Serial transplantation of an HTLV-I-transformed hamster lymphoid cell line into hamsters.

abstract：:Breast cancer (BC) is the leading cause of cancer in sub-Saharan Africa (SSA) with rapidly increasing incidence rates reported in Uganda and Zimbabwe. However, the magnitude of these rising trends in premenopausal and postmenopausal women is unknown in most African countries. We used data from the African Cancer Regis...

journal_title：International journal of cancer

authors： Joko-Fru WY,Jedy-Agba E,Korir A,Ogunbiyi O,Dzamalala CP,Chokunonga E,Wabinga H,Manraj S,Finesse A,Somdyala N,Liu B,McGale P,Jemal A,Bray F,Parkin DM

更新日期：2020-10-15 00:00:00

abstract：:Tumor growth and metastasis of lacZ-transduced murine lymphoma ESbL cells inoculated into syngeneic DBA/2 mice are characterized by a transient plateau phase with a constant tumor diameter and low metastatic load, indicating a host response against the tumor. Here we show that endothelial cells participate in a T-cell...

journal_title：International journal of cancer

authors： Rocha M,Krüger A,Van Rooijen N,Schirrmacher V,Umansky V

更新日期：1995-11-03 00:00:00

abstract：:Several reports have suggested that one or both of the trinucleotide repeat polymorphisms in the human androgen receptor (hAR) gene, (CAG)n coding for polyglutamine and (GGC)n coding for polyglycine, may be associated with prostate cancer risk; but no study has investigated their association with disease progression. ...

journal_title：International journal of cancer

authors： Edwards SM,Badzioch MD,Minter R,Hamoudi R,Collins N,Ardern-Jones A,Dowe A,Osborne S,Kelly J,Shearer R,Easton DF,Saunders GF,Dearnaley DP,Eeles RA

更新日期：1999-10-22 00:00:00

abstract：:Normal sera of Japanese quails caused lysis of tumor cells from a Rous sarcoma virus (RSV)-induced quail tumor (QT cells). Other tumor cell lines, including RSV-transformed quail embryo cells and methylcholanthrene-induced quail tumors, were not lysed. This naturally occurring cytolytic factor (NCLF) was sensitive to ...

journal_title：International journal of cancer

authors： Yoshikawa Y,Yamanouchi K,Hishiyama M,Kobune K

更新日期：1978-05-15 00:00:00

abstract：:Antioxidants, primarily from fruits and vegetables, have been hypothesized to protect against non-Hodgkin lymphoma (NHL). The oxygen radical absorbance capacity (ORAC) assay, which measures total antioxidant capacity of individual foods and accounts for synergism, can be estimated using a food-frequency questionnaire ...

journal_title：International journal of cancer

authors： Holtan SG,O'Connor HM,Fredericksen ZS,Liebow M,Thompson CA,Macon WR,Micallef IN,Wang AH,Slager SL,Habermann TM,Call TG,Cerhan JR

更新日期：2012-09-01 00:00:00

abstract：:To assess whether there has been a change in histological features and prognostic factors of primary cutaneous malignant melanoma (CMM) in young individuals in Sweden, an unselected, population-based study was undertaken; 177 cases of primary CMM in persons below 20 years of age were reported to the Swedish National C...

journal_title：International journal of cancer

authors： Sander B,Karlsson P,Rosdahl I,Westermark P,Boeryd B

更新日期：1999-03-01 00:00:00

abstract：:Some herds of miniature swine are genetically predisposed to cutaneous melanoma. To test if swine melanoma susceptibility could be linked to the CDKN2A gene, which is involved in a proportion of 9p21-linked human familial melanoma, we performed a genetic analysis of miniature pigs of the MeLiM strain. F(1) and backcro...

journal_title：International journal of cancer

authors： Le Chalony C,Renard C,Vincent-Naulleau S,Crechet F,Leplat JJ,Tricaud Y,Horak V,Gruand J,Le Roy P,Frelat G,Geffrotin C

