Abstract:
:This paper describes the construction and use of "radio pills" which transmit changes in intraluminar pressure.
journal_name
Gutjournal_title
Gutauthors
CONNELL AM,ROWLANDS ENdoi
10.1136/gut.1.3.266keywords:
subject
Has Abstractpub_date
1960-09-01 00:00:00pages
266-72eissn
0017-5749issn
1468-3288journal_volume
1pub_type
杂志文章相关文献
GUT文献大全abstract:BACKGROUND AND AIMS:Emerging evidence suggests that highly treatment-resistant tumour-initiating cells (TICs) play a central role in the pathogenesis of pancreatic cancer. Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) is considered to be a novel anticancer agent; however, recent studies have shown th...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.2008.149039
更新日期:2009-07-01 00:00:00
abstract::Symptom assessment, by structured interview or questionnaire, is central to the diagnosis of gastro-oesophageal reflux disease (GORD). However, empiric support for the diagnostic utility of reflux symptom measures is lacking. Reliable reflux symptom questionnaires have been developed with content validity. These quest...
journal_title:Gut
pub_type: 杂志文章,评审
doi:10.1136/gut.2003.034280
更新日期:2004-05-01 00:00:00
abstract:OBJECTIVE:Hippo signalling is a recently identified major oncosuppressive pathway that plays critical roles in inhibiting hepatocyte proliferation, survival and hepatocellular carcinoma (HCC) formation. Hippo kinase (Mst1 and Mst2) inhibits HCC proliferation by suppressing Yap/Taz transcription activities. As human HCC...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gutjnl-2017-314061
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVE:Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA was detected in faeces of patients with COVID-19, the activity and infectivity of the virus in the GI tract during disease course is largely unknown. We investigated temporal transcriptional activity of SARS-CoV-2 and its association wi...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gutjnl-2020-322294
更新日期:2021-02-01 00:00:00
abstract:BACKGROUND AND AIMS:Both bile salts and glutathione participate in the generation of canalicular bile flow. In this work, we have investigated the effect of different bile salts on hepatic glutathione metabolism. METHODS:Using the isolated and perfused rat liver, we studied hepatic glutathione content, and metabolism ...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.50.5.701
更新日期:2002-05-01 00:00:00
abstract::Gastroparesis is defined by the presence of delayed gastric emptying (GE) in the absence of mechanical obstruction. Symptoms that have been attributed to gastroparesis include postprandial fullness, early satiation nausea and vomiting. Gastroprokinetic drugs are the preferred treatment option. A number of problems wit...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gutjnl-2013-306084
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND AND AIMS:Low grade dysplasia (LGD) is believed to predispose to colorectal cancer (CRC), and proctocolectomy has been advocated when this is identified. Between 1978 and 1990, 160 patients with longstanding extensive ulcerative colitis (UC) were recruited for annual colonoscopic surveillance and 40 developed...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.52.8.1127
更新日期:2003-08-01 00:00:00
abstract::Dysmotility of the duodenum and proximal jejunum has been reported in patients with irritable bowel syndrome. This study extended these findings by recording fasting ambulatory motility from electronic strain gauge sensors sited in the jejunum and ileum of eight diarrhoea predominant irritable bowel syndrome patients ...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.35.2.203
更新日期:1994-02-01 00:00:00
abstract::In 19 subjects (four controls, one gastric ulcer and 14 duodenal ulcer) maximal gastric secretion was evoked with histamine 0.13 mumol/kg/h (0.04 mg/kg/h) for two to two and a half hours. A slow intravenous bolus dose of 200 mg cimetidine was given at the beginning of the last hour. Gastric secretion was measured befo...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.26.8.766
更新日期:1985-08-01 00:00:00
abstract:OBJECTIVES:Novel imaging methods based on specific molecular targets to detect both established neoplasms and their precursor lesions are highly desirable in cancer medicine. Previously, we identified claudin-4, an integral constituent of tight junctions, as highly expressed in various gastrointestinal tumours includin...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gutjnl-2012-302577
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND/AIMS:To evaluate the response of endocrine cells of the gastric oxyntic mucosa in hypergastrinaemic patients to either antrectomy or treatment with the somatostatin analogue octreotide. PATIENTS:(a) Two patients with enterochromaffin-like (ECL) cell carcinoid and chronic atrophic gastritis, treated with ant...
journal_title:Gut
pub_type: 临床试验,杂志文章
doi:10.1136/gut.38.5.668
更新日期:1996-05-01 00:00:00
abstract::We investigated the effects of medium (MCT) and long (LCT) chain triglyceride test meals on gall bladder contraction (using ultrasonography) and small intestinal bile acid concentrations and ileal flow rates (using intubation techniques) in normal individuals. Comparing the effects of ingesting medium chain triglyceri...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.25.4.405
更新日期:1984-04-01 00:00:00
abstract::An investigation of immunological parameters was conducted in 38 patients with Crohn's disease. The immunological tests employed included skin tests with dinitrochlorobenzene and a battery of common skin test antigens, lymphocyte transformation with phytohaemagglutinin and pokeweed mitogen, serum immunoglobulins, and ...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.17.2.100
更新日期:1976-02-01 00:00:00
abstract::To investigate the basis of subclinical alveolitis in patients with primary biliary cirrhosis, 10 primary biliary cirrhosis patients were studied by bronchoalveolar lavage. Both bronchoalveolar lavage lymphoid and non-lymphoid cell populations were analysed using immunocytological methods to determine their proportion...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.31.2.208
更新日期:1990-02-01 00:00:00
abstract:BACKGROUND AND AIMS:Colonoscopic surveillance for cancer in longstanding extensive ulcerative colitis relies heavily on non-targeted mucosal biopsies. Chromoendoscopy can aid detection of subtle mucosal abnormalities. We hypothesised that routine pancolonic indigo carmine dye spraying would improve the macroscopic dete...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.2003.016386
更新日期:2004-02-01 00:00:00
abstract::Iron deficiency anaemia is one of the most common disorders in the world. Also, one third of inflammatory bowel disease (IBD) patients suffer from recurrent anaemia. Anaemia has significant impact on the quality of life of affected patients. Chronic fatigue, a frequent IBD symptom itself, is commonly caused by anaemia...
