Abstract：
BACKGROUND:Chronic liver diseases are a major burden in China. Alanine aminotransferase (ALT) can be used as an indicator of hepatocyte damage. In this study, we determined the prevalence and etiologies of elevated ALT in an adult population in Jilin, China. METHODS:A total of 4072 individuals aged between 18 and 79 years were first interviewed, and then underwent ultrasonography and blood tests. RESULTS:The prevalence of elevated ALT was 17.53%. The most noticeable risk factor for ALT elevation was non-alcoholic fatty liver disease (NAFLD) (accounting for 10.79%), metabolic syndrome (16.25%), or both (20.31%). The development of NAFLD occurred mostly in female peasants and small businessmen with increased income, age, fasting plasma glucose, body mass index, triglyceridemia, and low-density lipoprotein and decreased education level, high-density lipoprotein. Elevated ALT frequently occurred in low education level, male peasants and small businessmen with increased income, body mass index and triglyceride who had NAFLD and/or metabolic syndrome. However, elevated ALT with infection of hepatitis B or C virus was not associated with metabolic disorders, but rather with gender, occupation and increased age. CONCLUSION:The results from the current study demonstrate that elevated ALT is fairly high in the Northeast population (17.53%) and that the cause of its elevation is mostly due to NAFLD and metabolic syndrome.
journal_name
Chin Med J (Engl)journal_title
Chinese medical journalauthors
Zhang H,Jiang YF,He SM,Sun J,Gu Q,Feng XW,DU B,Wang W,Shi XD,Wang CY,Zhang SQ,Li WY,Niu JQsubject
Has Abstractpub_date
2011-09-01 00:00:00pages
2661-8issue
17eissn
0366-6999issn
2542-5641journal_volume
124pub_type
杂志文章abstract：BACKGROUND:Sinus of Valsalva aneurysm (SVA) is a rare anomaly and few large or long-term series are well established. This study was designed to review 33-year surgical experience of SVA in one center. METHODS:From August 1980 to December 2013, patients with SVA underwent surgical repair were retrospectively studied. ...
journal_title：Chinese medical journal
pub_type： 杂志文章
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journal_title：Chinese medical journal
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journal_title：Chinese medical journal
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journal_title：Chinese medical journal
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journal_title：Chinese medical journal
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pub_type： 杂志文章
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journal_title：Chinese medical journal
pub_type： 杂志文章,meta分析,评审
doi：
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journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
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doi：
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journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2010-02-20 00:00:00
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pub_type： 杂志文章
doi：
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journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2005-06-05 00:00:00
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journal_title：Chinese medical journal
pub_type： 杂志文章
doi：10.4103/0366-6999.238140
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journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
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pub_type： 杂志文章
doi：
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pub_type： 杂志文章
doi：
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doi：
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pub_type： 杂志文章,随机对照试验
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doi：
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journal_title：Chinese medical journal
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