N-acetylcysteine protects against motor, optomotor and morphological deficits induced by 6-OHDA in zebrafish larvae.

abstract：:This paper investigates the capabilities of the evolutionary fuzzy genetic (FG) approach and compares it with three neuro-fuzzy methods-neuro-fuzzy with grid partitioning (ANFIS-GP), neuro-fuzzy with subtractive clustering (ANFIS-SC), and neuro-fuzzy with fuzzy c-means clustering (ANFIS-FCM)-in terms of modeling long-...

journal_title：PeerJ

authors： Sadeghi-Niaraki A,Kisi O,Choi SM

更新日期：2020-08-14 00:00:00

abstract：:The active place avoidance task is a dry-arena task used to assess spatial navigation and memory in rodents. In this task, a subject is put on a rotating circular arena and avoids an invisible sector that is stable in relation to the room. Rotation of the arena means that the subject's avoidance must be active, otherw...

journal_title：PeerJ

authors： Bahník Š,Stuchlík A

更新日期：2015-09-22 00:00:00

abstract：:The ε subunit from ATP synthases acts as an ATP sensor in the bacterial cell to prevent ATP hydrolysis and thus the waste of ATP under conditions of low ATP concentration. However, the ATP binding affinities from various bacterial organisms differ markedly, over several orders of magnitude. For example, the ATP syntha...

journal_title：PeerJ

authors： Krah A,Bond PJ

更新日期：2018-09-05 00:00:00

abstract：Background:Evidences indicated that non-small-cell lung cancer (NSCLC) and small-cell lung cancer (SCLC) might originate from the same cell type, which however ended up to be two different subtypes of lung carcinoma, requiring different therapeutic regimens. We aimed to identify the differences between these two subtyp...

journal_title：PeerJ

authors： Wu J,Hao Z,Ma C,Li P,Dang L,Sun S

更新日期：2020-04-23 00:00:00

abstract：Background:This study postulates that underlying environmental conditions and a susceptible population's socio-economic status should be explored simultaneously to adequately understand a vector borne disease infection risk. Here we focus on West Nile Virus (WNV), a mosquito borne pathogen, as a case study for spatial ...

journal_title：PeerJ

authors： Kala AK,Atkinson SF,Tiwari C

更新日期：2020-07-27 00:00:00

abstract：:Chloroplasts are typically inherited from the female parent and are haploid in most angiosperms, but rare intra-individual heteroplasmy in plastid genomes has been reported in plants. Here, we report an example of plastome heteroplasmy and its characteristics in Gentiana tongolensis (Gentianaceae). The plastid genome ...

journal_title：PeerJ

authors： Sun SS,Zhou XJ,Li ZZ,Song HY,Long ZC,Fu PC

更新日期：2019-11-27 00:00:00

abstract：:The study investigates the solution of the multicollinearity between certain body measurements of Romanov lambs and prediction of the body weight of Romanov lambs using the thus calculated factor analysis scores and a multiple regression model. For this purpose, the body measurements (wither height (WH), croup height ...

journal_title：PeerJ

authors： Tahtali Y

更新日期：2019-08-01 00:00:00

abstract：:Many migratory bird species show high levels of site fidelity to their wintering sites, which confers advantages due to prior knowledge, but may also limit the ability of the individual to move away from degrading sites or to detect alternative foraging opportunities. Winter site fidelity often varies among age groups...

journal_title：PeerJ

authors： Lourenço PM,Alves JA,Reneerkens J,Loonstra AJ,Potts PM,Granadeiro JP,Catry T

更新日期：2016-09-28 00:00:00

abstract：:The most intense commercial harvest of marine aquarium species in North America occurs in the coastal waters surrounding Florida, yet very often little information exists on the life histories, population dynamics, or reproductive characteristics of these organisms. The peppermint shrimp Lysmata boggessi is one such s...

journal_title：PeerJ

authors： Dickson MD,Behringer DC,Baeza JA

更新日期：2020-01-23 00:00:00

abstract：:Trees in the Morus genera belong to the Moraceae family. To better understand the species status of genus Morus and to provide information for studies on evolutionary biology within the genus, the complete chloroplast (cp) genomes of M. cathayana and M. multicaulis were sequenced. The plastomes of the two species are ...

journal_title：PeerJ

authors： Kong WQ,Yang JH

更新日期：2017-03-08 00:00:00

abstract：:Histone deacetylases (HDACs) are key epigenetic factors in regulating chromatin structure and gene expression in multiple aspects of plant growth, development, and response to abiotic or biotic stresses. Many studies on systematic analysis and molecular function of HDACs in Arabidopsis and rice have been conducted. Ho...

