The incidence rates of endometrial hyperplasia and endometrial cancer: a four-year population-based study.

abstract：Background:Selective serotonin reuptake inhibitors (SSRIs) are among the most widely prescribed class of drugs in the practice of psychiatry. Cytochrome P450 (CYP) 2C19 and CYP2D6 are established as clinically relevant drug metabolizing enzymes (DMEs) that influence the pharmacokinetics of SSRIs and may either be group...

journal_title：PeerJ

authors： Eugene AR

更新日期：2019-10-09 00:00:00

abstract：:As the most widely distributed snake in Eurasia, the adder (Vipera berus) has been extensively investigated in Europe but poorly understood in Asia. The Southern Altay Mountains represent the adder's southern distribution limit in Central Asia, whereas its population status has never been assessed. We conducted, for t...

journal_title：PeerJ

authors： Cui S,Luo X,Chen D,Sun J,Chu H,Li C,Jiang Z

更新日期：2016-08-16 00:00:00

abstract：:The objectives of this experiment were to determine the effects of graded dietary lead (Pb) concentrations on body weight and Pb concentrations in blood, hair, soft tissues, and urine from pigs and to generate equations for estimating daily Pb intake. Sixteen barrows with initial body weight 36.3 kg (standard deviatio...

journal_title：PeerJ

authors： Reddy KE,Park KR,Lee SD,Yoo JH,Son AR,Lee HJ

更新日期：2017-11-01 00:00:00

abstract：Background:The association between asthma (AS), allergic rhinitis (AR) and oral diseases remains inconclusive in adults. AS and AR often coexist. However, studies that investigate AS, AR together and their association with oral diseases are scarce. Methods:Data from 22,898 men and 28,541 women, aged 21 to 25 years, we...

journal_title：PeerJ

authors： Ho SW,Lue KH,Ku MS

更新日期：2019-09-10 00:00:00

abstract：:There is growing concern that some bee populations are in decline, potentially threatening pollination security in agricultural and non-agricultural landscapes. Among the numerous causes associated with this trend, nutritional stress resulting from a mismatch between bee nutritional needs and plant community provision...

journal_title：PeerJ

authors： Pamminger T,Becker R,Himmelreich S,Schneider CW,Bergtold M

更新日期：2019-02-27 00:00:00

abstract：:Ethylene response factors (ERFs) are plant-specific transcription factors (TFs) that play important roles in plant growth and stress defense and have received a great amount of attention in recent years. In this study, seven ERF genes related to abiotic stress tolerance and response were identified in plants of the Po...

journal_title：PeerJ

authors： Huang J,Wang S,Wang X,Fan Y,Han Y

更新日期：2020-10-20 00:00:00

abstract：:Chloroplasts are typically inherited from the female parent and are haploid in most angiosperms, but rare intra-individual heteroplasmy in plastid genomes has been reported in plants. Here, we report an example of plastome heteroplasmy and its characteristics in Gentiana tongolensis (Gentianaceae). The plastid genome ...

journal_title：PeerJ

authors： Sun SS,Zhou XJ,Li ZZ,Song HY,Long ZC,Fu PC

更新日期：2019-11-27 00:00:00

abstract：:Recent upperward migration of plants and animals along altitudinal gradients and poleward movement of animal range boundaries have been confirmed by many studies. This phenomenon is considered to be part of the fingerprint of recent climate change on the biosphere. Here I examine whether poleward movement is occurring...

journal_title：PeerJ

authors： Groom QJ

更新日期：2013-05-28 00:00:00

abstract：:The Asian clam, Corbicula fluminea, is a commonly consumed small freshwater bivalve in East Asia. However, available genetic information of this clam is still limited. In this study, the transcriptome of female C. fluminea was sequenced using the Illumina HiSeq 2500 platform. A total of 89,563 unigenes were assembled ...

journal_title：PeerJ

authors： Zhu C,Zhang L,Ding H,Pan Z

更新日期：2019-10-22 00:00:00

abstract：Background:Leucojum aestivum L. is an important medicinal plant which produces Amaryllidaceae alkaloids, especially galanthamine and lycorine. Research is currently exploring the possibility of producing these alkaloids using biotechnological methods, including in vitro cultures. The biosynthesis of alkaloids may be af...

journal_title：PeerJ

authors： Ptak A,Morańska E,Skrzypek E,Warchoł M,Spina R,Laurain-Mattar D,Simlat M

