Temporal and spatial strategies in an active place avoidance task on Carousel: a study of effects of stability of arena rotation speed in rats.

abstract：Background:Yunnanolepidoids constitute either the most basal consecutive segments or the most primitive clade of antiarchs, a highly diversified jawed vertebrate group from the Silurian and Early Devonian periods. Although the general morphology of yunnanolepidoids is well established, their endocranial features remain...

journal_title：PeerJ

authors： Wang Y,Zhu M

更新日期：2018-05-28 00:00:00

abstract：:Synaptic exocytosis requires the assembly of syntaxin 1A and SNAP-25 on the plasma membrane and synaptobrevin 2 (VAMP2) on the vesicular membrane to bridge the two opposite membranes. It is believed that the three SNARE proteins assemble in steps along the dynamic assembly pathway. The C-terminus of SNAP-25 is known t...

journal_title：PeerJ

authors： Lu B

更新日期：2015-06-30 00:00:00

abstract：:It is assumed that the sequencing of ribosomes better reflects the active microbial community than the sequencing of the ribosomal RNA encoding genes. Yet, many studies exploring microbial communities in various environments, ranging from the human gut to deep oceans, questioned the validity of this paradigm due to th...

journal_title：PeerJ

authors： Šťovíček A,Cohen-Chalamish S,Gillor O

更新日期：2019-10-25 00:00:00

abstract：BACKGROUND:Information on cardiovascular gene transcription is fragmented and far behind the present requirements of the systems biology field. To create a comprehensive source of data for cardiovascular gene regulation and to facilitate a deeper understanding of genomic data, the CardioTF database was constructed. The...

journal_title：PeerJ

authors： Zhen Y

更新日期：2016-08-23 00:00:00

abstract：BACKGROUND:Self-contained tests estimate and test the association between a phenotype and mean expression level in a gene set defined a priori. Many self-contained gene set analysis methods have been developed but the performance of these methods for phenotypes that are continuous rather than discrete and with multiple...

journal_title：PeerJ

authors： Walker JA

更新日期：2016-10-11 00:00:00

abstract：:Defensive traits exhibited by plants vary widely across populations. Heritable phenotypic differentiation is likely to be produced by genetic drift and spatially restricted gene flow between populations. However, spatially variable selection exerted by herbivores may also give rise to differences among populations. To...

journal_title：PeerJ

authors： Castillo G,Valverde PL,Cruz LL,Hernández-Cumplido J,Andraca-Gómez G,Fornoni J,Sandoval-Castellanos E,Olmedo-Vicente E,Flores-Ortiz CM,Núñez-Farfán J

更新日期：2015-11-26 00:00:00

abstract：:Avoidance behavior involves learning responses that prevent upcoming aversive events; these responses typically extinguish when the aversive events stop materializing. Stimuli that signal safety from aversive events can paradoxically inhibit extinction of avoidance behavior. In animals, males and females process safet...

journal_title：PeerJ

authors： Radell ML,Beck KD,Pang KC,Myers CE

更新日期：2015-07-14 00:00:00

abstract：:Reliable abundance estimates for species are fundamental in ecology, fisheries, and conservation. Consequently, predictive models able to provide reliable estimates for un- or poorly-surveyed locations would prove a valuable tool for management. Based on commonly used environmental and physical predictors, we develope...

journal_title：PeerJ

authors： Sequeira AMM,Mellin C,Lozano-Montes HM,Meeuwig JJ,Vanderklift MA,Haywood MDE,Babcock RC,Caley MJ

更新日期：2018-04-17 00:00:00

abstract：BACKGROUND:Aspergillus niger, along with many other lignocellulolytic fungi, has been widely used as a commercial workhorse for cellulase production. A fungal cellulase system generally includes three major classes of enzymes i.e., β-glucosidases, endoglucanases and cellobiohydrolases. Cellobiohydrolases (CBH) are vita...

journal_title：PeerJ

authors： Woon JS,Mackeen MM,Illias RM,Mahadi NM,Broughton WJ,Murad AMA,Abu Bakar FD

更新日期：2017-10-12 00:00:00

abstract：:We present a new supertree method that enables rapid estimation of a summary tree on the scale of millions of leaves. This supertree method summarizes a collection of input phylogenies and an input taxonomy. We introduce formal goals and criteria for such a supertree to satisfy in order to transparently and justifiabl...

