A De novo Mutation in Dystrophin Causing Muscular Dystrophy in a Female Patient.

abstract：:Apolipoprotein (a) [Lp(a)] phenotypes of 69 myocardial infarction survivor and 56 stroke patients were reported and compared to those of 190 healthy Chinese. The results revealed that the distributions of apo(a) phenotype frequency in patients with cardio-cerebrovascular disease (CCVD) were different from those of con...

journal_title：Chinese medical journal

authors： Zhuang YY,Li JJ,Wang JJ

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:The most typical cardiac abnormality is conotruncal defects (CTDs) in patients with 22q11 deletion syndrome (22q11DS). HIRA (histone cell cycle regulator) gene, as one of the candidate genes located at the critical region of 22q11DS, was reported as possibly relevant to CTD in animal models. This study aimed...

journal_title：Chinese medical journal

authors： Ju ZR,Wang HJ,Ma XJ,Ma D,Huang GY

更新日期：2016-10-20 00:00:00

abstract：BACKGROUND:Stenting a bifurcation lesion is technically challenging. No study has reported the clinical outcome of a dedicated bifurcation stent in China. We aimed to analyze the safety and clinical outcome of a novel side branch ostial stent (BIGUARD) stent in treating coronary bifurcation lesions. METHODS:Forty-seve...

journal_title：Chinese medical journal

authors： Chen SL,Zhang JJ,Ye F

更新日期：2009-09-20 00:00:00

abstract：BACKGROUND:In a previous study, we demonstrated that ephrin-A2 and -A3 negatively regulate the growth of neural progenitor cells in the central nervous system. Adult mice deficient in ephrin-A2 and -A3 (A2(-/-)A3(-/-)) displayed active ongoing neurogenesis throughout the brain, and mice deficient in ephrin-A3 alone sho...

journal_title：Chinese medical journal

authors： Zhu R,Cho KS,Chen DF,Yang L

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Over 70% of the total tissue weight in the cartilage matrix consists of water, and the early-stage osteoarthritic cartilage is characterized by swelling. Water transport in the cartilage matrix and across the membranes of chondrocytes may be important in normal and pathological conditions of cartilage. The p...

journal_title：Chinese medical journal

authors： Meng JH,Ma XC,Li ZM,Wu DC

更新日期：2007-12-20 00:00:00

abstract：:The solid pseudopapillary tumors of the pancreas (SPTP) are rare tumors, which are commonly found in adolescent women. Radical surgical resection of the primary tumor or metastases is the standard treatment for SPTP and could achieve long-term survival. We reported a case of a 20-year-old female with multiple liver me...

journal_title：Chinese medical journal

authors： Li JX,Wu H,Huang JW,Prasoon P,Zeng Y

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Chronic liver diseases are a major burden in China. Alanine aminotransferase (ALT) can be used as an indicator of hepatocyte damage. In this study, we determined the prevalence and etiologies of elevated ALT in an adult population in Jilin, China. METHODS:A total of 4072 individuals aged between 18 and 79 y...

journal_title：Chinese medical journal

authors： Zhang H,Jiang YF,He SM,Sun J,Gu Q,Feng XW,DU B,Wang W,Shi XD,Wang CY,Zhang SQ,Li WY,Niu JQ

更新日期：2011-09-01 00:00:00

abstract：:198 preterm delivery placentas of 28 weeks to less than 37 weeks pregnancy were analyzed. Gross examination revealed that the differences of placenta previa and low implantation (2.91%), bipartate placenta and rupture of marginal sinus (0.97% respectively), large placenta (2.91%), short cord (4.85%), velamentous inser...

journal_title：Chinese medical journal

authors： Tang MY

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:Peutz-Jeghers syndrome (PJS) is an autosomal dominantly inherited disease. STK11/LKB1 gene germline mutations have been identified as responsible for PJS. In our study, we investigated the molecular basis of PJS and evaluated correlation between the STK11 mutations and the Chinese population. METHODS:We col...

journal_title：Chinese medical journal

authors： Zuo YG,Xu KJ,Su B,Ho MG,Liu YH

更新日期：2007-07-05 00:00:00

abstract：OBJECTIVE:To study the effect of pericardial devascularization combined with Latarjet's innervation on portal hypertension. METHODS:Forty-eight patients undergoing pericardial devascularization combined with Latarjet's innervation were compared with 57 patients with devascularization. Clinical results were evaluated b...

