Verteporfin inhibits growth of human glioma in vitro without light activation.

abstract：:Any processing delay between the two eyes can result in illusory 3D percepts for moving objects because of either changes in the pure disparities over time for disparity sensors or by changes to sensors that encode motion/disparity conjointly. This is demonstrated by viewing a fronto-parallel pendulum through a neutra...

journal_title：Scientific reports

authors： Reynaud A,Hess RF

更新日期：2017-07-17 00:00:00

abstract：:Macular edema due to neovascular age-related macular degeneration, diabetes or retinal vein occlusion can cause central vision loss. Intravitreal treatment with antibody-based biopharmaceutical compounds designed to neutralize vascular endothelial growth factor (VEGF) has proven to be an efficient strategy to ameliora...

journal_title：Scientific reports

authors： Sivertsen MS,Jørstad ØK,Grevys A,Foss S,Moe MC,Andersen JT

更新日期：2018-02-01 00:00:00

abstract：:Duchenne muscular dystrophy (DMD) is a uniformly fatal condition of striated muscle wasting resulting in premature death from respiratory and/or cardiac failure. Symptomatic therapy has prolonged survival by limiting deaths resulting from respiratory insufficiency, but there is currently no effective therapy for most ...

journal_title：Scientific reports

authors： Fischer KD,Heitzman JA,Townsend D

更新日期：2019-08-23 00:00:00

abstract：:A tetrameric N-acetyl galactosaminyl (GalNAc) peptidomimetic was constructed by N-acetylation of repeating proline-based hydroxamic acid units, followed by a convergent 'click chemistry' coupling. This novel glycopeptidomimetic was determined to effectively antagonize the interaction between a transmembrane hepatic le...

journal_title：Scientific reports

authors： Zhang HL,Zang Y,Xie J,Li J,Chen GR,He XP,Tian H

更新日期：2014-07-01 00:00:00

abstract：:Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (Nox) are an important family of catalytic enzymes that generate reactive oxygen species (ROS), which mediate the regulation of diverse cellular functions. Although phagocyte Nox2/gp91phox is closely associated with the activation of host innate immune respo...

journal_title：Scientific reports

authors： Kim JH,Lee J,Bae SJ,Kim Y,Park BJ,Choi JW,Kwon J,Cha GH,Yoo HJ,Jo EK,Bae YS,Lee YH,Yuk JM

更新日期：2017-07-25 00:00:00

abstract：:A tribochemistry-assisted method has been developed for nondestructive surface nanofabrication on GaAs. Without any applied electric field and post etching, hollow nanostructures can be directly fabricated on GaAs surfaces by sliding a SiO2 microsphere under an ultralow contact pressure in humid air. TEM observation o...

journal_title：Scientific reports

authors： Song C,Li X,Dong H,Yu B,Wang Z,Qian L

更新日期：2015-03-12 00:00:00

abstract：:Uncertainty in the form of risk or ambiguity can arise from the interaction with nature and other players, while strategic uncertainty arises only in interactions with others. Here, we systematically compare binary decisions between a safe option and a potentially higher paying but uncertain option in four experimenta...

journal_title：Scientific reports

authors： Chierchia G,Nagel R,Coricelli G

更新日期：2018-02-23 00:00:00

abstract：:The TMPRSS2:ERG gene fusion is one of a series of highly promising prostate cancer (PCa) biomarker alternatives to the controversial serum PSA. Current methods for detecting TMPRSS2:ERG are limited in terms of long processing time, high cost and the need for specialized equipment. Thus, there is an unmet need for less...

journal_title：Scientific reports

authors： Koo KM,Wee EJ,Mainwaring PN,Trau M

更新日期：2016-07-29 00:00:00

abstract：:Three carbapenem-resistant Escherichia coli were recovered from rectal swabs of different patients in a tertiary hospital and were found carrying bla NDM-4, an uncommon bla NDM variant. Genome sequences of the isolates were obtained using Illumina technology and the long-read MinION sequencer. The isolates belonged to...

