Association analysis between chronic obstructive pulmonary disease and polymorphisms in circadian genes.

abstract：Objective:The N-methyl-D-aspartate subtype glutamate receptor antagonist ketamine has rapid antidepressant and antisuicidal effects in treating treatment-resistant bipolar depression (TRBD). The neurocognitive effects of repeated ketamine infusions in TRBD are not known. Methods:Six intravenous infusions of ketamine (...

journal_title：PeerJ

authors： Zheng W,Zhou YL,Wang CY,Lan XF,Zhang B,Yang MZ,Nie S,Ning YP

更新日期：2020-11-03 00:00:00

abstract：Purpose:Yes associated protein 1 (YAP1), which is a standout amongst the most essential effectors of the Hippo pathway, assumes a vital part in a few kinds of cancer. However, whether YAP1 is an oncogene in CRC (colorectal cancer) remains controversial, and the association between the subcellular localization of YAP1 a...

journal_title：PeerJ

authors： Dong T,Yuan Y,Xiang X,Sang S,Shen H,Wang L,Yang C,Li F,Li H,Zheng S

更新日期：2020-11-19 00:00:00

abstract：:In functional genomics experiments, researchers often select genes to follow-up or validate from a long list of differentially expressed genes. Typically, sharp thresholds are used to bin genes into groups such as significant/non-significant or fold change above/below a cut-off value, and ad hoc criteria are also used...

journal_title：PeerJ

authors： Lazic SE

更新日期：2015-11-26 00:00:00

abstract：:In this paper, we map the distribution of scale-rayed wrasse Acantholabrus palloni in eastern Skagerrak based on a combination of verified and personally communicated angling records. Long thought to be occasional vagrants outside its known range in the eastern Atlantic Ocean and Mediterranean Sea, we ask if this rare...

journal_title：PeerJ

authors： Näslund J,Lundgren M

更新日期：2018-11-06 00:00:00

abstract：:The goal of this study was to assess the diagnostic accuracy of acute phase proteins and proinflammatory cytokines in sheep with pneumonic pasteurellosis. Blood samples were collected from 56 sheep (36 naturally infected with Pasteurella multocida and 20 healthy controls) belonging to one farm in Eastern region, Saudi...

journal_title：PeerJ

authors： El-Deeb WM,Elmoslemany AM

更新日期：2016-07-19 00:00:00

abstract：Background:The fecal microbiota from obese individuals can induce obesity in animal models. In addition, studies in humans, animal models and dogs have revealed that the fecal microbiota of subjects with obesity is different from that of lean subjects and changes after weight loss. However, the impact of weight loss on...

journal_title：PeerJ

authors： Bermudez Sanchez S,Pilla R,Sarawichitr B,Gramenzi A,Marsilio F,Steiner JM,Lidbury JA,Woods GRT,German AJ,Suchodolski JS

更新日期：2020-10-05 00:00:00

abstract：:Wing pigmentation in Calopteryx damselflies, caused by the deposition of melanin, is energetically expensive to produce and enhances predation risk. However, patterns of melanisation are used in species identification, greater pigmentation is an accurate signal of male immune function in at least some species, and the...

journal_title：PeerJ

authors： Hassall C

更新日期：2014-06-10 00:00:00

abstract：:The Pomacentridae (damselfish) and Apogonidae (cardinalfish) are among the most common fish families on coral reefs and in the aquarium trade. Members of both families undergo a pelagic larvae phase prior to settlement on the reef, where adults play key roles in benthic habitat structuring and trophic interactions. Fi...

journal_title：PeerJ

authors： Parris DJ,Brooker RM,Morgan MA,Dixson DL,Stewart FJ

更新日期：2016-08-31 00:00:00

abstract：:Divergences between agricultural management can result in different types of biological interactions between plants and microorganisms, which may affect food quality and productivity. Conventional practices are well-established in the agroindustry as very efficient and lucrative; however, the increasing demand for sus...

journal_title：PeerJ

authors： Carvalho CR,Dias AC,Homma SK,Cardoso EJ

更新日期：2020-06-02 00:00:00

abstract：Background:Introduced predators at seabird colonies and parasites may have lethal and/or sub-lethal consequences for bird populations. We assessed the potential sub-lethal negative effects of these stressors in a native seabird listed as vulnerable in its south-eastern pacific distribution. This study was conducted in ...

