Broad cognitive complaints but subtle objective working memory impairment in fibromyalgia patients.

Abstract:

Background:Cognitive dysfunction in fibromyalgia (FM) encompasses objective cognitive difficulties, as measured in neuropsychological tests, and self-reported cognitive complaints. Although it has been suggested that FM patients display problems in working memory, the data are inconsistent, and the overall working memory status of the patients is unclear. It is also not clear whether the working memory problems are related to cognitive complaints or how the dyscognition is affected by the characteristic clinical symptoms of FM. Methods:To clarify these aspects, we explored the neuropsychological performance for different components of working memory and the subjective self-perception of cognitive status in a sample of 38 women with FM. They were compared with a matched group of 32 healthy women. Results:Our findings suggested that the FM patients do not differ from healthy controls in their overall working memory functioning. Only a poor performance was found in a single task of visuospatial working memory, mediated by the presence of depressive symptoms, fatigue and pain. The FM patients also displayed a higher level of perception of cognitive difficulties than healthy controls, and this difference was mediated by depression and fatigue. Furthermore, cognitive complaints in FM patients were only associated with a lower verbal WM capacity. Discussion:FM patients have a subtle specific impairment in their working memory functioning, as well as elevated concern about their cognitive status. These findings suggest a disconnection between neuropsychological performance and subjective complaints. In FM patients, clinical variables such as pain, fatigue, and depression play an important role in dyscognition, as assessed by both objective and subjective measures, and should be taken into account in future research.

journal_name

PeerJ

journal_title

PeerJ

authors

Pidal-Miranda M,González-Villar AJ,Carrillo-de-la-Peña MT,Andrade E,Rodríguez-Salgado D

doi

10.7717/peerj.5907

subject

Has Abstract

pub_date

2018-11-21 00:00:00

pages

e5907

issn

2167-8359

pii

5907

journal_volume

6

pub_type

杂志文章

相关文献

PeerJ文献大全
  • Analysis of the light intensity dependence of the growth of Synechocystis and of the light distribution in a photobioreactor energized by 635 nm light.

    abstract::Synechocystis gathered momentum in modelling studies and biotechnological applications owing to multiple factors like fast growth, ability to fix carbon dioxide into valuable products, and the relative ease of genetic manipulation. Synechocystis physiology and metabolism, and consequently, the productivity of Synechoc...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.5256

    authors: Cordara A,Re A,Pagliano C,Van Alphen P,Pirone R,Saracco G,Branco Dos Santos F,Hellingwerf K,Vasile N

    更新日期:2018-07-27 00:00:00

  • The effect of reverse transcription enzymes and conditions on high throughput amplicon sequencing of the 16S rRNA.

    abstract::It is assumed that the sequencing of ribosomes better reflects the active microbial community than the sequencing of the ribosomal RNA encoding genes. Yet, many studies exploring microbial communities in various environments, ranging from the human gut to deep oceans, questioned the validity of this paradigm due to th...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.7608

    authors: Šťovíček A,Cohen-Chalamish S,Gillor O

    更新日期:2019-10-25 00:00:00

  • Reference gene selection for qRT-PCR assays in Stellera chamaejasme subjected to abiotic stresses and hormone treatments based on transcriptome datasets.

    abstract:Background:Stellera chamaejasme Linn, an important poisonous plant of the China grassland, is toxic to humans and livestock. The rapid expansion of S. chamaejasme has greatly damaged the grassland ecology and, consequently, seriously endangered the development of animal husbandry. To draft efficient prevention and cont...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.4535

    authors: Liu X,Guan H,Song M,Fu Y,Han X,Lei M,Ren J,Guo B,He W,Wei Y

    更新日期:2018-04-03 00:00:00

  • Comparison of incisional complications between skin closures using a simple continuous or intradermal pattern: a pilot study in horses undergoing ventral median celiotomy.

    abstract:Background:Development of incisional complications following ventral median celiotomy might depend on suture pattern for skin closure. Methods:In this prospective study, 21 healthy male horses underwent celiotomy. Skin closure was either performed via a continuous percutaneous pattern (CO group; 5 warmbloods/5 ponies)...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.5772

    authors: Scharner D,Gittel C,Winter K,Blaue D,Schedlbauer C,Vervuert I,Brehm W

    更新日期:2018-11-09 00:00:00

  • Improving decolorization of dyes by laccase from Bacillus licheniformis by random and site-directed mutagenesis.

