Unfolding of α-helical 20-residue poly-glutamic acid analyzed by multiple runs of canonical molecular dynamics simulations.

abstract：:Background. Research addressing distinctions and similarities between people's malevolent character traits (i.e., the Dark Triad: Machiavellianism, narcissism, and psychopathy) has detected inconsistent linear associations to temperament traits. Additionally, these dark traits seem to have a common core expressed as u...

journal_title：PeerJ

authors： Garcia D,Rosenberg P

更新日期：2016-02-08 00:00:00

abstract：:Allium tenuissimum L. is a widely distributed perennial herbaceous species in temperate and desert steppes. Relative to other wild Allium species, it produces unique sweet flavors, more biomass in arid and cold environments, and has generated greater interest for crop production. Successful crop establishment, however...

journal_title：PeerJ

authors： Xiao H,Yang H,Monaco T,Song Q,Rong Y

更新日期：2020-04-07 00:00:00

abstract：:I used radio-telemetry to track the movements of Mangrove Cuckoos (Coccyzus minor) captured in southwest Florida. Relatively little is known about the natural history of Mangrove Cuckoos, and my goal was to provide an initial description of how individuals use space, with a focus on the size and placement of home rang...

journal_title：PeerJ

authors： Lloyd JD

更新日期：2017-06-30 00:00:00

abstract：Background:Bioactive peptides can prevent damage associated with oxidative stress in humans when consumed regularly. Recently, peptides have attracted immense interest because of their beneficial functional properties, safety and little or no side effects when used at high concentration. Most antioxidant peptides are s...

journal_title：PeerJ

authors： Sonklin C,Laohakunjit N,Kerdchoechuen O

更新日期：2018-07-27 00:00:00

abstract：:Background. The relative efficacy and safety of lacosamide as adjunctive therapy compared to other antiepileptic drugs has not been well established. Objective. To determine if lacosamide provides improved efficacy and safety, reduced length of hospital stay and improved quality of life compared with other anti-epilep...

journal_title：PeerJ

authors： Sawh SC,Newman JJ,Deshpande S,Jones PM

更新日期：2013-08-06 00:00:00

abstract：:The ability to accurately identify and label emotions in the self and others is crucial for successful social interactions and good mental health. In the current study we tested the longitudinal relationship between early language skills and recognition of facial and vocal emotion cues in a representative UK populatio...

journal_title：PeerJ

authors： Griffiths S,Goh SKY,Norbury CF,the SCALES team.

更新日期：2020-05-12 00:00:00

abstract：Background:The functional significance of ADAMs family members in the immune infiltration of pancreatic adenocarcinoma (PAAD) awaits elucidation. Methods:ADAMs family members with significant expression were identified among differentially expressed genes of PAAD based on The Cancer Genome Atlas (TCGA) database follow...

journal_title：PeerJ

authors： Qi B,Liu H,Dong Y,Shi X,Zhou Q,Zeng F,Bao N,Li Q,Yuan Y,Yao L,Xia S

更新日期：2020-09-30 00:00:00

abstract：:Pantoea stewartii subsp. stewartii is a bacterial phytopathogen that causes Stewart's wilt disease in corn. It uses quorum sensing to regulate expression of some genes involved in virulence in a cell density-dependent manner as the bacterial population grows from small numbers at the initial infection site in the leaf...

journal_title：PeerJ

authors： Packard H,Kernell Burke A,Jensen RV,Stevens AM

更新日期：2017-04-27 00:00:00

abstract：Objectives:The purpose of this study is to investigate the patterns of complementary and alternative medicine use and its association with time to conventional treatment. Design:A cross-sectional study design was designed. Setting and participants:The study was performed at the Chonburi Cancer Hospital, with chart re...

journal_title：PeerJ

authors： Chotipanich A,Sooksrisawat C,Jittiworapan B

更新日期：2019-06-14 00:00:00

abstract：:A feeding trial was conducted to assess the feasibility of supplementing taurine in soy-based diets for juvenile starry flounder Platichthys stellatus. The basal diet (Crude protein 66.5%, crude lipid 8.5%) was supplemented with 0 (control), 0.5%, 1.0%, 1.5%, 2.0% and 2.5% taurine to formulate six test diets. Each die...

journal_title：PeerJ

authors： Li P,Bu H,Li B,Sun Y,Wang M,Song Z

更新日期：2021-01-11 00:00:00

abstract：Background:The problem of access to medical information, particularly in low-income countries, has been under discussion for many years. Although a number of developments have occurred in the last decade (e.g., the open access (OA) movement and the website Sci-Hub), everyone agrees that these difficulties still persist...

