Abstract:
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journal_name
Sci Repjournal_title
Scientific reportsauthors
Malabirade A,Morgado-Brajones J,Trépout S,Wien F,Marquez I,Seguin J,Marco S,Velez M,Arluison Vdoi
10.1038/s41598-017-15019-ysubject
Has Abstractpub_date
2017-11-10 00:00:00pages
15651issue
1issn
2045-2322pii
10.1038/s41598-017-15019-yjournal_volume
7pub_type
已发布勘误abstract::Nitric oxide (NO), a vascular signaling molecule, is primarily produced by endothelial NO synthase. Recently, a functional endothelial NO synthase (eNOS) was described in red blood cells (RBC). The RBC-eNOS contributes to the intravascular NO pool and regulates physiological functions. However the regulatory mechanism...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep26935
更新日期:2016-06-27 00:00:00
abstract::Calcitriol, a metabolite of vitamin D, is often used in osteoporosis clinics. However, the material has other bioactivities; for example, it accelerates angiogenesis, has anti-inflammatory properties, and inhibits oxidative stress. We investigated the effects of calcitriol in a random skin flap rat model. "McFarlane f...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep18945
更新日期:2016-01-06 00:00:00
abstract::The optical gain and spontaneous emission characteristics of low In-content AlInN-delta-GaN quantum wells (QWs) are analyzed for deep ultraviolet (UV) light emitting diodes (LEDs) and lasers. Our analysis shows a large increase in the dominant transverse electric (TE) polarized spontaneous emission rate and optical ga...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep22983
更新日期:2016-03-10 00:00:00
abstract::The adsorption of glycine, glutamic acid, histidine and phenylalanine on single-layer graphdiyne/graphene is investigated by ab initio calculations. The results show that for each amino acid molecule, the adsorption energy on graphdiyne is larger than the adsorption energy on graphene and dispersion interactions predo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep16720
更新日期:2015-11-16 00:00:00
abstract::Targeting embryonic stem cells (ESCs) is important for ESC labeling, drug delivery and cell fate control. In this study, we identified twenty-two phage clones that bind specifically to the hESC cell line X-01, which was derived from human blastocysts of Chinese origin. One phage (H178), which displays the sequence VGG...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep03134
更新日期:2013-11-05 00:00:00
abstract::The Notch signaling network determines stemness in various tissues and targeting signaling activity in malignant brain cancers by gamma-secretase inhibitors (GSI) has shown promising preclinical success. However, the clinical translation remains challenging due to severe toxicity side effects and emergence of therapy ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-72480-y
更新日期:2020-10-01 00:00:00
abstract::Tuneable pressure effects associated with changing interlayer distances in two-dimensional graphene oxide (GO)/reduced GO (rGO) layers are demonstrated through monitoring the changes in the spin-crossover (SCO) temperature (T 1/2) of [Fe(Htrz)2(trz)](BF4) nanoparticles (NPs) incorporated in the interlayer spaces of th...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-12444-x
更新日期:2017-09-22 00:00:00
abstract::For N indistinguishable bosons or fermions impinged on a M-port Haar-random unitary network the average probability to count n 1, … n r particles in a small number r ≪ N of binned-together output ports takes a Gaussian form as N ≫ 1. The discovered Gaussian asymptotic law is the well-known asymptotic law for distingui...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-00044-8
更新日期:2017-02-16 00:00:00
abstract::In external radiotherapy (RT), the use of flattening filter-free (FFF) radiation beams obtained by removing the flattening filter (FF) in standard linear accelerators is rapidly increasing, and the benefits of clinical use are the issue of research. Advanced treatment techniques have increased the interest in the oper...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-66079-6
更新日期:2020-06-02 00:00:00
abstract::Transplantation of cardiomyocytes derived from induced pluripotent stem cell (iPSC-CMs) is a promising approach for increasing functional CMs during end-stage heart failure. Although major histocompatibility complex (MHC) class I matching between donor cells and recipient could reduce acquired immune rejection, innate...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-47134-3
更新日期:2019-07-25 00:00:00
abstract::Resistance to 157 different herbicides and 88% of known sites of action has been observed, with many weeds resistant to two or more modes. Coupled with tighter environmental regulation, this demonstrates the need to identify new modes of action and novel herbicides. The plant sphingolipid biosynthetic enzyme, inositol...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-44544-1
更新日期:2019-05-30 00:00:00
abstract::Gene targeting in embryonic stem cells (ESCs) has become the principal technology for generating knockout models. Although numerous studies have predicted that the disruption of p53 leads to increased developmental anomalies and malignancies, most p53 knockout mice develop normally. Therefore, the role of p53 in anima...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep00945
更新日期:2012-01-01 00:00:00
abstract::Test anxiety is a condition in which people experience extreme distress and anxiety before and in test situations. It affects up to 40 percent of all students. Conventional treatment includes both medication and psychotherapy, but studies also demonstrated that placebos affect anxiety symptoms. Although in the traditi...