journal_title：PeerJ

authors： Luna N,Varela AI,Luna-Jorquera G,Brokordt K

更新日期：2020-07-08 00:00:00

abstract：:The rapid development of China's textile industry (TI) has led to severe water environmental stress. Water environmental stress of China's TI mainly comes from large quantities of discharged wastewater and chemical oxygen demand (COD). The sustainable development of the TI is realized to achieve the decoupling between...

journal_title：PeerJ

authors： Li Y,Shen J,Lu L,Luo Y,Wang L,Shen M

更新日期：2018-06-29 00:00:00

abstract：:Bighead, silver, and grass carps are invasive in the waterways of central North America, and grass carp reproduction in tributaries of the Great Lakes has now been documented. Questions about recruitment potential motivate a need for accurate models of egg and larval dispersal. Quantitative data on swimming behaviors ...

journal_title：PeerJ

authors： George AE,Garcia T,Stahlschmidt BH,Chapman DC

更新日期：2018-11-02 00:00:00

abstract：:The effects of age on performance of life-history traits are diverse, but a common outcome is senescence, an irreversible deterioration of physical and physiological capabilities of older individuals. Immune response is potentially bound to senescence. However, little is known about immune response ageing in amphibian...

journal_title：PeerJ

authors： Zamora-Camacho FJ,Comas M

更新日期：2018-12-20 00:00:00

abstract：Background:The diagnosis of congenital heart defects is challenging, especially for what concerns conotruncal anomalies. Indeed, although the screening techniques of fetal cardiac anomalies have greatly improved, the detection rate of conotruncal anomalies still remains low due to the fact that they are associated with...

journal_title：PeerJ

authors： Dell'Oro S,Verderio M,Incerti M,Mastrolia SA,Cozzolino S,Vergani P

更新日期：2018-04-06 00:00:00

abstract：:Female adders (Vipera berus) are "capital breeders" that exhibit delayed maturity and intermittent reproductive frequency. We studied the attainment of sexual maturity, the initiation of annual breeding in mature females, the energy and mortality costs associated with breeding, the length of the reproductive cycle and...

journal_title：PeerJ

authors： Bauwens D,Claus K

更新日期：2019-05-09 00:00:00

abstract：:Bird communities in lowland Neotropical forests exhibit temporal and spatial variation in species composition and abundance at multiple scales. Detecting and explaining such variation requires adequate methods for sampling those bird communities but counting birds in highly diverse lowland forests of the Neotropics ca...

journal_title：PeerJ

authors： Blake JG

更新日期：2021-01-13 00:00:00

abstract：:The aim of this study was to analyze the influence of smoking habits and other possibly relevant factors on dental implant survival. The study population included all patients who underwent dental implants between the years 1999 and 2008 at a large military dental clinic and were examined in the periodic medical exami...

journal_title：PeerJ

authors： Twito D,Sade P

更新日期：2014-09-02 00:00:00

abstract：:Background. Low molecular weight heparin (LMWH) is an effective anti-coagulant for thrombotic events. However, due to its predominant renal clearance, there are concerns that it might be associated with increased bleeding in patients with renal disease. Objectives. We systematically evaluated the efficacy and safety o...

journal_title：PeerJ

authors： Palamaner Subash Shantha G,Kumar AA,Sethi M,Khanna RC,Pancholy SB

更新日期：2015-03-10 00:00:00

abstract：:In this study, four experimental assays were conducted to evaluate the use of a new silver nanoparticle formulation named Argovit-4, which was prepared with slight modifications to enhance its biological activity against white spot syndrome virus (WSSV) in shrimp culture. The goals of these assays were to (1) determin...

journal_title：PeerJ

authors： Romo-Quiñonez CR,Álvarez-Sánchez AR,Álvarez-Ruiz P,Chávez-Sánchez MC,Bogdanchikova N,Pestryakov A,Mejia-Ruiz CH

更新日期：2020-02-27 00:00:00

abstract：:The exoskeleton is an important source of characters for the taxonomy of Hydroidolina. It originates as epidermal secretions and, among other functions, protects the coenosarc of the polypoid stage. However, comparative studies on the exoskeletal tissue origin, development, chemical, and structural characteristics, as...

journal_title：PeerJ

authors： Mendoza-Becerril MA,Marian JE,Migotto AE,Marques AC

更新日期：2017-02-16 00:00:00

abstract：:In recent years, a massive mortality event has killed millions of sea stars, of many different species, along the Pacific coast of North America. This disease event, known as 'sea star wasting disease' (SSWD), is linked to viral infection. In one affected sea star (Pisaster ochraceus), previous work had identified tha...

