Androgen up-regulation of Twist1 gene expression is mediated by ETV1.

abstract：:Current ovarian cancer treatment involves chemotherapy that has serious limitations, such as rapid clearance, unfavorable biodistribution and severe side effects. To overcome these limitations, drug delivery systems (DDS) have been developed to encapsulate chemotherapeutics for delivery to tumor cells. However, no sys...

journal_title：PeerJ

authors： Raavé R,de Vries RB,Massuger LF,van Kuppevelt TH,Daamen WF

更新日期：2015-12-10 00:00:00

abstract：Background:It was well known that age has an impact on word processing (word frequency or predictability) in terms of fixating time during reading. However, little is known about whether or not age modulates these impacts on saccade behaviors in Chinese reading (i.e., length of incoming/outgoing saccades for a target w...

journal_title：PeerJ

authors： Liu Z,Tong W,Su Y

更新日期：2020-04-01 00:00:00

abstract：:A wide range of biotic stresses (BS) and abiotic stresses (AS) adversely affect plant growth and productivity worldwide. The study of individual genes cannot be considered as an effective approach for the understanding of tolerance mechanisms, since these stresses are frequent and often in combination with each other,...

journal_title：PeerJ

authors： Ashrafi-Dehkordi E,Alemzadeh A,Tanaka N,Razi H

更新日期：2018-07-17 00:00:00

abstract：:In contrast to dominant mode of ecological transition in the evolution of marine mammals, different lineages of toothed whales (Odontoceti) have repeatedly invaded freshwater ecosystems during the Cenozoic era. The so-called 'river dolphins' are now recognized as independent lineages that converged on similar morpholo...

journal_title：PeerJ

authors： Pyenson ND,Vélez-Juarbe J,Gutstein CS,Little H,Vigil D,O'Dea A

更新日期：2015-09-01 00:00:00

abstract：:Multimodal imaging enables sensitive measures of the architecture and integrity of the human brain, but the high-dimensional nature of advanced brain imaging features poses inherent challenges for the analyses and interpretations. Multivariate age prediction reduces the dimensionality to one biologically informative s...

journal_title：PeerJ

authors： Richard G,Kolskår K,Sanders AM,Kaufmann T,Petersen A,Doan NT,Monereo Sánchez J,Alnæs D,Ulrichsen KM,Dørum ES,Andreassen OA,Nordvik JE,Westlye LT

更新日期：2018-11-30 00:00:00

abstract：Background:Several field studies have used fuel-cell breathalysers (FCB) to investigate the prevalence of alcohol intoxication. However, there is a lack of evidence evaluating the psychometric properties of these breathalysers outside of the forensic disciplines. Methods:The current research describes four studies des...

journal_title：PeerJ

authors： Sorbello JG,Devilly GJ,Allen C,Hughes LRJ,Brown K

更新日期：2018-03-14 00:00:00

abstract：Background:Immunoglobulin superfamily member 10 (IGSF10) is a member of the immunoglobulin superfamily that is expressed at high levels in both the gallbladder and ovary. Currently, the role and possible mechanism of IGSF10 in breast cancer remain unclear. Method:By applying real-time quantitative polymerase chain rea...

journal_title：PeerJ

authors： Wang M,Dai M,Wu YS,Yi Z,Li Y,Ren G

更新日期：2020-10-21 00:00:00

abstract：Background:Converging evidence comparing barefoot (BF) and shod (SH) running highlights differences in foot-strike patterns and somatosensory feedback, among others. Anecdotal evidence from SH runners attempting BF running suggests a greater attentional demand may be experienced during BF running. However, little work ...

journal_title：PeerJ

authors： Snow NJ,Blair JFL,MacDonald GZ,Byrne JM,Basset FA

更新日期：2018-04-09 00:00:00

abstract：Background:Laminitis is a common equine disease characterized by foot pain, and is commonly diagnosed using a five-grade Obel system developed in 1948 using sepsis-related cases. However, endocrinopathic laminitis is now the most common form of the disease and clinical signs may be mild, or spread across two Obel grade...

journal_title：PeerJ

authors： Meier A,de Laat M,Pollitt C,Walsh D,McGree J,Reiche DB,von Salis-Soglio M,Wells-Smith L,Mengeler U,Mesa Salas D,Droegemueller S,Sillence MN

更新日期：2019-06-07 00:00:00

abstract：:Spermatological characteristics of species from two monorchiid genera, Opisthomonorchis and Paramonorcheides, have been investigated, for the first time, by means of transmission electron microscopy. The ultrastructural study reveals that the mature spermatozoon of Opisthomonorchis dinema and Paramonorcheides selaris ...

