Fishing for vaccines against Vibrio cholerae using in silico pan-proteomic reverse vaccinology approach.

abstract：:Teeth have been a focus of research in both extinct and extant taxa alike; a significant portion of dental literature is concerned with dental patterning and replacement. Most non-mammalian vertebrates continuously replace their dentition but an anomalous group of squamates has forgone this process in only having one ...

journal_title：PeerJ

authors： Haridy Y

更新日期：2018-11-08 00:00:00

abstract：:Staphylococcus aureus is a drug-resistant pathogen, capable of colonizing diverse ecological niches and causing a broad spectrum of infections related to a community and healthcare. In this study, we choose four methicillin-resistant S. aureus (MRSA) clinical isolates from Germany and Hungary based on our previous pol...

journal_title：PeerJ

authors： Naorem RS,Blom J,Fekete C

更新日期：2021-01-13 00:00:00

abstract：:In biological research the analysis of gene expression levels in cells and tissues can be a powerful tool to gain insights into biological processes. For this, quantitative RT-PCR (RT-qPCR) is a popular method that often involve the use of constitutively expressed endogenous reference (or 'housekeeping') gene for norm...

journal_title：PeerJ

authors： Svingen T,Letting H,Hadrup N,Hass U,Vinggaard AM

更新日期：2015-03-24 00:00:00

abstract：:Background. Nasal continuous positive airway pressure (nCPAP) is a widely accepted technique of non-invasive respiratory support in premature infants with respiratory distress syndrome due to lack of lung surfactant. If this approach fails, the next step is often intubation, mechanical ventilation (MV) and intratrache...

journal_title：PeerJ

authors： Walther FJ,Hernández-Juviel JM,Waring AJ

更新日期：2014-05-27 00:00:00

abstract：:In recent years, a massive mortality event has killed millions of sea stars, of many different species, along the Pacific coast of North America. This disease event, known as 'sea star wasting disease' (SSWD), is linked to viral infection. In one affected sea star (Pisaster ochraceus), previous work had identified tha...

journal_title：PeerJ

authors： Wares JP,Schiebelhut LM

更新日期：2016-03-29 00:00:00

abstract：:Demand for lumpfish (Cyclopterus lumpus) has increased exponentially over the last decade, both for their roe, which is used as a caviar substitute, and increasingly also as cleaner fish to control sea lice in salmon farming. The species is classified as Near Threatened by the IUCN and there are growing concerns that ...

journal_title：PeerJ

authors： Whittaker BA,Consuegra S,Garcia de Leaniz C

更新日期：2018-11-20 00:00:00

abstract：:Almost all extant testudinids are highly associated with terrestrial habitats and the few tortoises with high affinity to aquatic environments are found within the genus Manouria. Manouria belongs to a clade which forms a sister taxon to all remaining tortoises and is suitable as a model for studying evolutionary tran...

journal_title：PeerJ

authors： Natchev N,Tzankov N,Werneburg I,Heiss E

更新日期：2015-08-11 00:00:00

abstract：:Maternal thyroid hormones (THs) are known to be crucial in embryonic development in humans, but their influence on other, especially wild, animals remains poorly understood. So far, the studies that experimentally investigated the consequences of maternal THs focused on short-term effects, while early organisational e...

journal_title：PeerJ

authors： Sarraude T,Hsu BY,Groothuis T,Ruuskanen S

更新日期：2020-10-16 00:00:00

abstract：:The coccolithophore Emiliania huxleyi forms some of the largest phytoplankton blooms in the ocean. The rapid demise of these blooms has been linked to viral infections. E. huxleyi abundance, distribution, and nutritional status make them an important food source for the heterotrophic protists which are classified as m...

journal_title：PeerJ

authors： Goode AG,Fields DM,Archer SD,Martínez Martínez J

更新日期：2019-04-19 00:00:00

abstract：Background:In arid environments, plant primary productivity is generally low and highly variable both spatially and temporally. Resources are not evenly distributed in space and time (e.g., soil nutrients, water), and depend on global (El Niño/ Southern Oscillation) and local climate parameters. The launch of the Senti...

journal_title：PeerJ

authors： Funghi C,Heim RHJ,Schuett W,Griffith SC,Oldeland J

更新日期：2020-05-26 00:00:00

abstract：:While there have been increasing numbers of reports of human-wolf conflict in China during recent years, little is known about the nature of this conflict. In this study, we used questionnaires and semi-structured interviews to investigate local villagers' perceptions of wolves in Jiuzhaigou County, western China. We ...