journal_title：PeerJ

authors： Wares JP,Schiebelhut LM

更新日期：2016-03-29 00:00:00

abstract：BACKGROUND:Digital medicine and smartphone-enabled health technologies provide a novel source of human health and human biology data. However, in part due to its intricacies, few methods have been established to analyze and interpret data in this domain. We previously conducted a six-month interventional trial examinin...

journal_title：PeerJ

authors： Gollamudi SS,Topol EJ,Wineinger NE

更新日期：2016-08-02 00:00:00

abstract：:Urmia Lake, the largest natural habitat of the brine shrimp Artemia urmiana, has progressively desiccated over the last two decades, resulting in a loss of 80% of its surface area and producing thousands of hectares of arid salty land. This ecological crisis has seriously affected the lake's native biodiversity. Artem...

journal_title：PeerJ

authors： Asem A,Eimanifar A,van Stappen G,Sun SC

更新日期：2019-07-02 00:00:00

abstract：Background:Overweight (OW) is considered a risk for various metabolic diseases. However, its effects as a mechanism that alters the metabolite profiles remain unclear. The purpose of this study is to investigate the effects that OW has on the lipid and metabolite profiles in young adults. Methods:The serum metabolite ...

journal_title：PeerJ

authors： Pasanta D,Chancharunee S,Tungjai M,Kim HJ,Kothan S

更新日期：2019-06-20 00:00:00

abstract：:Despite the local and global importance of forests, deforestation is driven by various socio-economic and biophysical factors continues in many countries. In Nepal, in response to massive deforestation, the community forestry program has been implemented to reduce deforestation and support livelihoods. After four deca...

journal_title：PeerJ

authors： Shrestha S,Shrestha UB,Bawa K

更新日期：2018-05-29 00:00:00

abstract：Background:Panulirus argus is an ecologically relevant species in shallow water hard-bottom environments and coral reefs and target of the most lucrative fishery in the greater Caribbean region. Methods:This study reports, for the first time, the genome size and nuclear repetitive elements, including the 45S ribosomal...

journal_title：PeerJ

authors： Baeza JA

更新日期：2020-12-17 00:00:00

abstract：Background:Pandi's mushroom-tongue salamander (Bolitoglossa pandi) is one of the threatened amphibians in South America, as well as a flagship species for the Colombian conservation agenda. This species is endemic to the Andean cloud forests of the western slope of the Cordillera Oriental of Colombia, occurring only in...

journal_title：PeerJ

authors： Angarita-Sierra T,Bonilla-Gómez MA,Sánchez DA,Acosta-Galvis AR,Medina-Ovalle H,Solano-Moreno A,Ulloa-Rengifo S,Guevara-Guevara D,Torres-Ramirez JJ,Curaca-Fierro S,Cabrera-Amaya DM,Infante-Betancour JA,Londoño-Montaño LF,Albarán

更新日期：2020-09-24 00:00:00

abstract：:Previous studies of population genetic structure in Dissostichus eleginoides have shown that oceanographic and geographic discontinuities drive in this species population differentiation. Studies have focused on the genetics of D. eleginoides in the Southern Ocean; however, there is little knowledge of their genetic v...

journal_title：PeerJ

authors： Canales-Aguirre CB,Ferrada-Fuentes S,Galleguillos R,Oyarzun FX,Hernández CE

更新日期：2018-01-16 00:00:00

abstract：:Background. There has been a continual increase in injury rates in cricket, with hamstring strain injuries (HSIs) being the most prominent. Eccentric knee flexor weakness and bilateral asymmetries are major modifiable risk factors for future HSIs. However, there is a lack of data relating to eccentric hamstring streng...

journal_title：PeerJ

authors： Chalker WJ,Shield AJ,Opar DA,Keogh JW

更新日期：2016-02-18 00:00:00

abstract：:We documented significantly increasing trends in atmospheric loading of ammonium (NH4) and nitrate/nitrite (NO2/3) and decreasing trends in total phosphorus (P) and sulfate (SO4) to Flathead Lake, Montana, from 1985 to 2004. Atmospheric loading of NO2/3 and NH4 increased by 48 and 198% and total P and SO4 decreased by...

journal_title：PeerJ

authors： Ellis BK,Craft JA,Stanford JA

更新日期：2015-03-19 00:00:00