journal_title：PeerJ

authors： Zhang K,Yu L,Pang X,Cao H,Si H,Zang J,Xing J,Dong J

更新日期：2020-02-12 00:00:00

abstract：Background:Adnexal torsion is a gynecologic emergency that requires surgical treatment. In this study, we reviewed the surgical outcomes of women with adnexal torsion in eastern Taiwan (Hualien county, area 4,629 km2, 330,000 residents). Methods:This retrospective study included 42 women diagnosed with surgically-prov...

journal_title：PeerJ

authors： Huang C,Hong MK,Chu TY,Ding DC

更新日期：2018-12-04 00:00:00

abstract：Background:Patellofemoral pain (PFP) is often reported as a diffuse pain at the front of the knee during knee-loading activities. A patient's description of pain location and distribution is commonly drawn on paper by clinicians, which is difficult to quantify, report and compare within and between patients. One way of...

journal_title：PeerJ

authors： Matthews M,Rathleff MS,Vicenzino B,Boudreau SA

更新日期：2018-03-08 00:00:00

abstract：:Soil microbial communities are continuously exposed to H2 diffusing into the soil from the atmosphere. N2-fixing nodules represent a peculiar microniche in soil where H2 can reach concentrations up to 20,000 fold higher than in the global atmosphere (0.530 ppmv). In this study, we investigated the impact of H2 exposur...

journal_title：PeerJ

authors： Piché-Choquette S,Tremblay J,Tringe SG,Constant P

更新日期：2016-03-10 00:00:00

abstract：:Pantoea stewartii subsp. stewartii is a bacterial phytopathogen that causes Stewart's wilt disease in corn. It uses quorum sensing to regulate expression of some genes involved in virulence in a cell density-dependent manner as the bacterial population grows from small numbers at the initial infection site in the leaf...

journal_title：PeerJ

authors： Packard H,Kernell Burke A,Jensen RV,Stevens AM

更新日期：2017-04-27 00:00:00

abstract：:Loud calls are used by many species as long-distance signals for group defense, mate attraction, and inter- and intragroup spacing. Chimpanzee loud calls, or pant hoots, are used in a variety of contexts including group coordination and during male contests. Here, we observed an alpha male takeover in wild chimpanzees...

journal_title：PeerJ

authors： Kalan AK,Boesch C

更新日期：2018-06-28 00:00:00

abstract：:Fear is a response to a known threat, anxiety is a response to a perceived threat. Both of these affective states can be detrimental to animal welfare in modern housing environments. In comparison to the well-validated tests for assessing fear in laying hens, tests for measuring anxiety are less developed. Perception ...

journal_title：PeerJ

authors： Campbell DLM,Taylor PS,Hernandez CE,Stewart M,Belson S,Lee C

更新日期：2019-07-10 00:00:00

abstract：Background:The current cultivation and plant breeding of Honeybush tea (produced from members of Cyclopia Vent.) do not consider the genetic diversity nor structuring of wild populations. Thus, wild populations may be at risk of genetic contamination if cultivated plants are grown in the same landscape. Here, we invest...

journal_title：PeerJ

authors： Galuszynski NC,Potts AJ

更新日期：2020-09-02 00:00:00

abstract：:Dorsal horn neurons in the spinal cord integrate and relay sensory information to higher brain centers. These neurons are organized in specific laminae and different transcription factors are involved in their specification. The murine homeodomain Gbx1 protein is expressed in the mantle zone of the spinal cord at E12....

journal_title：PeerJ

authors： Meziane H,Fraulob V,Riet F,Krezel W,Selloum M,Geffarth M,Acampora D,Hérault Y,Simeone A,Brand M,Dollé P,Rhinn M

更新日期：2013-08-29 00:00:00

abstract：:Tyrosine phosphorylation has emerged as an important regulator of plasma membrane-localized immune receptors activity. Here, we investigate the role of tyrosine phosphorylation in the regulation of rice XANTHOMONAS RESISTANCE 21 (XA21)-mediated immunity. We demonstrate that the juxtamembrane and kinase domain of Esche...

journal_title：PeerJ

authors： Caddell DF,Wei T,Sharma S,Oh MH,Park CJ,Canlas P,Huber SC,Ronald PC

更新日期：2018-12-11 00:00:00

abstract：Background:Morphological differentiation between populations resulting from local adaptations to environmental conditions is likely to be more pronounced in populations with increasing genetic isolation. In a previous study a positive clinal variation in body size was observed in isolated Roesel's bush-cricket, Metriop...

