Analysis of genes and underlying mechanisms involved in foam cells formation and atherosclerosis development.

abstract：:Heterodonty in Crocodylia and closely related taxa has not been defined quantitatively, as the teeth rarely have been measured. This has resulted in a range of qualitative descriptors, with little consensus on the condition of dental morphology in the clade. The purpose of this study is to present a method for the qua...

journal_title：PeerJ

authors： D'Amore DC,Harmon M,Drumheller SK,Testin JJ

更新日期：2019-02-28 00:00:00

abstract：:Small interference RNA has been widely used to suppress gene expression. Three different short hairpin RNAs (shRNAs) against dopamine D1 receptor (Drd1), driven by mouse U6 promoter in self-complementary AAV8 vector (scAAV8), were used to silence mouse striatal Drd1 expression. Transduction of mouse striatum with all ...

journal_title：PeerJ

authors： Ji B,Higa K,Soontornniyomkij V,Miyanohara A,Zhou X

更新日期：2017-10-31 00:00:00

abstract：:Background. Nasal continuous positive airway pressure (nCPAP) is a widely accepted technique of non-invasive respiratory support in premature infants with respiratory distress syndrome due to lack of lung surfactant. If this approach fails, the next step is often intubation, mechanical ventilation (MV) and intratrache...

journal_title：PeerJ

authors： Walther FJ,Hernández-Juviel JM,Waring AJ

更新日期：2014-05-27 00:00:00

abstract：:Changes in soil bacterial communities, which are crucial for the assessment of ecological restoration in Chinese plantations, have never been studied in the "Three North Shelterbelt" project in the semi-arid areas. We used high-throughput sequencing of the 16S rDNA gene to investigate the soil bacterial community dive...

journal_title：PeerJ

authors： Deng J,Zhang Y,Yin Y,Zhu X,Zhu W,Zhou Y

更新日期：2019-06-25 00:00:00

abstract：BACKGROUND:Information on cardiovascular gene transcription is fragmented and far behind the present requirements of the systems biology field. To create a comprehensive source of data for cardiovascular gene regulation and to facilitate a deeper understanding of genomic data, the CardioTF database was constructed. The...

journal_title：PeerJ

authors： Zhen Y

更新日期：2016-08-23 00:00:00

abstract：:In this study we analysed the impact of water regime and soil nutrients on the clonal diversity and genetic variation of the sedge Carex nigra in a central alpine fen. For our analysis, we established 16 study plots randomly distributed over the fen. We determined the exact elevation of each plot as an indicator for t...

journal_title：PeerJ

authors： Reisch C,Meier S,Schmid C,Bartelheimer M

更新日期：2020-06-03 00:00:00

abstract：BACKGROUND:Aspergillus niger, along with many other lignocellulolytic fungi, has been widely used as a commercial workhorse for cellulase production. A fungal cellulase system generally includes three major classes of enzymes i.e., β-glucosidases, endoglucanases and cellobiohydrolases. Cellobiohydrolases (CBH) are vita...

journal_title：PeerJ

authors： Woon JS,Mackeen MM,Illias RM,Mahadi NM,Broughton WJ,Murad AMA,Abu Bakar FD

更新日期：2017-10-12 00:00:00

abstract：:The Asian clam, Corbicula fluminea, is a commonly consumed small freshwater bivalve in East Asia. However, available genetic information of this clam is still limited. In this study, the transcriptome of female C. fluminea was sequenced using the Illumina HiSeq 2500 platform. A total of 89,563 unigenes were assembled ...

journal_title：PeerJ

authors： Zhu C,Zhang L,Ding H,Pan Z

更新日期：2019-10-22 00:00:00

abstract：:The eukaryotic polypyrimidine tract binding protein (PTB) serves primarily as a regulator of alternative splicing of messenger RNA, but is also co-opted to other roles such as RNA localisation and translation initiation from internal ribosome entry sites. The neuronal paralogue of PTB (nPTB) is 75% identical in amino ...

journal_title：PeerJ

authors： Joshi A,Esteve V,Buckroyd AN,Blatter M,Allain FH,Curry S

更新日期：2014-03-13 00:00:00

abstract：:Although C-type cytoplasmic male sterility (CMS-C) is one of the most attractive tools for maize hybrid seed production, the detailed regulation network of the male sterility remains unclear. In order to identify the CMS-C sterility associated genes and/or pathways, the comparison of the transcriptomes between the CMS...

journal_title：PeerJ

authors： Li C,Zhao Z,Liu Y,Liang B,Guan S,Lan H,Wang J,Lu Y,Cao M

更新日期：2017-05-30 00:00:00

abstract：:Genome rearrangements have played an important role in the evolution of Yersinia pestis from its progenitor Yersinia pseudotuberculosis. Traditional phylogenetic trees for Y. pestis based on sequence comparison have short internal branches and low bootstrap supports as only a small number of nucleotide substitutions h...

