Abstract:
:This corrects the article DOI: 10.1038/srep45235.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Wu J,Hu S,Chen Y,Li Z,Zhang J,Yuan H,Shi Q,Shao N,Ying Xdoi
10.1038/srep46913subject
Has Abstractpub_date
2017-12-22 00:00:00pages
46913issn
2045-2322pii
srep46913journal_volume
7pub_type
杂志文章,已发布勘误abstract::Gaucher disease (GD) is a rare inherited metabolic disease caused by pathogenic variants in the GBA1 gene. So far, the pathomechanism of GD was investigated mainly in animal models. In order to delineate the molecular changes in GD cells we analysed gene expression profile in cultured skin fibroblasts from GD patients...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-42584-1
更新日期:2019-04-15 00:00:00
abstract::Nanomaterials can be incorporated in the synthesis of membrane to obtain mixed-matrix membrane with marked improvement in properties and performance. However, stability and dispersion of the nanomaterials in the membrane matrix, as well as the need to use high ratio of nanomaterials for obvious improvement of membrane...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-38060-x
更新日期:2019-02-04 00:00:00
abstract::To effectively manage a watershed and successfully restore a river system, it is very important to assess the toxicity of sediments and identify the substances causing the toxicity. Seventy-six sediments collected in the Haihe River Basin (HRB) in China were screened for acute toxicity using Chironomus dilutus. We fou...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-01631-5
更新日期:2017-05-03 00:00:00
abstract::Junction-less nanowire transistors are being investigated to solve short channel effects in future CMOS technology. Here we demonstrate 8 nm diameter silicon nanowire junction-less transistors with metallic doping densities which demonstrate clear 1D electronic transport characteristics. The 1D regime allows excellent...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-03138-5
更新日期:2017-06-07 00:00:00
abstract::Congenital glaucoma (CG) is a heterogeneous, inherited and severe optical neuropathy that originates from maldevelopment of the anterior segment of the eye. To identify new disease genes, we performed whole-exome sequencing of 26 unrelated CG patients. In one patient we identified two rare, recessive and hypermorphic ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep46175
更新日期:2017-04-11 00:00:00
abstract::The aim of this study is to identify subsets of T cells differentially represented in the circulation of patients with psoriatic arthritis and to evaluate the possibility that they can recirculate between peripheral blood and the inflamed joints. We analyzed the phenotype and cytokine expression in circulating CD8+ an...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-47310-5
更新日期:2019-07-26 00:00:00
abstract::Marine pollution is a significant issue in recent decades, with the increase in industries and their waste harming the environment and ecosystems. Notably, the rise in shellfish industries contributes to tons of shellfish waste composed of up to 58% chitin. Chitin, the second most ample polymer next to cellulose, is i...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-68772-y
更新日期:2020-07-17 00:00:00
abstract::Although it has been reported that uterine signal transducer and activator of transcription 3 (STAT3) is essential for embryo implantation, the exact roles of uterine epithelial and stromal STAT3 on embryo implantation have not been elucidated. To address this issue, we generated Stat3-floxed/Ltf-iCre (Stat3-eKO), Sta...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-72640-0
更新日期:2020-09-23 00:00:00
abstract::Despite extensive efforts in studying radioactive aerosols, including the transmission of radionuclides in different chemical matrices throughout the body, the internal organ-specific radiation dose due to inhaled radioactive aerosols has largely relied on experimental deposition data and simplified human phantoms. Co...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-54040-1
更新日期:2019-11-25 00:00:00
abstract::CoO nanocrystal/graphene nanosheets (GNS) composites, consisting of a triangular CoO nanocrystal of 2~20 nm on the surface of GNS, are synthesized by a mild synthetic method. First, cobalt acetate tetrahydrate is recrystallized in the alcohol solution at a low temperature. Then, graphene oxide mixed with cobalt-precur...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep10017
更新日期:2015-05-11 00:00:00
abstract::In general, the poultry industry uses 0.5-1 ppm chlorine solution in the meat sanitization process. However, chlorine can react with organic material and produce halogenated organic compounds, notably chloroform, which causes bladder and rectal cancer in humans. For this reason, many industries try to avoid chlorine. ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-58199-w
更新日期:2020-01-31 00:00:00
abstract::Repetitive transcranial magnetic stimulation (rTMS) has been proposed as a tinnitus treatment option. Promising results have been obtained by consecutive stimulation of lateral frontal and auditory brain regions. We investigated a combined stimulation paradigm targeting the anterior cingulate cortex (ACC) with double ...