更新日期：2020-03-16 00:00:00

abstract：Background:Experiencing an adequate amount of cold temperatures over winter is necessary for many temperate tree species to break dormancy and flower in spring. Thus, changes in winter and spring temperatures associated with climate change may influence when trees break dormancy and flower in the future. There have bee...

journal_title：PeerJ

authors： Prevéy JS,Harrington CA

更新日期：2018-09-25 00:00:00

abstract：:Herbivory and nutrient enrichment are drivers of benthic dynamics of coral reef macroalgae; however, their impact may vary seasonally. In this study we evaluated the effects of herbivore pressure, nutrient availability and potential propagule supply on seasonal recruitment and succession of macroalgal communities on a...

journal_title：PeerJ

authors： Duran A,Collado-Vides L,Burkepile DE

更新日期：2016-11-02 00:00:00

abstract：:Spatial genetic variation of river-dwelling freshwater fishes is typically affected by the historical and contemporary river landscape as well as life-history traits. Tropical river and stream landscapes have endured extended geological change, shaping the existing pattern of genetic diversity, but were not directly a...

journal_title：PeerJ

authors： Jaisuk C,Senanan W

更新日期：2018-03-07 00:00:00

abstract：:Coral diseases are a leading factor contributing to the global decline of coral reefs, and yet mechanisms of disease transmission remain poorly understood. This study tested whether zooplankton can act as a vector for white band disease (WBD) in Acropora cervicornis. Natural zooplankton communities were collected from...

journal_title：PeerJ

authors： Certner RH,Dwyer AM,Patterson MR,Vollmer SV

更新日期：2017-07-07 00:00:00

abstract：:We investigated population dynamics, breeding pairs, breeding habitat selection, nest density, distance between neighboring nests, nest survival, reproductive success, and recruitment rate for Black-necked Cranes (BNC, Grus nigricollis) during 2013-2015 in Yanchiwan National Nature Reserve (YCW), Gansu, China. Numbers...

journal_title：PeerJ

authors： Zhang L,An B,Shu M,Yang X

更新日期：2017-01-31 00:00:00

abstract：Background:Alzheimer's disease (AD) is a prevalent progressive neurodegenerative human disease whose cause remains unclear. Numerous initially highly hopeful anti-AD drugs based on the amyloid-β (Aβ) hypothesis of AD have failed recent late-phase tests. Natural aging (AG) is a high-risk factor for AD. Here, we aim to g...

journal_title：PeerJ

authors： Peng YS,Tang CW,Peng YY,Chang H,Chen CL,Guo SL,Wu LC,Huang MC,Lee HC

更新日期：2020-03-20 00:00:00

abstract：:Alzheimer's disease is a multifactorial disorder caused by the interaction of genetic, epigenetic and environmental factors. The formation of cytotoxic oligomers consisting of Aβ peptide is widely accepted as being one of the main key events triggering the development of Alzheimer's disease. Aβ peptide production resu...

journal_title：PeerJ

authors： Parenti N,Del Grosso A,Antoni C,Cecchini M,Corradetti R,Pavone FS,Calamai M

更新日期：2017-04-12 00:00:00

abstract：:Using hypothetical scenarios, we provided participants with potential opening statements to a conflict discussion that varied on I/you language and communicated perspective. Participants rated the likelihood that the recipient of the statement would react in a defensive manner. Using I-language and communicating persp...

journal_title：PeerJ

authors： Rogers SL,Howieson J,Neame C

更新日期：2018-05-18 00:00:00

abstract：Background:Cognitive dysfunction in fibromyalgia (FM) encompasses objective cognitive difficulties, as measured in neuropsychological tests, and self-reported cognitive complaints. Although it has been suggested that FM patients display problems in working memory, the data are inconsistent, and the overall working memo...

journal_title：PeerJ

authors： Pidal-Miranda M,González-Villar AJ,Carrillo-de-la-Peña MT,Andrade E,Rodríguez-Salgado D

更新日期：2018-11-21 00:00:00

abstract：:Background. Just as for most other tortoise species, the once common Chaco tortoise, Chelonoidis chilensis (Testudinidae), is under constant threat across it distribution in Argentina, Bolivia and Paraguay. Despite initial qualitative description of the species distribution and further individual reports of new locati...