journal_title：PeerJ

authors： Redelings BD,Holder MT

更新日期：2017-03-01 00:00:00

abstract：Background:The circadian clock not only participates in regulating various stages of plant growth, development and metabolism, but confers plant environmental adaptability to stress such as drought. Pseudo-Response Regulators (PRRs) are important component of the central oscillator (the core of circadian clock) and pla...

journal_title：PeerJ

authors： Wang J,Du Z,Huo X,Zhou J,Chen Y,Zhang J,Pan A,Wang X,Wang F,Zhang J

更新日期：2020-09-25 00:00:00

abstract：:RNA sequencing (RNA-Seq) enables the measurement and comparison of gene expression with isoform-level quantification. Differences in the effect of each isoform may make traditional methods, which aggregate isoforms, ineffective. Here, we introduce a variance component-based test that can jointly test multiple isoforms...

journal_title：PeerJ

authors： Yang S,Shao F,Duan W,Zhao Y,Chen F

更新日期：2017-09-08 00:00:00

abstract：Background:A key step in embryo implantation is the adhesion to and invasion of the endometrium by the blastocyst trophectoderm. The envelope proteins of HERV-W and -FRD (human endogenous retrovirus-W and -FRD), syncytin-1 and syncytin-2, are mainly distributed in the placenta, and play important roles in the developme...

journal_title：PeerJ

authors： Guo L,Gu F,Xu Y,Zhou C

更新日期：2020-11-17 00:00:00

abstract：:Almost all extant testudinids are highly associated with terrestrial habitats and the few tortoises with high affinity to aquatic environments are found within the genus Manouria. Manouria belongs to a clade which forms a sister taxon to all remaining tortoises and is suitable as a model for studying evolutionary tran...

journal_title：PeerJ

authors： Natchev N,Tzankov N,Werneburg I,Heiss E

更新日期：2015-08-11 00:00:00

abstract：:Although anthophilous Coleoptera are regarded to be unspecialised flower-visiting insects, monkey beetles (Scarabaeidae: Hopliini) represent one of the most important groups of pollinating insects in South Africa's floristic hotspot of the Greater Cape Region. South African monkey beetles are known to feed on floral t...

journal_title：PeerJ

authors： Karolyi F,Hansal T,Krenn HW,Colville JF

更新日期：2016-01-21 00:00:00

abstract：Background & Aims:Endothelial precursor cell (EPC) dysfunction is one of the risk factors for diabetes mellitus (DM) which results in delayed wound healing. Rosiglitazone (RSG) is a frequently prescribed oral glucose-lowering drug. Previous studies have shown the positive effects of RSG on ameliorating EPC dysfunction ...

journal_title：PeerJ

authors： Zhou G,Han X,Wu Z,Shi Q,Bao X

更新日期：2019-10-17 00:00:00

abstract：Background:Nurses are often the first to activate the chain of survival when a cardiorespiratory arrest happens. That is why it is crucial that they keep their knowledge and skills up-to-date and their attitudes to resuscitation are very important. The main aim of this study was to analyse whether the level of theoreti...

journal_title：PeerJ

authors： Tíscar-González V,Blanco-Blanco J,Gea-Sánchez M,Rodriguez Molinuevo A,Moreno-Casbas T

更新日期：2019-02-07 00:00:00

abstract：:One of the best ex situ conservation strategies for wild germplasm is in vitro conservation of genetic banks. The success of in vitro conservation relies heavily on the micropropagation or performance of the species of interest. In the context of global change, crop production challenges and climate change, we face a ...

journal_title：PeerJ

authors： Hernández-Terán A,Wegier A,Benítez M,Lira R,Sosa Fuentes TG,Escalante AE

更新日期：2019-06-10 00:00:00

abstract：:Meniscal tears are a common cause of stifle lameness in dogs. Use of autologous synoviocytes from the affected stifle is an attractive cell source for tissue engineering replacement fibrocartilage. However, the diseased state of these cells may impede in vitro fibrocartilage formation. Synoviocytes from 12 osteoarthri...

journal_title：PeerJ

authors： Warnock JJ,Bobe G,Duesterdieck-Zellmer KF

更新日期：2014-09-30 00:00:00

abstract：Background:Ecosystem engineers are species that transform habitats in ways that influence other species.While the impacts of many engineers have been well described, our understanding of how their impact varies along environmental gradients remains limited. Although disentangling the effects of gradients and engineers ...