    abstract:Background:Dye wastewater increases cancer risk in humans. For the treatment of dyestuffs, biodegradation has the advantages of economy, high efficiency, and environmental protection compared with traditional physical and chemical methods. Laccase is the best candidate for dye degradation because of its multiple substr...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.10267

    authors: Bu T,Yang R,Zhang Y,Cai Y,Tang Z,Li C,Wu Q,Chen H

    更新日期:2020-11-11 00:00:00

  • Relative telomere length and oxidative DNA damage in hypertrophic ligamentum flavum of lumbar spinal stenosis.

    abstract:Background:Lumbar spinal stenosis (LSS) is a common cause of low back pain with degenerative spinal change in older adults. Telomeres are repetitive nucleoprotein DNA sequences of TTAGGG at the ends of chromosomes. Oxidative stress originates from an imbalance in pro-oxidant and antioxidant homeostasis that results in ...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.5381

    authors: Dechsupa S,Yingsakmongkol W,Limthongkul W,Singhatanadgige W,Honsawek S

    更新日期:2018-08-09 00:00:00

  • Occurrence of Terranova larval types (Nematoda: Anisakidae) in Australian marine fish with comments on their specific identities.

    abstract::Pseudoterranovosis is a well-known human disease caused by anisakid larvae belonging to the genus Pseudoterranova. Human infection occurs after consuming infected fish. Hence the presence of Pseudoterranova larvae in the flesh of the fish can cause serious losses and problems for the seafood, fishing and fisheries ind...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.1722

    authors: Shamsi S,Suthar J

    更新日期:2016-03-15 00:00:00

  • 2D versus 3D real time ultrasound with live xPlane imaging to visualize aortic and ductal arches: comparison between methods.

    abstract:Background:The diagnosis of congenital heart defects is challenging, especially for what concerns conotruncal anomalies. Indeed, although the screening techniques of fetal cardiac anomalies have greatly improved, the detection rate of conotruncal anomalies still remains low due to the fact that they are associated with...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.4561

    authors: Dell'Oro S,Verderio M,Incerti M,Mastrolia SA,Cozzolino S,Vergani P

    更新日期:2018-04-06 00:00:00

  • Isthminia panamensis, a new fossil inioid (Mammalia, Cetacea) from the Chagres Formation of Panama and the evolution of 'river dolphins' in the Americas.

    abstract::In contrast to dominant mode of ecological transition in the evolution of marine mammals, different lineages of toothed whales (Odontoceti) have repeatedly invaded freshwater ecosystems during the Cenozoic era. The so-called 'river dolphins' are now recognized as independent lineages that converged on similar morpholo...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.1227

    authors: Pyenson ND,Vélez-Juarbe J,Gutstein CS,Little H,Vigil D,O'Dea A

    更新日期:2015-09-01 00:00:00

  • A comparative in-silico analysis of autophagy proteins in ciliates.

    abstract::Autophagy serves as a turnover mechanism for the recycling of redundant and/or damaged macromolecules present in eukaryotic cells to re-use them under starvation conditions via a double-membrane structure known as autophagosome. A set of eukaryotic genes called autophagy-related genes (ATGs) orchestrate this highly el...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.2878

    authors: Aslan E,Küçükoğlu N,Arslanyolu M

    更新日期:2017-01-17 00:00:00

  • Effectiveness of adaptive silverware on range of motion of the hand.

    abstract::Background. Hand function is essential to a person's self-efficacy and greatly affects quality of life. Adapted utensils with handles of increased diameters have historically been used to assist individuals with arthritis or other hand disabilities for feeding, and other related activities of daily living. To date, mi...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.1667

    authors: McDonald SS,Levine D,Richards J,Aguilar L

    更新日期:2016-02-15 00:00:00

  • Boat anchoring contributes substantially to coral reef degradation in the British Virgin Islands.

    abstract::Community decline is often linked to anthropogenic activities. Coral reef declines, for example, have been linked to overfishing and climate change, but impacts of coastal development, pollution, and tourism have received increasing attention. Here, we isolated the impact of one little-studied aspect of recreational a...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.7010

    authors: Flynn RL,Forrester GE

    更新日期:2019-05-23 00:00:00

  • Co-father relationships among the Suruí (Paiter) of Brazil.

    abstract::Partible paternity refers to the conception belief that children can have multiple fathers ("co-fathers") and is common to indigenous cultures of lowland South America. The nature of social relationships observed between co-fathers reveals information about the reproductive strategies underlying partible paternity. He...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.899

    authors: Walker RS,Yvinec C,Ellsworth RM,Bailey DH

    更新日期:2015-04-14 00:00:00

  • Human feeding biomechanics: performance, variation, and functional constraints.

