Gut roundtable meeting paper: selected recent advances in hepatocellular carcinoma.

abstract：BACKGROUND AND AIMS:Many neuroendocrine gastrointestinal tumours express receptors for the regulatory peptide somatostatin. Among the five existing somatostatin receptor (sst) subtypes, sst2A is the most frequently expressed in these tumours. However, little information is available about the cellular location of sst2A...

journal_title：Gut

authors： Gugger M,Waser B,Kappeler A,Schonbrunn A,Reubi JC

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Ethanol undergoes a first pass metabolism (FPM) in the stomach and liver. Gastric FPM of ethanol primarily depends on the activity of gastric alcohol dehydrogenase (ADH). In addition, the speed of gastric emptying (GE) may modulate both gastric and hepatic FPM of ethanol. AIMS:To study the effect of modulat...

journal_title：Gut

authors： Oneta CM,Simanowski UA,Martinez M,Allali-Hassani A,Parés X,Homann N,Conradt C,Waldherr R,Fiehn W,Coutelle C,Seitz HK

更新日期：1998-11-01 00:00:00

abstract：:Jejunal biopsies from 15 Greenlandic and three Danish patients with adult type hypolactasia and nine Greenlandic and 15 Danish patients with normal lactase activity were analysed quantitatively for lactase protein by crossed immunoelectrophoresis. A constant correlation between the amount of lactase activity and immun...

journal_title：Gut

authors： Skovbjerg H,Gudmand-Høyer E,Fenger HJ

更新日期：1980-05-01 00:00:00

abstract：:To examine socioeconomic factors, dietary and other personal habits, and medical history as risk factors for ulcerative colitis, we studied 167 (98%) of all prevalent cases of ulcerative colitis diagnosed in Uppsala county from 1945 to 1964 and 167 age and sex matched population controls. Ulcerative colitis patients w...

journal_title：Gut

authors： Samuelsson SM,Ekbom A,Zack M,Helmick CG,Adami HO

更新日期：1991-12-01 00:00:00

abstract：:Nutritional status and immune function were correlated with clinical features in 56 patients with Crohn's disease. These were divided arbitrarily into either undernourished or well nourished groups according to whether their midarm circumference was below or above 90% of ideal standard. Results were also compared with...

journal_title：Gut

authors： Harries AD,Danis VA,Heatley RV

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND:In this study, we identify the nature of the immunological response of human peripheral blood mononuclear cells (PBMC) and lamina propria gastric lymphocytes (LPL) to two Helicobacter pylori antigens, the neutrophil activating protein (NapA) and alkyl hydroperoxide reductase (AphC). These antigens were ident...

journal_title：Gut

authors： Windle HJ,Ang YS,Athie-Morales V,McManus R,Kelleher D

更新日期：2005-01-01 00:00:00

abstract：:Dysmotility of the duodenum and proximal jejunum has been reported in patients with irritable bowel syndrome. This study extended these findings by recording fasting ambulatory motility from electronic strain gauge sensors sited in the jejunum and ileum of eight diarrhoea predominant irritable bowel syndrome patients ...

journal_title：Gut

authors： Gorard DA,Libby GW,Farthing MJ

更新日期：1994-02-01 00:00:00

abstract：:Rats were subjects to right hemicolectomy (including removal of the caecum), left hemicolectomy or subtotal colectomy. Body weight resumed and maintained a rate of increase very similar to that in control rats. After hemicolectomy, food intake showed no change. Faecal weight increased by about one-third after right he...

journal_title：Gut

authors： Masesa PC,Forrester JM

更新日期：1977-01-01 00:00:00

abstract：OBJECTIVE:Diverticulitis is a common disease with a substantial clinical and economic burden. Besides dietary fibre, the role of other foods in the prevention of diverticulitis is underexplored. DESIGN:We prospectively examined the association between consumption of meat (total red meat, red unprocessed meat, red proc...

journal_title：Gut

authors： Cao Y,Strate LL,Keeley BR,Tam I,Wu K,Giovannucci EL,Chan AT

更新日期：2018-03-01 00:00:00

abstract：:Removal of the right lobe of the liver which was occupied largely by metastases, together with resection of ileal primary tumours, brought about complete remission of symptoms and signs in a 43-year-old man with a six-year history of the carcinoid syndrome. Investigations should be orientated toward surgery. When prac...