journal_title:Gut
pub_type: 杂志文章,评审
doi:10.1136/gut.2003.035758
更新日期:2004-08-01 00:00:00
abstract:BACKGROUND AND AIMS:The diagnostic yield of capsule endoscopy (CE) compared with magnetic resonance imaging (MRI) in small bowel Crohn's disease is not well established. We prospectively investigated CE, MRI, and double contrast fluoroscopy in patients with suspected small bowel Crohn's disease. METHODS:Fifty two cons...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.2005.069427
更新日期:2005-12-01 00:00:00
abstract::Using 24 hour pH monitoring as a reference standard, the usefulness of the acid perfusion (AP) test in predicting gastro-oesophageal reflux disease (GORD) was assessed in 71 non-cardiac chest pain (NCCP) patients and 23 endoscopic oesophagitis patients. Of the 71 NCCP patients, 35 had a positive AP test (of whom 20 ha...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.30.3.305
更新日期:1989-03-01 00:00:00
abstract::Nutritional status and immune function were correlated with clinical features in 56 patients with Crohn's disease. These were divided arbitrarily into either undernourished or well nourished groups according to whether their midarm circumference was below or above 90% of ideal standard. Results were also compared with...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.25.5.465
更新日期:1984-05-01 00:00:00
abstract::The eosinophil population is increased in the jejunal mucosa of patients with coeliac disease. Eosinophils may participate in the mucosal damage by releasing their granule components that have cytotoxic properties such as eosinophil cationic protein (ECP) and major basic protein (MBP). This study aimed to assess the p...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.33.9.1190
更新日期:1992-09-01 00:00:00
abstract::We investigated the distribution of short chain fatty acids (SCFA) in enema samples taken from subjects before sigmoidoscopy as an indicator of possible microbial community differences between subjects subsequently diagnosed as normal or having colonic disorders. The major SCFA in all groups were acetic, propionic, an...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.29.11.1539
更新日期:1988-11-01 00:00:00
abstract::A method is described for measuring transit time through the gut which requires the collection of only one stool. A dose of 20 radio-opaque markers is given to the subject on each of three consecutive days with breakfast, each dose of marker being of a different type. The first stool passed after rising on the fourth ...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.17.3.219
更新日期:1976-03-01 00:00:00
abstract:BACKGROUND:Small intestinal epithelial cells (IEC) show apoptosis in physiological turnover of cells and in certain inflammatory diseases. AIMS:To investigate the role of caspases in the progression of IEC apoptosis in vivo. METHODS:IEC were separated along the villus-crypt axis from the jejunum of normal and Nippost...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.50.1.71
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVE:Pancreatic ductal adenocarcinoma (PDAC) is the deadliest cancer. Cancer-associated thrombosis/thromboembolism (CAT), frequently observed in PDAC, is known as a poor prognostic factor. Here, we investigated the underlying mechanisms between PDAC and CAT, and performed a trial of therapeutic approach for PDAC u...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gutjnl-2020-320608
更新日期:2020-10-21 00:00:00
abstract::Studies have been made of mucus glycoprotein biosynthesis in different regions of the lower gastrointestinal tract in normal patients and those with ulcerative colitis (UC), active or inactive, by means of 3H-glucosamine (3H-GlcNH2)--35S-sulphate double labelling of epithelial biopsy specimens under culture conditions...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.34.7.926
更新日期:1993-07-01 00:00:00
abstract::Extracorporeal shock wave lithotripsy of pancreatic duct stones (largest stone 12 (SD) 6 mm) was performed in 24 patients with abdominal pain and a dilated duct system (main pancreatic duct 10 (3) mm). The procedure was well tolerated in all but two patients, who had a mild pancreatitic attack immediately after lithot...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.33.7.969
更新日期:1992-07-01 00:00:00
abstract:OBJECTIVE:We aimed at the identification of genetic alterations that may functionally substitute for CTNNB1 mutation in ß-catenin-activated hepatocellular adenomas (HCAs) and hepatocellular carcinoma (HCC). DESIGN:Large cohorts of HCA (n=185) and HCC (n=468) were classified using immunohistochemistry. The mutational s...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gutjnl-2018-317632
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Lamina propria (LPLs) and intraepithelial (IELs) lymphocytes are markedly increased in coeliac mucosa, and are thought to play a crucial role in the generation of villous atrophy in coeliac disease (CD). However, the mechanisms by which they mediate the killing of enterocytes in this condition are still poor...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.49.3.380
更新日期:2001-09-01 00:00:00
abstract:BACKGROUND:Hereditary forms of chronic idiopathic intestinal pseudo-obstruction (CIIP) are well described but the aetiology of most cases of sporadic CIIP is unknown. AIM:To determines whether herpes viruses can persist in the gastrointestinal tract, thereby implicating them in the pathogenesis of CIIP. METHODS:Twent...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.41.1.100
更新日期:1997-07-01 00:00:00
abstract:BACKGROUND:Previous experimental studies have suggested many possible anti-cancer mechanisms for green tea, but epidemiological evidence for the effect of green tea consumption on gastric cancer risk is conflicting. OBJECTIVE:To examine the association between green tea consumption and gastric cancer. METHODS:We anal...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.2008.166710
更新日期:2009-10-01 00:00:00