Determinants of seasonal changes in availability of food patches for elephants (Loxodonta africana) in a semi-arid African savanna.

abstract：:Esophageal cancer is a common malignant tumor in the world, and the aim of this study was to screen key genes related to the development of esophageal cancer using a variety of bioinformatics analysis tools and analyze their biological functions. The data of esophageal squamous cell carcinoma from the Gene Expression ...

journal_title：PeerJ

authors： Guan X,Yao Y,Bao G,Wang Y,Zhang A,Zhong X

更新日期：2020-03-31 00:00:00

abstract：:Weaning is an important event for all mammals, including young forest musk deer. However, weaning stress may cause intestinal microbiota-related disorders. Therefore, high-throughput 16S rRNA gene sequencing was applied to study the dynamic changes in intestinal microbiota during pre-weaning (10 days before weaning) a...

journal_title：PeerJ

authors： Li Y,Shi M,Zhang T,Hu X,Zhang B,Xu S,Ding J,Hu D,Liu S

更新日期：2020-04-13 00:00:00

abstract：Background:Saber-toothed mammals, now all extinct, were cats or "cat-like" forms with enlarged, blade-like upper canines, proposed as specialists in taking large prey. During the last 66 Ma, the saber-tooth ecomorph has evolved convergently at least in five different mammalian lineages across both marsupials and placen...

journal_title：PeerJ

authors： M Janis C,Figueirido B,DeSantis L,Lautenschlager S

更新日期：2020-06-26 00:00:00

abstract：:Environmental DNA (eDNA) is an emerging tool for monitoring invasive and imperiled species, particularly at low densities. However, the factors that control eDNA production, transport, and persistence in aquatic systems remain poorly understood. For example, the extent to which carcasses produce detectable eDNA is unk...

journal_title：PeerJ

authors： Curtis AN,Larson ER

更新日期：2020-06-11 00:00:00

abstract：:The antimicrobial additive triclosan has been used in personal care products widely across the globe for decades. Triclosan resistance has been noted among Vibrio spp., but reports have been anecdotal and the extent of phenotypic triclosan resistance across the Vibrionaceae family has not been established. Here, tricl...

journal_title：PeerJ

authors： Lydon KA,Robertson MJ,Lipp EK

更新日期：2018-07-12 00:00:00

abstract：Background:Laminitis is a common equine disease characterized by foot pain, and is commonly diagnosed using a five-grade Obel system developed in 1948 using sepsis-related cases. However, endocrinopathic laminitis is now the most common form of the disease and clinical signs may be mild, or spread across two Obel grade...

journal_title：PeerJ

authors： Meier A,de Laat M,Pollitt C,Walsh D,McGree J,Reiche DB,von Salis-Soglio M,Wells-Smith L,Mengeler U,Mesa Salas D,Droegemueller S,Sillence MN

更新日期：2019-06-07 00:00:00

abstract：:Studies on the adverse health effects caused by azo dyes are insufficient and quite contradictory. This work aims to investigate the possible toxic effect of two types of widely used food additives, Sunset Yellow and Allura Red, by assessing the physiological, histopathological and ultrastructural changes in the liver...

journal_title：PeerJ

authors： Khayyat LI,Essawy AE,Sorour JM,Soffar A

更新日期：2018-09-28 00:00:00

abstract：:Insect pollinators provide an essential ecosystem service by transferring pollen to crops and native vegetation. The extent to which pollinator communities vary both spatially and temporally has important implications for ecology, conservation and agricultural production. However, understanding the complex interaction...

journal_title：PeerJ

authors： Willcox BK,Robson AJ,Howlett BG,Rader R

更新日期：2018-10-19 00:00:00

abstract：:In Western countries dogs and cats are the most popular pets, and people are increasingly opposed to their rearing for the fur industry. In 2007, a Regulation of the European Union (EU) banned the use and trade of dog and cat furs, but an official analytical protocol to identify them as source species was not provided...

journal_title：PeerJ

authors： Garofalo L,Mariacher A,Fanelli R,Fico R,Lorenzini R

更新日期：2018-06-05 00:00:00

abstract：:Sugarcane-soybean intercropping has been widely used to control disease and improve nutrition in the field. However, the response of the soil microbial community diversity and structure to intercropping is not well understood. Since microbial diversity corresponds to soil quality and plant health, a pot experiment was...