更新日期：2003-02-20 00:00:00

abstract：:Antibodies directed against idiotypic determinants of the cell-surface IgM of a B lymphoma, 38c, were effective in delaying development of the tumor and in some instances in preventing its growth. The efficacity of the anti-idiotype antibodies was markedly increased when they were injected in combination with anti-neo...

journal_title：International journal of cancer

authors： Hurwitz E,Burowski D,Kashi R,Hollander N,Haimovich J

更新日期：1986-05-15 00:00:00

abstract：:A novel non-phorbol-ester-like tumor promoter, okadaic acid (OA) has been shown to be an inhibitor of protein phosphatase I and IIA and, thus, to cause an "apparent activation" of protein kinase C (PKC). We previously showed that cis-diamminedichloroplatinum(II) (CDDP)-resistant cells, PC-9/CDDP, were cross-resistant ...

journal_title：International journal of cancer

authors： Nishio K,Sugimoto Y,Kasahara K,Fujiwara Y,Nishiwaki S,Fujiki H,Ohata M,Saijo N

更新日期：1992-02-01 00:00:00

abstract：:Peripheral blood T cells from a patient with T-cell chronic lymphocytic leukemia (T-CLL) failed to respond to mitogenic lectins or alloantigens but could be induced to proliferate by the addition of exogenous interleukin-2 (IL-2). The T-CLL cells also proliferated in response to 12-O-tetradecanoyl phorbol-13-acetate (...

journal_title：International journal of cancer

authors： Vyth-Dreese FA,de Vries JE

更新日期：1983-07-15 00:00:00

abstract：:The mode of transmission of human herpesvirus 8 (HHV8) was investigated in two seroepidemiological studies of Swedish women who completed a questionnaire about sexual behavior. Seropositivity for HHV8 antibodies, measured using an indirect immunofluorescence assay, was linked to a high number (>10) of sexual partners ...

journal_title：International journal of cancer

authors： Tedeschi R,Caggiari L,Silins I,Kallings I,Andersson-Ellström A,De Paoli P,Dillner J

更新日期：2000-07-15 00:00:00

abstract：:Over 10% of children with Wilms tumor (WT) have an underlying cancer predisposition syndrome (CPS). Cognizant of increasing demand for genetic evaluation and limited resources across health care settings, there is an urgent need to rationalize genetic referrals for this population. The McGill Interactive Pediatric Onc...

journal_title：International journal of cancer

authors： Cullinan N,Villani A,Mourad S,Somers GR,Reichman L,van Engelen K,Stephens D,Weksberg R,Foulkes WD,Malkin D,Grant R,Goudie C

更新日期：2020-02-15 00:00:00

abstract：:Responses to the genotoxic effect of bleomycin in lymphocytes of blood cultures, expressed as the average number of chromatid breaks per cell (b/c), varied from less than 0.20 to more than 2.00 in 335 normal individuals. More than 11% of the subjects tested showed a b/c rate above 1.00 and more than 22% showed a b/c r...

journal_title：International journal of cancer

authors： Hsu TC,Johnston DA,Cherry LM,Ramkissoon D,Schantz SP,Jessup JM,Winn RJ,Shirley L,Furlong C

更新日期：1989-03-15 00:00:00

abstract：:The active form of vitamin D(3), 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)), induces caspase-independent apoptosis in MCF-7 and T47D breast cancer cells. Before the appearance of apoptotic cells at Day 4 after the addition of 1,25(OH)(2)D(3), the MCF-7 cells are sensitized to the caspase-mediated apoptosis induced b...

journal_title：International journal of cancer

authors： Mathiasen IS,Hansen CM,Foghsgaard L,Jäättelä M

更新日期：2001-07-15 00:00:00

abstract：:Production of interleukin-6 (IL-6) by human pancreatic carcinoma cells inversely correlates with potentials for blood-borne metastasis to the liver in nude mice. IL-6 cDNA was transfected to PCI-43, one of our cultured pancreatic carcinoma cell lines that does not produce IL-6 and generates numerous metastases to the ...