journal_title:Scientific reports
pub_type: 杂志文章,随机对照试验
doi:10.1038/s41598-019-49466-6
更新日期:2019-09-16 00:00:00
abstract::We analyze the quantum phase effects for point-like charges and electric (magnetic) dipoles under a natural assumption that the observed phase for a dipole represents the sum of corresponding phases for charges composing this dipole. This way we disclose two novel quantum phases for charged particles, which we named a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-30423-8
更新日期:2018-08-09 00:00:00
abstract::State-of-the-art of preoperative planning for forearm orthopaedic surgeries is currently limited to simple bone procedures. The increasing interest of clinicians for more comprehensive analysis of complex pathologies often requires dynamic models, able to include the soft tissue influence into the preoperative process...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-63436-3
更新日期:2020-04-14 00:00:00
abstract::We introduce a non-invasive approach for optogenetic regulation in biological cells through highly scattering skull tissue using wavefront shaping. The wavefront of the incident light was systematically controlled using a spatial light modulator in order to overcome multiple light-scattering in a mouse skull layer and...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep13289
更新日期:2015-08-21 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-61223-8
更新日期:2020-03-03 00:00:00
abstract::Chronic consumption of excess ethanol increases the risk of colorectal cancer. The pathogenesis of ethanol-related colorectal cancer (ER-CRC) is thought to be partly mediated by gut microbes. Specifically, bacteria in the colon and rectum convert ethanol to acetaldehyde (AcH), which is carcinogenic. However, the effec...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep27923
更新日期:2016-06-13 00:00:00
abstract::Editing in microRNAs, particularly in seed can significantly alter the choice of their target genes. We show that out of 13 different human tissues, different regions of brain showed higher adenosine to inosine (A-to-I) editing in mature miRNAs. These events were enriched in seed sequence (73.33%), which was not obser...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-02397-6
更新日期:2017-05-26 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-66769-1
更新日期:2020-06-16 00:00:00
abstract::Bioerosion is a process with a high socio-economic impact that contributes to coastal retreat, and likely to increase with climate change. Whereas limestone bioerosion is well explained by a combination of mechanical and chemical pathways, the bioerosion mechanisms of silicates, which are harder and chemically more re...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-70265-x
更新日期:2020-08-07 00:00:00
abstract::Bisphenol A (BPA) is one of the commonest Endocrine Disruptor Compounds worldwide. It interferes with vertebrate reproduction, possibly by inducing deregulation of epigenetic mechanisms. To determine its effects on female reproductive physiology and investigate whether changes in the expression levels of genes related...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep21982
更新日期:2016-02-25 00:00:00
abstract::This work demonstrates the dynamic through-silicon-via (TSV) filling process through staged electrodeposition experiments at different current densities. Different morphologies corresponding to TSV filling results can be obtained by controlling the applied current density. Specifically, a low current density (4 mA/cm2...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep46639
更新日期:2017-04-19 00:00:00
abstract::Sclerotinia sclerotiorum, the causal agent of white stem rot, is responsible for significant losses in crop yields around the globe. While our understanding of S. sclerotiorum infection is becoming clearer, genetic control of the pathogen has been elusive and effective control of pathogen colonization using traditiona...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-25434-4
更新日期:2018-05-09 00:00:00
abstract::Anthropometric indices determine important risk factors for many chronic diseases. However, to date, no study has simultaneously analyzed the capabilities of trunk circumference and width indices to identify hypertension and type 2 diabetes in a large-scale screening study. The objectives of this study were to examine...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-31624-x
更新日期:2018-09-05 00:00:00
abstract::Iron overload is associated with various pathological changes which contribute to heart failure. Here, we examined mechanisms via which iron alters cardiomyocyte insulin sensitivity. Treatment of primary adult and neonatal cardiomyocytes as well as H9c2 cells with iron decreased insulin sensitivity determined via West...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-41111-6
更新日期:2019-03-15 00:00:00
abstract::Prenatal skeletal muscle development genetically determines postnatal muscle characteristics such as growth and meat quality in pigs. However, the molecular mechanisms underlying prenatal skeletal muscle development remain unclear. Here, we performed the first genome-wide analysis of chimeric RNAs, single nuclear poly...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29039
更新日期:2016-06-29 00:00:00
abstract::Entamoeba possesses a highly divergent mitochondrion-related organelle known as the mitosome. Here, we report the discovery of a novel protein in Entamoeba, which we name Mitosomal β-barrel Outer Membrane Protein of 30 kDa (MBOMP30). Initially identified through in silico analysis, we experimentally confirmed that MBO...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep08545
更新日期:2015-02-25 00:00:00
abstract::Antiretroviral therapy containing an integrase strand transfer inhibitor (INSTI) plus two NRTIs has become the recommended treatment for antiretroviral-naive HIV-1-infected patients in the updated guidelines. We aimed to determine the prevalence of INSTI-related mutations in Taiwan. Genotypic resistance assays were pe...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep35779
更新日期:2016-10-25 00:00:00
abstract::When making choices between smaller, sooner rewards and larger, later ones, people tend to discount future outcomes. Individual differences in temporal discounting in older adults have been associated with episodic memory abilities and entorhinal cortical thickness. The cause of this association between better memory ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-63373-1
更新日期:2020-04-14 00:00:00