Relative telomere length and oxidative DNA damage in hypertrophic ligamentum flavum of lumbar spinal stenosis.

abstract：AIMS:Mountain ranges in the tropics are characterised by high levels of localised endemism, often-aberrant evolutionary trajectories, and some of the world's most diverse regional biotas. Here we investigate the evolution of montane endemism, ecology and body size in a clade of direct-developing frogs (Choerophryne, Mi...

journal_title：PeerJ

authors： Oliver PM,Iannella A,Richards SJ,Lee MS

更新日期：2017-03-30 00:00:00

abstract：:Diarrhea is a syndrome of digestive disorders in young rabbits and may lead to secondary infections resulting in reduced immunity and higher mortality in baby rabbits, with serious impacts on rabbit farming. In this study, we investigated the effects of diarrhea on the health of baby rabbits in terms of intestinal muc...

journal_title：PeerJ

authors： Chen Y,Zhao B,Wu Y,Hu S,Mu L,Zhu C,Pan Y,Wu X

更新日期：2017-11-27 00:00:00

abstract：Background:Humpback whales (Megaptera novaeangliae) are a widespread, vocal baleen whale best known for producing song, a complex, repetitive, geographically distinct acoustic signal sung by males, predominantly in a breeding context. Humpback whales worldwide also produce non-song vocalizations ("calls") throughout th...

journal_title：PeerJ

authors： Fournet MEH,Jacobsen L,Gabriele CM,Mellinger DK,Klinck H

更新日期：2018-07-30 00:00:00

abstract：Background:Parkinson's disease (PD) is the second most common neurodegenerative disorder. In addition to its highly debilitating motor symptoms, non-motor symptoms may precede their motor counterparts by many years, which may characterize a prodromal phase of PD. A potential pharmacological strategy is to introduce neu...

journal_title：PeerJ

authors： Benvenutti R,Marcon M,Reis CG,Nery LR,Miguel C,Herrmann AP,Vianna MRM,Piato A

更新日期：2018-06-01 00:00:00

abstract：Background:Overweight (OW) is considered a risk for various metabolic diseases. However, its effects as a mechanism that alters the metabolite profiles remain unclear. The purpose of this study is to investigate the effects that OW has on the lipid and metabolite profiles in young adults. Methods:The serum metabolite ...

journal_title：PeerJ

authors： Pasanta D,Chancharunee S,Tungjai M,Kim HJ,Kothan S

更新日期：2019-06-20 00:00:00

abstract：:The mammalian pelvis is thought to exhibit adaptations to the functional demands of locomotor behaviors. Previous work in primates has identified form-function relationships between pelvic shape and locomotor behavior; few studies have documented such relationships in carnivorans, instead focusing on long bones. Most ...

journal_title：PeerJ

authors： Lewton KL,Brankovic R,Byrd WA,Cruz D,Morales J,Shin S

更新日期：2020-02-20 00:00:00

abstract：:The monoamines serotonin and dopamine are important neuromodulators present in the central nervous system, known to be active regulators of social behaviour in fish as in other vertebrates. Our aim was to investigate the region-specific brain monoaminergic differences arising when individual cleaners face a client (mu...

journal_title：PeerJ

authors： de Abreu MS,Messias JPM,Thörnqvist PO,Winberg S,Soares MC

更新日期：2018-05-24 00:00:00

abstract：:Root hairs are unicellular elongations of certain rhizodermal cells that improve the uptake of sparingly soluble and immobile soil nutrients. Among different Arabidopsis thaliana genotypes, root hair density, length and the local acclimation to low inorganic phosphate (Pi) differs considerably, when analyzed on split ...

journal_title：PeerJ

authors： Stetter MG,Benz M,Ludewig U

更新日期：2017-01-24 00:00:00

abstract：:Multidrug and toxic compound extrusion (MATE) transporters contribute to multidrug resistance and play major determinants of aluminum (Al) tolerance in plants. Alfalfa (Medicago sativa L.) is the most extensively cultivated forage crop in the world, yet most alfalfa cultivars are not Al tolerant. The basic knowledge o...

journal_title：PeerJ

authors： Min X,Jin X,Liu W,Wei X,Zhang Z,Ndayambaza B,Wang Y

更新日期：2019-01-31 00:00:00

abstract：Background:In arid environments, plant primary productivity is generally low and highly variable both spatially and temporally. Resources are not evenly distributed in space and time (e.g., soil nutrients, water), and depend on global (El Niño/ Southern Oscillation) and local climate parameters. The launch of the Senti...