    abstract::The evolution of the modern human (Homo sapiens) cranium is characterized by a reduction in the size of the feeding system, including reductions in the size of the facial skeleton, postcanine teeth, and the muscles involved in biting and chewing. The conventional view hypothesizes that gracilization of the human feedi...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.2242

    authors: Ledogar JA,Dechow PC,Wang Q,Gharpure PH,Gordon AD,Baab KL,Smith AL,Weber GW,Grosse IR,Ross CF,Richmond BG,Wright BW,Byron C,Wroe S,Strait DS

    更新日期:2016-07-26 00:00:00

  • Effects of different ablation points of renal denervation on the efficacy of resistant hypertension.

    abstract:Objective:To explore the blood pressure response to different ablation points of renal denervation (RDN) in patients with resistant hypertension. Methods:A total of 42 cases with resistant hypertension treated by RDN in our center from 2013 to 2015 were retrospectively analyzed. The patients were divided into two grou...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.9842

    authors: Zhang H,Li LY,Xiao RX,Zhang TC,Liu ZJ,Gao JQ

    更新日期:2020-09-15 00:00:00

  • Comparative proteomics reveals that YK51, a 4-Hydroxypandurantin-A analogue, downregulates the expression of proteins associated with dengue virus infection.

    abstract::Dengue is endemic throughout tropical and subtropical regions of the world. Currently, there is no clinically approved therapeutic drug available for this acute viral infection. Although the first dengue vaccine Dengvaxia has been approved for use in certain countries, it is limited to those without a previous dengue ...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.3939

    authors: Tan WL,Lee YK,Ho YF,Yusof R,Abdul Rahman N,Karsani SA

    更新日期:2018-01-30 00:00:00

  • Expression of leptin and leptin receptors in colorectal cancer-an immunohistochemical study.

    abstract::Obesity is demonstrated to be a risk factor in the development of cancers of various organs, such as colon, prostate, pancreas and so on. Leptine (LEP) is the most renowned of the adipokines. As a hormone, it mediates its effect through leptin receptor (LEPR), which is widely expressed in various tissues including col...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.7624

    authors: Al-Shibli SM,Harun N,Ashour AE,Mohd Kasmuri MHB,Mizan S

    更新日期:2019-10-02 00:00:00

  • Zooplankton as a potential vector for white band disease transmission in the endangered coral, Acropora cervicornis.

    abstract::Coral diseases are a leading factor contributing to the global decline of coral reefs, and yet mechanisms of disease transmission remain poorly understood. This study tested whether zooplankton can act as a vector for white band disease (WBD) in Acropora cervicornis. Natural zooplankton communities were collected from...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.3502

    authors: Certner RH,Dwyer AM,Patterson MR,Vollmer SV

    更新日期:2017-07-07 00:00:00

  • Evolution of Philodendron (Araceae) species in Neotropical biomes.

    abstract::Philodendron is the second most diverse genus of the Araceae, a tropical monocot family with significant morphological diversity along its wide geographic distribution in the Neotropics. Although evolutionary studies of Philodendron were conducted in recent years, the phylogenetic relationship among its species remain...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.1744

    authors: Loss-Oliveira L,Sakuragui C,Soares Mde L,Schrago CG

    更新日期:2016-03-24 00:00:00

  • Comparisons of eccentric knee flexor strength and asymmetries across elite, sub-elite and school level cricket players.

    abstract::Background. There has been a continual increase in injury rates in cricket, with hamstring strain injuries (HSIs) being the most prominent. Eccentric knee flexor weakness and bilateral asymmetries are major modifiable risk factors for future HSIs. However, there is a lack of data relating to eccentric hamstring streng...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.1594

    authors: Chalker WJ,Shield AJ,Opar DA,Keogh JW

    更新日期:2016-02-18 00:00:00

  • The nectar report: quantitative review of nectar sugar concentrations offered by bee visited flowers in agricultural and non-agricultural landscapes.

    abstract::There is growing concern that some bee populations are in decline, potentially threatening pollination security in agricultural and non-agricultural landscapes. Among the numerous causes associated with this trend, nutritional stress resulting from a mismatch between bee nutritional needs and plant community provision...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.6329

    authors: Pamminger T,Becker R,Himmelreich S,Schneider CW,Bergtold M

    更新日期:2019-02-27 00:00:00

  • Multi-scale relationship between land use/land cover types and water quality in different pollution source areas in Fuxian Lake Basin.