journal_title：Chinese medical journal

authors： Li S,Wu E,Huang J,Luo C

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Because no data regarding the comparison of crush stenting with paclitaxel (PES) or sirolimus eluting stents (SES) for coronary bifurcate lesions have been reported, we compared the clinical outcomes of these two types of stents. METHODS:Two hundred and thirty patients with 242 bifurcate lesions were enroll...

journal_title：Chinese medical journal

authors： Chen SL,Zhang JJ,Ye F,Chen YD,Zhu ZS,Lin S,Tian NL,Liu ZZ,Fang WY,Sun XW,Hu DY,Kwan TW

更新日期：2008-03-20 00:00:00

abstract：BACKGROUND:Idiopathic choroidal neovascularization (ICNV) is an uncommon disorder affecting primarily individuals younger than the age of 50 years. In CNV patients, no apparent cause can be determined. This study aimed to evaluate the functional and morphological change of the retina with ICNV in young adults. METHODS...

journal_title：Chinese medical journal

authors： Wang WQ,Liu HY,Lu FQ,Hu WT,Gong YY,Wu Y,Xu S,Wang WJ,Xu X,Wang FH,Sun XD

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:To study 4 cases of adult T-cell leukemia/lymphoma (ATLL) associated with cutaneous lesions for clinicopathology, immunophenotype, human T-cell leukemia/lymphoma virus type I (HTLV-I) provirus DNA and their ultrastructure. At the same time, HTLV-I provirus DNA of ATLL patients were also compared with 18 cases...

journal_title：Chinese medical journal

authors： Wang C,Yao Z,Liao J,Luo Y,Ma Y,Chen G,Zhu W

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Beta(2)-adrenoceptor (beta(2)AR) desensitization is a common problem in clinical practice. beta(2)AR desensitization proceeds by at least such three mechanisms as heterologous desensitization, homologous desensitization and a kind of agonist-induced rapid phosphorylation by a variety of serine/threonine kina...

journal_title：Chinese medical journal

authors： Liu H,Zhou LF,Zhang Q,Qian FH,Yin KS,Huang M,Zhang XL

更新日期：2008-02-20 00:00:00

abstract：BACKGROUND:Pulsed radiofrequency (PRF) is a minimally invasive interventional technique that provides a novel and effective treatment strategy for neuropathic pain (NP). PRF is advantageous because it does not damage nerves and avoids sensory loss after treatment. At present, animal studies have demonstrated that PRF i...

journal_title：Chinese medical journal

authors： Fu M,Meng L,Ren H,Luo F

更新日期：2019-07-20 00:00:00

abstract：:Cellular and humoral immune functions in Chinese hemophiliacs with and without human immunodeficiency virus (HIV) infection were compared with those of healthy controls. There was a significant increase in peripheral T8 cells and a significant decrease of peripheral T4 cells as well as the T4/T8 ratio in 3 hemophiliac...

journal_title：Chinese medical journal

authors： Tang DJ,Pang XG

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:Green tea has been shown to improve cholesterol metabolism in animal studies, but the molecular mechanisms underlying this function have not been fully understood. Long non-coding RNAs (lncRNAs) have recently emerged as a major class of regulatory molecules involved in a broad range of biological processes a...

journal_title：Chinese medical journal

authors： Liu G,Zheng X,Xu Y,Lu J,Chen J,Huang X

更新日期：2015-01-05 00:00:00

abstract：OBJECTIVE:To investigate the relationship between vascular endothelial growth factor C (VEGF-C) expression, VEGFR-3 expression, lymphangiogenesis and angiogenesis in human non-small cell lung cancer (NSCLC). METHODS:Seventy-six NSCLC samples were stained for VEGF-C, VEGFR-3 and CD34 with immunohistochemical methods. A...

journal_title：Chinese medical journal

authors： Li Q,Dong X,Gu W,Qiu X,Wang E

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Prostate specific membrane antigen (PSMA) can facilitate the growth, migration, and invasion of the LNCaP prostate cancer cell lines, but the underlying molecular mechanisms have not yet been clearly defined. Here, we investigated whether PSMA serves as a novel regulator of the phosphatidylinositol 3-kinase ...

journal_title：Chinese medical journal

authors： Guo Z,Lai Y,Du T,Zhang Y,Chen J,Bi L,Lin T,Liu H,Wang W,Xu K,Jiang C,Han J,Zhang C,Dong W,Huang J,Huang H

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:It is unclear whether a history of paroxysmal atrial fibrillation (PAF) would impact the effect of catheter ablation on persistent atrial fibrillation (AF). This study aimed to compare the effect of catheter ablation on persistent AF with and without a history of PAF. METHODS:One hundred and eighty-three pa...