journal_title：International journal of cancer

authors： Saito K,Ishikura H,Kishimoto T,Kawarada Y,Yano T,Takahashi T,Kato H,Yoshiki T

更新日期：1998-01-19 00:00:00

abstract：:Sexual behavior has been consistently identified as a major risk factor for cervical cancer. Population-based studies have demonstrated that risk related to sexual activity is mediated by human papillomavirus (HPV) infection. We conducted a case-control study of 199 cases with low-grade squamous intraepithelial lesion...

journal_title：International journal of cancer

authors： Kjaer SK,van den Brule AJ,Bock JE,Poll PA,Engholm G,Sherman ME,Walboomers JM,Meijer CJ

更新日期：1996-03-01 00:00:00

abstract：:Allelic loss at the short arm of chromosome 11 is one of the most common and potent events in the progression and metastasis of breast cancer. Here, we present evidence that the Integrin-Linked Kinase (ILK) gene maps to the commonly deleted chromosome 11p15.5 and suppresses malignant growth of human breast cancer cell...

journal_title：International journal of cancer

authors： Chen P,Shen WZ,Karnik P

更新日期：2004-10-10 00:00:00

abstract：:Infection of (C57BL/6 X DBA/2)F1 (BDF1) mice with 2,500 FFU of Friend virus complex (FV) resulted in erythroleukemia followed by recovery, at which time virus could not be detected in the spleens of mice, and with splenomegaly (progressor mice) or without splenomegaly (regressor mice). Progressor and regressor mice de...

journal_title：International journal of cancer

authors： Yoosook C

更新日期：1982-06-15 00:00:00

abstract：:The effect of EGF on the soft agar colony-forming ability of fresh human tumor cells was assessed in 40 specimens obtained from various types of carcinoma including those of the breast, endometrium ovary, and other sites. Cells from four established human tumor cell lines (three breast and one endometrial) were also i...

journal_title：International journal of cancer

authors： Pathak MA,Matrisian LM,Magun BE,Salmon SE

更新日期：1982-12-15 00:00:00

abstract：:Galectin-1 and galectin-3 are galactoside-binding proteins involved in different steps of tumor progression and potential targets for therapy. We have investigated the expression of these galectins in 38 human bladder transitional-cell carcinomas of different histological grade and clinical stage and in 5 normal uroth...

journal_title：International journal of cancer

authors： Cindolo L,Benvenuto G,Salvatore P,Pero R,Salvatore G,Mirone V,Prezioso D,Altieri V,Bruni CB,Chiariotti L

更新日期：1999-02-19 00:00:00

abstract：:Serum alkaline DNase activity (SADA) was investigated in rats receiving s.c. transplants of tumor cells sensitive or resistant to chemotherapy. Serum samples from each animal were collected before transplantation, during the development of tumors and after therapy. Within a few days after transplantation of both tumor...

journal_title：International journal of cancer

authors： Economidou-Karaoglou A,Brasseur F,Lans M,Taper HS,Roberfroid MB

更新日期：1989-05-15 00:00:00

abstract：:Effects of 12-O-tetradecanoyl phorbol 13-acetate (TPA) and the hepatic peroxisome proliferators (HPPs) clofibrate, methyl clofenapate (MCP), di(2-ethylhexyl)phthalate (DEHP) and mono(2-ethylhexyl)phthalate (MEHP) were studied in 2 gap junctional intercellular communication (GJIC) systems, metabolic cooperation in V79 ...

journal_title：International journal of cancer

authors： Cruciani V,Mikalsen SO,Vasseur P,Sanner T

更新日期：1997-10-09 00:00:00

abstract：:Aberrant DNA methylation is considered a major mechanism for silencing tumor suppressor genes in gastric cancer. We used CpG microarray and differential methylation hybridization strategies to identify potential tumor suppressor genes and recovered glutamate receptor, ionotropic, kainate 2 (GRIK2) as a novel epigeneti...

journal_title：International journal of cancer

authors： Wu CS,Lu YJ,Li HP,Hsueh C,Lu CY,Leu YW,Liu HP,Lin KH,Hui-Ming Huang T,Chang YS

