related illnesses. The microbiome is a critical part of...

journal_title：PeerJ

authors： Gil JC,Helal ZH,Risatti G,Hird SM

更新日期：2020-12-02 00:00:00

abstract：Background:The WRKY transcription factor family plays crucial roles in many aspects of physiological processes and adaption to environment. Although the WRKY genes have been widely identified in various plant species, the structure and function of the WRKY family in sugar beet (Beta vulgaris L.) remains unknown. Metho...

journal_title：PeerJ

authors： Wu GQ,Li ZQ,Cao H,Wang JL

更新日期：2019-10-14 00:00:00

abstract：:The mature spermatozoa of Stephanostomum murielae and Stephanostomoides tenuis are described by transmission electron microscopy. They present several ultrastructural features previously reported in other digeneans. Their spermatozoa possess two axonemes of different length showing the 9 + '1' trepaxonematan pattern, ...

journal_title：PeerJ

authors： Bakhoum AJ,Quilichini Y,Justine JL,Bray RA,Bâ CT,Marchand B

更新日期：2015-02-12 00:00:00

abstract：:We created an easy-to-use device for operant licking experiments and another device that records environmental variables. Both devices use the Raspberry Pi computer to obtain data from multiple input devices (e.g., radio frequency identification tag readers, touch and motion sensors, environmental sensors) and activat...

journal_title：PeerJ

authors： Longley M,Willis EL,Tay CX,Chen H

更新日期：2017-02-14 00:00:00

abstract：:The phosphoinositide 3-kinase (PI3K) pathway shows frequent aberrant alterations and pathological activation in breast cancer cells. While PI3K inhibitors have not achieved expectant therapeutic efficacy in clinical trials, and several studies provide promising combination strategies to substantially maximize therapeu...

journal_title：PeerJ

authors： Qin H,Liu L,Sun S,Zhang D,Sheng J,Li B,Yang W

更新日期：2018-06-19 00:00:00