journal_title：PeerJ

authors： Xu Y,Yang B,Dou L

更新日期：2015-06-09 00:00:00

abstract：:Palythoa caribaeorum is a zoanthid often dominant in shallow rocky environments along the west coast of the Atlantic Ocean, from the tropics to the subtropics. This species has high environmental tolerance and is a good space competitor in reef environments. Considering current and future scenarios in the global clima...

journal_title：PeerJ

authors： Durante LM,Cruz ICS,Lotufo TMC

更新日期：2018-05-17 00:00:00

abstract：:Community decline is often linked to anthropogenic activities. Coral reef declines, for example, have been linked to overfishing and climate change, but impacts of coastal development, pollution, and tourism have received increasing attention. Here, we isolated the impact of one little-studied aspect of recreational a...

journal_title：PeerJ

authors： Flynn RL,Forrester GE

更新日期：2019-05-23 00:00:00

abstract：:Transmissible gastroenteritis virus (TGEV), belonging to the coronaviridae family, is the key cause of the fatal diarrhea of piglets and results in many pathological processes. microRNAs (miRNAs) play a key role in the regulation of virus-induced apoptosis. During the process of apoptosis induced by TGEV infection in ...

journal_title：PeerJ

authors： Zhao X,Song X,Bai X,Fei N,Huang Y,Zhao Z,Du Q,Zhang H,Zhang L,Tong D

更新日期：2016-02-04 00:00:00

abstract：:It can be challenging to identify scleractinian corals from the genus Pocillopora Lamarck 1816 in the field because of their large range of inter- and intra-specific morphological variation that co-occur with changes in the physical environment. This task is made more arduous in the context of a depth gradient, where ...

journal_title：PeerJ

authors： De Palmas S,Soto D,Denis V,Ho MJ,Chen CA

更新日期：2018-10-25 00:00:00

abstract：BACKGROUND:Habitat selection and its adaptive outcomes are crucial features for animal life-history strategies. Nevertheless, congruence between habitat preferences and breeding success has been rarely demonstrated, which may result from the single-scale evaluation of animal choices. As habitat selection is a complex m...

journal_title：PeerJ

authors： Jedlikowski J,Brambilla M

更新日期：2017-03-28 00:00:00

abstract：:Organic fertilizer application could have an impact on the nitrogen cycle mediated by microorganisms in arable soils. However, the dynamics of soil ammonia oxidizers and denitrifiers in response to compost addition are less understood. In this study, we examined the effect of four compost application rates (0, 11.25, ...

journal_title：PeerJ

authors： Yang Z,Guan Y,Bello A,Wu Y,Ding J,Wang L,Ren Y,Chen G,Yang W

更新日期：2020-04-21 00:00:00

abstract：:Mechanisms generating and maintaining biodiversity at regional scales may be evaluated by quantifying β-diversity along environmental gradients. Differences in assemblages result in biotic complementarities and redundancies among sites, which may be quantified through multi-dimensional approaches incorporating taxonom...

journal_title：PeerJ

authors： de Fraga R,Ferrão M,Stow AJ,Magnusson WE,Lima AP

更新日期：2018-09-24 00:00:00

abstract：:Conservation initiatives to protect and restore valued species communities in human-dominated landscapes face challenges linked to their potential costs. Conservation easements on private land may represent a cost-effective alternative to land purchase, but long-term costs to monitor and enforce easements, or defend l...

journal_title：PeerJ

authors： Schuster R,Arcese P

更新日期：2015-08-13 00:00:00

abstract：Background:Carbon (C), nitrogen (N) and phosphorus (P) stoichiometric ratios are important indicators of ecosystem function and productivity. However, few studies have assessed the nutrient relationship between plant, litter and soil, and the nutrient stock in different secondary mixed forest types. Methods:We investi...

journal_title：PeerJ

authors： Pang Y,Tian J,Zhao X,Chao Z,Wang Y,Zhang X,Wang D

更新日期：2020-06-03 00:00:00

abstract：BACKGROUND:Staphylococci are commensals of the mucosal surface and skin of humans and animals, but have been implicated in infections such as otitis externa, pyoderma, urinary tract infections and post-surgical complications. Laboratory records provide useful information to help investigate these infections. Therefore,...