    abstract::The spatial-temporal evolution of land use and land cover (LULC) and its multi-scale impact on the water environment is becoming highly significant in the LULC research field. The current research results show that the more significant scale impact on LULC and water quality in the whole basin and the riparian buffer s...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.7283

    authors: Li S,Peng S,Jin B,Zhou J,Li Y

    更新日期:2019-07-15 00:00:00

  • I understand you feel that way, but I feel this way: the benefits of I-language and communicating perspective during conflict.

    abstract::Using hypothetical scenarios, we provided participants with potential opening statements to a conflict discussion that varied on I/you language and communicated perspective. Participants rated the likelihood that the recipient of the statement would react in a defensive manner. Using I-language and communicating persp...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.4831

    authors: Rogers SL,Howieson J,Neame C

    更新日期:2018-05-18 00:00:00

  • Microgeographic variation in body condition of three Mexican garter snakes in central Mexico.

    abstract:Background:Geographic variation in body size and condition can reveal differential local adaptation to resource availability or climatic factors. Body size and condition are related to fitness in garter snakes (Thamnophis), thus good body condition may increase survival, fecundity in females, and mating success in male...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.6601

    authors: Valencia-Flores E,Venegas-Barrera CS,Fajardo V,Manjarrez J

    更新日期:2019-03-13 00:00:00

  • Transcriptome-wide characterization and functional analysis of MATE transporters in response to aluminum toxicity in Medicago sativa L.

    abstract::Multidrug and toxic compound extrusion (MATE) transporters contribute to multidrug resistance and play major determinants of aluminum (Al) tolerance in plants. Alfalfa (Medicago sativa L.) is the most extensively cultivated forage crop in the world, yet most alfalfa cultivars are not Al tolerant. The basic knowledge o...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.6302

    authors: Min X,Jin X,Liu W,Wei X,Zhang Z,Ndayambaza B,Wang Y

    更新日期:2019-01-31 00:00:00

  • Increased copy number of syncytin-1 in the trophectoderm is associated with implantation of the blastocyst.

    abstract:Background:A key step in embryo implantation is the adhesion to and invasion of the endometrium by the blastocyst trophectoderm. The envelope proteins of HERV-W and -FRD (human endogenous retrovirus-W and -FRD), syncytin-1 and syncytin-2, are mainly distributed in the placenta, and play important roles in the developme...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.10368

    authors: Guo L,Gu F,Xu Y,Zhou C

    更新日期:2020-11-17 00:00:00

  • Tweet success? Scientific communication correlates with increased citations in Ecology and Conservation.

    abstract::Science communication is seen as critical for the disciplines of ecology and conservation, where research products are often used to shape policy and decision making. Scientists are increasing their online media communication, via social media and news. Such media engagement has been thought to influence or predict tr...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.4564

    authors: Lamb CT,Gilbert SL,Ford AT

    更新日期:2018-04-12 00:00:00

  • Validation of endogenous reference genes in rat cerebral cortex for RT-qPCR analyses in developmental toxicity studies.

    abstract::Relative gene expression data obtained from quantitative RT-PCR (RT-qPCR) experiments are dependent on appropriate normalization to represent true values. It is common to use constitutively expressed endogenous reference genes (RGs) for normalization, but for this strategy to be valid the RGs must be stably expressed ...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.7181

    authors: Ramhøj L,Axelstad M,Svingen T

    更新日期:2019-06-26 00:00:00

  • Mismatches between the genetic and phenotypic sex in the wild Kou population of Nile tilapia Oreochromis niloticus.

    abstract::Sex determination and sex chromosomes can be very diverse between teleost species. The group of tilapias shows a polymorphism in sex determination not only between closely related species but also between domestic strains within a species. In the Nile tilapia, the major effect genes and therefore the Y chromosome have...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.7709

    authors: Sissao R,D'Cotta H,Baroiller JF,Toguyeni A

    更新日期:2019-09-18 00:00:00

  • Short-term starvation at low temperature prior to harvest does not impact the health and acute stress response of adult Atlantic salmon.

    abstract::A period of starvation is regarded as a sound practice in aquaculture prior to handling, transportation and harvest, to minimise impacts on welfare and ensure proper hygiene after harvest. However, documentation of welfare issues such as stress following starvation and handling in adult Atlantic salmon are lacking. Th...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.3273

    authors: Waagbø R,Jørgensen SM,Timmerhaus G,Breck O,Olsvik PA

    更新日期:2017-04-27 00:00:00