Transcriptional regulation of Bcl-2 gene by the PR/SET domain family member PRDM10.

abstract：:Obesity is demonstrated to be a risk factor in the development of cancers of various organs, such as colon, prostate, pancreas and so on. Leptine (LEP) is the most renowned of the adipokines. As a hormone, it mediates its effect through leptin receptor (LEPR), which is widely expressed in various tissues including col...

journal_title：PeerJ

authors： Al-Shibli SM,Harun N,Ashour AE,Mohd Kasmuri MHB,Mizan S

更新日期：2019-10-02 00:00:00

abstract：:Seabed mapping can quantify the extent of benthic habitats that comprise marine ecosystems, and assess the impact of fisheries on an ecosystem. In this study, the distribution of seabed habitats in a proposed no-take Marine Reserve along the northeast coast of Great Barrier Island, New Zealand, was mapped using underw...

journal_title：PeerJ

authors： Lee ST,Kelly M,Langlois TJ,Costello MJ

更新日期：2015-12-10 00:00:00

abstract：:Parallelism is important because it reveals how inherently stochastic adaptation is. Even as we come to better understand evolutionary forces, stochasticity limits how well we can predict evolutionary outcomes. Here we sought to quantify parallelism and some of its underlying causes by adapting a bacteriophage (ID11) ...

journal_title：PeerJ

authors： Miller CR,Nagel AC,Scott L,Settles M,Joyce P,Wichman HA

更新日期：2016-07-19 00:00:00

abstract：Background:Hair follicles in cashmere goats are divided into primary and secondary hair follicles (HFs). HF development, which determines the morphological structure, is regulated by a large number of vital genes; however, the key functional genes and their interaction networks are still unclear. Although the vitamin D...

journal_title：PeerJ

authors： Gao Y,Jin M,Niu Y,Yan H,Zhou G,Chen Y

更新日期：2019-07-03 00:00:00

abstract：:Background. Caesarean birth rates in North America continue to rise, in the absence of benefit for mothers and babies. One reason may be that hospitalized labouring women spend most of their labours in recumbent or semi-recumbent positions. Although hands-and-knees position has theoretical advantages, efforts to encou...

journal_title：PeerJ

authors： Hodnett ED,Stremler R,Halpern SH,Weston J,Windrim R

更新日期：2013-02-12 00:00:00

abstract：Background:Circadian genes have been suggested to play an important role in lung pathology. However, it remains unknown whether polymorphisms of these genes are associated with chronic obstructive pulmonary disease (COPD). Here, we aimed to investigate the association of circadian genes polymorphisms with COPD in a cas...

journal_title：PeerJ

authors： Chen G,Zhang J,Zhang L,Xiong X,Yu D,Zhang Y

更新日期：2020-08-27 00:00:00

abstract：:Xiphosurans are aquatic chelicerates with a fossil record extending into the Early Ordovician and known from a total of 88 described species, four of which are extant. Known for their apparent morphological conservatism, for which they have gained notoriety as supposed 'living fossils', recent analyses have demonstrat...

journal_title：PeerJ

authors： Lamsdell JC

更新日期：2020-12-04 00:00:00

abstract：BACKGROUND:Algae encompass a wide array of photosynthetic organisms that are ubiquitously distributed in aquatic and terrestrial habitats. Algal species often bloom in aquatic ecosystems, providing a significant autochthonous carbon input to the deeper anoxic layers in stratified water bodies. In addition, various alga...

journal_title：PeerJ

authors： Morrison JM,Murphy CL,Baker K,Zamor RM,Nikolai SJ,Wilder S,Elshahed MS,Youssef NH

更新日期：2017-01-10 00:00:00

abstract：Purpose:To explore whether unilateral relapse of Bechet's disease-associated uveitis (BDU) causes differences in the tear proteome between the diseased and the contralateral quiescent eye and potential tear biomarkers for uveitis recurrence and disease monitoring. Method:To minimize interindividual variations, bilater...

journal_title：PeerJ

authors： Liang A,Qin W,Zhang M,Gao F,Zhao C,Gao Y

更新日期：2020-06-19 00:00:00

abstract：:Mechanisms generating and maintaining biodiversity at regional scales may be evaluated by quantifying β-diversity along environmental gradients. Differences in assemblages result in biotic complementarities and redundancies among sites, which may be quantified through multi-dimensional approaches incorporating taxonom...