journal_title：PeerJ

authors： Funghi C,Heim RHJ,Schuett W,Griffith SC,Oldeland J

更新日期：2020-05-26 00:00:00

abstract：:I used radio-telemetry to track the movements of Mangrove Cuckoos (Coccyzus minor) captured in southwest Florida. Relatively little is known about the natural history of Mangrove Cuckoos, and my goal was to provide an initial description of how individuals use space, with a focus on the size and placement of home rang...

journal_title：PeerJ

authors： Lloyd JD

更新日期：2017-06-30 00:00:00

abstract：:Sex differences in some preferences and motivations are well established, but it is unclear whether they persist in selective sub-populations, such as expert financial decision makers, top scientists, or elite athletes. We addressed this issue by studying competitiveness in 1,147 varsity intercollegiate distance runne...

journal_title：PeerJ

authors： Deaner RO,Lowen A,Rogers W,Saksa E

更新日期：2015-04-21 00:00:00

abstract：:Combination Index (CI) analysis suggested that MBIC and doxorubicin synergistically inhibited up to 97% of cell proliferation in ER+/PR+MCF-7 and triple negative MDA-MB-231 breast cancer cell lines. Moreover, treatment of the breast cancer cells with the combined drugs resulted in lower IC50 values in contrast to the ...

journal_title：PeerJ

authors： Hasanpourghadi M,Abdul Majid N,Rais Mustafa M

更新日期：2018-09-17 00:00:00

abstract：:Inflammation is critical in the dysregulated growth of adipose tissue and associated vascular dysfunctions. 15-Lipoxygenase metabolites, important mediators of inflammation in adipose tissue during obese conditions, may contribute to codependence of inflammation and angiogenesis in adipose tissue. We have already repo...

journal_title：PeerJ

authors： Soumya SJ,Binu S,Helen A,Reddanna P,Sudhakaran PR

更新日期：2014-10-21 00:00:00

abstract：:Ethylene response factors (ERFs) are plant-specific transcription factors (TFs) that play important roles in plant growth and stress defense and have received a great amount of attention in recent years. In this study, seven ERF genes related to abiotic stress tolerance and response were identified in plants of the Po...

journal_title：PeerJ

authors： Huang J,Wang S,Wang X,Fan Y,Han Y

更新日期：2020-10-20 00:00:00

abstract：Background:As key negative regulators of gene expression, microRNAs (miRNAs) play an important role in the onset and progression of hepatocellular carcinoma (HCC). This study aimed to identify the miRNAs involved in HCC carcinogenesis and their regulated genes. Methods:The Gene Expression Omnibus (GEO) dataset (GSE108...

journal_title：PeerJ

authors： Liu Y,Cao Y,Cai W,Wu L,Zhao P,Liu XG

更新日期：2020-04-29 00:00:00

abstract：:Mitochondria are small, energy-producing structures vital to the energy needs of the body. Genetic mutations cause mitochondria to fail to produce the energy needed by cells and organs which can cause severe disease and death. These genetic mutations are likely to be in the mitochondrial DNA (mtDNA), or possibly in th...

journal_title：PeerJ

authors： Ahuja AS

更新日期：2018-05-21 00:00:00

abstract：:Spermatological characteristics of species from two monorchiid genera, Opisthomonorchis and Paramonorcheides, have been investigated, for the first time, by means of transmission electron microscopy. The ultrastructural study reveals that the mature spermatozoon of Opisthomonorchis dinema and Paramonorcheides selaris ...

journal_title：PeerJ

authors： Quilichini Y,Bakhoum AJ,Justine JL,Bray RA,Bâ CT,Marchand B

更新日期：2016-09-20 00:00:00

abstract：:Climate change will significantly affect plant distribution as well as the quality of medicinal plants. Although numerous studies have analyzed the effect of climate change on future habitats of plants through species distribution models (SDMs), few of them have incorporated the change of effective content of medicina...

journal_title：PeerJ

authors： Guo Y,Wei H,Lu C,Gao B,Gu W

更新日期：2016-10-20 00:00:00

abstract：:The role of glial cells in pain modulation has recently gathered attention. The objective of this study was to determine healthy spinal microglia and astrocyte morphology and disposition in equine spinal cord dorsal horns using Iba-1 and GFAP/Cx-43 immunofluorescence labeling, respectively. Five adult horses without v...

