The intracellular association of B700 and B50 murine melanoma antigens and their role in tumor rejection.

abstract：:The distance of nerve invasion is an important prognostic factor in pancreatic cancer. The extracellular matrix (ECM) of nerve, mainly composed of laminin, collagen IV and anchoring fibrils, might affect nerve invasion. However, this relationship has not been demonstrated. Our study aimed at discovering the promoting ...

journal_title：International journal of cancer

authors： Mitsunaga S,Fujii S,Ishii G,Kinoshita T,Hasebe T,Aoyagi K,Sasaki H,Ochiai A

更新日期：2010-08-15 00:00:00

abstract：:The purpose of this study was to assess the relationship between progression-free survival (PFS) in patients treated with DFMO + PCV (procarbazine, CCNU, vincristine) chemotherapy for malignant gliomas with tumor cell ornithine decarboxylase (ODC) activity. Formalin-fixed slides were obtained for study patients with a...

journal_title：International journal of cancer

authors： Levin VA,Jochec JL,Shantz LM,Aldape KD

更新日期：2007-11-15 00:00:00

abstract：:Progress against cancer through prevention and treatment is often measured by survival statistics only instead of analyzing trends in incidence, survival and mortality simultaneously because of interactive influences. This study combines these parameters of major cancers to provide an overview of the progress achieved...

journal_title：International journal of cancer

authors： Karim-Kos HE,Kiemeney LA,Louwman MW,Coebergh JW,de Vries E

更新日期：2012-06-15 00:00:00

abstract：:Cancer blood vessels consist of two interacting types of cells: inner lining endothelial cells (ECs) and surrounding perivascular cells (pericytes, vascular smooth muscle cells or mural cells). PDGFRbeta(CD140b)+ progenitor perivascular cells (PPC) can differentiate into pericytes and regulate vessel stability and vas...

journal_title：International journal of cancer

authors： Mancuso P,Martin-Padura I,Calleri A,Marighetti P,Quarna J,Rabascio C,Braidotti P,Bertolini F

更新日期：2011-09-15 00:00:00

abstract：:A panel of 24 healthy seropositive donors have been followed prospectively over a period of 15 months and monitored (1) for the level of EB virus shedding in the throat by means of a sensitive cord-blood transformation assay; (2) for the level of virus-infected B cells in the blood via a new in vitro protocol where "s...

journal_title：International journal of cancer

authors： Yao QY,Rickinson AB,Epstein MA

更新日期：1985-01-15 00:00:00

abstract：:Cigarette smoking and alcohol consumption were examined as potential risk factors in a case-control study of primary liver cancer (PLC). A total of 165 PLC cases and 465 matched controls from several US hospitals were studied. A weak but statistically significant (p less than 0.05) dose-response relationship was obser...

journal_title：International journal of cancer

authors： Yu H,Harris RE,Kabat GC,Wynder EL

更新日期：1988-09-15 00:00:00

abstract：:Loss of heterozygosity (LOH) at the site of the retinoblastoma (RB1) gene, at 13q14, has been shown to occur in a high proportion of ovarian cancer patients. Based on this, RB1 gene inactivation was studied in primary tumor cells from 15 patients with ovarian cancer. Structural changes as well as expression of the RB1...

journal_title：International journal of cancer

authors： Liu Y,Heyman M,Wang Y,Falkmer U,Hising C,Székely L,Einhorn S

更新日期：1994-09-01 00:00:00

abstract：:We evaluated the associations of such lifestyle factors as alcohol drinking, coffee consumption and medical history with risk of death from pancreatic cancer in a large-scale prospective cohort study [the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC study)] in Japan. Subjects were 110,792 (46,4...

journal_title：International journal of cancer

authors： Lin Y,Tamakoshi A,Kawamura T,Inaba Y,Kikuchi S,Motohashi Y,Kurosawa M,Ohno Y

更新日期：2002-06-10 00:00:00

abstract：:Using nationwide Danish registries we examined the long-term risk of cervical cancer in women diagnosed with cervical intraepithelial neoplasia grade 3 (CIN3) (including adenocarcinoma in situ (AIS)) on the cone compared to women with a normal cytology test. Initially, we identified women born 1918-1990, who were reco...

journal_title：International journal of cancer

authors： Sand FL,Frederiksen K,Munk C,Jensen SM,Kjaer SK

更新日期：2018-05-01 00:00:00

abstract：:Exosomal noncoding RNAs (ncRNAs) have unique expression profiles reflecting the characteristics of a tumor, and their role in tumor progression and metastasis is emerging. However, the significance of circulating exosomal ncRNAs in the prognosis of hepatocellular carcinoma (HCC) remains to be elucidated. We therefore ...

journal_title：International journal of cancer

authors： Lee YR,Kim G,Tak WY,Jang SY,Kweon YO,Park JG,Lee HW,Han YS,Chun JM,Park SY,Hur K