journal_title：PeerJ

authors： de Fraga R,Ferrão M,Stow AJ,Magnusson WE,Lima AP

更新日期：2018-09-24 00:00:00

abstract：Background:The fall webworm, Hyphantria cunea Drury (Lepidoptera: Erebidae), is a widespread invasive species. It is native to North America, ranging from southern Canada to northern Mexico. During and after the 1940s, this pest was accidentally introduced in many parts of Europe and Asia. It has now spread to more tha...

journal_title：PeerJ

authors： Mikami OK,Takamatsu M,Yarita R

更新日期：2020-06-02 00:00:00

abstract：:The most intense commercial harvest of marine aquarium species in North America occurs in the coastal waters surrounding Florida, yet very often little information exists on the life histories, population dynamics, or reproductive characteristics of these organisms. The peppermint shrimp Lysmata boggessi is one such s...

journal_title：PeerJ

authors： Dickson MD,Behringer DC,Baeza JA

更新日期：2020-01-23 00:00:00

abstract：:A range of diseases is associated with amyloid fibril formation. Despite different proteins being responsible for each disease, all of them share similar features including beta-sheet-rich secondary structure and fibril-like protein aggregates. A number of proteins can form amyloid-like fibrils in vitro, resembling st...

journal_title：PeerJ

authors： Šneideris T,Baranauskienė L,Cannon JG,Rutkienė R,Meškys R,Smirnovas V

更新日期：2015-09-24 00:00:00

abstract：:Organic fertilizer application could have an impact on the nitrogen cycle mediated by microorganisms in arable soils. However, the dynamics of soil ammonia oxidizers and denitrifiers in response to compost addition are less understood. In this study, we examined the effect of four compost application rates (0, 11.25, ...

journal_title：PeerJ

authors： Yang Z,Guan Y,Bello A,Wu Y,Ding J,Wang L,Ren Y,Chen G,Yang W

更新日期：2020-04-21 00:00:00

abstract：:In the Balearic Islands, different trammel net designs have been adopted to promote fisheries sustainability and reduce discards. Here, we compare the catch performance of three trammel net designs targeting the spiny lobster Palinurus elephas in terms of biomass, species composition and revenue from commercial catche...

journal_title：PeerJ

authors： Catanese G,Hinz H,Gil MDM,Palmer M,Breen M,Mira A,Pastor E,Grau A,Campos-Candela A,Koleva E,Grau AM,Morales-Nin B

更新日期：2018-05-17 00:00:00

abstract：:Development of mobile sensors brings new opportunities to medical research. In particular, mobile electroencephalography (EEG) devices can be potentially used in low cost screening for epilepsy and other neurological and psychiatric disorders. The necessary condition for such applications is thoughtful validation in t...

journal_title：PeerJ

authors： Kutafina E,Brenner A,Titgemeyer Y,Surges R,Jonas S

更新日期：2020-05-01 00:00:00

abstract：:The origin of recent parallel outbreaks of the high pathogenicity H5N8 avian flu virus in Europe and in Japan can be traced to a single source population, which has most likely been spread by migratory birds. By using Bayesian coalescent methods to analyze the DNA sequences of the virus to find the times for divergenc...

journal_title：PeerJ

authors： Dalby AR,Iqbal M

更新日期：2015-04-30 00:00:00

abstract：:The maximum likelihood estimation (MLE) method, typically used for polytomous logistic regression, is prone to bias due to both misclassification in outcome and contamination in the design matrix. Hence, robust estimators are needed. In this study, we propose such a method for nominal response data with continuous cov...

journal_title：PeerJ

authors： Wang X

更新日期：2014-07-01 00:00:00

abstract：Background:Patellofemoral pain (PFP) is often reported as a diffuse pain at the front of the knee during knee-loading activities. A patient's description of pain location and distribution is commonly drawn on paper by clinicians, which is difficult to quantify, report and compare within and between patients. One way of...

journal_title：PeerJ

authors： Matthews M,Rathleff MS,Vicenzino B,Boudreau SA

更新日期：2018-03-08 00:00:00

abstract：:Climatic fluctuations during the Quaternary significantly affect many species in their intraspecific divergence and population structure across northwest China. In order to investigate the impact of climate change on herbaceous plants, we studied Panzerina lanata (Lamiaceae), a widely distributed species. Sequences of...

journal_title：PeerJ

authors： Zhao Y,Zhang H,Pan B,Zhang M

更新日期：2019-01-24 00:00:00

abstract：Background:SHOX mutations have previously been described as causes of Léri-Weill dyschondrosteosis (LWD), Langer mesomelic dysplasia (LMD), and idiopathic short stature. The loss of X chromosome-Turner syndrome or mosaic 45,X/46,XX or 46,XY-also leads to the heterozygous loss of SHOX in patients with short stature only...