journal_title：Chinese medical journal

authors： Miao CL,Yin XD,Dong JZ,Liu XP,Yu RH,Long DY,Tang RB,Sang CH,Ma CS

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Menopausal symptoms and sleep difficulty were physiological processes that were affected by genetic and other factors. This study was to investigate the prevalence of menopausal symptoms and sleep quality in menopausal transition (MT) and postmenopause (PM) women in Taiyuan, Shanxi. METHODS:A community-base...

journal_title：Chinese medical journal

authors： Zhang JP,Wang YQ,Yan MQ,Li ZA,Du XP,Wu XQ

更新日期：2016-04-05 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) contribute to tumorigenesis by acting as either oncogenes or tumor suppressor genes. In this study, we investigated the role of miR-145 in the pathogenesis of uveal melanoma. METHODS:Expression profiles of miRNAs in uveal melanoma were performed using Agilent miRNA array. Quantitative rea...

journal_title：Chinese medical journal

authors： Li Y,Huang Q,Shi X,Jin X,Shen L,Xu X,Wei W

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The mortality of stroke patients is strongly affected by medical complications. However, there are limited data investigating the effect of in-hospital medical complications on the dependency of stroke patients worldwide. We prospectively and systematically investigated the effect of medical complications on...

journal_title：Chinese medical journal

authors： Wang PL,Zhao XQ,DU WL,Wang AX,Ji RJ,Yang ZH,Wang CX,Liu LP,Wang YL,Ju Y,Wang YJ,China National Stroke Registry (CNSR) investigators.

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:The management strategies after acute myocardial infarction (AMI) have been evolving from simple supportive treatment to various protocols of thrombolytic therapies, and then to mechanical revascularization by balloon angioplasty in recent years. However, controversies still exist between which is the best tr...

journal_title：Chinese medical journal

authors： Lee SW,Chan HW,Lam L

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:Epinephrine has been used as a first-choice vasopressor drug for cardiac arrest (CA) since 1974. However, the administration of epinephrine is controversial. This study aims to compare the effects of Shen-Fu injection (SFI) and epinephrine on resuscitation outcomes in a porcine model of prolonged CA. METHOD...

journal_title：Chinese medical journal

authors： Yin W,Guo Z,Li C

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Although the early clinical outcomes of total knee arthroplasty (TKA) using minimally invasive surgery techniques have been widely described, data on the mid- to long-term outcomes are limited. We designed a retrospective study to compare the two most common TKA techniques - The modified quadriceps-sparing (...

journal_title：Chinese medical journal

authors： Huang AB,Wang HJ,Yu JK,Yang B,Ma D,Zhang JY

更新日期：2015-07-20 00:00:00

abstract：BACKGROUND:Development of vulnerable lesions is not limited to the target lesions, but a pan-coronary process. Such lesions are identified by positive remodeling (intravascular ultrasound (IVUS) and complex lesions (angiography)). The prevalence of lesions with vulnerable characteristics in patients with stable angina ...

journal_title：Chinese medical journal

authors： Sun L,Lü SZ,Jin ZN,Song XT

更新日期：2010-04-05 00:00:00

abstract：BACKGROUND:Cardiovascular diseases, especially coronary artery disease (CAD), are major causes of death in industrialized countries. Elevated concentrations of plasma homocysteine (Hcy) have been associated with an increased risk of CAD. Increased plasma levels of chemokine, characterized by their ability to induce mig...

journal_title：Chinese medical journal

authors： Wang G,Mao JM,Wang X,Zhang FC

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Programmed cell death 5 (PDCD5) is a novel apoptotic regulatory gene that promotes apoptosis in various tumor cells. Studies have shown that PDCD5 accelerates the apoptosis of synoviocytes in vitro, implying a potential role in rheumatoid arthritis (RA) pathogenesis. This study examined the expression of PDC...

journal_title：Chinese medical journal

authors： Wang JF,Guan ZP,Zhang SL,Pei Z,Chen YY,Pan H

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To analyze the effect and mechanism of hyperbaric oxygen (HBO) treatment for severe brain injury (SBI). METHODS:Fifty-five patients were divided into a treatment group of 35 patients and a control group of 20 patients. We observed the alterations of clinical, brain electric earth map (BEAM), endothelin (ET) ...

journal_title：Chinese medical journal

authors： Ren H,Wang W,Ge Z,Zhang J

更新日期：2001-04-01 00:00:00