Introduction of Adonis aestivalis as a new source of effective cytotoxic cardiac glycoside.

abstract：:This article presents the very first phytochemical investigation on new species Tripleurospermum insularum Inceer & Hayırlıoglu-Ayaz. The volatile profile of odorous parts of the plant was analysed by GC/MS, and compounds were identified in headspace and essential oil obtained from aerial parts, representing 70.81% an...

journal_title：Natural product research

authors： Ćavar Zeljković S,Ayaz FA,Inceer H,Hayirlioglu-Ayaz S,Colak N

更新日期：2015-02-01 00:00:00

abstract：:The investigation on the stems and leaves of Clausena lenis led to the isolation of a previously undescribed carbazole alkaloid, clausenalenine A (1), along with seven known analogues (2-8). The structure of 1 was elucidated based on comprehensive spectroscopic analyses and the known compounds were identified by compa...

journal_title：Natural product research

authors： Yan G,Li YJ,Zhao YY,Guo JM,Zhang WH,Zhang MM,Fu YH,Liu YP

更新日期：2019-09-16 00:00:00

abstract：:Six new compounds, colletobredins A-D (1-4) and colletomelleins A and B (5 and 6), along with 12 previously identified compounds, were isolated from the culture broth of Colletotrichum aotearoa BCRC 09F0161, a fungal endophyte residing in the leaves of an endemic Formosan plant Bredia oldhamii Hook. f. (Melastomatacea...

journal_title：Natural product research

authors： Hsiao Y,Cheng MJ,Chang HS,Wu MD,Hsieh SY,Liu TW,Lin CH,Yuan GF,Chen IS

更新日期：2016-01-01 00:00:00

abstract：:The serotonin (5-hydroxytryptamine) type 3 receptor is an important target in the control of digestive dysfunction such as anorexia and bulimia, and 5-HT3 receptor antagonists are effective against eating disorder and the early-phase chemotherapy and radiotherapy evoked vomiting. Our previous research of Valeriana jat...

journal_title：Natural product research

authors： Wang LX,Chen HL,Yan HL,Tang F,Zhang H,Li HX,Ye Q,Peng C,Tan YZ

更新日期：2019-09-10 00:00:00

abstract：:This study is designed to examine the chemical composition and antioxidant activity of the essential oil of Vitex megapotamica. Gas chromatography-mass spectrometry analysis resulted in the detection of 27 components, representing 92.36% of the total oil composition. The main components in the oil were butylated hydro...

journal_title：Natural product research

authors： de Brum TF,Boligon AA,Frohlich JK,Schwanz TG,Zadra M,Piana M,Froeder AL,Athayde ML

更新日期：2013-04-01 00:00:00

abstract：:The cytotoxicity of six ent-kaurene diterpenoids isolated from the leaves of Isodon japonica (Burm.f.) Hara var. galaucocalyx (maxin) Hara was evaluated against three human tumour HepG2, GLC-82 and HL-60 cell lines through SRB assay, and their DNA damage potential (against HepG2 cell line) was assessed by comet assay....

journal_title：Natural product research

authors： Ding L,Zhou Q,Wang L,Wang W,Zhang S,Liu B

更新日期：2011-09-01 00:00:00

abstract：:A new 20-membered macrolide named as levantilide C was isolated from the Micromonospora strain FIM07-0019 recovered from shallow coastal waters near the island of Chiloe, Chile. The chemical structure of levantilide C was elucidated on the basis of one- and two-dimensional NMR analysis. Two known indole derivatives we...

journal_title：Natural product research

authors： Fei P,Chuan-Xi W,Yang X,Hong-Lei J,Lu-Jie C,Uribe P,Bull AT,Goodfellow M,Hong J,Yun-Yang L

更新日期：2013-08-01 00:00:00

abstract：:Phytochemical reinvestigation on the whole plants of Derris laxiflora Benth. afforded two new diprenylated flavanones, derriflavanones B and C (1-2), together with thirty-two known compounds, including sixteen flavonoids (3-18), eleven aromatic compounds (19-29), and five chlorophylls (30-34). All known compounds were...

journal_title：Natural product research

authors： Huang HC,Chien SC,Kuo CC,Wu MD,Cheng MJ,Chen JJ,Chiu HL,Kuo YH

更新日期：2020-08-01 00:00:00

abstract：:Excessive accumulation of iron in the body can lead to organ injury. Some flavonoids which possess high affinity to iron can be used as iron chelators for curing iron overload diseases such as haemochromatosis. In this article, the effects of baicalin and quercetin on different mouse tissues (liver, kidney and heart) ...

journal_title：Natural product research

authors： Zhang Y,Gao Z,Liu J,Xu Z

更新日期：2011-07-01 00:00:00

abstract：:Medicinal plants have been the main remedy to treat various ailments for a long time and nowadays, many drugs have been developed from traditional medicine. This paper reviews some medicinal plants and their main constituents which possess anti-inflammatory activities useful for curing joint inflammation, inflammatory...

