High cytoplasmic YAP1 expression predicts a poor prognosis in patients with colorectal cancer.

abstract：Background:Laminitis is a common equine disease characterized by foot pain, and is commonly diagnosed using a five-grade Obel system developed in 1948 using sepsis-related cases. However, endocrinopathic laminitis is now the most common form of the disease and clinical signs may be mild, or spread across two Obel grade...

journal_title：PeerJ

authors： Meier A,de Laat M,Pollitt C,Walsh D,McGree J,Reiche DB,von Salis-Soglio M,Wells-Smith L,Mengeler U,Mesa Salas D,Droegemueller S,Sillence MN

更新日期：2019-06-07 00:00:00

abstract：:Background. Just as for most other tortoise species, the once common Chaco tortoise, Chelonoidis chilensis (Testudinidae), is under constant threat across it distribution in Argentina, Bolivia and Paraguay. Despite initial qualitative description of the species distribution and further individual reports of new locati...

journal_title：PeerJ

authors： Ruete A,Leynaud GC

更新日期：2015-10-01 00:00:00

abstract：:Mega-journals are a new kind of scholarly journal made possible by electronic publishing. They are open access (OA) and funded by charges, which authors pay for the publishing services. What distinguishes mega-journals from other OA journals is, in particular, a peer review focusing only on scientific trustworthiness....

journal_title：PeerJ

authors： Björk BC

更新日期：2018-02-09 00:00:00

abstract：:Sound production is a widespread phenomenon among animals. Effective sound use for mate or species recognition requires some acoustic differentiation at an individual or species level. Several species of caudate amphibians produce underwater sounds, but information about intra- and interspecific variation in their aco...

journal_title：PeerJ

authors： Hubáček J,Šugerková M,Gvoždík L

更新日期：2019-03-28 00:00:00

abstract：BACKGROUND:Antimicrobial peptides (AMPs) are of great potential as novel antibiotics for the treatment of broad spectrum of pathogenic microorganisms including resistant bacteria. In this study, the mechanisms of action and the therapeutic efficacy of the hybrid peptides were examined. METHODS:TEM, SEM and ATP efflux ...

journal_title：PeerJ

authors： Jindal HM,Zandi K,Ong KC,Velayuthan RD,Rasid SM,Samudi Raju C,Sekaran SD

更新日期：2017-10-05 00:00:00

abstract：:Anemones of genus Exaiptasia are used as model organisms for the study of cnidarian-dinoflagellate (genus Symbiodinium) endosymbiosis. However, while most reef-building corals harbor Symbiodinium of clade C, Exaiptasia spp. anemones mainly harbor clade B Symbiodinium (ITS2 type B1) populations. In this study, we revea...

journal_title：PeerJ

authors： Chen WN,Hsiao YJ,Mayfield AB,Young R,Hsu LL,Peng SE

更新日期：2016-08-24 00:00:00

abstract：:Here we review the systematics of the threadsnakes of the Epictia goudotii Species complex in Middle and northern South America using external morphology and molecular data. Two species, Epictia goudotii and E. magnamaculata, are currently recognized from that region, but we provide evidence for recognizing, as specie...

journal_title：PeerJ

authors： McCranie JR,Hedges SB

更新日期：2016-01-12 00:00:00

abstract：:The nursery function of coastal habitats is one of the most frequently mentioned and recognized ecosystem services in the valuation of coastal ecosystems. Despite its importance our understanding of the precise habitat parameters and mechanisms that make a habitat important as a nursery area is still limited for many ...

journal_title：PeerJ

authors： Hinz H,Reñones O,Gouraguine A,Johnson AF,Moranta J

更新日期：2019-05-15 00:00:00

abstract：:Coastal birds are critical ecosystem constituents on sandy shores, yet are threatened by depressed reproductive success resulting from direct and indirect anthropogenic and natural pressures. Few studies examine clutch fate across the wide range of environments experienced by birds; instead, most focus at the small si...

journal_title：PeerJ

authors： Maslo B,Schlacher TA,Weston MA,Huijbers CM,Anderson C,Gilby BL,Olds AD,Connolly RM,Schoeman DS

更新日期：2016-09-13 00:00:00

abstract：:This paper investigates the capabilities of the evolutionary fuzzy genetic (FG) approach and compares it with three neuro-fuzzy methods-neuro-fuzzy with grid partitioning (ANFIS-GP), neuro-fuzzy with subtractive clustering (ANFIS-SC), and neuro-fuzzy with fuzzy c-means clustering (ANFIS-FCM)-in terms of modeling long-...

