Abstract：
:Single-celled eukaryotes (protists) are critical players in global biogeochemical cycling of nutrients and energy in the oceans. While their roles as primary producers and grazers are well appreciated, other aspects of their life histories remain obscure due to challenges in culturing and sequencing their natural diversity. Here, we exploit single-cell genomics and metagenomics data from the circumglobal Tara Oceans expedition to analyze the genome content and apparent oceanic distribution of seven prevalent lineages of uncultured heterotrophic stramenopiles. Based on the available data, each sequenced genome or genotype appears to have a specific oceanic distribution, principally correlated with water temperature and depth. The genome content provides hypotheses for specialization in terms of cell motility, food spectra, and trophic stages, including the potential impact on their lifestyles of horizontal gene transfer from prokaryotes. Our results support the idea that prominent heterotrophic marine protists perform diverse functions in ocean ecology.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Seeleuthner Y,Mondy S,Lombard V,Carradec Q,Pelletier E,Wessner M,Leconte J,Mangot JF,Poulain J,Labadie K,Logares R,Sunagawa S,de Berardinis V,Salanoubat M,Dimier C,Kandels-Lewis S,Picheral M,Searson S,Tara Oceans Coordoi
10.1038/s41467-017-02235-3subject
Has Abstractpub_date
2018-01-22 00:00:00pages
310issue
1issn
2041-1723pii
10.1038/s41467-017-02235-3journal_volume
9pub_type
杂志文章abstract：:Phase transitions in amorphous alloys under pressure are an important fundamental problem. Here we report on a first-principles study that reproduces the recently discovered pressure-induced crystallization of amorphous Ce100-xAlx (x<25) alloys and reveals an atomistic transformation mechanism. Contrary to common beli...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms7493
更新日期：2015-03-09 00:00:00
abstract：:Anterior pituitary is critical for endocrine systems. Its hormonal responses to positive and negative regulators are indispensable for homeostasis. For this reason, generating human anterior pituitary tissue that retains regulatory hormonal control in vitro is an important step for the development of cell transplantat...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms10351
更新日期：2016-01-14 00:00:00
abstract：:Lanthanide compounds show much higher energy barriers to magnetic relaxation than 3d-block compounds, and this has led to speculation that they could be used in molecular spintronic devices. Prototype molecular spin valves and molecular transistors have been reported, with remarkable experiments showing the influence ...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms6243
更新日期：2014-10-13 00:00:00
abstract：:Dopamine regulates reward, cognition, and locomotor functions. By mediating rapid reuptake of extracellular dopamine, the dopamine transporter is critical for spatiotemporal control of dopaminergic neurotransmission. Here, we use super-resolution imaging to show that the dopamine transporter is dynamically sequestrate...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-017-00790-3
更新日期：2017-09-29 00:00:00
abstract：:By electrochemically coupling microbial and abiotic catalysts, bioelectrochemical systems such as microbial electrolysis cells and microbial electrosynthesis systems synthesize energy-rich chemicals from energy-poor precursors with unmatched efficiency. However, to circumvent chemical incompatibilities between the mic...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-018-04707-6
更新日期：2018-06-11 00:00:00
abstract：:While free electrons in metals respond to ultrafast excitation with refractive index changes on femtosecond time scales, typical relaxation mechanisms occur over several picoseconds, governed by electron-phonon energy exchange rates. Here, we propose tailoring these intrinsic rates by engineering a non-uniform electro...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-10840-7
更新日期：2019-07-04 00:00:00
abstract：:The mechanism of action of artemisinin and its derivatives, the most potent of the anti-malarial drugs, is not completely understood. Here we present an unbiased chemical proteomics analysis to directly explore this mechanism in Plasmodium falciparum. We use an alkyne-tagged artemisinin analogue coupled with biotin to...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms10111
更新日期：2015-12-22 00:00:00