journal_title：PeerJ

authors： Capkova P,Capkova Z,Rohon P,Adamová K,Zapletalova J

更新日期：2020-11-17 00:00:00

abstract：:Seymouria is the best known of the seymouriamorphs, a group of Permo-Carboniferous reptiliomorphs with both terrestrial and aquatic taxa. The majority of research on Seymouria has focused on cranial anatomy, with few detailed descriptions or illustrations of the postcrania. We utilized neutron computed tomography (nCT...

journal_title：PeerJ

authors： Bazzana KD,Gee BM,Bevitt JJ,Reisz RR

更新日期：2020-03-10 00:00:00

abstract：:This study provides information on biological (gonadosomatic index), commercial quality (condition index and meat yield) and biochemical aspects (proximate composition, fatty acids) of the soft tissues of Flexopecten glaber reared in suspended cages in the Ionian Sea. The results showed that condition index (CI) and m...

journal_title：PeerJ

authors： Prato E,Biandolino F,Parlapiano I,Papa L,Denti G,Fanelli G

更新日期：2019-01-21 00:00:00

abstract：:We revise the genus Conostigmus Dahlbom 1858 occurring in Madagascar, based on data from more specimens than were examined for the latest world revision of the genus. Our results yield new information about intraspecific variability and the nature of the atypical latitudinal diversity gradient (LDG) observed in Ceraph...

journal_title：PeerJ

authors： Mikó I,Trietsch C,Sandall EL,Yoder MJ,Hines H,Deans AR

更新日期：2016-12-13 00:00:00

abstract：:Pseudoterranovosis is a well-known human disease caused by anisakid larvae belonging to the genus Pseudoterranova. Human infection occurs after consuming infected fish. Hence the presence of Pseudoterranova larvae in the flesh of the fish can cause serious losses and problems for the seafood, fishing and fisheries ind...

journal_title：PeerJ

authors： Shamsi S,Suthar J

更新日期：2016-03-15 00:00:00

abstract：:Purple Broccoli (Brassica oleracea L. var italica) attracts growing attention as a functional food. Its purple coloration is due to high anthocyanin amounts. Light represents a critical parameter affecting anthocyanins biosynthesis. In this study, 'Purple Broccoli', a light-responding pigmentation cultivar, was assess...

journal_title：PeerJ

authors： Liu C,Yao X,Li G,Huang L,Xie Z

更新日期：2020-05-05 00:00:00

abstract：:We describe Atrimitra isolata sp. n. (Gastropoda: Mitridae), collected on the summit of seamounts (~200 m water depth) in the vicinity of Desventuradas Islands, Chile insular territory. Additionally, we provide some insight into the habitat of this new species based on underwater imagery taken with a remotely operated...

journal_title：PeerJ

authors： Sellanes J,Salisbury RA,Tapia JM,Asorey CM

更新日期：2019-12-20 00:00:00

abstract：:Harmine is the β-carboline alkaloid with the highest concentration in the psychotropic plant decoction Ayahuasca. In rodents, classical antidepressants reverse the symptoms of depression by stimulating neuronal proliferation. It has been shown that Ayahuasca presents antidepressant effects in patients with depressive ...

journal_title：PeerJ

authors： Dakic V,Maciel RM,Drummond H,Nascimento JM,Trindade P,Rehen SK

更新日期：2016-12-06 00:00:00

abstract：Background:The Mountain Pygmy-possum (Burramys parvus) is a critically endangered marsupial, endemic to alpine regions of southern Australia. We investigated the diet of a recently discovered population of the possum in northern Kosciuszko National Park, NSW, Australia. This new population occurs at elevations well bel...

journal_title：PeerJ

authors： Hawke T,Bates H,Hand S,Archer M,Broome L

更新日期：2019-01-24 00:00:00

abstract：:Coastal birds are critical ecosystem constituents on sandy shores, yet are threatened by depressed reproductive success resulting from direct and indirect anthropogenic and natural pressures. Few studies examine clutch fate across the wide range of environments experienced by birds; instead, most focus at the small si...

journal_title：PeerJ

authors： Maslo B,Schlacher TA,Weston MA,Huijbers CM,Anderson C,Gilby BL,Olds AD,Connolly RM,Schoeman DS

更新日期：2016-09-13 00:00:00