更新日期：2019-03-15 00:00:00

abstract：:We sought to analyze utilization and survival outcomes of cytoreductive nephrectomy (CN) in patients with metastatic renal cell carcinoma (RCC) before and after introduction of targeted therapy. We identified patients with metastatic RCC between 1993 and 2010 in the SEER registry and examined temporal trends in utiliz...

journal_title：International journal of cancer

authors： Conti SL,Thomas IC,Hagedorn JC,Chung BI,Chertow GM,Wagner TH,Brooks JD,Srinivas S,Leppert JT

更新日期：2014-05-01 00:00:00

abstract：:The monoclonal antibody trastuzumab has brought survival benefit to patients with advanced gastric cancer (AGC) that have human epidermal growth factor receptor 2 (HER2) over expression or amplification. This study was designed to compare the clinical outcomes of HER2-negative and HER2-positive AGC patients with or wi...

journal_title：International journal of cancer

authors： Qiu MZ,Li Q,Wang ZQ,Liu TS,Liu Q,Wei XL,Jin Y,Wang DS,Ren C,Bai L,Zhang DS,Wang FH,Li YH,Xu RH

更新日期：2014-05-15 00:00:00

abstract：:With low cure rates but increasing diverse treatment options that provide variable remission times, ovarian cancer is increasingly being recognized as a chronic disease. This reality indicates the need for a better understanding of factors influencing disease progression. In a previous global analysis of gene expressi...

journal_title：International journal of cancer

authors： Ouellet V,Le Page C,Guyot MC,Lussier C,Tonin PN,Provencher DM,Mes-Masson AM

更新日期：2006-11-01 00:00:00

abstract：:The mass screening (MS) of neuroblastoma has been undertaken in Japan by measuring urinary catecholamine metabolites in infants at the age of 6 months. To clarify the biological characteristics of MS-positive (MS+) tumors in infants and MS-negative (MS-)/late-presenting tumors in young children, metaphase cytogenetic ...

journal_title：International journal of cancer

authors： Kaneko Y,Kobayashi H,Maseki N,Nakagawara A,Sakurai M

更新日期：1999-01-05 00:00:00

abstract：:CD44 is a transmembrane glycoprotein that binds hyaluronan, extracellular matrix proteins and growth factors. Multiple isoforms of CD44 are generated by alternative splicing of 10 separate exons (V1-V10). Expression of the variable exons has been correlated with tumour progression and metastasis in a range of cell typ...

journal_title：International journal of cancer

authors： Hudson DL,Speight PM,Watt FM

更新日期：1996-05-16 00:00:00

abstract：:Melanoma is a highly malignant and increasingly common neoplasm. Because metastatic melanoma remains incurable, new treatment approaches are needed. Immunoliposomes have been previously shown to enhance the selective localization of immunoliposome-entrapped drugs to solid tumors with improvements in the therapeutic in...

journal_title：International journal of cancer

authors： Pagnan G,Montaldo PG,Pastorino F,Raffaghello L,Kirchmeier M,Allen TM,Ponzoni M

更新日期：1999-04-12 00:00:00

abstract：:Tumor growth and metastasis of lacZ-transduced murine lymphoma ESbL cells inoculated into syngeneic DBA/2 mice are characterized by a transient plateau phase with a constant tumor diameter and low metastatic load, indicating a host response against the tumor. Here we show that endothelial cells participate in a T-cell...

journal_title：International journal of cancer

authors： Rocha M,Krüger A,Van Rooijen N,Schirrmacher V,Umansky V

更新日期：1995-11-03 00:00:00

abstract：:Imbalance in the Kb and Db region encoded molecules is observed in Lewis lung carcinoma clones. The uncloned metastatic population and the D122 high-metastatic clone show no expression of H-2Kb products, while the nonmetastatic A9 clone expresses Kb products. Twenty-nine new subclones of 3LL and A9 were analyzed for D...

journal_title：International journal of cancer

authors： Eisenbach L,Segal S,Feldman M

更新日期：1983-07-15 00:00:00

abstract：:Epstein-Barr virus (EBV) is present in Reed-Sternberg (RS) cells of a substantial proportion of Hodgkin's lymphoma cases. Most EBV-positive cases are also MHC class I-positive, whereas the majority of EBV-negative cases lack detectable levels of MHC class I expression. Application of the SAGE technique has led to the ...

journal_title：International journal of cancer

authors： Van den Berg A,Visser L,Eberwine J,Dadvand L,Poppema S

更新日期：2000-05-15 00:00:00

abstract：:Tissue recombinants (TRs) composed of mouse urogenital mesenchyme (mUGM) plus an immortalized nontumorigenic human prostatic epithelial cell line (BPH-1) were grown under the kidney capsule of male athymic nude mice under different hormonal conditions. The objectives were to determine temporal plasma concentrations of...

journal_title：International journal of cancer

authors： Ricke WA,Ishii K,Ricke EA,Simko J,Wang Y,Hayward SW,Cunha GR

更新日期：2006-05-01 00:00:00

abstract：:The insulin-like growth factors (IGF-I and IGF-II) play a key role in cellular proliferation and are involved in cellular transformation. The expression of the IGF-I receptor has been demonstrated in a variety of human tumor cell lines including ovarian cancer cells. Phosphorothioate antisense oligodeoxynucleotides (S...