journal_title：PeerJ

authors： Kaňuch P,Kiehl B,Cassel-Lundhagen A,Laugen AT,Low M,Berggren Å

更新日期：2020-10-22 00:00:00

abstract：:In this study, silver nanoparticles (NP) were synthesized by two methods: using an aqueous extract of Mentha spicata leaves and using citrate ions as stabilizing agent, and the cytotoxicity and anticancer activity of both NP were evaluated in vitro. The particles synthesized with the aqueous extract were spherical wit...

journal_title：PeerJ

authors： Torres-Martínez Y,Arredondo-Espinoza E,Puente C,González-Santiago O,Pineda-Aguilar N,Balderas-Rentería I,López I,Ramírez-Cabrera MA

更新日期：2019-12-09 00:00:00

abstract：:Coral diseases are a leading factor contributing to the global decline of coral reefs, and yet mechanisms of disease transmission remain poorly understood. This study tested whether zooplankton can act as a vector for white band disease (WBD) in Acropora cervicornis. Natural zooplankton communities were collected from...

journal_title：PeerJ

authors： Certner RH,Dwyer AM,Patterson MR,Vollmer SV

更新日期：2017-07-07 00:00:00

abstract：:Recent improvements in next-generation sequencing (NGS) technologies can facilitate the obtainment of mitochondrial genomes. However, it is not clear whether NGS could be effectively used to reconstruct the mitogenome with high gene rearrangement. These high rearrangements would cause amplification failure, and/or ass...

journal_title：PeerJ

authors： Yuan S,Xia Y,Zheng Y,Zeng X

更新日期：2016-12-15 00:00:00

abstract：:Dilated cardiomyopathy is a prevalent and often fatal disease in humans and dogs. Indeed dilated cardiomyopathy is the third most common form of cardiac disease in humans, reported to affect approximately 36 individuals per 100,000 individuals. In dogs, dilated cardiomyopathy is the second most common cardiac disease ...

journal_title：PeerJ

authors： Simpson S,Edwards J,Emes RD,Cobb MA,Mongan NP,Rutland CS

更新日期：2015-03-26 00:00:00

abstract：BACKGROUND:Because etomidate induces prolonged adrenal suppression, even following a single bolus, its use as an infused anesthetic is limited. Our previous study indicated that a single administration of the novel etomidate analog methoxyethyletomidate hydrochloride (ET-26-HCl) shows little suppression of adrenocortic...

journal_title：PeerJ

authors： Jiang J,Wang B,Zhu Z,Yang J,Liu J,Zhang W

更新日期：2017-09-04 00:00:00

abstract：:Spatial genetic variation of river-dwelling freshwater fishes is typically affected by the historical and contemporary river landscape as well as life-history traits. Tropical river and stream landscapes have endured extended geological change, shaping the existing pattern of genetic diversity, but were not directly a...

journal_title：PeerJ

authors： Jaisuk C,Senanan W

更新日期：2018-03-07 00:00:00

abstract：Background:B-mode ultrasound is one of the most commonly used imaging techniques for evaluating thyroid nodules due to its noninvasive property and excellent performance in terms of discriminating between benign and malignant nodules. However, the accuracy of differential diagnosis strongly depends on the experience of...

journal_title：PeerJ

authors： Wang J,He X,Ma L,Li M,Sun L,Jiang J,Zhou Q

更新日期：2020-05-04 00:00:00

abstract：Background:Due to intensive sluice construction and other human disturbances, lakeshore vegetation has been destroyed and ecosystems greatly changed. Rhizospheric microbiota constitute a key part of a functioning rhizosphere ecosystem. Maintaining rhizosphere microbial diversity is a central, critical issue for sustain...

journal_title：PeerJ

authors： Zhang X,Wang H,Li Z,Xie J,Ni J

更新日期：2020-09-29 00:00:00

abstract：:Elucidating the molecular mechanism of helix-coil transitions of short peptides is a long-standing conundrum in physical chemistry. Although the helix-coil transitions of poly-glutamic acid (PGA) have been extensively studied, the molecular details of its unfolding process still remain unclear. We performed all-atom c...

journal_title：PeerJ

authors： Ogasawara N,Kasahara K,Iwai R,Takahashi T

更新日期：2018-05-15 00:00:00