journal_title：PeerJ

authors： Bochkareva OO,Dranenko NO,Ocheredko ES,Kanevsky GM,Lozinsky YN,Khalaycheva VA,Artamonova II,Gelfand MS

更新日期：2018-03-27 00:00:00

abstract：:Biological control, a globally-important ecosystem service, can provide long-term and broad-scale suppression of invasive pests, weeds and pathogens in natural, urban and agricultural environments. Following (few) historic cases that led to sizeable environmental up-sets, the discipline of arthropod biological control...

journal_title：PeerJ

authors： Wyckhuys KAG,Wongtiem P,Rauf A,Thancharoen A,Heimpel GE,Le NTT,Fanani MZ,Gurr GM,Lundgren JG,Burra DD,Palao LK,Hyman G,Graziosi I,Le VX,Cock MJW,Tscharntke T,Wratten SD,Nguyen LV,You M,Lu Y,Ketelaar JW,Goergen G

更新日期：2018-10-19 00:00:00

abstract：:Global warming can significantly affect many aspects of the biology of animal species, including their thermal physiology and physiological performance. Thermal performance curves provide a heuristic model to evaluate the impacts of temperature on the ecophysiology of ectotherms. When integrated with other thermal bio...

journal_title：PeerJ

authors： Cabezas-Cartes F,Fernández JB,Duran F,Kubisch EL

更新日期：2019-08-09 00:00:00

abstract：:Many migratory bird species show high levels of site fidelity to their wintering sites, which confers advantages due to prior knowledge, but may also limit the ability of the individual to move away from degrading sites or to detect alternative foraging opportunities. Winter site fidelity often varies among age groups...

journal_title：PeerJ

authors： Lourenço PM,Alves JA,Reneerkens J,Loonstra AJ,Potts PM,Granadeiro JP,Catry T

更新日期：2016-09-28 00:00:00

abstract：:Protoporphyrin (PP) and biliverdin (BV) give rise to the enormous diversity in avian egg coloration. Egg color serves several ecological purposes, including post-mating signaling and camouflage. Egg camouflage represents a major character of open-nesting birds which accomplish protection of their unhatched offspring a...

journal_title：PeerJ

authors： Wiemann J,Yang TR,Sander PN,Schneider M,Engeser M,Kath-Schorr S,Müller CE,Sander PM

更新日期：2017-08-29 00:00:00

abstract：:Muscle mass loss and wasting are characteristic features of patients with chronic conditions including cancer. Therapeutic options are still scarce. We hypothesized that cachexia-induced muscle oxidative stress may be attenuated in response to treatment with beta2-adrenoceptor-selective agonist formoterol in rats. In ...

journal_title：PeerJ

authors： Salazar-Degracia A,Busquets S,Argilés JM,López-Soriano FJ,Barreiro E

更新日期：2017-12-13 00:00:00

abstract：:The ichthyoplankton assemblage structure in the Yangtze Estuary was analyzed based on four springs in 1999, 2001, 2004 and 2007 in order to provide detailed characterizations of the ichthyoplankton assemblage in springs, examine the long-term dynamics of spring ichthyoplankton assemblages, and evaluate the influence o...

journal_title：PeerJ

authors： Zhang H,Xian W,Liu S

更新日期：2015-08-18 00:00:00

abstract：:Recent years have seen a growing awareness of the role the immune system plays in successful cancer treatment, especially in novel therapies like immunotherapy. The characterization of the immunological composition of tumors and their micro-environment is thus becoming a necessity. In this paper we introduce a deep le...

journal_title：PeerJ

authors： Aprupe L,Litjens G,Brinker TJ,van der Laak J,Grabe N

更新日期：2019-04-10 00:00:00

abstract：:Grouping large genomic fragments assembled from shotgun metagenomic sequences to deconvolute complex microbial communities, or metagenome binning, enables the study of individual organisms and their interactions. Because of the complex nature of these communities, existing metagenome binning methods often miss a large...

journal_title：PeerJ

authors： Kang DD,Froula J,Egan R,Wang Z

更新日期：2015-08-27 00:00:00

abstract：:Coastal birds are critical ecosystem constituents on sandy shores, yet are threatened by depressed reproductive success resulting from direct and indirect anthropogenic and natural pressures. Few studies examine clutch fate across the wide range of environments experienced by birds; instead, most focus at the small si...

journal_title：PeerJ

authors： Maslo B,Schlacher TA,Weston MA,Huijbers CM,Anderson C,Gilby BL,Olds AD,Connolly RM,Schoeman DS