journal_title：PeerJ

authors： Boudry C,Alvarez-Muñoz P,Arencibia-Jorge R,Ayena D,Brouwer NJ,Chaudhuri Z,Chawner B,Epee E,Erraïs K,Fotouhi A,Gharaibeh AM,Hassanein DH,Herwig-Carl MC,Howard K,Kaimbo Wa Kaimbo D,Laughrea PA,Lopez FA,Machin-Mastromatteo

更新日期：2019-10-30 00:00:00

abstract：Background:Methylenetetrahydrofolate reductase (MTHFR) is indispensable for the conversion of homocysteine (Hcy) to methionine. The single nucleotide polymorphism (SNP) of MTHFR gene (rs1801133, C667T) is correlated with decreased enzyme activity that eventually results in elevated plasma Hcy levels. Hyperhomocysteinem...

journal_title：PeerJ

authors： Yuan H,Fu M,Yang X,Huang K,Ren X

更新日期：2020-02-20 00:00:00

abstract：:The exploration of the evolution of RNA viruses has been aided recently by the discovery of copies of fragments or complete genomes of non-retroviral RNA viruses (Non-retroviral Endogenous RNA Viral Elements, or NERVEs) in many eukaryotic nuclear genomes. Among the most prominent NERVEs are partial copies of the RNA d...

journal_title：PeerJ

authors： Bruenn JA,Warner BE,Yerramsetty P

更新日期：2015-04-09 00:00:00

abstract：Background:Development of incisional complications following ventral median celiotomy might depend on suture pattern for skin closure. Methods:In this prospective study, 21 healthy male horses underwent celiotomy. Skin closure was either performed via a continuous percutaneous pattern (CO group; 5 warmbloods/5 ponies)...

journal_title：PeerJ

authors： Scharner D,Gittel C,Winter K,Blaue D,Schedlbauer C,Vervuert I,Brehm W

更新日期：2018-11-09 00:00:00

abstract：:Bcl-2 (B-cell lymphoma 2) protein is localized in the outer membrane of mitochondria, where it plays an important role in promoting cellular survival and inhibiting the actions of pro-apoptotic proteins. PRDM10 is a member of the PR/SET family of epigenetic regulators and may play a role in development and cell differ...

journal_title：PeerJ

authors： Chen N,Hu T,Gui Y,Gao J,Li Z,Huang S

更新日期：2019-05-15 00:00:00

abstract：:A conglomerate bed from the Tournaisian Ballagan Formation of Scotland preserves a rich array of vertebrate and other nonmarine fossils providing an insight into the wider ecosystem and paleoenvironment that existed during this pivotal stage of Earth history. It challenges hypotheses of a long-lasting post-extinction ...

journal_title：PeerJ

authors： Clack JA,Bennett CE,Davies SJ,Scott AC,Sherwin JE,Smithson TR

更新日期：2019-01-03 00:00:00

abstract：:Physical exercise is linked to individuals whose affect profiles are invariably positive and it induces anti-apoptotic and anti-excitotoxic effects, buttressing blood-brain barrier intactness in both healthy individuals and those suffering from disorders accompanying overweight and obesity. In this regard, exercise of...

journal_title：PeerJ

authors： Garcia D,Archer T

更新日期：2014-12-16 00:00:00

abstract：:The term autobiographical self has been used to refer to a mental state that permits reflection on self-identity and personality and the answer to related questions (Damasio, 1998). It requires the retrieval and integrated assembly of memories of facts and events that define an individual's biography. The neural mecha...

journal_title：PeerJ

authors： Araujo HF,Kaplan J,Damasio H,Damasio A

更新日期：2014-07-22 00:00:00

abstract：OBJECTIVES:Compare the immediate effects of a Neurodynamic Mobilization (NM) treatment or foam roller (FR) treatment after DOMS. DESIGN:Double blind randomised clinical trial. SETTING:The participants performed 100 drop jumps (5 sets of 20 repetitions, separated by 2 min rests) from a 0.5-m high box in a University b...

journal_title：PeerJ

authors： Romero-Moraleda B,La Touche R,Lerma-Lara S,Ferrer-Peña R,Paredes V,Peinado AB,Muñoz-García D

更新日期：2017-10-13 00:00:00

abstract：:Some plants popularly employed for the treatment of peptic ulcers have proved to be attractive sources of new drugs. Despite extensive research, the pharmacological and toxicological potentials of these plants are not fully understood. In this context, the aim of this work was to analyze the multielemental composition...