journal_title：PeerJ

authors： Sadeghi-Niaraki A,Kisi O,Choi SM

更新日期：2020-08-14 00:00:00

abstract：:In this study, silver nanoparticles (NP) were synthesized by two methods: using an aqueous extract of Mentha spicata leaves and using citrate ions as stabilizing agent, and the cytotoxicity and anticancer activity of both NP were evaluated in vitro. The particles synthesized with the aqueous extract were spherical wit...

journal_title：PeerJ

authors： Torres-Martínez Y,Arredondo-Espinoza E,Puente C,González-Santiago O,Pineda-Aguilar N,Balderas-Rentería I,López I,Ramírez-Cabrera MA

更新日期：2019-12-09 00:00:00

abstract：:NA-glycine is an endogenous lipid molecule with analgesic properties, which is structurally similar to the endocannabinoids 2-AG and anandamide but does not interact with cannabinoid receptors. NA-glycine has been suggested to act at the G-protein coupled receptors GPR18 and GPR92. Recently, we have described that NA-...

journal_title：PeerJ

authors： Baur R,Gertsch J,Sigel E

更新日期：2013-09-10 00:00:00

abstract：BACKGROUND:Cloud forests, characterized by a persistent, frequent or seasonal low-level cloud cover and fragmented distribution, are one of the most threatened habitats, especially in the Neotropics. Tree ferns are among the most conspicuous elements in these forests, and ferns are restricted to regions in which minimu...

journal_title：PeerJ

authors： Sosa V,Ornelas JF,Ramírez-Barahona S,Gándara E

更新日期：2016-11-16 00:00:00

abstract：:Limestone karsts of Southeast Asia can harbor high levels of endemism, but are highly fragmented, increasingly threatened, and their biodiversity is often poorly studied. This is true of the Padawan Limestone Area of Sarawak, Malaysia, home to the endemic Artocarpus annulatus, the closest known wild relative of two im...

journal_title：PeerJ

authors： Dickinson L,Noble H,Gardner E,Puad ASA,Zakaria WNFW,Zerega NJC

更新日期：2020-09-21 00:00:00

abstract：BACKGROUND:Profiling of microbial communities via metagenomic shotgun sequencing has enabled researches to gain unprecedented insight into microbial community structure and the functional roles of community members. This study describes a method and basic analysis for a metagenomic adaptation of the double digest restr...

journal_title：PeerJ

authors： Liu MY,Worden P,Monahan LG,DeMaere MZ,Burke CM,Djordjevic SP,Charles IG,Darling AE

更新日期：2017-09-19 00:00:00

abstract：:We revise the taxonomy of the myrmicine ants of the Monomorium monomorium species-group for the Arabian Peninsula. Six species are recognized: Monomorium aeyade Collingwood & Agosti, 1996, M. clavicorne André, 1881, M. exiguum Forel, 1894, M. holothir Bolton, 1987, M. mohammedi sp. n., and M. sarawatense Sharaf & Alda...

journal_title：PeerJ

authors： Sharaf M,Al Dhafer HM,Aldawood AS,Hita Garcia F

更新日期：2018-02-01 00:00:00

abstract：:Background. India accounts for 24% to all under-five mortality in the world. Residence in rural area, poverty and low levels of mother's education are known confounders of under-five mortality. Since two-thirds of India's population lives in rural areas, mothers employed in agriculture present a particularly vulnerabl...

journal_title：PeerJ

authors： Singh R,Tripathi V

更新日期：2015-01-08 00:00:00

abstract：:A representative outcrop of the Messinian stromatolites belonging to the Terminal Carbonate Complex unit, from the northern sector of the Bajo Segura basin (Caja de Ahorros del Mediterraneo section, Sierra del Colmenar, SE Spain) has been studied. Here, we present a detailed analysis of the architecture, external morp...

journal_title：PeerJ

authors： Villafañe PG,Corbí H,Cónsole-Gonella C,Ruiz-Sánchez FJ,Soria JM

更新日期：2018-10-16 00:00:00

abstract：:Currently there are 21 shrimp species in the northeastern Atlantic and Mediterranean Sea which are considered to belong to the superfamily Oplophoroidea, but the larval development is unknown for most of them. The complete larval development of Systellaspis debilis (Milne-Edwards, 1881), here described and illustrated...

journal_title：PeerJ

authors： Bartilotti C,Dos Santos A

更新日期：2019-09-18 00:00:00

abstract：Background:To ensure the safety of trees, two NDT (nondestructive testing) techniques, electric resistance tomography and stress wave tomography, were employed to quantitatively detect and characterize the internal decay of standing trees. Comparisons between those two techniques were done to make full use of the indiv...