journal_title：PeerJ

authors： Quilichini Y,Bakhoum AJ,Justine JL,Bray RA,Bâ CT,Marchand B

更新日期：2016-09-20 00:00:00

abstract：Background:In this study cull dairy cows from six California dairy herds were sampled seasonally over the course of a year. The objectives were to determine the prevalence of antimicrobial resistant (AMR) Salmonella spp. shed in cull cow feces, and the factors associated with fecal shedding of AMR and multidrug resista...

journal_title：PeerJ

authors： Pereira R,Williams DR,Rossitto P,Adaska J,Okello E,Champagne J,Lehenbauer TW,Li X,Chase J,Nguyen T,Pires AFA,Atwill ER,Aly SS

更新日期：2019-03-21 00:00:00

abstract：Background:This study assessed whether serum lipid levels are associated with the risk of symptomatic intracerebral hemorrhage (sICH) and functional outcomes in patients with acute ischemic stroke after receiving intravenous thrombolysis. Methods:We retrospectively analyzed consecutive ischemic stroke patients who wer...

journal_title：PeerJ

authors： Lin TC,Lin YK,Chen CI,Chan L,Chi NF,Yuan RY,Sheu JJ,Wei CR,Tsai JP,Yeh TH

更新日期：2018-11-23 00:00:00

abstract：:We provided chimpanzees (Pan troglodytes) with the ability to improve the quality of food rewards they received in a dyadic test of inequity. We were interested to see if this provision influenced their responses and, if so, whether it was mediated by a social partner's outcomes. We tested eight dyads using an exchang...

journal_title：PeerJ

authors： Hopper LM,Lambeth SP,Schapiro SJ,Brosnan SF

更新日期：2013-09-17 00:00:00

abstract：:The Eocene history of cetacean evolution is now represented by the expansive fossil record of archaeocetes elucidating major morphofunctional shifts relating to the land to sea transition, but the change from archaeocetes to modern cetaceans is poorly established. New fossil material of the recently recognized family ...

journal_title：PeerJ

authors： Boessenecker RW,Fordyce RE

更新日期：2015-09-10 00:00:00

abstract：BACKGROUND:VSEARCH is an open source and free of charge multithreaded 64-bit tool for processing and preparing metagenomics, genomics and population genomics nucleotide sequence data. It is designed as an alternative to the widely used USEARCH tool (Edgar, 2010) for which the source code is not publicly available, algo...

journal_title：PeerJ

authors： Rognes T,Flouri T,Nichols B,Quince C,Mahé F

更新日期：2016-10-18 00:00:00

abstract：:To investigate community shelter effects of two invasive decapod species, Hemigrapsus sanguineus and Carcinus maenas, in the Long Island Sound (LIS), we deployed artificial shelters in the intertidal and immediate subtidal zones. These consisted of five groups during the summer: a control, a resident H. sanguineus mal...

journal_title：PeerJ

authors： Hudson DM,Reagan D,Crivello JF

更新日期：2016-07-27 00:00:00

abstract：BACKGROUND:Recent climatic history has strongly impacted plant populations, but little is known about its effect on microbes. Alders, which host few and specific symbionts, have high genetic diversity in glacial refugia. Here, we tested the prediction that communities of root symbionts survived in refugia with their ho...

journal_title：PeerJ

authors： Roy M,Pozzi AC,Gareil R,Nagati M,Manzi S,Nouioui I,Sharikadze N,Jargeat P,Gryta H,Moreau PA,Fernandez MP,Gardes M

更新日期：2017-07-18 00:00:00

abstract：Background:Proper glycemic control is an important goal of critical care medicine, including perioperative patient care that can influence patients' prognosis. Insulin secretion from pancreatic β-cells is generally assumed to play a critical role in glycemic control in response to an elevated blood glucose concentratio...

journal_title：PeerJ

authors： Kusunoki M,Hayashi M,Shoji T,Uba T,Tanaka H,Sumi C,Matsuo Y,Hirota K

更新日期：2019-12-02 00:00:00

abstract：:Currently there are 21 shrimp species in the northeastern Atlantic and Mediterranean Sea which are considered to belong to the superfamily Oplophoroidea, but the larval development is unknown for most of them. The complete larval development of Systellaspis debilis (Milne-Edwards, 1881), here described and illustrated...

journal_title：PeerJ

authors： Bartilotti C,Dos Santos A

更新日期：2019-09-18 00:00:00

abstract：:Establishing a diverse gut microbiota after birth is being increasingly recognised as important for preventing illnesses later in life. It is well established that bacterial diversity rapidly increases post-partum; however, few studies have examined the infant gut virome/phageome during this developmental period. We p...