更新日期：2016-09-13 00:00:00

abstract：:Autophagy serves as a turnover mechanism for the recycling of redundant and/or damaged macromolecules present in eukaryotic cells to re-use them under starvation conditions via a double-membrane structure known as autophagosome. A set of eukaryotic genes called autophagy-related genes (ATGs) orchestrate this highly el...

journal_title：PeerJ

authors： Aslan E,Küçükoğlu N,Arslanyolu M

更新日期：2017-01-17 00:00:00

abstract：:Cellulosic waste represents a significant and underutilized carbon source for the biofuel industry. Owing to the recalcitrance of crystalline cellulose to enzymatic degradation, it is necessary to design economical methods of liberating the fermentable sugars required for bioethanol production. One route towards unloc...

journal_title：PeerJ

authors： Hamberg Y,Ruimy-Israeli V,Dassa B,Barak Y,Lamed R,Cameron K,Fontes CM,Bayer EA,Fried DB

更新日期：2014-10-30 00:00:00

abstract：:The massive influx of pelagic Sargassum spp. (sargasso) into the Mexican Caribbean Sea has caused major deterioration of the coastal environment and has affected the tourism industry as well as livelihoods since 2015. Species of Sargassum have high capacity to absorb metals; thus, leachates of sargasso may contribute ...

journal_title：PeerJ

authors： Rodríguez-Martínez RE,Roy PD,Torrescano-Valle N,Cabanillas-Terán N,Carrillo-Domínguez S,Collado-Vides L,García-Sánchez M,van Tussenbroek BI

更新日期：2020-02-26 00:00:00

abstract：:Populations of passively dispersed organisms in continental aquatic habitats typically show high levels of neutral genetic differentiation despite their high dispersal capabilities. Several evolutionary factors, including founder events, local adaptation, and life cycle features such as high population growth rates an...

journal_title：PeerJ

authors： Montero-Pau J,Gómez A,Serra M

更新日期：2018-12-11 00:00:00

abstract：:Streptococcus pneumoniae remains the leading causative pathogen in pediatric pneumonia and bacteremia throughout the world. The invasive pneumococcal disease (IPD) is known as isolation of S. pneumoniae from a normally sterile site (e.g., blood, cerebrospinal fluid, synovial fluid, pericardial fluid, pleural fluid, or...

journal_title：PeerJ

authors： Chiu NC,Chi H,Peng CC,Chang HY,Huang DT,Chang L,Lei WT,Lin CY

更新日期：2017-01-25 00:00:00

abstract：Background:To ensure the safety of trees, two NDT (nondestructive testing) techniques, electric resistance tomography and stress wave tomography, were employed to quantitatively detect and characterize the internal decay of standing trees. Comparisons between those two techniques were done to make full use of the indiv...

journal_title：PeerJ

authors： Yue X,Wang L,Wacker JP,Zhu Z

更新日期：2019-03-05 00:00:00

abstract：Introduction:Human papillomavirus (HPV) is the most common sexually transmitted infection (STI) worldwide. Despite recommendations for HPV vaccination of young women from health authorities, parental concerns were raised whether vaccination could induce unsafe sexual behaviour in young women. Therefore, the primary aim...

journal_title：PeerJ

authors： Soudeyns C,Speybroeck N,Brisson M,Mossong J,Latsuzbaia A

更新日期：2020-02-10 00:00:00

abstract：:In group-living animals, heterogeneity in individuals' social connections may mediate the sharing of microbial infectious agents. In this regard, the genetic relatedness of individuals' commensal gut bacterium Escherichia coli may be ideal to assess the potential for pathogen transmission through animal social network...

journal_title：PeerJ

authors： Balasubramaniam K,Beisner B,Guan J,Vandeleest J,Fushing H,Atwill E,McCowan B

更新日期：2018-01-17 00:00:00

abstract：OBJECTIVES:Compare the immediate effects of a Neurodynamic Mobilization (NM) treatment or foam roller (FR) treatment after DOMS. DESIGN:Double blind randomised clinical trial. SETTING:The participants performed 100 drop jumps (5 sets of 20 repetitions, separated by 2 min rests) from a 0.5-m high box in a University b...

journal_title：PeerJ

authors： Romero-Moraleda B,La Touche R,Lerma-Lara S,Ferrer-Peña R,Paredes V,Peinado AB,Muñoz-García D

更新日期：2017-10-13 00:00:00

abstract：:Wildlife demography is typically studied at a single point in time within a year when species, often during the reproductive season, are more active and therefore easier to find. However, this provides only a low-resolution glimpse into demographic temporal patterns over time and may hamper a more complete understandi...

journal_title：PeerJ

authors： Guimarães M,Correa DT,Gaiarsa MP,Kéry M

更新日期：2020-02-25 00:00:00