Metasurface electrode light emitting diodes with planar light control.

abstract：:Although gut microbiota and early life events are likely involved in the development of irritable bowel syndrome (IBS), it remains unclear how these factors interact in the pathophysiology of IBS. In the present study, using rats subjected to maternal separation (MS) as a model of IBS, we investigated interrelationshi...

journal_title：Scientific reports

authors： Fukui H,Oshima T,Tanaka Y,Oikawa Y,Makizaki Y,Ohno H,Tomita T,Watari J,Miwa H

更新日期：2018-08-17 00:00:00

abstract：:There is widespread transcriptional dysregulation in Huntington's disease (HD) brain, but analysis is inevitably limited by advanced disease and postmortem changes. However, mutant HTT is ubiquitously expressed and acts systemically, meaning blood, which is readily available and contains cells that are dysfunctional i...

journal_title：Scientific reports

authors： Hensman Moss DJ,Flower MD,Lo KK,Miller JR,van Ommen GB,'t Hoen PA,Stone TC,Guinee A,Langbehn DR,Jones L,Plagnol V,van Roon-Mom WM,Holmans P,Tabrizi SJ

更新日期：2017-03-21 00:00:00

abstract：:Air pollution has aroused significant public concern in China, therefore, long-term air-quality data with high temporal and spatial resolution are needed to understand the variations of air pollution in China. However, the yearly variations with high spatial resolution of air quality and six air pollutants are still u...

journal_title：Scientific reports

authors： Guo H,Gu X,Ma G,Shi S,Wang W,Zuo X,Zhang X

更新日期：2019-10-23 00:00:00

abstract：:Circularly polarized laser sources with small footprints and high efficiencies can possess advanced functionalities in optical communication and biophotonic integrated systems. However, the conventional lasers with additional circular-polarization converters are bulky and hardly compatible with nanophotonic circuits, ...

journal_title：Scientific reports

authors： Liao WC,Liao SW,Chen KJ,Hsiao YH,Chang SW,Kuo HC,Shih MH

更新日期：2016-05-25 00:00:00

abstract：:Mutations in the Norrin (NDP) gene cause severe developmental blood vessel defects in the retina leading to congenital blindness. In the retina of Ndph-knockout mice only the superficial capillary network develops. Here, a detailed characterization of this mouse model at late stages of the disease using in vivo retina...

journal_title：Scientific reports

authors： Beck SC,Karlstetter M,Garcia Garrido M,Feng Y,Dannhausen K,Mühlfriedel R,Sothilingam V,Seebauer B,Berger W,Hammes HP,Seeliger MW,Langmann T

更新日期：2018-04-13 00:00:00

abstract：:In this work, we show that it is possible to overcome the limitations of solid-state MRI for rigid tissues due to large line broadening and short dephasing times by combining Magic Angle Spinning (MAS) with rotating pulsed field gradients. This allows recording ex vivo 31P 3D and 2D slice-selected images of rigid tiss...

journal_title：Scientific reports

authors： Yon M,Sarou-Kanian V,Scheler U,Bouler JM,Bujoli B,Massiot D,Fayon F

更新日期：2017-08-15 00:00:00

abstract：:We demonstrate a novel route to achieving highly efficient and strongly confined spoof surface plasmon polaritons (SPPs) waveguides at subwavelength scale enabled by planar staggered plasmonic waveguides (PSPWs). The structure of these new waveguides consists of an ultrathin metallic strip with periodic subwavelength ...

journal_title：Scientific reports

authors： Ye L,Xiao Y,Liu Y,Zhang L,Cai G,Liu QH

更新日期：2016-12-05 00:00:00

abstract：:With about 350 million people chronically infected around the world hepatitis B is a major health problem. Template for progeny HBV synthesis is the viral genome, organized as a minichromosome (cccDNA) inside the hepatocyte nucleus. How viral cccDNA gene expression is regulated by its chromatin structure; more importa...

journal_title：Scientific reports

authors： Alarcon V,Hernández S,Rubio L,Alvarez F,Flores Y,Varas-Godoy M,De Ferrari GV,Kann M,Villanueva RA,Loyola A

更新日期：2016-05-13 00:00:00

abstract：:Calcium ion is an intracellular messenger that plays a central role in signal transduction pathways. Calcineurin B-like proteins (CBLs) and CBL-interacting protein kinases (CIPKs) signal network have shown different functions in the Ca(2+) signaling process. In this work, we identified the entire soybean (Glycine max)...

journal_title：Scientific reports

authors： Zhu K,Chen F,Liu J,Chen X,Hewezi T,Cheng ZM

更新日期：2016-06-17 00:00:00

abstract：:The Xanthomonadaceae family consists of species of non-pathogenic and pathogenic γ-proteobacteria that infect different hosts, including humans and plants. In this study, we performed a comparative analysis using 69 fully sequenced genomes belonging to this family, with a focus on identifying proteins enriched in phyt...