journal_title：Natural product research

authors： Maione F,Russo R,Khan H,Mascolo N

更新日期：2016-06-01 00:00:00

abstract：:The hexane and ethanol extracts from Himatanthus bracteatus (Apocynaceae) stems were evaluated for antiviral activity against Zika virus, yellow fever virus and dengue virus 2 and for cytotoxicity in Vero cells by MTT assay. The ethanol extract showed good antiviral activity against the three viruses with selective in...

journal_title：Natural product research

authors： da Silva ML,Stehmann JR,Serafim MSM,Vale VV,Gontijo DC,Brandão GC,Kroon EG,de Oliveira AB

更新日期：2019-11-20 00:00:00

abstract：:The monoterpenoid fractions of three endemic Galium ssp. (Rubiaceae) from Sardinia Island were examined and compared with the iridoidic pattern yet known in Galium species. This comparison evidenced theirs endemic characters. In particular, in G.corsicum and in G. glaucophyllum loganic acid was isolated and identified...

journal_title：Natural product research

authors： Serrilli AM,Ramunno A,Amicucci F,Chicarella V,Santoni S,Ballero M,Serafini M,Bianco A

更新日期：2008-05-10 00:00:00

abstract：:This paper addresses the application of infrared spectroscopy in combination with chemometrics to identify wall painting's binding medium while employing pattern recognition techniques to process FTIR data-set of complex samples. In this regard, based on the historical documents and previous researches, firstly 56 sta...

journal_title：Natural product research

authors： Haghighi Z,Karimy AH,Karami F,Bagheri Garmarudi A,Khanmohammadi M

更新日期：2019-04-01 00:00:00

abstract：:Two new compounds, myrubol (1) and 3-oxo-11α-hydroxyfriedelane (2), were isolated from the roots of Myrica rubra along with eight known compounds (3-10). Their structures were determined through (1)H-NMR and (13)C-NMR spectral data, including 2-D experiments (HMBC, HMQC, (1)H-(1)H COSY and NOESY) and high-resolution m...

journal_title：Natural product research

authors： Li G,Wang D,Xu S

更新日期：2011-01-01 00:00:00

abstract：:Four fractions were prepared from the crude extract of Caesalpinia minax Hance and the inhibitory activity of nitric oxide (NO) production release of RAW 264.7 cells stimulated by lipopolysaccharide (LPS) was evaluated. The ethyl acetate (EtOAc) fraction showed obvious inhibitory effect. Bioassay-guided fractionation ...

journal_title：Natural product research

authors： Liu Q,Bai B,Yang DP,Peng SY,Zhu LP,Luo MH,Zhao ZM

更新日期：2018-04-01 00:00:00

abstract：:A simple and efficient method was developed for simultaneous analysis of five illegal residual β2-agonists in cattle hair. β2-Agonists were quantified by ultra high performance liquid chromatography coupled with electrospray ionisation tandem mass spectrometry operating in positive multiple-reaction monitoring mode. T...

journal_title：Natural product research

authors： Di Stefano V,Pitonzo R,Giaccone V,Alongi A,Macaluso A,Cicero N,Cancemi G,Ferrantelli V

更新日期：2017-02-01 00:00:00

abstract：:Tectona grandis Linn (Teak), is locally known as Sagwan, belongs to Lamiaceae family. It is one of the most valuable timber in the world, due to its beautiful surface and its resistance to termite and fungal damage. The main active ingredient compounds that are responsible for these action are tectoquinone, lapachol a...

journal_title：Natural product research

authors： Vyas P,Yadav DK,Khandelwal P

更新日期：2019-08-01 00:00:00

abstract：:The aim of study was to compare the content of phenolic acids and flavonoids in two cultivars of Lavandula angustifolia: 'Blue River' and 'Ellagance Purple', including flowers and leafy stalks. Total phenolics and total flavonoids contents were determined by UV-Vis spectroscopy. The contents of total phenolics in leaf...

journal_title：Natural product research

authors： Adaszyńska-Skwirzyńska M,Dzięcioł M

更新日期：2017-11-01 00:00:00

abstract：:A new protostane-type triterpenoid bearing an oxetane ring in the side-chain, named alisol W (1), has been obtained from the dried rhizome of Alisma plantago-aquatica subsp. orientale. The structure and absolute configuration of compound 1 was determined from extensive spectroscopic analysis. In addition, the vasorela...

journal_title：Natural product research

authors： Li HM,Liu D,Dai WF,Chen XQ,Li RT

更新日期：2019-11-01 00:00:00

abstract：:The current study introduces a new idea of utilising several bio/chemoinformatics tools in comparing two bio-similar natural molecules viz. curcumin and bisdemethoxycurcumin (BDMC) in order to select a potential nose-to-brain remedy for Alzheimer disease. The comparison comprised several bio/chemo informatics tools. I...