abstract：:Saturn's largest moon Titan has a substantial nitrogen-methane atmosphere, with strong seasonal effects, including formation of winter polar vortices. Following Titan's 2009 northern spring equinox, peak solar heating moved to the northern hemisphere, initiating south-polar subsidence and winter polar vortex formation...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-017-01839-z
更新日期：2017-11-21 00:00:00
abstract：:Cytokinesis mediates the physical separation of dividing cells and, in 3D epithelia, provides a spatial landmark for lumen formation. Here, we unravel an unexpected role in cytokinesis for proteins of the intraflagellar transport (IFT) machinery, initially characterized for their ciliary role and their link to polycys...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-017-01479-3
更新日期：2017-12-04 00:00:00
abstract：:TNF-like ligand 1 A (TL1A) and death receptor 3 (DR3) are a ligand-receptor pair involved in the pathogenesis of inflammatory bowel disease. Group 3 innate lymphoid cells (ILC3s) regulate intestinal immunity and highly express DR3. Here, we report that activation of DR3 signaling by an agonistic anti-DR3 antibody incr...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-11304-8
更新日期：2019-07-29 00:00:00
abstract：:Arabinosyltransferase B (EmbB) belongs to a family of membrane-bound glycosyltransferases that build the lipidated polysaccharides of the mycobacterial cell envelope, and are targets of anti-tuberculosis drug ethambutol. We present the 3.3 Å resolution single-particle cryo-electron microscopy structure of Mycobacteriu...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-17202-8
更新日期：2020-07-07 00:00:00
abstract：:Self-repairable materials strive to emulate curable and resilient biological tissue; however, their performance is currently insufficient for commercialization purposes because mending and toughening are mutually exclusive. Herein, we report a carbonate-type thermoplastic polyurethane elastomer that self-heals at 35 °...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-021-20931-z
更新日期：2021-01-27 00:00:00
abstract：:Streptomycetes are notable for their complex life cycle and production of most clinically important antibiotics. A key factor that controls entry into development and the onset of antibiotic production is the 68-residue protein, BldC. BldC is a putative DNA-binding protein related to MerR regulators, but lacks coiled-...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-018-03576-3
更新日期：2018-03-19 00:00:00
abstract：:During bacterial cell division, the tubulin-homolog FtsZ forms a ring-like structure at the center of the cell. This Z-ring not only organizes the division machinery, but treadmilling of FtsZ filaments was also found to play a key role in distributing proteins at the division site. What regulates the architecture, dyn...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-13702-4
更新日期：2019-12-17 00:00:00
abstract：:Tropical carbon emissions are largely derived from direct forest clearing processes. Yet, emissions from drought-induced forest fires are, usually, not included in national-level carbon emission inventories. Here we examine Brazilian Amazon drought impacts on fire incidence and associated forest fire carbon emissions ...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-017-02771-y
更新日期：2018-02-13 00:00:00
abstract：:A disturbance of reactive oxygen species (ROS) homeostasis may cause the pathogenesis of many diseases. Inspired by natural photosynthesis, this work proposes a photo-driven H2-evolving liposomal nanoplatform (Lip NP) that comprises an upconversion nanoparticle (UCNP) that is conjugated with gold nanoparticles (AuNPs)...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-14413-x
更新日期：2020-01-27 00:00:00
abstract：:Due to the generally delocalized nature of molecular valence orbitals, valence-shell spectroscopies do not usually allow to specifically target a selected atom in a molecule. However, in X-ray electron spectroscopy, the photoelectron momentum is large and the recoil angular momentum transferred to the molecule is larg...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms4816
更新日期：2014-05-09 00:00:00
abstract：:Alteration of the gut microbiota has been associated with different gastrointestinal disorders. Normobiosis restoration by faecal microbiota transplantation (FMT) is considered a promising therapeutic approach, even if the mechanisms underlying its efficacy are at present largely unknown. Here we sought to elucidate t...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-018-07359-8
更新日期：2018-12-05 00:00:00
