Abstract:
:Background. A "cafeteria" diet is a self-selected high-fat diet, providing an excess of energy, which can induce obesity. Excess of lipids in the diet hampers glucose utilization eliciting insulin resistance, which, further limits amino acid oxidation for energy. Methods. Male Wistar rats were exposed for a month to "cafeteria" diet. Rats were cannulated and fluorescent microspheres were used to determine blood flow. Results. Exposure to the cafeteria diet did not change cardiac output, but there was a marked shift in organ irrigation. Skin blood flow decreased to compensate increases in lungs and heart. Blood flow through adipose tissue tended to increase in relation to controls, but was considerably increased in brown adipose tissue (on a weight basis). Discussion. The results suggest that the cafeteria diet-induced changes were related to heat transfer and disposal.
journal_name
PeerJjournal_title
PeerJauthors
Sabater D,Agnelli S,Arriarán S,Romero Mdel M,Fernández-López JA,Alemany M,Remesar Xdoi
10.7717/peerj.2302subject
Has Abstractpub_date
2016-08-03 00:00:00pages
e2302issn
2167-8359pii
2302journal_volume
4pub_type
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