journal_title：PeerJ

authors： Lian T,Mu Y,Jin J,Ma Q,Cheng Y,Cai Z,Nian H

更新日期：2019-02-08 00:00:00

abstract：Background:Little is known regarding the toxic and therapeutic doses of amygdalin. Treatment regimens and schedules can vary between humans and animal models, and there have been reports of cyanide toxicity due to amygdalin use. Objective:The aim of this study was to evaluate the effect of different doses of amygdalin...

journal_title：PeerJ

authors： Albogami S,Hassan A,Ahmed N,Alnefaie A,Alattas A,Alquthami L,Alharbi A

更新日期：2020-05-21 00:00:00

abstract：Background:Vitamin D 1α-hydroxylase CYP27B1 is the key factor in the vitamin D pathway. Previously, we analyzed the expression of CYP27B1 in human gingival fibroblasts in vitro. In the present study, we analyzed the gingival expression of CYP27B1 in vivo. Methods:Forty-two patients with periodontitis Stage IV Grade C ...

journal_title：PeerJ

authors： Liu K,Han B,Hou J,Zhang J,Su J,Meng H

更新日期：2021-01-04 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most heterogeneous malignant cancers with no effective targets and treatments. However, the molecular pathogenesis of HCC remains largely uncertain. The aims of our study were to find crucial genes involved in HCC through multidimensional methods and revealed potential mole...

journal_title：PeerJ

authors： Liu ZK,Zhang RY,Yong YL,Zhang ZY,Li C,Chen ZN,Bian H

更新日期：2019-08-08 00:00:00

abstract：Background:The highest rate of cancer-related deaths worldwide is from lung adenocarcinoma (LUAD) annually. Metabolism was associated with tumorigenesis and cancer development. Metabolic-related genes may be important biomarkers and metabolic therapeutic targets for LUAD. Materials and Methods:In this study, the glean...

journal_title：PeerJ

authors： Zhao Z,He B,Cai Q,Zhang P,Peng X,Zhang Y,Xie H,Wang X

更新日期：2020-09-24 00:00:00

abstract：:Analysis of calcium sparks in cardiomyocytes can provide valuable information about functional changes of calcium handling in health and disease. As a part of the calcium sparks analysis, sparks detection and characterization is necessary. Here, we describe a new open-source platform for automatic calcium sparks detec...

journal_title：PeerJ

authors： Laasmaa M,Karro N,Birkedal R,Vendelin M

更新日期：2019-03-29 00:00:00

abstract：:The ubiquitin-proteasome system targets misfolded proteins for degradation. Since the accumulation of such proteins is potentially harmful for the cell, their prompt removal is important. E3 ubiquitin-protein ligases mediate substrate ubiquitination by bringing together the substrate with an E2 ubiquitin-conjugating e...

journal_title：PeerJ

authors： Boomsma W,Nielsen SV,Lindorff-Larsen K,Hartmann-Petersen R,Ellgaard L

更新日期：2016-02-25 00:00:00

abstract：:NA-glycine is an endogenous lipid molecule with analgesic properties, which is structurally similar to the endocannabinoids 2-AG and anandamide but does not interact with cannabinoid receptors. NA-glycine has been suggested to act at the G-protein coupled receptors GPR18 and GPR92. Recently, we have described that NA-...

journal_title：PeerJ

authors： Baur R,Gertsch J,Sigel E

更新日期：2013-09-10 00:00:00

abstract：:Synechococcus is among the most important contributors to global primary productivity. The genomes of several strains of this taxon have been previously sequenced in an effort to understand the physiology and ecology of these highly diverse microorganisms. Here we present a comparative study of Synechococcus genomes. ...

journal_title：PeerJ

authors： Coutinho F,Tschoeke DA,Thompson F,Thompson C

更新日期：2016-01-14 00:00:00

abstract：Background:The coronavirus 19 (COVID-19) pandemic has heightened the threat to the health and lives of patients with comorbid diseases. Infection by COVID-19 is especially detrimental to patients on hemodialysis. In this study, we evaluated the clinical characteristics, laboratory findings, treatments and prognoses of ...

journal_title：PeerJ

authors： Luo Y,Li J,Liu Z,Yu H,Peng X,Cao C

更新日期：2020-11-26 00:00:00

abstract：:While there have been increasing numbers of reports of human-wolf conflict in China during recent years, little is known about the nature of this conflict. In this study, we used questionnaires and semi-structured interviews to investigate local villagers' perceptions of wolves in Jiuzhaigou County, western China. We ...

