Analysis of prognostic genes in the tumor microenvironment of lung adenocarcinoma.

abstract：:Background. The impact of head and neck cancer (HNC) in long-term survivors differs widely among individuals, and a significant number of them suffer from the negative effects of disease, whereas others report significant positive effect. This systematic review investigated the evidence the implications of treatment f...

journal_title：PeerJ

authors： Harding S,Sanipour F,Moss T

更新日期：2014-02-11 00:00:00

abstract：Background:Geographic variation in body size and condition can reveal differential local adaptation to resource availability or climatic factors. Body size and condition are related to fitness in garter snakes (Thamnophis), thus good body condition may increase survival, fecundity in females, and mating success in male...

journal_title：PeerJ

authors： Valencia-Flores E,Venegas-Barrera CS,Fajardo V,Manjarrez J

更新日期：2019-03-13 00:00:00

abstract：:Live trapping is a common tool used to assess demography of small mammals. However, live-trapping is often expensive and stressful to captured individuals. Thus, assessing the relative tradeoffs among study goals, project expenses, and animal well-being is necessary. Here, we evaluated how apparent bias and precision ...

journal_title：PeerJ

authors： Weldy MJ,Wilson TM,Lesmeister DB,Epps CW

更新日期：2019-10-03 00:00:00

abstract：:The etiology of cancer includes aberrant cellular homeostasis where a compromised RNA regulatory network is a prominent contributing factor. In particular, noncoding RNAs including microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) were recently shown to play important roles in the initiation, progression, and metas...

journal_title：PeerJ

authors： Ning P,Wu Z,Hu A,Li X,He J,Gong X,Xia Y,Shang Y,Bian H

更新日期：2018-01-12 00:00:00

abstract：:Background. A "cafeteria" diet is a self-selected high-fat diet, providing an excess of energy, which can induce obesity. Excess of lipids in the diet hampers glucose utilization eliciting insulin resistance, which, further limits amino acid oxidation for energy. Methods. Male Wistar rats were exposed for a month to "...

journal_title：PeerJ

authors： Sabater D,Agnelli S,Arriarán S,Romero Mdel M,Fernández-López JA,Alemany M,Remesar X

更新日期：2016-08-03 00:00:00

abstract：Background:The coral genus Acropora contains more than 150 species with very high morphological diversity. This high diversity may have been caused by repeated hybridization via mass spawning. However, we have little information whether hybrids are formed in these corals. Identifying morphological differences between h...

journal_title：PeerJ

authors： Fukami H,Iwao K,Kumagai NH,Morita M,Isomura N

更新日期：2019-02-19 00:00:00

abstract：:The mature spermatozoa of Stephanostomum murielae and Stephanostomoides tenuis are described by transmission electron microscopy. They present several ultrastructural features previously reported in other digeneans. Their spermatozoa possess two axonemes of different length showing the 9 + '1' trepaxonematan pattern, ...

journal_title：PeerJ

authors： Bakhoum AJ,Quilichini Y,Justine JL,Bray RA,Bâ CT,Marchand B

更新日期：2015-02-12 00:00:00

abstract：:We provided chimpanzees (Pan troglodytes) with the ability to improve the quality of food rewards they received in a dyadic test of inequity. We were interested to see if this provision influenced their responses and, if so, whether it was mediated by a social partner's outcomes. We tested eight dyads using an exchang...

journal_title：PeerJ

authors： Hopper LM,Lambeth SP,Schapiro SJ,Brosnan SF

更新日期：2013-09-17 00:00:00

abstract：:The Cuatro Ciénegas Basin (CCB) comprises several oligotrophic aquatic ecosystems limited by phosphorus. These aquatic systems are dominated by a high prokaryotic diversity, shaped by the stress of low nutrient supplies and interspecific competition. Although fungi constitute a diverse and important component of micro...

journal_title：PeerJ

authors： Velez P,Gasca-Pineda J,Rosique-Gil E,Eguiarte LE,Espinosa-Asuar L,Souza V

更新日期：2016-06-02 00:00:00

abstract：BACKGROUND:The purpose of this study is to provide a report on scientific production during the period 2010-2014 in order to identify the major topics as well as the predominant actors (journals, countries, continents) involved in the field of eye disease. METHODS:A PubMed search was carried out to extract articles re...