journal_title：PeerJ

authors： McCann A,Ryan FJ,Stockdale SR,Dalmasso M,Blake T,Ryan CA,Stanton C,Mills S,Ross PR,Hill C

更新日期：2018-05-07 00:00:00

abstract：Objectives:The purpose of this study is to investigate the patterns of complementary and alternative medicine use and its association with time to conventional treatment. Design:A cross-sectional study design was designed. Setting and participants:The study was performed at the Chonburi Cancer Hospital, with chart re...

journal_title：PeerJ

authors： Chotipanich A,Sooksrisawat C,Jittiworapan B

更新日期：2019-06-14 00:00:00

abstract：Introduction:Knowledge Translation (KT) is expected to be a critical learning outcome of a Continuing Professional Development (CPD) program. It continues to serve as an area of interest among educators and healthcare providers due to its importance to evidence-based practice. This study endeavored to develop a valid a...

journal_title：PeerJ

authors： Ong IL,Diño MJS,Calimag MMP,Hidalgo FA

更新日期：2018-08-13 00:00:00

abstract：:Background. Pollinators, which provide the agriculturally and ecologically essential service of pollination, are under threat at a global scale. Habitat loss and homogenisation, pesticides, parasites and pathogens, invasive species, and climate change have been identified as past and current threats to pollinators. Ac...

journal_title：PeerJ

authors： Brown MJ,Dicks LV,Paxton RJ,Baldock KC,Barron AB,Chauzat MP,Freitas BM,Goulson D,Jepsen S,Kremen C,Li J,Neumann P,Pattemore DE,Potts SG,Schweiger O,Seymour CL,Stout JC

更新日期：2016-08-09 00:00:00

abstract：:Network motifs play an important role in the structural analysis of biological networks. Identification of such network motifs leads to many important applications such as understanding the modularity and the large-scale structure of biological networks, classification of networks into super-families, and protein func...

journal_title：PeerJ

authors： Patra S,Mohapatra A

更新日期：2019-05-17 00:00:00

abstract：:As coral reefs continue to decline globally, coral restoration practitioners have explored various approaches to return coral cover and diversity to decimated reefs. While branching coral species have long been the focus of restoration efforts, the recent development of the microfragmentation coral propagation techniq...

journal_title：PeerJ

authors： Koval G,Rivas N,D'Alessandro M,Hesley D,Santos R,Lirman D

更新日期：2020-10-02 00:00:00

abstract：Background:Alcohol-related hepatocellular carcinoma (HCC) was reported to be diagnosed at a later stage, but the mechanism was unknown. This study aimed to identify special key genes (SKGs) during alcohol-related HCC development and progression. Methods:The mRNA data of 369 HCC patients and the clinical information we...

journal_title：PeerJ

authors： Zhang X,Kang C,Li N,Liu X,Zhang J,Gao F,Dai L

更新日期：2019-02-06 00:00:00

abstract：:Background. Genome-wide association studies have succeeded in detecting novel common variants which associate with complex diseases. As a result of the fast changes in next generation sequencing technology, a large number of sequencing data are generated, which offers great opportunities to identify rare variants that...

journal_title：PeerJ

authors： Sun L,Wang C,Hu YQ

更新日期：2016-06-16 00:00:00

abstract：:Background. Nasal continuous positive airway pressure (nCPAP) is a widely accepted technique of non-invasive respiratory support in premature infants with respiratory distress syndrome due to lack of lung surfactant. If this approach fails, the next step is often intubation, mechanical ventilation (MV) and intratrache...

journal_title：PeerJ

authors： Walther FJ,Hernández-Juviel JM,Waring AJ

更新日期：2014-05-27 00:00:00

abstract：:Meniscal tears are a common cause of stifle lameness in dogs. Use of autologous synoviocytes from the affected stifle is an attractive cell source for tissue engineering replacement fibrocartilage. However, the diseased state of these cells may impede in vitro fibrocartilage formation. Synoviocytes from 12 osteoarthri...

journal_title：PeerJ

authors： Warnock JJ,Bobe G,Duesterdieck-Zellmer KF

更新日期：2014-09-30 00:00:00

abstract：:Trihelix transcription factors play multiple roles in plant growth, development and various stress responses. In this study, we identified 71 trihelix family genes in the soybean genome. These trihelix genes were located at 19 out of 20 soybean chromosomes unevenly and were classified into six distinct subfamilies: GT...

journal_title：PeerJ

authors： Liu W,Zhang Y,Li W,Lin Y,Wang C,Xu R,Zhang L

更新日期：2020-03-13 00:00:00