journal_title：Gut

authors： Zeegen R,Rothwell-Jackson R,Sandler M

更新日期：1969-08-01 00:00:00

abstract：:The metabolism of pure radioiodine labelled Clq has been observed in five patients with ulcerative colitis, five patients with Crohn's disease, and in five control subjects. Both the fractional catabolic rate and the synthesis rate of Clq were increased in the five patients with Crohn's disease and in four of the five...

journal_title：Gut

authors： Potter BJ,Hodgson HJ,Mee AS,Jewell DP

更新日期：1979-11-01 00:00:00

abstract：:Hepatitis B and hepatitis C infections are important causes of end-stage liver disease and primary liver cancer. Successful antiviral treatment prior to the development of cirrhosis will prevent most of the morbidity and mortality associated with those infections. This can be achieved for a high proportion of patients...

journal_title：Gut

authors： Mutimer DJ,Lok A

更新日期：2012-05-01 00:00:00

abstract：:Nineteen healthy subjects were studied and 17 patients with gastric ulcer before and after ulcer healing with carbenoxolone. Gastric deoxytibonucleic acid (DNA) loss was measured as an index of epithelial cell turnover, and N-acetylneuraminic acid (NANA) content of gastric juice as an index of mucus secretion. In norm...

journal_title：Gut

authors： Domschke W,Domschke S,Hagel J,Demling L,Croft DN

更新日期：1977-10-01 00:00:00

abstract：BACKGROUND AND AIM:There is controversy regarding whether paramyxovirus infection is causally associated with inflammatory bowel disease (IBD). The latest cohort study claimed that atypical measles and mumps infections in childhood may be risk factors for later IBD. This study was conducted to clarify the validity of a...

journal_title：Gut

authors： Iizuka M,Saito H,Yukawa M,Itou H,Shirasaka T,Chiba M,Fukushima T,Watanabe S

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:Postpolypectomy surveillance guidelines for colorectal cancer introduced the concept of 'risk stratification'; however, few studies have been conducted for validation of its usefulness. The aim of this study was to assess the 5-year incidence of advanced neoplasia recurrence based on the risk stratification s...

journal_title：Gut

authors： Chung SJ,Kim YS,Yang SY,Song JH,Kim D,Park MJ,Kim SG,Song IS,Kim JS

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Many lines of evidence suggest that T helper cell type 1 (Th1) immune responses predominate in Crohn's disease (CD). Recently, a novel transcription factor T-box expressed in T cells (T-bet) has been reported as the master regulator of Th1 development. This study was designed to investigate the role...

journal_title：Gut

authors： Matsuoka K,Inoue N,Sato T,Okamoto S,Hisamatsu T,Kishi Y,Sakuraba A,Hitotsumatsu O,Ogata H,Koganei K,Fukushima T,Kanai T,Watanabe M,Ishii H,Hibi T

更新日期：2004-09-01 00:00:00

abstract：:Continued bleeding or early rebleeding is associated with a poor prognosis in patients with variceal haemorrhage. It is not clear why bleeding stops in some patients and continues or restarts in others. It is suggested that secondary haemodynamic changes in the splanchnic circulation after a bleed may contribute to th...

journal_title：Gut

authors： McCormick PA,Jenkins SA,McIntyre N,Burroughs AK

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Wilson's disease is a rare inborn disease related to copper storage, leading to liver cirrhosis and neuropsychological deterioration. Clinical data on larger cohorts are limited owing to low disease frequency. OBJECTIVE AND METHODS:We performed a retrospective analysis of 163 patients with Wilson's disease,...

journal_title：Gut

authors： Merle U,Schaefer M,Ferenci P,Stremmel W

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:A previous pilot study showed that early arrival time of a microbubble in a hepatic vein is a sensitive indicator of cirrhosis. AIM:To see if this index can also grade diffuse liver disease. PATIENTS:Thirty nine fasted patients with histologically characterised disease were studied prospectively. Nine pati...

journal_title：Gut

authors： Blomley MJ,Lim AK,Harvey CJ,Patel N,Eckersley RJ,Basilico R,Heckemann R,Urbank A,Cosgrove DO,Taylor-Robinson SD

更新日期：2003-08-01 00:00:00

abstract：:This paper describes the construction and use of "radio pills" which transmit changes in intraluminar pressure. ...