journal_title：PeerJ

authors： Boudry C,Denion E,Mortemousque B,Mouriaux F

更新日期：2016-01-07 00:00:00

abstract：:A range of diseases is associated with amyloid fibril formation. Despite different proteins being responsible for each disease, all of them share similar features including beta-sheet-rich secondary structure and fibril-like protein aggregates. A number of proteins can form amyloid-like fibrils in vitro, resembling st...

journal_title：PeerJ

authors： Šneideris T,Baranauskienė L,Cannon JG,Rutkienė R,Meškys R,Smirnovas V

更新日期：2015-09-24 00:00:00

abstract：:In summer 2012, we initiated a large-scale field experiment in southern Ontario, Canada, to determine whether exposure to clothianidin seed-treated canola (oil seed rape) has any adverse impacts on honey bees. Colonies were placed in clothianidin seed-treated or control canola fields during bloom, and thereafter were ...

journal_title：PeerJ

authors： Cutler GC,Scott-Dupree CD,Sultan M,McFarlane AD,Brewer L

更新日期：2014-10-30 00:00:00

abstract：:Bacterial vaginosis (BV) is one of most common vaginal infections. However, its diagnosis by classical methods reveals low specificity. Our goal was to evaluate the accuracy diagnosis of 150 vaginal samples with research gold standard methods and our Peptide Nucleic Acid (PNA) probes by Fluorescence in situ Hybridizat...

journal_title：PeerJ

authors： Machado A,Castro J,Cereija T,Almeida C,Cerca N

更新日期：2015-02-17 00:00:00

abstract：:The species of poorly known but charismatic genera Haematodes Laporte, 1835 and Weiserianum Bernhauer, 1927 are revised. Weiserianumsyn. nov. is considered a junior synonym of Haematodes, with Haematodes kuntzeni (Scheerpeltz, 1936) comb. nov.Weiserianum woltersi Bernhauer, 1927 syn. nov. is treated as a synonym of Ha...

journal_title：PeerJ

authors： Brunke AJ,Chatzimanolis S

更新日期：2018-03-29 00:00:00

abstract：Background:Vegetation in the Mongolian Plateau is very sensitive to climate change, which has a significant impact on the regulation of terrestrial carbon cycle. Methods:We analyzed spatio-temporal changes of both growing season and the seasonal Normalized Difference Vegetation Index (NDVI) using simple linear trend a...

journal_title：PeerJ

authors： Meng M,Huang N,Wu M,Pei J,Wang J,Niu Z

更新日期：2019-09-30 00:00:00

abstract：Objectives:The purpose of this study is to investigate the patterns of complementary and alternative medicine use and its association with time to conventional treatment. Design:A cross-sectional study design was designed. Setting and participants:The study was performed at the Chonburi Cancer Hospital, with chart re...

journal_title：PeerJ

authors： Chotipanich A,Sooksrisawat C,Jittiworapan B

更新日期：2019-06-14 00:00:00

abstract：:As coral reefs continue to decline globally, coral restoration practitioners have explored various approaches to return coral cover and diversity to decimated reefs. While branching coral species have long been the focus of restoration efforts, the recent development of the microfragmentation coral propagation techniq...

journal_title：PeerJ

authors： Koval G,Rivas N,D'Alessandro M,Hesley D,Santos R,Lirman D

更新日期：2020-10-02 00:00:00

abstract：:Many migratory bird species show high levels of site fidelity to their wintering sites, which confers advantages due to prior knowledge, but may also limit the ability of the individual to move away from degrading sites or to detect alternative foraging opportunities. Winter site fidelity often varies among age groups...

journal_title：PeerJ

authors： Lourenço PM,Alves JA,Reneerkens J,Loonstra AJ,Potts PM,Granadeiro JP,Catry T

更新日期：2016-09-28 00:00:00

abstract：:Network motifs play an important role in the structural analysis of biological networks. Identification of such network motifs leads to many important applications such as understanding the modularity and the large-scale structure of biological networks, classification of networks into super-families, and protein func...

journal_title：PeerJ

authors： Patra S,Mohapatra A

更新日期：2019-05-17 00:00:00

abstract：:The mutant form GGBP/H152C of the D-glucose/D-galactose-binding protein with the solvatochromic dye BADAN linked to cysteine residue Cys 152 can be used as a potential base for a sensitive element of glucose biosensor system. We investigated the influence of various external factors on the physical-chemical properties...

