The relation between cutaneous blood flow and cell content in the tuberculin reaction.

abstract：:Epithelial expression of class II antigens encoded by the major histocompatibility complex (MHC) has been proposed as a means by which autoimmune thyroid disease may be initiated and maintained. We studied a rat thyroid epithelial cell line (FRTL-5), which constitutively expresses class I (OX18) but not class II (OX6 ...

journal_title：Scandinavian journal of immunology

authors： Rayner DC,Lydyard PM,de Assis-Paiva HJ,Bidey S,van der Meide P,Varey AM,Cooke A

更新日期：1987-06-01 00:00:00

abstract：:Recent studies performed in Seattle, USA have suggested that pretransplant assignment of high or low donor alloreactivity may predict acute graft-versus-host disease (aGvHD) after allogeneic HLA identical marrow transplantation for acute leukaemia. The effect of such pretransplant assignment was studied in a Scandinav...

journal_title：Scandinavian journal of immunology

authors： Johnsen HE,Bostrom L,Moller J,Jorgensen JA,Jensen L,Ringden O

更新日期：1992-03-01 00:00:00

abstract：:Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disease, which is characterized with overactive immune response. It is well established that the imbalance between Tregs and Th17 cells plays a pivotal role in pathogenesis of UC. In this study, we investigated the impact of functional changes in Treg subs...

journal_title：Scandinavian journal of immunology

authors： Long Y,Zhao X,Xia C,Li X,Fan C,Liu C,Wang C

更新日期：2020-06-01 00:00:00

abstract：:B cells are in analogy with T cells capable of expressing functional IL-2 receptors. IL-2R alpha-chain (CD25) positive T cells have been studied in detail but not much is known about CD25 positive B cells. The aim of this study was to examine the phenotypic properties of the CD25 expressing B cells collected from diff...

journal_title：Scandinavian journal of immunology

authors： Amu S,Gjertsson I,Tarkowski A,Brisslert M

更新日期：2006-11-01 00:00:00

abstract：:CD8+ T cells are thought to play an important role in protective immunity against tuberculosis. We report the identification of three peptides derived from Rv1818c, Rv3812 and Rv3018c proteins of Mycobacterium tuberculosis that bound to HLA-A*0201 molecules and their ability to induce in vitro T-cell response in perip...

journal_title：Scandinavian journal of immunology

authors： Chaitra MG,Shaila MS,Chandra NR,Nayak R

更新日期：2008-04-01 00:00:00

abstract：:Using a recently developed murine model of haematogenously induced Staphylococcus aureus, the authors have characterized the phenotypes and functional properties of inflammatory cells present in the synovium of arthritic mice. The results show that large numbers of granulocytes and macrophages were observed in the inf...

journal_title：Scandinavian journal of immunology

authors： Abdelnour A,Bremell T,Holmdahl R,Tarkowski A

更新日期：1994-04-01 00:00:00

abstract：:KIR2DL2 and KIR2DL3 are important inhibitory receptors that recognize a subset of HLA-C allelic products carrying Ser77 and Asn80. In this study, we have determined KIR2DL2 and KIR2DL3 diversity in the Chinese Han population by a PCR sequence-based typing. Based on sequencing, the coding regions of 166 Chinese Han ind...

journal_title：Scandinavian journal of immunology

authors： He Y,Tao S,Ying Y,He J,Zhu F,Lv H

更新日期：2015-04-01 00:00:00

abstract：:In a previous study we observed that after in vitro treatment with indomethacin, lymphocyte response to phytohaemagglutinin (PHA) in primary biliary cirrhosis (PBC) patients was higher than that of controls. We know that indomethacin also inhibits prostanoid production, and thus in the present work we directly measure...

journal_title：Scandinavian journal of immunology

authors： Chiricolo M,Lenzi M,Bianchi F,Franceschi C,Bartolini G,Orlandi M,Tomasi V,Licastro F

更新日期：1989-09-01 00:00:00

abstract：:The thymus is the major primary immune tissue for the production of functional T lymphocytes in vertebrates. However, its evolutionary origin is unknown. It has recently been shown that the generation of local T cells also occurs in gut-associated lymphoid tissues (GALT). This suggests that the thymus and GALT have si...

journal_title：Scandinavian journal of immunology

authors： Matsunaga T,Rahman A

更新日期：2001-01-01 00:00:00

abstract：:To further investigate the interaction between human mononuclear leucocytes [peripheral blood mononuclear cells (PBMC)] and enterocytes, the effect of a confluent layer of differentiated CACO-2 cells on cytokine kinetics during challenge with bacteria in a compartmentalized coculture model was investigated. Nonpathoge...