journal_title:Scientific reports
pub_type: 杂志文章,随机对照试验
doi:10.1038/srep18028
更新日期:2015-12-15 00:00:00
abstract::The first-ever study of nickel selenide materials as efficient anode materials for Na-ion rechargeable batteries is conducted using the electrospinning process. NiSe2-reduced graphene oxide (rGO)-C composite nanofibers are successfully prepared via electrospinning and a subsequent selenization process. The electrospun...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep23338
更新日期:2016-03-21 00:00:00
abstract::Electroencephalographic hyperscanning was used to investigate interbrain synchronization patterns in dyads of participants interacting through speech. Results show that brain oscillations are synchronized between listener and speaker during oral narratives. This interpersonal synchronization is mediated in part by a l...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-04464-4
更新日期:2017-06-23 00:00:00
abstract::The widely accepted multiple-hit hypothesis of carcinogenesis states that cancers arise after several successive events. However, no consensus has been reached on the quantity and nature of these events, although "driver" mutations or epimutations are considered the most probable candidates. By using the largest publi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-12448-7
更新日期:2017-09-22 00:00:00
abstract::Achieving 180° magnetization reversal with an electric field rather than a current or magnetic field is a fundamental challenge and represents a technological breakthrough towards new memory cell designs. Here we propose a mesoscale morphological engineering approach to accomplishing full 180° magnetization reversals ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep07507
更新日期:2014-12-16 00:00:00
abstract::Apterous (Ap), the best studied LIM-homeodomain transcription factor in Drosophila, cooperates with the cofactor Chip (Chi) to regulate transcription of specific target genes. Although Ap regulates various developmental processes, its function in the adult brain remains unclear. Here, we report that Ap and Chi in the ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37255
更新日期:2016-11-17 00:00:00
abstract::Single-photon emitters with stable and uniform photoluminescence properties are important for quantum technology. However, in many cases, colour centres in diamond exhibit spectral diffusion and photoluminescence intensity fluctuation. It is therefore essential to investigate the dynamics of colour centres at the sing...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep12244
更新日期:2015-07-23 00:00:00
abstract::Biological control mechanisms of plant diseases have been intensively studied. However, how plant pathogens respond to and resist or alleviate biocontrol agents remains largely unknown. In this study, a comparative transcriptome analysis was performed to elucidate how the pathogen of sclerotinia stem rot, Sclerotinia ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-69434-9
更新日期:2020-07-28 00:00:00
abstract::OVGP1 is the major non-serum glycoprotein in the oviduct fluid at the time of fertilization and early embryo development. Its activity differs among species. Here, we show that the C-terminal region of recombinant OVGP1 regulates its binding to the extracellular zona pellucida and affects its activity during fertiliza...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep32556
更新日期:2016-09-07 00:00:00
abstract::The stochastic tunneling-basin hopping method (STUN-BH) was utilized to obtain the most stable peptide S7 configuration (Ac-Ser-Ser-Phe-Pro-Gln-Pro-Asn-CONH2) adsorbed on Au(111) facet. After the most stable S7 configuration was found, molecular dynamics (MD) simulation was conducted to investigate the thermal stabili...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-59144-7
更新日期:2020-02-07 00:00:00
abstract::The purpose of this study was to find the circulating microRNAs (miRNAs) co-related with the severity of coronary artery calcification (CAC), and testify whether the selected miRNAs could reflect the obstructive coronary artery disease in symptomatic patients. Patients with chest pain and moderated risk for coronary a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep16099
更新日期:2015-11-05 00:00:00
abstract::Pond-dwelling cyclic parthenogens are often proposed to be highly vagile. However, the Holarctic biogeography of parthenogens has been hampered by very limited sampling in the eastern Palearctic. Here we examine the geographic boundaries, diversity, and connectivity across the Palearctic for the Daphnia curvirostris c...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-43281-9
更新日期:2019-05-02 00:00:00
abstract::Mobility of people and goods during the Upper Paleolithic has proven difficult to reconstruct given the relative rareness of remains. Nevertheless, archaeological contexts like the Late Pleistocene horizon of Borsuka Cave (Southern Poland) represent a unique opportunity to explore patterns of objects' transportation a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-67017-2
更新日期:2020-06-25 00:00:00
abstract::Modification of lattice thermal conductivity (κL) of a solid by means of hydrostatic pressure (P) has been a crucially interesting approach that targets a broad range of advanced materials from thermoelectrics and thermal insulators to minerals in mantle. Although it is well documented knowledge that thermal conductiv...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29801
更新日期:2016-07-19 00:00:00
abstract::A cross-correlative precession electron diffraction - atom probe tomography investigation of Cr segregation in a Fe(Cr) nanocrystalline alloy was undertaken. Solute segregation was found to be dependent on grain boundary type. The results of which were compared to a hybrid Molecular Dynamics and Monte Carlo simulation...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep34642
更新日期:2016-10-06 00:00:00
abstract::Liver repopulation by transplanted hepatocytes has not been achieved previously in a normal liver microenvironment. Here we report that adult rat hepatocytes transduced ex vivo with a lentivirus expressing a human YapERT2 fusion protein (hYapERT2) under control of the hepatocyte-specific transthyretin (TTR) promoter r...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep19275
更新日期:2016-01-14 00:00:00
abstract::Myosin phosphatase (MP) holoenzyme is a protein phosphatase-1 (PP1) type Ser/Thr specific enzyme that consists of a PP1 catalytic (PP1c) and a myosin phosphatase target subunit-1 (MYPT1). MYPT1 is an ubiquitously expressed isoform and it targets PP1c to its substrates. We identified the protein arginine methyltransfer...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep40590
更新日期:2017-01-11 00:00:00
abstract::The effects of climate change on the taste and textural attributes of foods remain largely unknown, despite much public interest. On the basis of 30-40 years of records, we provide evidence that the taste and textural attributes of apples have changed as a result of recent global warming. Decreases in both acid concen...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02418
更新日期:2013-01-01 00:00:00
abstract::Respiratory syncytial virus (RSV) is a major cause of diseases of the respiratory tract in young children and babies, being mainly associated with bronchiolitis. RSV infection occurs primarily in pulmonary epithelial cells and, once infection is established, an immune response is triggered and neutrophils are recruite...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-32576-y
更新日期:2018-09-21 00:00:00