journal_title：PeerJ

authors： Fonin AV,Stepanenko OV,Povarova OI,Volova CA,Philippova EM,Bublikov GS,Kuznetsova IM,Demchenko AP,Turoverov KK

更新日期：2014-03-18 00:00:00

abstract：:The capacity for aerial maneuvering was likely a major influence on the evolution of flying animals. Here we evaluate consequences of paravian morphology for aerial performance by quantifying static stability and control effectiveness of physical models for numerous taxa sampled from within the lineage leading to bird...

journal_title：PeerJ

authors： Evangelista D,Cam S,Huynh T,Kwong A,Mehrabani H,Tse K,Dudley R

更新日期：2014-10-16 00:00:00

abstract：Background:Development of incisional complications following ventral median celiotomy might depend on suture pattern for skin closure. Methods:In this prospective study, 21 healthy male horses underwent celiotomy. Skin closure was either performed via a continuous percutaneous pattern (CO group; 5 warmbloods/5 ponies)...

journal_title：PeerJ

authors： Scharner D,Gittel C,Winter K,Blaue D,Schedlbauer C,Vervuert I,Brehm W

更新日期：2018-11-09 00:00:00

abstract：:MicoRNAs (miRNAs), usually as gene regulators, participate in various biological processes, including stress responses. The hypothalamus-pituitary-adrenal axis (HPA axis) is an important pathway in regulating stress response. Although the mechanism that HPA axis regulates stress response has been basically revealed, t...

journal_title：PeerJ

authors： Luo W,Fang M,Xu H,Xing H,Fu J,Nie Q

更新日期：2016-02-18 00:00:00

abstract：:Pseudomonas syringae is the most widespread bacterial pathogen in plants. Several strains of P. syringae produce a phytotoxin, coronatine (COR), which acts as a jasmonic acid mimic and inhibits plant defense responses and contributes to disease symptom development. In this study, we found that COR inhibits early defen...

journal_title：PeerJ

authors： Lee S,Ishiga Y,Clermont K,Mysore KS

更新日期：2013-02-12 00:00:00

abstract：:The active place avoidance task is a dry-arena task used to assess spatial navigation and memory in rodents. In this task, a subject is put on a rotating circular arena and avoids an invisible sector that is stable in relation to the room. Rotation of the arena means that the subject's avoidance must be active, otherw...

journal_title：PeerJ

authors： Bahník Š,Stuchlík A

更新日期：2015-09-22 00:00:00

abstract：Background:The exoskeleton of an insect could be an important factor in the success of its evolutionary process. This reaches its maximum expression in beetles, which constitute the most diversified animal taxon. The involvement in the management of environmental radiation could be one of the most important functions o...

journal_title：PeerJ

authors： Cuesta E,Lobo JM

更新日期：2019-11-25 00:00:00

abstract：:This study evaluated pollution levels in water and sediments of Península de Paraguaná and related these levels with benthic macrofauna along a coastal area where the largest Venezuelan oil refineries have operated over the past 60 years. For this, the concentration of heavy metals, of hydrocarbon compounds and the co...

journal_title：PeerJ

authors： Croquer A,Bone D,Bastidas C,Ramos R,García E

更新日期：2016-06-23 00:00:00

abstract：:The fates of genetic polymorphisms maintained by balancing selection depend on evolutionary dynamics at linked sites. While coevolution across linked, epigenetically-interacting loci has been extensively explored, such supergenes may be relatively rare. However, genes harboring adaptive variation can occur in close ph...

journal_title：PeerJ

authors： Tennessen JA

更新日期：2018-06-28 00:00:00

abstract：:Loss of biodiversity caused by impact of elephants (Loxodonta africana) on African woodlands may require a management response, but any action should be based on an understanding of why elephants choose to utilise trees destructively. Comprehension of elephant feeding behaviour requires consideration of the relative v...

journal_title：PeerJ

authors： Clegg BW,O'Connor TG

更新日期：2017-06-20 00:00:00

abstract：:Previous studies of population genetic structure in Dissostichus eleginoides have shown that oceanographic and geographic discontinuities drive in this species population differentiation. Studies have focused on the genetics of D. eleginoides in the Southern Ocean; however, there is little knowledge of their genetic v...

journal_title：PeerJ

authors： Canales-Aguirre CB,Ferrada-Fuentes S,Galleguillos R,Oyarzun FX,Hernández CE

更新日期：2018-01-16 00:00:00