journal_title：PeerJ

authors： Meneses CS,Müller HY,Herzberg DE,Uberti B,Bustamante HA,Werner MP

更新日期：2017-10-27 00:00:00

abstract：:This study aimed to investigate the effects of Clostridium butyricum as a dietary probiotic supplement in fishmeal based diet on growth, gut microbiota and immune performance of marron (Cherax cainii). Marron were randomly distributed into two different treatment groups, control and probiotic fed group. After 42 days ...

journal_title：PeerJ

authors： Foysal MJ,Nguyen TTT,Chaklader MR,Siddik MAB,Tay CY,Fotedar R,Gupta SK

更新日期：2019-08-27 00:00:00

abstract：Background & Aims:Endothelial precursor cell (EPC) dysfunction is one of the risk factors for diabetes mellitus (DM) which results in delayed wound healing. Rosiglitazone (RSG) is a frequently prescribed oral glucose-lowering drug. Previous studies have shown the positive effects of RSG on ameliorating EPC dysfunction ...

journal_title：PeerJ

authors： Zhou G,Han X,Wu Z,Shi Q,Bao X

更新日期：2019-10-17 00:00:00

abstract：:On the purpose of enhancing the forensic efficiency of CODIS STR loci, new STR loci have been gradually discovered and developed into some commercial multiplex systems. Recently, 22 STR loci including 18 non-CODIS STR loci and four CODIS STR loci were investigated in 501 unrelated healthy individuals of Kazakh ethnic ...

journal_title：PeerJ

authors： Chen C,Guo Y,Jin X,Cui W,Wei Y,Fang Y,Lan Q,Kong T,Xie T,Zhu B

更新日期：2019-04-25 00:00:00

abstract：Background:Human population growth has led to biodiversity declines in tropical cities. While habitat loss and fragmentation have been the main drivers of urban biodiversity loss, man-made interventions to reduce health risks have also emerged as an unintentional threat. For instance, insecticide fogging to control mos...

journal_title：PeerJ

authors： Lee NSM,Clements GR,Ting ASY,Wong ZH,Yek SH

更新日期：2020-10-01 00:00:00

abstract：Background:Adnexal torsion is a gynecologic emergency that requires surgical treatment. In this study, we reviewed the surgical outcomes of women with adnexal torsion in eastern Taiwan (Hualien county, area 4,629 km2, 330,000 residents). Methods:This retrospective study included 42 women diagnosed with surgically-prov...

journal_title：PeerJ

authors： Huang C,Hong MK,Chu TY,Ding DC

更新日期：2018-12-04 00:00:00

abstract：:The Drosophila melanogaster P transposable element provides one of the best cases of horizontal transfer of a mobile DNA sequence in eukaryotes. Invasion of natural populations by the P element has led to a syndrome of phenotypes known as P-M hybrid dysgenesis that emerges when strains differing in their P element com...

journal_title：PeerJ

authors： Bergman CM,Han S,Nelson MG,Bondarenko V,Kozeretska I

更新日期：2017-09-15 00:00:00

abstract：Background:The microRNAs (miRNAs) have been validated as prognostic markers in many cancers. Here, we aimed at developing a miRNA-based signature for predicting the prognosis of esophagus adenocarcinoma (EAC). Methods:The RNA-sequencing data set of EAC was downloaded from The Cancer Genome Atlas (TCGA). Eighty-four pa...

journal_title：PeerJ

authors： Lan T,Lu Y,Xiao Z,Xu H,He J,Hu Z,Mao W

更新日期：2019-07-25 00:00:00

abstract：Background:In the predator-sea urchin-macrophyte trophic cascade, the ecological effect of sea urchins as grazers depends both on their density and the changes in foraging activity, which are influenced by various disturbing factors. However, the complete duration of the alarm reactions of echinoids has not been studie...

journal_title：PeerJ

authors： Zhadan PM,Vaschenko MA

更新日期：2019-11-22 00:00:00

abstract：:Callinectes sapidus Rathbun, 1896 is a western Atlantic species with a disjointed natural geographic range from Massachusetts, USA to Venezuela (distribution area 1) and from Alagoas, Brazil to northern Argentina (distribution area 2). It is the only species of portunid crab commercially harvested in the continental U...

journal_title：PeerJ

authors： Windsor AM,Moore MK,Warner KA,Stadig SR,Deeds JR

更新日期：2019-11-05 00:00:00

abstract：Background:Although integrated pest management (IPM) is essential for conservation agriculture, this method can be inadequate for severely infected fields. The ability to predict the potential occurrence of severe infestation of soil-borne disease would enable farmers to adopt suitable methods for high-risk areas, such...

journal_title：PeerJ

authors： Ikeda K,Osawa T

更新日期：2020-11-17 00:00:00