journal_title：PeerJ

authors： Costa AN,Bruna EM,Vasconcelos HL

更新日期：2018-10-09 00:00:00

abstract：Background:Sprint performance is an essential skill to target within soccer, which can be likely achieved with a variety of methods, including different on-field training options. One such method could be heavy resisted sprint training. However, the effects of such overload on sprint performance and the related kinetic...

journal_title：PeerJ

authors： Lahti J,Huuhka T,Romero V,Bezodis I,Morin JB,Häkkinen K

更新日期：2020-12-15 00:00:00

abstract：:Construction of hydropower stations has been an important approach to meet China's increasing power demand, but the impact of construction of hydropower stations on river microbiota is not fully understood. To evaluate this, the microbial composition from 18 sampling sites in the downstream of Jinsha River of China, u...

journal_title：PeerJ

authors： Chen X,He D,Zhou L,Cao Y,Li Z

更新日期：2020-07-16 00:00:00

abstract：:In highly biodiverse systems, such as coral reefs, prey species are faced with predatory threats from numerous species. Recognition of predators can be innate, or learned, and can help increase the chance of survival. Research suggests that parental exposure to increased predatory threats can affect the development, b...

journal_title：PeerJ

authors： Atherton JA,McCormick MI

更新日期：2020-06-18 00:00:00

abstract：:The ε subunit from ATP synthases acts as an ATP sensor in the bacterial cell to prevent ATP hydrolysis and thus the waste of ATP under conditions of low ATP concentration. However, the ATP binding affinities from various bacterial organisms differ markedly, over several orders of magnitude. For example, the ATP syntha...

journal_title：PeerJ

authors： Krah A,Bond PJ

更新日期：2018-09-05 00:00:00

abstract：Background:DegS is a periplasmic serine protease that is considered to be the initiator of the σE stress response pathway, and this protein plays an important role in the regulation of the stress response in E. coli. However, knowledge of the biological function and global regulatory network of DegS in Vibrio cholerae ...

journal_title：PeerJ

authors： Huang J,Chen Y,Chen J,Liu C,Zhang T,Luo S,Huang M,Min X

更新日期：2019-10-23 00:00:00

abstract：:Ephemeral rivers act as linear oases in drylands providing key resources to people and wildlife. However, not much is known about these rivers' sensitivities to human activities. We investigated the landscape-level determinants of riparian tree dieback along the Swakop River, a dammed ephemeral river in Namibia, focus...

journal_title：PeerJ

authors： Douglas CM,Mulligan M,Harrison XA,Henschel JR,Pettorelli N,Cowlishaw G

更新日期：2016-10-27 00:00:00

abstract：:Histopathological images contain rich phenotypic descriptions of the molecular processes underlying disease progression. Convolutional neural networks, state-of-the-art image analysis techniques in computer vision, automatically learn representative features from such images which can be useful for disease diagnosis, ...

journal_title：PeerJ

authors： Lu L,Daigle BJ Jr

更新日期：2020-03-12 00:00:00

abstract：:Live trapping is a common tool used to assess demography of small mammals. However, live-trapping is often expensive and stressful to captured individuals. Thus, assessing the relative tradeoffs among study goals, project expenses, and animal well-being is necessary. Here, we evaluated how apparent bias and precision ...

journal_title：PeerJ

authors： Weldy MJ,Wilson TM,Lesmeister DB,Epps CW

更新日期：2019-10-03 00:00:00

abstract：:In this study, silver nanoparticles (NP) were synthesized by two methods: using an aqueous extract of Mentha spicata leaves and using citrate ions as stabilizing agent, and the cytotoxicity and anticancer activity of both NP were evaluated in vitro. The particles synthesized with the aqueous extract were spherical wit...

journal_title：PeerJ

authors： Torres-Martínez Y,Arredondo-Espinoza E,Puente C,González-Santiago O,Pineda-Aguilar N,Balderas-Rentería I,López I,Ramírez-Cabrera MA

更新日期：2019-12-09 00:00:00

abstract：Background:BRCA1 and BRCA2 genes are currently proven to be closely related to high lifetime risks of breast cancer. To date, the closely related genes to BRCA1/2 mutations in breast cancer remains to be fully elucidated. This study aims to identify the gene expression profiles and interaction networks influenced by BR...

journal_title：PeerJ

authors： Li Y,Zhou X,Liu J,Yin Y,Yuan X,Yang R,Wang Q,Ji J,He Q

更新日期：2020-01-21 00:00:00