journal_title：Gut

authors： CONNELL AM,ROWLANDS EN

更新日期：1960-09-01 00:00:00

abstract：:The effects on gastric emptying of a solid meal of the specific 5-HT3-receptor antagonist ICS 205-930, 10 mg and 20 mg intravenously were assessed with a scintigraphic technique in 12 normals. The 50% emptying time was less, the lag phase was shorter and the post lag emptying rate was faster after 20 mg ICS 205-930 (p...

journal_title：Gut

authors： Akkermans LM,Vos A,Hoekstra A,Roelofs JM,Horowitz M

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Large numbers of plasma cells (PC) localise in the intestinal lamina propria (LP) where they play a critical role in the defence against pathogens. This study analyses the level of maturation reached by normal human colon LPPC in comparison with that of bone marrow (BM) PC. METHODS:A technique was ...

journal_title：Gut

authors： Medina F,Segundo C,Campos-Caro A,Salcedo I,García-Poley A,Brieva JA

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Low grade dysplasia (LGD) is believed to predispose to colorectal cancer (CRC), and proctocolectomy has been advocated when this is identified. Between 1978 and 1990, 160 patients with longstanding extensive ulcerative colitis (UC) were recruited for annual colonoscopic surveillance and 40 developed...

journal_title：Gut

authors： Lim CH,Dixon MF,Vail A,Forman D,Lynch DA,Axon AT

更新日期：2003-08-01 00:00:00

abstract：:A manometric method was developed to study the motor activity in the unprepared human colon, and the results in eight healthy subjects were compared with those obtained in the same subjects after bowel cleansing with a non-absorbable solution containing polyethylene glycol 4000 (PEG). A tube assembly (4.5 m long, 12 l...

journal_title：Gut

authors： Lémann M,Flourié B,Picon L,Coffin B,Jian R,Rambaud JC

更新日期：1995-11-01 00:00:00

abstract：:This case report describes the histological and macroscopic changes seen within a few months in the gastric mucosa of a 28 year old woman patient with upper abdominal symptoms. With hindsight these changes were the first signs of Sjögren's syndrome. ...

journal_title：Gut

authors： van Leeuwen ML,Tjiong HL,van Blankenstein M,Mulder AH,Bakker CM

更新日期：1993-08-01 00:00:00

abstract：:Completeness of vagotomy has been assessed by use of the electrical stimulation test and the insulin test in 50 patients suffering from chronic duodenal ulceration. A positive result from either was taken as evidence of incomplete vagotomy. The electrical stimulation test provided such evidence more often than the ins...

journal_title：Gut

authors： Hollanders D

更新日期：1971-08-01 00:00:00

abstract：BACKGROUND/AIMS:By contrast with animal models, in most cases it is not possible to examine the systemic response in patients in the first hours after onset of acute pancreatitis. The aim was to determine whether endoscopic retrograde cholangiopancreaticography (ERP)-induced pancreatitis can be used as a human model fo...

journal_title：Gut

authors： Messmann H,Vogt W,Holstege A,Lock G,Heinisch A,von Fürstenberg A,Leser HG,Zirngibl H,Schölmerich J

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Sulfhydryl (SH) compounds are essential in maintaining mucosal integrity in the gastrointestinal tract. A decrease in colonic mucosal SH compounds affects the redox status of the mucosa, resulting in vulnerability to further attacks. Therefore, there is a strong need for in vivo evaluation of SH compounds in...

journal_title：Gut

authors： Togashi H,Oikawa K,Adachi T,Sugahara K,Ito J,Takeda T,Watanabe H,Saito K,Saito T,Fukui T,Takeda H,Ohya H,Kawata S

更新日期：2003-09-01 00:00:00

abstract：:To investigate factors which predispose to relapse in patients with ulcerative colitis, we conducted a survey to compare the events occurring in the four weeks preceding the clinic attendance of 62 outpatients in remission with those taking place in the same period before the onset of relapse in 21 patients attending ...

journal_title：Gut

authors： Rampton DS,McNeil NI,Sarner M

更新日期：1983-03-01 00:00:00

abstract：:Our life expectancy is increasing, leading to a rise in the ageing population. Ageing is associated with a decline in physiological function and adaptive capacity. Altered GI physiology can affect the amount and types of nutrients digested and absorbed as well as impact the intestinal microbiota. The intestinal microb...

journal_title：Gut

authors： An R,Wilms E,Masclee AAM,Smidt H,Zoetendal EG,Jonkers D

更新日期：2018-12-01 00:00:00