journal_title：PeerJ

authors： Yue X,Wang L,Wacker JP,Zhu Z

更新日期：2019-03-05 00:00:00

abstract：Background:Systemic inflammation and nutritional status both play roles in the survival of cancer patients. Therefore, it is important to understand the effects of prognostic nutritional index (PNI) and lymphocyte-to-monocyte ratio (LMR) on the survival of patients with advanced p16-negative oropharyngeal cancer. Meth...

journal_title：PeerJ

authors： Tsai MH,Huang TL,Chuang HC,Lin YT,Fang FM,Lu H,Chien CY

更新日期：2020-12-01 00:00:00

abstract：:The knowledge on the spatial distribution of soil available water capacity at a regional or national extent is essential, as soil water capacity is a component of the water and energy balances in the terrestrial ecosystem. It controls the evapotranspiration rate, and has a major impact on climate. This paper demonstra...

journal_title：PeerJ

authors： Hong SY,Minasny B,Han KH,Kim Y,Lee K

更新日期：2013-04-23 00:00:00

abstract：:Multimodal imaging enables sensitive measures of the architecture and integrity of the human brain, but the high-dimensional nature of advanced brain imaging features poses inherent challenges for the analyses and interpretations. Multivariate age prediction reduces the dimensionality to one biologically informative s...

journal_title：PeerJ

authors： Richard G,Kolskår K,Sanders AM,Kaufmann T,Petersen A,Doan NT,Monereo Sánchez J,Alnæs D,Ulrichsen KM,Dørum ES,Andreassen OA,Nordvik JE,Westlye LT

更新日期：2018-11-30 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess the effects of age, body condition score (BCS) and muscle condition score (MCS) on indirect radial and coccygeal Doppler systolic arterial blood pressure (SAP) measurements in dogs. METHODS:Sixty-two privately-owned dogs were enrolled between June and July 2016. The BC...

journal_title：PeerJ

authors： Mooney AP,Mawby DI,Price JM,Whittemore JC

更新日期：2017-03-22 00:00:00

abstract：:Rhynchosauria is a group of archosauromorph reptiles abundant in terrestrial ecosystems of the Middle Triassic. Mesosuchus is one of the earliest and basalmost rhynchosaurs, playing an important role not only for the understanding of the evolution of the group as a whole, but also of archosauromorphs in general. The b...

journal_title：PeerJ

authors： Sobral G,Müller J

更新日期：2019-05-22 00:00:00

abstract：:Individual movement influences the spatial and social structuring of a population. Animals regularly use the same paths to move efficiently to familiar places, or to patrol and mark home ranges. We found that Australian sleepy lizards (Tiliqua rugosa), a monogamous species with stable pair-bonds, repeatedly used the s...

journal_title：PeerJ

authors： Leu ST,Jackson G,Roddick JF,Bull CM

更新日期：2016-03-22 00:00:00

abstract：Background:Skeletal muscle wound healing is dependent on complex interactions between fibroblasts, myofibroblasts, myogenic cells, and cytokines, such as TGF-β1. This study sought to clarify the impact of TGF-β1 signaling on skeletal muscle cells and discern between the individual contributions of fibroblasts and myofi...

journal_title：PeerJ

authors： Krieger J,Park BW,Lambert CR,Malcuit C

更新日期：2018-07-11 00:00:00

abstract：:According to current molecular evidence, the Chionaspis pinifoliae heterophyllae species complex has been recognized as 10 cryptic species. In this study, we construct potential distribution maps for seven cryptic species based on climatic variables. This was done to assess the main environmental factors that have con...

journal_title：PeerJ

authors： Zhao Q,Zhang H,Wei J

更新日期：2019-05-31 00:00:00

abstract：:Network motifs play an important role in the structural analysis of biological networks. Identification of such network motifs leads to many important applications such as understanding the modularity and the large-scale structure of biological networks, classification of networks into super-families, and protein func...

journal_title：PeerJ

authors： Patra S,Mohapatra A

更新日期：2019-05-17 00:00:00

abstract：Purpose:To explore whether unilateral relapse of Bechet's disease-associated uveitis (BDU) causes differences in the tear proteome between the diseased and the contralateral quiescent eye and potential tear biomarkers for uveitis recurrence and disease monitoring. Method:To minimize interindividual variations, bilater...

journal_title：PeerJ

authors： Liang A,Qin W,Zhang M,Gao F,Zhao C,Gao Y

更新日期：2020-06-19 00:00:00