journal_title：Natural product research

authors： Hathout RM,El-Ahmady SH,Metwally AA

更新日期：2018-12-01 00:00:00

abstract：:Two saponins: scrokoelziside A (1), scrokoelziside B (2), one iridoid glycoside, eurostoside (3), and two flavonoids: nepitrin (4) and homoplantaginin (5), were isolated from the leaves of Scrophularia ningpoensis for the first time. Moreover, eight known compounds: cane sugar (6), harpagide (7), aucubin (8), 6-O-meth...

journal_title：Natural product research

authors： Li J,Huang X,Du X,Sun W,Zhang Y

更新日期：2009-01-01 00:00:00

abstract：:The essential oil of Cyclospermum leptophyllum (Pers.) Sprague ex Britton and P. Wilson syn. Apium leptophyllum (Pers.) F. Muell. Ex Benth., family Apiaceae (Umbellifereae), was analysed by GC and GC-MS. The essential oil showed the presence of thymohydroquinone dimethyl ether (50.7%), thymol methyl ether (11.2%), γ-t...

journal_title：Natural product research

authors： Pande C,Tewari G,Singh C,Singh S

更新日期：2011-03-01 00:00:00

abstract：:The comet assay-guided fractionation of the twigs of Manglietia hookeri resulted in the isolation of three sesquiterpene-neolignans, including a new one 5-allyl-2-(4-allyl-phenoxy)-3-[7-(1-hydroxy-1-methyl-ethyl)-1, 4a-dimethyl-decahydro-naphthalen-1-yloxy]-phenol (1), and eudesobovatol A (2) and eudesobovatol B (3), ...

journal_title：Natural product research

authors： Hu X,Sui X,Wang Y,Wang W,Wu H,Zhang F,Tan Y,Zhang F

更新日期：2016-07-01 00:00:00

abstract：:The current study focuses on the chemical composition, and evaluation of antioxidant and antibacterial activity of the aerial parts of Centaurea resupinata subsp. dufourii. Using different chromatographic methods nine compounds 1-9 were isolated. The structural identification of isolated compounds was achieved using s...

journal_title：Natural product research

authors： Bouzghaia B,Moussa MTB,Goudjil R,Harkat H,Pale P

更新日期：2020-01-23 00:00:00

abstract：:Artemisia annua L. is an annual Eurasian desert-steppe plant. The composition of essential oils found in Artemisia annua from Russian (Buryatian) flora was analyzed in this work using gas chromatography mass-spectrometry method. Artemisia ketone, β-selinene, caryophyllene, caryophyllene oxide, germacrene D were the ma...

journal_title：Natural product research

authors： Zhigzhitzhapova SV,Dylenova EP,Gulyaev SM,Randalova TE,Taraskin VV,Tykheev ZA,Radnaeva LD

更新日期：2020-09-01 00:00:00

abstract：:Two new compounds, one sesquiterpene lactone (1) and one phenylethanoid tautomer (2), together with eleven known compounds (3-13) were isolated from the leaves of Ixeridium dentatum. Their structures were determined by extensive spectroscopic methods, including 1D-, 2D-NMR, and mass spectrometry. All compounds were ev...

journal_title：Natural product research

authors： Park S,Nhiem NX,Park JH,Bhattarai KR,Chae HJ,Kim HR,Kim SH

更新日期：2019-04-10 00:00:00

abstract：:A novel alkaloid named oleraciamide C (1), with six known compounds, hydroxydihydrobovolide (2), uracil (3), catechol (4), 4-aminophenol (5), vanillic acid (6) as well as 3-hydroxypyridine (7), were isolated from Portulaca oleracea L. Additionally, hydroxydihydrobovolide (2), 4-aminophenol (5), 3-hydroxypyridine (7) w...

journal_title：Natural product research

authors： Xu L,Ying Z,Wei W,Hao D,Wang H,Zhang W,Li C,Jiang M,Ying X,Liu J

更新日期：2017-04-01 00:00:00

abstract：:Cumin (Cuminum cyminum) is an annual plant from Apiaceae family that is cultivated in Iran as landraces. The most important chemical composition of the cumin essential oil was cuminaldehyde. In this research, the effect of different landraces and growth regulators was evaluated on callus induction, and best callus was...

journal_title：Natural product research

authors： Farvardin A,Ebrahimi A,Hosseinpour B,Khosrowshahli M

更新日期：2017-09-01 00:00:00

abstract：:Plumieride (PLU), an iridoid isolated from Allamanda cathartica flowers, has been studied by our research group due to its anti-inflammatory potential, antidepressant-like and anxiolytic-like effects. This research investigated the involvement of GABAergic and monoaminergic systems in the anxiolytic-like effect elicit...

journal_title：Natural product research

authors： Dalmagro AP,Camargo A,Zimath PL,Bonomini TJ,Zeni ALB,Malheiros A,de Souza MM

更新日期：2020-03-11 00:00:00

abstract：:An aroma chemical emitted from Gerris paludum insularis was analyzed by means of GC and GC-MS. The main constituent was identified as iso amyl alcohol (3-methyl-1-butanol). The chemical showed a characteristic aroma of Gerris paludum insularis. ...

journal_title：Natural product research

authors： Ono T,Miyazawa M

更新日期：2004-06-01 00:00:00