更新日期：2010-06-01 00:00:00

abstract：:Prostate-specific antigen (PSA) is a serine protease secreted by prostatic epithelial cells and is widely used as a marker for prostate cancer. The tissue specificity of PSA makes it a potential target for active specific immunotherapy, especially in prostate cancer patients who have undergone prostatectomy and in who...

journal_title：International journal of cancer

authors： Hodge JW,Schlom J,Donohue SJ,Tomaszewski JE,Wheeler CW,Levine BS,Gritz L,Panicali D,Kantor JA

更新日期：1995-10-09 00:00:00

abstract：:This paper deals with a spontaneous malignant transformation in one of our XP fibroblast lines. This cell line, designated XP29MA, was derived from a 14-year-old boy who did not show skin tumors or precancerous alterations either at the time of clinical examination or when the biopsy was taken. We have compared the fo...

journal_title：International journal of cancer

authors： Thielmann HW,Fischer E,Dzarlieva RT,Komitowski D,Popanda O,Edler L

更新日期：1983-06-15 00:00:00

abstract：:Androgen deprivation therapy (ADT) remains a key approach in the treatment of prostate cancer (PCa). However, PCa inevitably relapses and becomes ADT resistant. Besides androgens, there is evidence that thyroid hormone thyroxine (T4) and its active form 3,5,3'-triiodo-L-thyronine (T3) are involved in the progression o...

journal_title：International journal of cancer

authors： Aksoy O,Pencik J,Hartenbach M,Moazzami AA,Schlederer M,Balber T,Varady A,Philippe C,Baltzer PA,Mazumder B,Whitchurch JB,Roberts CJ,Haitel A,Herac M,Susani M,Mitterhauser M,Marculescu R,Stangl-Kremser J,Hassler MR,Kr

更新日期：2021-02-01 00:00:00

abstract：:IL-10 mRNA expression and protein production in established melanoma cell lines and freshly cultured primary and metastatic melanoma cells was examined. The in situ distribution of IL-10 in native melanoma tissue was also investigated by immunohistochemistry in primary tumors, metastases, benign melanocytic nevi and n...

journal_title：International journal of cancer

authors： Dummer W,Bastian BC,Ernst N,Schänzle C,Schwaaf A,Bröcker EB

更新日期：1996-05-29 00:00:00

abstract：:9-cis-Retinoic acid (9cRA) and 1alpha,25-dihydroxyvitamin D3 (1,25D) show promise as potential chemopreventive agents. We examined 9cRA and 1,25D, alone and in combination, for their potential to inhibit carcinogen (NNK)-induced lung carcinogenesis in A/J mice. A/J mice (n=14/group) were treated with 9cRA (7.5, 15, or...

journal_title：International journal of cancer

authors： Mernitz H,Smith DE,Wood RJ,Russell RM,Wang XD

更新日期：2007-04-01 00:00:00

abstract：:We have previously reported that losses of genomic material from the long arm of chromosome 18 are frequent in atypical and anaplastic meningiomas but rare in benign meningiomas. In the present study, we have investigated a series of 37 meningiomas for mutation and expression of 4 tumor suppressor genes (MADH2, MADH4,...

journal_title：International journal of cancer

authors： Büschges R,Boström J,Wolter M,Blaschke B,Weber RG,Lichter P,Collins VP,Reifenberger G

更新日期：2001-05-15 00:00:00

abstract：:By serologic identification of antigens by recombinant expression cloning (SEREX) analysis using an autologous lung adenocarcinoma cell line, OU-LU-6, as a cDNA library source, we demonstrated that XAGE-1 was the dominant antigen recognized by serum from a patient. By immunoscreening, we obtained 38 positive cDNA clon...

journal_title：International journal of cancer

authors： Ali Eldib AM,Ono T,Shimono M,Kaneko M,Nakagawa K,Tanaka R,Noguchi Y,Nakayama E

更新日期：2004-02-10 00:00:00