Do N-arachidonyl-glycine (NA-glycine) and 2-arachidonoyl glycerol (2-AG) share mode of action and the binding site on the β2 subunit of GABAA receptors?

abstract：:Insect pollinators provide an essential ecosystem service by transferring pollen to crops and native vegetation. The extent to which pollinator communities vary both spatially and temporally has important implications for ecology, conservation and agricultural production. However, understanding the complex interaction...

journal_title：PeerJ

authors： Willcox BK,Robson AJ,Howlett BG,Rader R

更新日期：2018-10-19 00:00:00

abstract：BACKGROUND:Recent climatic history has strongly impacted plant populations, but little is known about its effect on microbes. Alders, which host few and specific symbionts, have high genetic diversity in glacial refugia. Here, we tested the prediction that communities of root symbionts survived in refugia with their ho...

journal_title：PeerJ

authors： Roy M,Pozzi AC,Gareil R,Nagati M,Manzi S,Nouioui I,Sharikadze N,Jargeat P,Gryta H,Moreau PA,Fernandez MP,Gardes M

更新日期：2017-07-18 00:00:00

abstract：Background:Acute respiratory distress syndrome (ARDS) is associated with significantly increased risk of death, and early risk stratification may help to choose the appropriate treatment. The study aimed to develop a neural network model by using a genetic algorithm (GA) for the prediction of mortality in patients with...

journal_title：PeerJ

authors： Zhang Z

更新日期：2019-09-16 00:00:00

abstract：Background/Aims:Medical and behavioral needs are relevant in organizing and providing support strategies that improve the quality of life for children, along with their families. The present study aims to examine the impact of medical and behavioral needs on the need for support of children with disabilities. Methods:...

journal_title：PeerJ

authors： Arias VB,Aguayo V,Verdugo MA,Amor AM

更新日期：2020-09-15 00:00:00

abstract：Background:Over the last two decades, there has been a constant increase in prescription rates of antidepressants. In parallel, neuroactive pharmaceuticals are making their way into aquatic environments at increasing concentrations. Among the antidepressants detected in the environment citalopram, a selective serotonin...

journal_title：PeerJ

authors： Ziegler M,Knoll S,Köhler HR,Tisler S,Huhn C,Zwiener C,Triebskorn R

更新日期：2020-03-12 00:00:00

abstract：:On the purpose of enhancing the forensic efficiency of CODIS STR loci, new STR loci have been gradually discovered and developed into some commercial multiplex systems. Recently, 22 STR loci including 18 non-CODIS STR loci and four CODIS STR loci were investigated in 501 unrelated healthy individuals of Kazakh ethnic ...

journal_title：PeerJ

authors： Chen C,Guo Y,Jin X,Cui W,Wei Y,Fang Y,Lan Q,Kong T,Xie T,Zhu B

更新日期：2019-04-25 00:00:00

abstract：Aims:Periodontitis and psoriatic disease, including psoriasis (PS) and psoriatic arthritis (PsA), share the common risk factors and co-morbidities. However, the risk of periodontitis in patients with psoriatic disease still needs further investigation. This study was a nationwide population-based retrospective cohort s...

journal_title：PeerJ

authors： Su NY,Huang JY,Hu CJ,Yu HC,Chang YC

更新日期：2017-11-16 00:00:00

abstract：:Environmental heterogeneity affects not only the distribution of a species but also its local abundance. High heterogeneity due to habitat alteration and fragmentation can influence the realized niche of a species, lowering habitat suitability as well as reducing local abundance. We investigate whether a relationship ...

journal_title：PeerJ

authors： Basile M,Valerio F,Balestrieri R,Posillico M,Bucci R,Altea T,De Cinti B,Matteucci G

更新日期：2016-09-08 00:00:00

abstract：:Histone deacetylases (HDACs) are key epigenetic factors in regulating chromatin structure and gene expression in multiple aspects of plant growth, development, and response to abiotic or biotic stresses. Many studies on systematic analysis and molecular function of HDACs in Arabidopsis and rice have been conducted. Ho...

journal_title：PeerJ

authors： Zhang K,Yu L,Pang X,Cao H,Si H,Zang J,Xing J,Dong J

更新日期：2020-02-12 00:00:00

abstract：:In this study, four experimental assays were conducted to evaluate the use of a new silver nanoparticle formulation named Argovit-4, which was prepared with slight modifications to enhance its biological activity against white spot syndrome virus (WSSV) in shrimp culture. The goals of these assays were to (1) determin...