journal_title：PeerJ

authors： Qekwana DN,Oguttu JW,Sithole F,Odoi A

更新日期：2017-04-13 00:00:00

abstract：:Previous studies of population genetic structure in Dissostichus eleginoides have shown that oceanographic and geographic discontinuities drive in this species population differentiation. Studies have focused on the genetics of D. eleginoides in the Southern Ocean; however, there is little knowledge of their genetic v...

journal_title：PeerJ

authors： Canales-Aguirre CB,Ferrada-Fuentes S,Galleguillos R,Oyarzun FX,Hernández CE

更新日期：2018-01-16 00:00:00

abstract：:We developed a novel method based on the Fourier analysis of protein molecular surfaces to speed up the analysis of the vast structural data generated in the post-genomic era. This method computes the power spectrum of surfaces of the molecular electrostatic potential, whose three-dimensional coordinates have been eit...

journal_title：PeerJ

authors： Carvalho CS,Vlachakis D,Tsiliki G,Megalooikonomou V,Kossida S

更新日期：2013-10-22 00:00:00

abstract：:As a vector of Xylella fastidiosa (Wells, 1987) in Europe, the meadow spittlebug Philaenus spumarius (Linnaeus, 1758) (Hemiptera, Aphrophoridae) is a species of major concern. Therefore, tools and agents to control this ubiquitous insect that develops and feeds on hundreds of plant species are wanted. We conducted a f...

journal_title：PeerJ

authors： Mesmin X,Chartois M,Genson G,Rossi JP,Cruaud A,Rasplus JY

更新日期：2020-03-24 00:00:00

abstract：:The knowledge on the spatial distribution of soil available water capacity at a regional or national extent is essential, as soil water capacity is a component of the water and energy balances in the terrestrial ecosystem. It controls the evapotranspiration rate, and has a major impact on climate. This paper demonstra...

journal_title：PeerJ

authors： Hong SY,Minasny B,Han KH,Kim Y,Lee K

更新日期：2013-04-23 00:00:00

abstract：Background:The diagnosis of congenital heart defects is challenging, especially for what concerns conotruncal anomalies. Indeed, although the screening techniques of fetal cardiac anomalies have greatly improved, the detection rate of conotruncal anomalies still remains low due to the fact that they are associated with...

journal_title：PeerJ

authors： Dell'Oro S,Verderio M,Incerti M,Mastrolia SA,Cozzolino S,Vergani P

更新日期：2018-04-06 00:00:00

abstract：:To understand the mechanism of photosynthetic inhibition and generation of reactive oxygen species (ROS) in Symbiodinium types under stress, chemicals such as dichlorophenyl dimethylurea (DCMU) are widely used. Moreover, DCMU and recently menthol were used to generate aposymbiotic cnidarian hosts. While the effects of...

journal_title：PeerJ

authors： Wang JT,Keshavmurthy S,Chu TY,Chen CA

更新日期：2017-10-02 00:00:00

abstract：Background:Current and future changes in rainfall amount and frequency may particularly impact annual plants in desert ecosystems. The winter annual Echinops gmelinii Turcz. is widely distributed in the desert habitats of northern China and is a dominant pioneer annual plant following sand stabilization in the Tengger ...

journal_title：PeerJ

authors： Wang Y,Li X,Liu L,Zhao J,Sun J

更新日期：2019-11-29 00:00:00

abstract：:The amphibian skin microbiome has been the focus of recent studies aiming to better understand the role of these microbial symbionts in host defense against disease. However, host-associated microbial communities are complex and dynamic, and changes in their composition and structure can influence their function. Unde...

journal_title：PeerJ

authors： Estrada A,Hughey MC,Medina D,Rebollar EA,Walke JB,Harris RN,Belden LK

更新日期：2019-06-21 00:00:00

abstract：:Epidemiological studies of low prevalence disease problems are often hindered by the high cost of diagnostic testing. The objective of this study was to evaluate PCR screening of both individual and pooled fecal samples from culled dairy cows for the invA gene of Salmonella followed by culture to determine if the sens...

journal_title：PeerJ

authors： Adaska JM,Ekong PS,Clothier KA,Williams DR,Rossitto PV,Lehenbauer TW,Atwill ER,Li X,Aly SS

更新日期：2020-01-15 00:00:00