journal_title：PeerJ

authors： Vieira LD,da Silva KT,Giarola RS,Inocente GF,Kushima H,Hiruma Lima CA,Hormaza JM

更新日期：2018-09-12 00:00:00

abstract：:Substantial evidence has shown that most exogenous substances are metabolized by multiple cytochrome P450 (P450) enzymes instead of by merely one P450 isoform. Thus, multi-P450 inhibition leads to greater drug-drug interaction risk than specific P450 inhibition. Herein, we innovatively established an artificial neural...

journal_title：PeerJ

authors： Li Z,Li Y,Sun L,Tang Y,Liu L,Zhu W

更新日期：2015-12-21 00:00:00

abstract：Background:Overweight (OW) is considered a risk for various metabolic diseases. However, its effects as a mechanism that alters the metabolite profiles remain unclear. The purpose of this study is to investigate the effects that OW has on the lipid and metabolite profiles in young adults. Methods:The serum metabolite ...

journal_title：PeerJ

authors： Pasanta D,Chancharunee S,Tungjai M,Kim HJ,Kothan S

更新日期：2019-06-20 00:00:00

abstract：INTRODUCTION:Early detection of social anxiety and loneliness might be useful to prevent substantial impairment in personal relationships. Understanding the way people use smartphones can be beneficial for implementing an early detection of social anxiety and loneliness. This paper examines different types of smartphon...

journal_title：PeerJ

authors： Gao Y,Li A,Zhu T,Liu X,Liu X

更新日期：2016-07-12 00:00:00

abstract：Background:Riparian corridors can affect nutrient, organic matter, and sediment transport, all of which shape water quality in streams and connected downstream waters. When functioning riparian corridors remain intact, they provide highly valued water quality ecosystem services. However, in rapidly urbanizing watershed...

journal_title：PeerJ

authors： Atkinson SF,Lake MC

更新日期：2020-02-04 00:00:00

abstract：Background:Electrochemical signals play an important role in cell communication and behavior. Electrically charged ions transported across cell membranes maintain an electrochemical imbalance that gives rise to bioelectric signaling, called membrane potential or Vmem. Vmem plays a key role in numerous inter- and intrac...

journal_title：PeerJ

authors： Bhavsar MB,Cato G,Hauschild A,Leppik L,Costa Oliveira KM,Eischen-Loges MJ,Barker JH

更新日期：2019-02-08 00:00:00

abstract：Background:Selective serotonin reuptake inhibitors (SSRIs) are among the most widely prescribed class of drugs in the practice of psychiatry. Cytochrome P450 (CYP) 2C19 and CYP2D6 are established as clinically relevant drug metabolizing enzymes (DMEs) that influence the pharmacokinetics of SSRIs and may either be group...

journal_title：PeerJ

authors： Eugene AR

更新日期：2019-10-09 00:00:00

abstract：Background:It was well known that age has an impact on word processing (word frequency or predictability) in terms of fixating time during reading. However, little is known about whether or not age modulates these impacts on saccade behaviors in Chinese reading (i.e., length of incoming/outgoing saccades for a target w...

journal_title：PeerJ

authors： Liu Z,Tong W,Su Y

更新日期：2020-04-01 00:00:00

abstract：:The mature spermatozoa of Stephanostomum murielae and Stephanostomoides tenuis are described by transmission electron microscopy. They present several ultrastructural features previously reported in other digeneans. Their spermatozoa possess two axonemes of different length showing the 9 + '1' trepaxonematan pattern, ...

journal_title：PeerJ

authors： Bakhoum AJ,Quilichini Y,Justine JL,Bray RA,Bâ CT,Marchand B

更新日期：2015-02-12 00:00:00

abstract：Background:The Chinese Natural Forest Protection program has been conducted nationwide and has achieved resounding success. However, timber importation has increased; therefore, producing more domestic timber is critical to meet the demand for raw materials. Fertilization is one of the most effective silviculture pract...

journal_title：PeerJ

authors： Hou L,Dong Z,Yang Y,Zhang D,Zhang S,Zhang S

更新日期：2018-04-13 00:00:00

abstract：Background:Forest ecosystems are considered among the largest terrestrial carbon sinks. The dynamics of forest carbon depend on where the carbon is stored and its responses to environmental factors, as well as the physiology of the trees. Thus, threatened forest regions with high biodiversity have great scientific impo...

journal_title：PeerJ

authors： González-Cásares M,Pompa-García M,Venegas-González A,Domínguez-Calleros P,Hernández-Díaz J,Carrillo-Parra A,González-Tagle M

更新日期：2019-06-11 00:00:00