journal_title：Scientific reports

authors： Assis RAB,Polloni LC,Patané JSL,Thakur S,Felestrino ÉB,Diaz-Caballero J,Digiampietri LA,Goulart LR,Almeida NF,Nascimento R,Dandekar AM,Zaini PA,Setubal JC,Guttman DS,Moreira LM

更新日期：2017-11-23 00:00:00

abstract：:In this study, 111 Cryptosporidium parvum IId isolates from several species of animals in China, Sweden, and Egypt were subtyped by multilocus sequence typing (MLST). One to eleven subtypes were detected at each of the 12 microsatellite, minisatellite, and single nucleotide polymorphism (SNP) loci, forming 25 MLST sub...

journal_title：Scientific reports

authors： Wang R,Zhang L,Axén C,Bjorkman C,Jian F,Amer S,Liu A,Feng Y,Li G,Lv C,Zhao Z,Qi M,Dong H,Wang H,Sun Y,Ning C,Xiao L

更新日期：2014-02-27 00:00:00

abstract：:Dectin-1, a classical pattern-recognition receptor, was now identified as an important regulator in immune homeostasis and cancer immunity through its extensive ligands binding functions and subsequent cytokines production. The aim of this study was to assess the clinical significance of dectin-1 expression in 290 pat...

journal_title：Scientific reports

authors： Xia Y,Liu L,Bai Q,Wang J,Xi W,Qu Y,Xiong Y,Long Q,Xu J,Guo J

更新日期：2016-09-07 00:00:00

abstract：:The gene PFKFB3 encodes for inducible 6-phosphofructo-2-kinase, a glycolysis-regulatory enzyme that protects against diet-induced intestine inflammation. However, it is unclear how nutrient overload regulates PFKFB3 expression and inflammatory responses in intestinal epithelial cells (IECs). In the present study, prim...

journal_title：Scientific reports

authors： Botchlett R,Li H,Guo X,Qi T,Zhao J,Zheng J,Woo SL,Pei Y,Liu M,Hu X,Chen G,Guo T,Yang S,Li Q,Xiao X,Huo Y,Wu C

更新日期：2016-07-08 00:00:00

abstract：:Siglec-2 undergoes constitutive endocytosis and is a drug target for autoimmune diseases and B cell-derived malignancies, including hairy cell leukaemia, marginal zone lymphoma, chronic lymphocytic leukaemia and non-Hodgkin's lymphoma (NHL). An alternative to current antibody-based therapies is the use of liposomal na...

journal_title：Scientific reports

authors： Madge PD,Maggioni A,Pascolutti M,Amin M,Waespy M,Bellette B,Thomson RJ,Kelm S,von Itzstein M,Haselhorst T

更新日期：2016-11-03 00:00:00

abstract：:According to the Source Monitoring Framework, the origin of a memory is remembered through the retrieval of specific features (e.g. perceptive, sensitive, affective signals). In two source discrimination tasks, we studied the ability of cuttlefish to remember the modality in which an item had been presented several ho...

journal_title：Scientific reports

authors： Billard P,Clayton NS,Jozet-Alves C

更新日期：2020-03-25 00:00:00

abstract：:The genesis of the hair follicle relies on signals derived from mesenchymal cells in the dermis during skin morphogenesis and regeneration. Multipotent skin-derived precursors (SKPs), which exhibit long term proliferation potential when being cultured in spheroids, have been shown to induce hair genesis and hair folli...

journal_title：Scientific reports

authors： Guo L,Wang X,Yuan J,Zhu M,Fu X,Xu RH,Wu C,Wu Y

更新日期：2019-02-27 00:00:00

abstract：:Stevia is a natural source of commercially important steviol glycosides (SGs), which share biosynthesis route with gibberellic acids (GAs) through plastidal MEP and cytosolic MVA pathways. Ontogeny-dependent deviation in SGs biosynthesis is one of the key factor for global cultivation of Stevia, has not been studied a...

journal_title：Scientific reports

authors： Singh G,Singh G,Singh P,Parmar R,Paul N,Vashist R,Swarnkar MK,Kumar A,Singh S,Singh AK,Kumar S,Sharma RK

更新日期：2017-09-19 00:00:00

abstract：:FTY-720 (Fingolimod) was one of the first compounds authorized for the treatment of multiple sclerosis. Among its other activities, this sphingosine analogue enhances exocytosis in neuroendocrine chromaffin cells, altering the quantal release of catecholamines. Surprisingly, the size of chromaffin granules is reduced ...

journal_title：Scientific reports

authors： Gimenez-Molina Y,García-Martínez V,Villanueva J,Davletov B,Gutiérrez LM

更新日期：2019-12-05 00:00:00

abstract：:GabR from Bacillus subtilis is a transcriptional regulator of the MocR subfamily of GntR regulators. The MocR architecture is characterized by the presence of an N-terminal winged-Helix-Turn-Helix domain and a C-terminal domain folded as the pyridoxal 5'-phosphate (PLP) dependent aspartate aminotransferase (AAT). The ...