abstract：:Visualization and exploration of high-dimensional data is a ubiquitous challenge across disciplines. Widely used techniques such as principal component analysis (PCA) aim to identify dominant trends in one dataset. However, in many settings we have datasets collected under different conditions, e.g., a treatment and a...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-018-04608-8
更新日期：2018-05-30 00:00:00
abstract：:The availability of multiple datasets comprising genome-scale RNAi viability screens in hundreds of diverse cancer cell lines presents new opportunities for understanding cancer vulnerabilities. Integrated analyses of these data to assess differential dependency across genes and cell lines are challenging due to confo...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-018-06916-5
更新日期：2018-11-02 00:00:00
abstract：:In most metazoan nuclei, heterochromatin is located at the nuclear periphery in contact with the nuclear lamina, which provides mechanical stability to the nucleus. We show that in cultured cells, chromatin decompaction by the nucleosome binding protein HMGN5 decreases the sturdiness, elasticity and rigidity of the nu...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms7138
更新日期：2015-01-22 00:00:00
abstract：:In the lead-up to the Cretaceous/Paleogene mass extinction, dinosaur diversity is argued to have been either in long-term decline, or thriving until their sudden demise. The latest Cretaceous (Campanian-Maastrichtian [83-66 Ma]) of North America provides the best record to address this debate, but even here diversity ...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-08997-2
更新日期：2019-03-06 00:00:00
abstract：:Nano-ordered intermetallic compounds have generated great interest in fuel cell applications. However, the synthesis of non-preciousearly transition metal intermetallic nanoparticles remains a formidable challenge owing to the extremely oxyphilic nature and very negative reduction potentials. Here, we have successfull...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-12509-7
更新日期：2019-10-04 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Nature communications
pub_type： 杂志文章,已发布勘误
doi：10.1038/s41467-020-18510-9
更新日期：2020-09-08 00:00:00
abstract：:Common fragile sites (CFSs) are chromosome regions prone to breakage upon replication stress known to drive chromosome rearrangements during oncogenesis. Most CFSs nest in large expressed genes, suggesting that transcription could elicit their instability; however, the underlying mechanisms remain elusive. Genome-wide...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-13674-5
更新日期：2019-12-13 00:00:00
abstract：:Global-scale nitrogen budgets developed to quantify anthropogenic impacts on the nitrogen cycle do not explicitly consider nitrate stored in the vadose zone. Here we show that the vadose zone is an important store of nitrate that should be considered in future budgets for effective policymaking. Using estimates of gro...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-017-01321-w
更新日期：2017-11-10 00:00:00
abstract：:Optogenetics enables manipulation of biological processes with light at high spatio-temporal resolution to control the behavior of cells, networks, or even whole animals. In contrast to the performance of excitatory rhodopsins, the effectiveness of inhibitory optogenetic tools is still insufficient. Here we report a t...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-018-07038-8
更新日期：2018-11-05 00:00:00
abstract：:Enhancement of optical emission on plasmonic nanostructures is intrinsically limited by the distance between the emitter and nanostructure surface, owing to a tightly-confined and exponentially-decaying electromagnetic field. This fundamental limitation prevents efficient application of plasmonic fluorescence enhancem...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-16813-5
更新日期：2020-06-10 00:00:00
abstract：:The ability to quickly spread a liquid across a surface and form a film is fundamental for a diverse range of technological processes, including printing, painting and spraying. Here we show that liquid dielectrophoresis or electrowetting can produce wetting on normally non-wetting surfaces, without needing modificati...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms2619
更新日期：2013-01-01 00:00:00
abstract：:LPMO (lytic polysaccharide monooxygenase) represents a unique paradigm of cellulosic biomass degradation by an oxidative mechanism. Understanding the role of LPMO in deconstructing crystalline cellulose is fundamental to the enzyme's biological function and will help to specify the use of LPMO in biorefinery applicati...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-017-01028-y
更新日期：2017-10-12 00:00:00