journal_title：Scandinavian journal of immunology

authors： Parlesak A,Haller D,Brinz S,Baeuerlein A,Bode C

更新日期：2004-11-01 00:00:00

abstract：:The detection of mRNA in the murine model of tuberculosis for key cytokines involved in protective immunity in the lung tissues revealed a much faster emergence of the interferon (IFN)-gamma response in the intravenous route than in the aerosol route of inoculation. This slower response in the lungs was associated wit...

journal_title：Scandinavian journal of immunology

authors： Cardona PJ,Cooper A,Luquín M,Ariza A,Filipo F,Orme IM,Ausina V

更新日期：1999-04-01 00:00:00

abstract：:In all of four human germinal centre cell-associated B lymphomas carrying sIgM + sIgD F(ab')2 fragments of rabbit antibodies to human mu-chain were accumulated intracellularly, whereas the accumulation of antibodies to delta-chain was considerably less abundant. The accumulation of antibodies to light chain was interm...

journal_title：Scandinavian journal of immunology

authors： Ruud E,Beiske K,Drack A,Steen HB,Godal T

更新日期：1984-05-01 00:00:00

abstract：:The stimulation of peripheral blood mononuclear cells by purified autologous and/or allogeneic monoclonal IgG was studied in five patients with multiple myeloma (MM), nine patients with monoclonal gammopathy of undetermined significance (MGUS) and six healthy individuals. Single cells secreting IFN-gamma or IL-2 were ...

journal_title：Scandinavian journal of immunology

authors： Yi Q,Bergenbrant S,Osterborg A,Osby E,Ostman R,Björkholm M,Holm G,Lefvert AK

更新日期：1993-12-01 00:00:00

abstract：:Inflammatory DCM (iDCM) may be related to autoimmune processes. An immunoadsorption (IA) has been reported to improve cardiac hemodynamics. The benefit of IA is probably related to the removal of autoantibodies. A recent study suggests additional effects of IA on the T cell-mediated immune reactions, especially on reg...

journal_title：Scandinavian journal of immunology

authors： Bulut D,Creutzenberg G,Mügge A

更新日期：2013-01-01 00:00:00

abstract：:The frequency of HLA DQA1, DQB1, and DPB1 mismatches was evaluated in 110 HLA class I- and DRB1-matched, unrelated pairs who were tested in mixed lymphocyte culture (MLC) in connection with a potential allogeneic bone-marrow transplantation between unrelated persons. After typing of the DQA1, DQB1, and DPB1 genes retr...

journal_title：Scandinavian journal of immunology

authors： Partanen J,Koskimies S

更新日期：1994-03-01 00:00:00

abstract：:Haematopoietic precursors first colonizing the avian embryonic thymus are derived from the intraembryonic sites located around the dorsal aortae. These intraembryonic precursors have previously been demonstrated to include cells that harbour T-cell progenitor capacity and express the Ikaros transcription factor, known...

journal_title：Scandinavian journal of immunology

authors： Liippo J,Koskela K,Lassila O

更新日期：2000-11-01 00:00:00

abstract：:Sera from patients with primary biliary cirrhosis recognize various cellular components, such as mitochondria, centromere, nuclear envelope, and multiple nuclear dot antigens. There also appears to be a novel antibody reacting with a particular protein in these sera. The presence of this antibody was investigated by d...

journal_title：Scandinavian journal of immunology

authors： Miyachi K,Matsushima H,Hankins RW,Hirakata M,Mimori T,Hosaka H,Amagasaki Y,Miyakawa H,Kako M,Shibata M,Onozuka Y,Ueno U

更新日期：1998-01-01 00:00:00

abstract：:The occurrence of D-D recombination during the embryonic differentiation of chicken B cells was studied. Ig heavy (H) chains were amplified by polymerase chain reaction from day-12 bursal cDNA, and 30 random V-D-J regions were analysed by DNA sequencing. No gene conversion events were observed in any of the V regions,...

journal_title：Scandinavian journal of immunology

authors： Mansikka A,Toivanen P

更新日期：1991-05-01 00:00:00

abstract：:Neutrophils are essential for the host defence against infection. However, neutrophils may also mediate damage namely during immune mediated pathologies. We therefore tested whether targeting of different cell adhesion molecules with specific monoclonal antibodies might reduce immune mediated neutrophil recruitment bu...

journal_title：Scandinavian journal of immunology

authors： Gonçalves AS,Appelberg R

更新日期：2000-05-01 00:00:00

abstract：:Rabbit Ig against human beta2-microglobulin was found to be mitogenic for human peripheral lymphocytes, tonsil lymphocytes, and appendix and spleen cells. Anti-beta2-m gave increased DNA synthesis, with peak responses on day 3 or 4 and showed a dose-response effect when diluted. The effect was seen in both serum-free ...