journal_title：PeerJ

authors： Romo-Quiñonez CR,Álvarez-Sánchez AR,Álvarez-Ruiz P,Chávez-Sánchez MC,Bogdanchikova N,Pestryakov A,Mejia-Ruiz CH

更新日期：2020-02-27 00:00:00

abstract：BACKGROUND:The rice receptor kinase XA21 confers robust resistance to the bacterial pathogen Xanthomonas oryzaepv. oryzae(Xoo). We previously reported that XA21 is cleaved in transgenic plants overexpressing XA21 with a GFP tag (Ubi-XA21-GFP) and that the released C-terminal domain is localized to the nucleus. XA21 car...

journal_title：PeerJ

authors： Wei T,Chen TC,Ho YT,Ronald PC

更新日期：2016-10-05 00:00:00

abstract：Background:During their long evolution, Synechocystis sp. PCC6803 developed a remarkable capacity to acclimate to diverse environmental conditions. In this study, Raman spectroscopy and Raman chemometrics tools (RametrixTM) were employed to investigate the phenotypic changes in response to external stressors and correl...

journal_title：PeerJ

authors： Tanniche I,Collakova E,Denbow C,Senger RS

更新日期：2020-03-30 00:00:00

abstract：:We provided chimpanzees (Pan troglodytes) with the ability to improve the quality of food rewards they received in a dyadic test of inequity. We were interested to see if this provision influenced their responses and, if so, whether it was mediated by a social partner's outcomes. We tested eight dyads using an exchang...

journal_title：PeerJ

authors： Hopper LM,Lambeth SP,Schapiro SJ,Brosnan SF

更新日期：2013-09-17 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the effects of low-volume high-intensity interval training and continuous low to moderate intensity training on quality of life, functional capacity and cardiovascular disease risk factors in cancer survivors. METHODS:Cancer survivors within 24 months post-diagnosis were r...

journal_title：PeerJ

authors： Toohey K,Pumpa KL,Arnolda L,Cooke J,Yip D,Craft PS,Semple S

更新日期：2016-10-20 00:00:00

abstract：:Amazonian bamboo forests dominated by large woody bamboo plants in the genus Guadua cover approximately 180,000 km2 and represent a key resource for many organisms. In southwestern Amazonia, native bamboo forests differ in structure, biodiversity, and growth dynamics from other forest types in the region. However, wit...

journal_title：PeerJ

authors： Jacobs JM,von May R,Kavanaugh DH,Connor EF

更新日期：2018-07-03 00:00:00

abstract：:Background. Eucryptodiran turtles from the Late Jurassic (mainly Kimmeridgian) deposits of the Jura Mountains (Switzerland and France) are among the earliest named species traditionally referred to the Plesiochelyidae, Thalassemydidae, and Eurysternidae. As such, they are a reference for the study of Late Jurassic euc...

journal_title：PeerJ

authors： Anquetin J,Püntener C,Billon-Bruyat JP

更新日期：2014-05-13 00:00:00

abstract：:The selection and validation of proper distinguishing characters are of crucial importance in taxonomic revisions. The modern classifications of orchids utilize the molecular tools, but still the selection and identification of the material used in these studies is for the most part related to general species morpholo...

journal_title：PeerJ

authors： Jakubska-Busse A,Żołubak E,Łobas Z,Gola EM

更新日期：2017-07-21 00:00:00

abstract：:As conspicuous modular components of benthic marine habitats, gorgonian (sea fan) octocorals have perplexed taxonomists for centuries through their shear diversity, particularly throughout the Indo-Pacific. Phenotypic incongruence within and between seemingly unitary lineages across contrasting environments can provid...

journal_title：PeerJ

authors： Rowley SJ,Pochon X,Watling L

更新日期：2015-08-20 00:00:00

abstract：:Histopathological images contain rich phenotypic descriptions of the molecular processes underlying disease progression. Convolutional neural networks, state-of-the-art image analysis techniques in computer vision, automatically learn representative features from such images which can be useful for disease diagnosis, ...

journal_title：PeerJ

authors： Lu L,Daigle BJ Jr

更新日期：2020-03-12 00:00:00

abstract：:Purple Broccoli (Brassica oleracea L. var italica) attracts growing attention as a functional food. Its purple coloration is due to high anthocyanin amounts. Light represents a critical parameter affecting anthocyanins biosynthesis. In this study, 'Purple Broccoli', a light-responding pigmentation cultivar, was assess...