journal_title：PeerJ

authors： Ruete A,Leynaud GC

更新日期：2015-10-01 00:00:00

abstract：Background:Over the last two decades, there has been a constant increase in prescription rates of antidepressants. In parallel, neuroactive pharmaceuticals are making their way into aquatic environments at increasing concentrations. Among the antidepressants detected in the environment citalopram, a selective serotonin...

journal_title：PeerJ

authors： Ziegler M,Knoll S,Köhler HR,Tisler S,Huhn C,Zwiener C,Triebskorn R

更新日期：2020-03-12 00:00:00

abstract：:Non-invasive measurements of glucocorticoid (GC) concentrations, including cortisol and corticosterone, serve as reliable indicators of adrenocortical activities and physiological stress loads in a variety of species. As an alternative to invasive analyses based on plasma, GC concentrations in saliva still represent s...

journal_title：PeerJ

authors： Nemeth M,Pschernig E,Wallner B,Millesi E

更新日期：2016-01-18 00:00:00

abstract：:Seasonality impacts species distributions through changes of the environmental conditions that affect the presence of individuals at a given place. Although the dynamics of cave microclimates are well known, only a few studies have evaluated the effects of such dynamics on non-strictly cave species. Here we assessed i...

journal_title：PeerJ

authors： Lunghi E,Manenti R,Ficetola GF

更新日期：2017-05-10 00:00:00

abstract：BACKGROUND:Profiling of microbial communities via metagenomic shotgun sequencing has enabled researches to gain unprecedented insight into microbial community structure and the functional roles of community members. This study describes a method and basic analysis for a metagenomic adaptation of the double digest restr...

journal_title：PeerJ

authors： Liu MY,Worden P,Monahan LG,DeMaere MZ,Burke CM,Djordjevic SP,Charles IG,Darling AE

更新日期：2017-09-19 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess the effects of age, body condition score (BCS) and muscle condition score (MCS) on indirect radial and coccygeal Doppler systolic arterial blood pressure (SAP) measurements in dogs. METHODS:Sixty-two privately-owned dogs were enrolled between June and July 2016. The BC...

journal_title：PeerJ

authors： Mooney AP,Mawby DI,Price JM,Whittemore JC

更新日期：2017-03-22 00:00:00

abstract：:Afrotheria is a strongly supported clade within placental mammals, but morphological synapomorphies for the entire group have only recently come to light. Soft tissue characters represent an underutilized source of data for phylogenetic analysis, but nonetheless provide features shared by some or all members of Afroth...

journal_title：PeerJ

authors： Brocklehurst RJ,Crumpton N,Button E,Asher RJ

更新日期：2016-04-12 00:00:00

abstract：:Trees in the Morus genera belong to the Moraceae family. To better understand the species status of genus Morus and to provide information for studies on evolutionary biology within the genus, the complete chloroplast (cp) genomes of M. cathayana and M. multicaulis were sequenced. The plastomes of the two species are ...

journal_title：PeerJ

authors： Kong WQ,Yang JH

更新日期：2017-03-08 00:00:00

abstract：:The shifting baseline syndrome describes a gradual lowering of human cognitive baselines, as each generation accepts a lower standard of resource abundance or size as the new norm. There is strong empirical evidence of declining trends of abundance and body sizes of marine fish species reported from docks and markets....

journal_title：PeerJ

authors： Francis FT,Howard BR,Berchtold AE,Branch TA,Chaves LCT,Dunic JC,Favaro B,Jeffrey KM,Malpica-Cruz L,Maslowski N,Schultz JA,Smith NS,Côté IM

更新日期：2019-02-15 00:00:00

abstract：:Climatic variables have been the main predictors employed in ecological niche modeling and species distribution modeling, although biotic interactions are known to affect species' spatial distributions via mechanisms such as predation, competition, and mutualism. Biotic interactions can affect species' responses to ab...

journal_title：PeerJ

authors： Simões MVP,Peterson AT

更新日期：2018-12-05 00:00:00

abstract：:Herein, we identified the tomato SlMYB102 gene as a MYB family transcription factor of the R2R3-MYB subfamily. We additionally determined that the SlMYB102 promoter region contains photoresponsive, abiotic stress-responsive, and hormone-responsive regulatory elements, and we detected higher SlMYB102 expression in the ...

journal_title：PeerJ

authors： Wang M,Hao J,Chen X,Zhang X

更新日期：2020-10-07 00:00:00