journal_title：International journal of cancer

authors： Müller M,Dietel M,Turzynski A,Wiechen K

更新日期：1998-08-12 00:00:00

abstract：:Although thyroid cancer is suspected to have a nutritional etiology, prospective studies examining the relationship between diet and thyroid cancer are lacking. During 1996-1997, NIH-AARP Diet and Health Study participants, ages 51-72 years, completed a 37-item food frequency questionnaire about diet at ages 12-13 yea...

journal_title：International journal of cancer

authors： Braganza MZ,Potischman N,Park Y,Thompson FE,Hollenbeck AR,Kitahara CM

更新日期：2015-11-15 00:00:00

abstract：:1D10 is a previously described antibody that binds to cells from a majority of B-cell malignancies. The current studies were designed to further evaluate the antigen specificity of 1D10 and its potential as an immunotherapeutic agent. Studies with transfectants and immunoprecipitation demonstrated that 1D10 recognizes...

journal_title：International journal of cancer

authors： Kostelny SA,Link BK,Tso JY,Vasquez M,Jorgensen BH,Wang H,Hall WC,Weiner GJ

更新日期：2001-08-15 00:00:00

abstract：:Cells of the human lymphoblastoid non-producer line Raji were cloned in soft agar. Individual colonies were isolated and analyzed for their inducibility of the Epstein-Barr virus-associated early antigen (EA). The induction of EA by the tumor promoter TPA varied among the different cell clones. Clones with very high a...

journal_title：International journal of cancer

authors： Bister K,Yamamoto N,zur Hausen H

更新日期：1979-06-15 00:00:00

abstract：:Persistent infection with high-risk human papillomavirus (HPV) is central to cervical carcinogenesis. Certain high-risk types, such as HPV16, may be more persistent than other HPV types, and type-specific HPV persistence may differ by HIV serostatus. This study evaluated the association between HPV type and clearance ...

journal_title：International journal of cancer

authors： Koshiol JE,Schroeder JC,Jamieson DJ,Marshall SW,Duerr A,Heilig CM,Shah KV,Klein RS,Cu-Uvin S,Schuman P,Celentano D,Smith JS

更新日期：2006-10-01 00:00:00

abstract：:It has been established that the Hedgehog (Hh) and epithelial-mesenchymal transition (EMT) signals act on morphogenesis of embryonic and adult tissues. Recently, both signals have been involved in tumor malignancy. However, little is known as to whether Hh and EMT signals act on normal and malignant epithelial cells i...

journal_title：International journal of cancer

authors： Isohata N,Aoyagi K,Mabuchi T,Daiko H,Fukaya M,Ohta H,Ogawa K,Yoshida T,Sasaki H

更新日期：2009-09-01 00:00:00

abstract：:Metabolic syndrome (MetS) and its components may link to pancreatic cancer risk; however, current epidemiological evidence is limited, and the potential mechanisms underlying the associations remain unclear. To investigate this, we carried out this prospective cohort study of 474 929 participants without a diagnosis o...

journal_title：International journal of cancer

authors： Xia B,He Q,Pan Y,Gao F,Liu A,Tang Y,Chong C,Teoh AYB,Li F,He Y,Zhang C,Yuan J

更新日期：2020-12-15 00:00:00

abstract：:Epigenetic inactivation by aberrant DNA methylation has been reported for many microRNA genes in various human malignancies. However, relatively little is known about microRNA gene methylation in hepatocellular carcinoma (HCC). Therefore, a systematic screen for identification of aberrantly hypermethylated microRNA ge...

journal_title：International journal of cancer

authors： Anwar SL,Albat C,Krech T,Hasemeier B,Schipper E,Schweitzer N,Vogel A,Kreipe H,Lehmann U

更新日期：2013-08-01 00:00:00

abstract：:Prostate stem cell antigen (PSCA) and prostate-specific antigen (PSA) are overexpressed in most prostate cancers. PSCA- and PSA-derived, HLA-A2 binding peptides are specific targets for T-cell responses in vitro. A phase I/II trial was performed to demonstrate feasibility, safety and induction of antigen-specific immu...

journal_title：International journal of cancer

authors： Thomas-Kaskel AK,Zeiser R,Jochim R,Robbel C,Schultze-Seemann W,Waller CF,Veelken H

更新日期：2006-11-15 00:00:00

abstract：:Biopsies of 13 penile cancers (PC), from patients living in regions of Uganda with a high incidence of genital cancers, were studied for the presence, molecular characteristics and physical state of DNA related to that of human papillomavirus (HPV) types 6, 11, 16, 18, 31 and 33. HPV DNA sequences were detected in all...

journal_title：International journal of cancer

authors： Tornesello ML,Buonaguro FM,Beth-Giraldo E,Kyalwazi SK,Giraldo G

更新日期：1992-06-19 00:00:00