journal_title：Scandinavian journal of immunology

authors： Ringeén O,Möller E

更新日期：1975-01-01 00:00:00

abstract：:Inflammatory mediators such as interleukin-1 beta (IL-1 beta), tumour necrosis factor-alpha (TNF-alpha), and interleukin-6 (IL-6) exhibit local autocrine and paracrine effects as well as distant systemic effects on target cells. Human Kupffer cells, the fixed tissue macrophages of the liver, may modulate immune and en...

journal_title：Scandinavian journal of immunology

authors： Kutteh WH,Rainey WE,Carr BR

更新日期：1991-05-01 00:00:00

abstract：:The effect of sera from mice bearing a T cell lymphoid leukaemia (LB) and the supernatants from short term cultures of the tumour cells were studied on cell proliferation using syngeneic and allogeneic normal and tumour cells. An inhibitory activity was demonstrated in 24-48 h supernatants of LB cells in culture and d...

journal_title：Scandinavian journal of immunology

authors： Waldner C,Mongini C,Alvarez E,Roig I,Hajos SE

更新日期：1994-09-01 00:00:00

abstract：:Histamine was shown to suppress the in vitro generation of secondary syngeneic tumour-specific Ly-2+, L3T4- cytotoxic T cells from Ly-2+, L3T4- precursor cells. The sensitivity of the spleen cells from P815X2 mastocytoma-bearing DBA/2 mice to histamine-induced suppression changed during tumour progression; by the time...

journal_title：Scandinavian journal of immunology

authors： Laatikainen A

更新日期：1989-10-01 00:00:00

abstract：:Crude preparations of platelet-activating factors (PAF) derived by methanolic extraction of supernatants from antigen-challenged basophils generally stimulated the secretion of histamine from human peripheral blood leucocytes when co-incubated with these cells in the absence of an additional stimulator. When these cru...

journal_title：Scandinavian journal of immunology

authors： O'Donnell MC,Fiedel BA

更新日期：1981-01-01 00:00:00

abstract：:A Gross virus induced rat T cell lymphoma G1-Tc1 and a Moloney virus induced mouse T cell lymphoma YAC-1 are shown to exert a strong cytotoxic activity against rat yolk sac tumours but not to various types of rat, mouse or human normal cells or tumour cell lines including carcinomas, sarcomas, lymphomas and gliomas. B...

journal_title：Scandinavian journal of immunology

authors： Lindvall M,Eriksson H,Hedlund G,Sjögren HO

更新日期：1997-11-01 00:00:00

abstract：:Mast-cell degranulation is triggered by the bridging of Fc receptor-bound antigen-specific immunoglobulin IgE on the cell surface. In vitro experiments suggest that antibody affinity and nonspecific IgE may affect the mast-cell function, however, their importance in vivo is unclear. Investigations of the effects of th...

journal_title：Scandinavian journal of immunology

authors： Mitchell AJ,Moss ND,Collins AM

更新日期：2002-01-01 00:00:00

abstract：:The role of elevated intracellular calcium concentration [Ca2+]i in the LPS-induced activation of interleukin-1 beta (IL-1 beta) production was examined in cells representing different stages of myeloid differentiation (undifferentiated monocytic leukaemia cell line THP-1, THP-1 cells induced to adherent, macrophage-l...

journal_title：Scandinavian journal of immunology

authors： Hurme M,Viherluoto J,Nordström T

更新日期：1992-09-01 00:00:00

abstract：:The object of this work was to measure the levels of monocyte-derived dendritic cell precursors (pDC1) and plasmacytoid dendritic cell precursors (pDC2) in peripheral blood mononuclear cells (PBMC) of patients with thymomatous MG and to assess the ratio of pDC1/pDC2 in these patients. Three-colour monoclonal antibody ...

journal_title：Scandinavian journal of immunology

authors： Zhang LY,Wang W,Feng YK,Liu YH,Wang QS

更新日期：2010-06-01 00:00:00

abstract：:Allergic airway disorders such as asthma and allergic rhinitis are mainly caused by inhaled allergen-induced improper activation and responses of immune and non-immune cells. One important response is the production of IL-27 by macrophages and dendritic cells (DCs) during the early stage of airway allergies. IL-27 exe...

journal_title：Scandinavian journal of immunology

authors： Jafarzadeh A,Nemati M,Jafarzadeh S,Chauhan P,Saha B

更新日期：2021-02-01 00:00:00

abstract：:Human CD26 has dipeptidyl peptidase-4 (DPP IV) enzyme activity and binds to adenosine deaminase (ADA). CD26 is costimulatory for lymphocytes and has a circulating soluble form (sCD26). DPP IV enzyme inhibition is a new successful type 2 diabetes therapy. We examined whether the ADA binding and catalytic functions of s...

journal_title：Scandinavian journal of immunology

authors： Yu DM,Slaitini L,Gysbers V,Riekhoff AG,Kähne T,Knott HM,De Meester I,Abbott CA,McCaughan GW,Gorrell MD

更新日期：2011-02-01 00:00:00