journal_title：PeerJ

authors： Liu C,Yao X,Li G,Huang L,Xie Z

更新日期：2020-05-05 00:00:00

abstract：:Forest soils sequester a large amount of carbon (C) and have a significant effect on the global C balance. Forests are commonly managed to maintain certain age structures but the effects of this management on soil C pools (kg C m-2) is still uncertain. We compared 40-year-old (1GF) and 24-year-old (2GF) plantations of...

journal_title：PeerJ

authors： Ma J,Han H,Cheng X

更新日期：2020-01-21 00:00:00

abstract：:Microbial transglutaminase (mTG) was used as a crosslinking agent in the preparation of gelatin sponges. The physical properties of the materials were evaluated by measuring their material porosity, water absorption, and elastic modulus. The stability of the sponges were assessed via hydrolysis and enzymolysis. To stu...

journal_title：PeerJ

authors： Long H,Ma K,Xiao Z,Ren X,Yang G

更新日期：2017-08-09 00:00:00

abstract：Background:Quantifying lower-limb load and asymmetry during team sport match-play may be important for injury prevention and understanding performance. However, current analysis methods of lower-limb symmetry during match-play employ wearable microtechnology that may not be best suited to the task. A popular microtechn...

journal_title：PeerJ

authors： Glassbrook DJ,Fuller JT,Alderson JA,Doyle TLA

更新日期：2020-06-23 00:00:00

abstract：Background:Prognostic genes in the tumor microenvironment play an important role in immune biological processes and the response of cancer to immunotherapy. Thus, we aimed to assess new biomarkers that are associated with immune/stromal cells in lung adenocarcinomas (LUAD) using the ESTIMATE algorithm, which also signi...

journal_title：PeerJ

authors： Xu ZY,Zhao M,Chen W,Li K,Qin F,Xiang WW,Sun Y,Wei J,Yuan LQ,Li SK,Lin SH

更新日期：2020-07-23 00:00:00

abstract：:Weevils (Coleoptera: Curculionoidea) represent one of the most diverse groups of organisms on Earth; interactions with their host plants have been recognized to play a central role in their remarkable diversity, yet the exact mechanisms and factors still remain poorly understood. Using phylogenetic comparative analyse...

journal_title：PeerJ

authors： Hernández-Vera G,Toševski I,Caldara R,Emerson BC

更新日期：2019-03-20 00:00:00

abstract：:Koalas (Phascolarctos cinereus) are highly specialized herbivorous marsupials that feed almost exclusively on Eucalyptus leaves, which are known to contain varying concentrations of many different toxic chemical compounds. The literature suggests that Lonepinella koalarum, a bacterium in the Pasteurellaceae family, ca...

journal_title：PeerJ

authors： Dahlhausen KE,Jospin G,Coil DA,Eisen JA,Wilkins LGE

更新日期：2020-10-20 00:00:00

abstract：Background:Cholera, an acute enteric infection, is a serious health challenge in both the underdeveloped and the developing world. It is caused by Vibrio cholerae after ingestion of fecal contaminated food or water. Cholera outbreaks have recently been observed in regions facing natural calamities (i.e., earthquake in ...

journal_title：PeerJ

authors： Rashid MI,Rehman S,Ali A,Andleeb S

更新日期：2019-06-19 00:00:00

abstract：BACKGROUND:Estimating volumes and masses of total body components is important for the study and treatment monitoring of nutrition and nutrition-related disorders, cancer, joint replacement, energy-expenditure and exercise physiology. While several equations have been offered for estimating total body components from M...

journal_title：PeerJ

authors： Lacoste Jeanson A,Dupej J,Villa C,Brůžek J

更新日期：2017-05-18 00:00:00

abstract：AIM:To prospectively evaluate the effects of vitamin D3 on disease activity and quality of life in ulcerative colitis (UC) patients with hypovitaminosis D. METHODS:The study was a prospective double-blinded, randomized trial conducted at Community Regional Medical Center, Fresno, CA from 2012-2013. Patients with UC an...

journal_title：PeerJ

authors： Mathur J,Naing S,Mills P,Limsui D

更新日期：2017-08-03 00:00:00

abstract：Background:Cognitive dysfunction in fibromyalgia (FM) encompasses objective cognitive difficulties, as measured in neuropsychological tests, and self-reported cognitive complaints. Although it has been suggested that FM patients display problems in working memory, the data are inconsistent, and the overall working memo...

journal_title：PeerJ

authors： Pidal-Miranda M,González-Villar AJ,Carrillo-de-la-Peña MT,Andrade E,Rodríguez-Salgado D

更新日期：2018-11-21 00:00:00