journal_title：PeerJ

authors： Xu Y,Yang B,Dou L

更新日期：2015-06-09 00:00:00

abstract：:Motor unit synchronization is the tendency of motor neurons and their associated muscle fibers to discharge near-simultaneously. It has been theorized as a control mechanism for force generation by common excitatory inputs to these motor neurons. Magnitude of synchronization is calculated from peaks in cross-correlati...

journal_title：PeerJ

authors： Tweedell AJ,Tenan MS

更新日期：2019-12-10 00:00:00

abstract：:We present the first comprehensive review of the present and past shark and ray diversity in marine waters of Tropical America, examining the patterns of distribution in the Eastern Central Pacific (EP) and Western Central Atlantic (WA) realms. We identified the major regions of diversity and of endemism, and explored...

journal_title：PeerJ

authors： Carrillo-Briceño JD,Carrillo JD,Aguilera OA,Sanchez-Villagra MR

更新日期：2018-07-20 00:00:00

abstract：Background:Patellofemoral pain (PFP) is often reported as a diffuse pain at the front of the knee during knee-loading activities. A patient's description of pain location and distribution is commonly drawn on paper by clinicians, which is difficult to quantify, report and compare within and between patients. One way of...

journal_title：PeerJ

authors： Matthews M,Rathleff MS,Vicenzino B,Boudreau SA

更新日期：2018-03-08 00:00:00

abstract：:Unworn teeth of herbivorous mammals are not immediately functional. They have to be partially worn to expose enamel ridges which can then act as shear-cutting blades to break the food down. We use the Plains Zebra (Equus quagga) as a hypsodont, herbivorous model organism to investigate how initial wear of the tooth cr...

journal_title：PeerJ

authors： Winkler DE,Kaiser TM

更新日期：2015-06-11 00:00:00

abstract：:Five tropical seaweeds, Kappaphycus alvarezii (Doty) Doty ex P.C. Silva, Padina australis Hauck, Sargassum binderi Sonder ex J. Agardh (syn. S. aquifolium (Turner) C. Agardh), Sargassum siliquosum J. Agardh and Turbinaria conoides (J. Agardh) Kützing, were incubated in seawater of pH 8.0, 7.8 (ambient), 7.6, 7.4 and 7...

journal_title：PeerJ

authors： Mithoo-Singh PK,Keng FS,Phang SM,Leedham Elvidge EC,Sturges WT,Malin G,Abd Rahman N

更新日期：2017-01-25 00:00:00

abstract：:In species that live in one-male groups, resident males monopolize access to a group of females and are assumed to have higher reproductive success than bachelors. We tested this assumption using genetic, demographic, and behavioral data from 8 groups of wild blue monkeys observed over 10 years to quantify reproductio...

journal_title：PeerJ

authors： Roberts SJ,Cords M

更新日期：2015-06-23 00:00:00

abstract：:We often expect that investigations of the patterns, causes, and consequences of among-individual variation in a trait of interest will reveal how selective pressures or ecological conditions influence that trait. However, many endocrine traits, such as concentrations of glucocorticoid (GC) hormones, exhibit adaptive ...

journal_title：PeerJ

authors： Schoenemann KL,Bonier F

更新日期：2018-02-21 00:00:00

abstract：:Pseudogymnoascus destructans (Pd), the causative agent of white-nose syndrome in bats (WNS), has led to dramatic declines of bat populations in eastern North America. In the spring of 2016, WNS was first detected at several locations in Washington State, USA, which has prompted the need for large scale surveillance ef...

journal_title：PeerJ

authors： Urbina J,Chestnut T,Schwalm D,Allen J,Levi T

更新日期：2020-01-20 00:00:00

abstract：:This study examined whether being aware of the repetition of stimuli in a simple numerosity task could aid the development of automaticity. The numerosity task used in this study was a simple counting task. Thirty-four participants were divided into two groups. One group was instructed that the stimuli would repeat ma...

journal_title：PeerJ

authors： Speelman CP,Shadbolt E

更新日期：2018-01-31 00:00:00

abstract：:Recent years have seen a growing awareness of the role the immune system plays in successful cancer treatment, especially in novel therapies like immunotherapy. The characterization of the immunological composition of tumors and their micro-environment is thus becoming a necessity. In this paper we introduce a deep le...

journal_title：PeerJ

authors： Aprupe L,Litjens G,Brinker TJ,van der Laak J,Grabe N

更新日期：2019-04-10 00:00:00