journal_title：Scientific reports

authors： Frezzini M,Guidoni L,Pascarella S

更新日期：2019-12-17 00:00:00

abstract：:This study assessed the efficacy and tolerability of intravenous ibuprofen in the improvement of post-operative pain control and the reduction of opioid usage. Patients were randomly divided into placebo, ibuprofen 400 mg and ibuprofen 800 mg groups. All patients received patient-controlled intravenous morphine analge...

journal_title：Scientific reports

authors： Liu X,Wang X,Zhao W,Wei L,Zhang P,Han F

更新日期：2018-07-05 00:00:00

abstract：:Space radiation brings uneven damages to cells. The detection of the distribution of cell damage plays a very important role in radiation medicine and the related research. In this paper, a new hand-held microfluidic flow cytometer was developed to evaluate the degree of radiation damage of cells. The device we propos...

journal_title：Scientific reports

authors： Wang J,Fan Z,Zhao Y,Song Y,Chu H,Song W,Song Y,Pan X,Sun Y,Li D

更新日期：2016-03-17 00:00:00

abstract：:BK virus (BKV) associated nephropathy (BKVAN) is still an important cause of allograft dysfunction after kidney transplantation (KT). Recent data have shown that the new interferon (IFN)-λ family has been ascribed antiviral properties similar to IFNα, and that the response to IFNλ in kidney is restricted to epithelial...

journal_title：Scientific reports

authors： Dvir R,Paloschi V,Canducci F,Dell'Antonio G,Racca S,Caldara R,Pantaleo G,Clementi M,Secchi A

更新日期：2017-07-27 00:00:00

abstract：:The aim of this study was to develop a novel method to detect circulating histones H3 and H2B in plasma based on multiple reaction monitoring targeted mass spectrometry and a multiple reaction monitoring approach (MRM-MS) for its clinical application in critical bacteriaemic septic shock patients. Plasma samples from ...

journal_title：Scientific reports

authors： García-Giménez JL,Romá-Mateo C,Carbonell N,Palacios L,Peiró-Chova L,García-López E,García-Simón M,Lahuerta R,Gimenez-Garzó C,Berenguer-Pascual E,Mora MI,Valero ML,Alpízar A,Corrales FJ,Blanquer J,Pallardó FV

更新日期：2017-09-06 00:00:00

abstract：:HMG domain transcription factor, Sox2, is a critical gene for the development of cochlear hair cells, the receptor cells for hearing, but this has been ascribed to expansion of the progenitors that become hair cells. Here, we show that Sox2 activated Atoh1, a transcription factor important for hair cell differentiatio...

journal_title：Scientific reports

authors： Kempfle JS,Turban JL,Edge AS

更新日期：2016-03-18 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Sameni S,Malacrida L,Tan Z,Digman MA

更新日期：2018-04-11 00:00:00

abstract：:Pituitary adenylate cyclase activating polypeptide (PACAP) is a regulatory and cytoprotective neuropeptide, its deficiency implies accelerated aging in mice. It is present in the auditory system having antiapoptotic effects. Expression of Ca2+-binding proteins and its PAC1 receptor differs in the inner ear of PACAP-de...

journal_title：Scientific reports

authors： Fulop DB,Humli V,Szepesy J,Ott V,Reglodi D,Gaszner B,Nemeth A,Szirmai A,Tamas L,Hashimoto H,Zelles T,Tamas A

更新日期：2019-10-10 00:00:00

abstract：:Gene expression regulation is a complex and highly organized process involving a variety of genomic factors. It is widely accepted that differences in gene expression can contribute to the phenotypic variability between species, and that their interpretation can aid in the understanding of the physiologic variability....

journal_title：Scientific reports

authors： Dweep H,Kubikova N,Gretz N,Voskarides K,Felekkis K

更新日期：2015-07-16 00:00:00

abstract：:The increasing incidence of obesity accentuates the importance of identifying mechanisms and optimal therapeutic strategies for patients with heart failure (HF) in relation to obesity status. Here, we investigated the association between plasma level of apelin, an adipocyte-derived factor, and clinicopathological feat...

journal_title：Scientific reports

authors： Boal F,Roumegoux J,Alfarano C,Timotin A,Calise D,Anesia R,Drougard A,Knauf C,Lagente C,Roncalli J,Desmoulin F,Tronchere H,Valet P,Parini A,Kunduzova O

更新日期：2015-11-06 00:00:00

abstract：:The transfer of the flexor hallucis longus tendon or flexor digitorum longus tendon is frequently used for the treatment of posterior tibial tendon insufficiency or chronic Achilles tendinopathy. According to several anatomical studies, harvesting the flexor hallucis longus (FHL) tendon may cause nerve injury. Sixty-e...

journal_title：Scientific reports

authors： Mao H,Dong W,Shi Z,Yin W,Xu D,Wapner KL

更新日期：2017-10-27 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Motoki K,Sugiura M,Kawashima R

更新日期：2020-01-24 00:00:00