journal_title：Scientific reports

authors： Zhang X,Feng Y,Zhou W,McNally A,Zong Z

更新日期：2018-01-10 00:00:00

abstract：:The search for green and sustainable modification method to produce durable bamboo materials remains a challenge in industry. Here, heat treatment in tung oil at 100-200 °C was employed to modify bamboo materials. Oil permeation and distribution in the structure of bamboo samples during heat treatment were explored. T...

journal_title：Scientific reports

authors： Tang T,Zhang B,Liu X,Wang W,Chen X,Fei B

更新日期：2019-09-06 00:00:00

abstract：:Liver resection remains the popular treatment for hepatocellular carcinoma (HCC). The aim of this study was to explore the alteration of immune cells in HCC patients with liver resections. Nineteen patients were included and their peripheral blood samples were taken before and after liver resections for immune-cell an...

journal_title：Scientific reports

authors： Lee WC,Wang YC,Cheng CH,Wu TH,Lee CF,Wu TJ,Chou HS,Chan KM

更新日期：2019-02-19 00:00:00

abstract：:Drug resistance is one of the leading causes of failed cancer therapy in the treatment of acute myeloid leukemia. Although the mechanisms of resistance are poorly understood, they may be related to the presence of leukemia stem cells (LSCs). Down-regulation of the miR-203 reportedly contributes to oncogenesis and chem...

journal_title：Scientific reports

authors： Zhang Y,Zhou SY,Yan HZ,Xu DD,Chen HX,Wang XY,Wang X,Liu YT,Zhang L,Wang S,Zhou PJ,Fu WY,Ruan BB,Ma DL,Wang Y,Liu QY,Ren Z,Liu Z,Zhang R,Wang YF

更新日期：2016-02-05 00:00:00

abstract：:Although the search for quantitative trait loci for behaviour remains a considerable challenge, the complicated genetic architecture of quantitative traits is beginning to be understood. The current project utilised heterogeneous stock (HS) male mice (n = 580) to investigate the genetic basis for brain weights, activi...

journal_title：Scientific reports

authors： Janecka M,Marzi SJ,Parsons MJ,Liu L,Paya-Cano JL,Smith RG,Fernandes C,Schalkwyk LC

更新日期：2017-02-01 00:00:00

abstract：:Traditional risk assessment and source apportionment of sediments based on bulk polycyclic aromatic hydrocarbons (PAHs) can introduce biases due to unknown aging effects in various sediments. We used a mild solvent (hydroxypropyl-β-cyclodextrin) to extract the bioavailable fraction of PAHs (a-PAHs) from sediment sampl...

journal_title：Scientific reports

authors： Yang X,Yu L,Chen Z,Xu M

更新日期：2016-03-15 00:00:00

abstract：:Flavonoids and lignans are polyphenol classes with anticarcinogenic activities against colorectal cancer (CRC). However, very limited epidemiological evidence exists on their effects on CRC prognosis. This study aimed to evaluate the association between flavonoid and lignan intakes with the risk of CRC recurrence and ...

journal_title：Scientific reports

authors： Zamora-Ros R,Guinó E,Alonso MH,Vidal C,Barenys M,Soriano A,Moreno V

更新日期：2015-09-15 00:00:00

abstract：:Cell motility requires the precise coordination of cell polarization, lamellipodia formation, adhesion, and force generation. LKB1 is a multi-functional serine/threonine kinase that associates with actin at the cellular leading edge of motile cells and suppresses FAK. We sought to understand how LKB1 coordinates these...

journal_title：Scientific reports

authors： Wilkinson S,Hou Y,Zoine JT,Saltz J,Zhang C,Chen Z,Cooper LA,Marcus AI

更新日期：2017-01-19 00:00:00

abstract：:A silica gel coated microsphere resonator is proposed and experimentally demonstrated for measurements of ammonia (NH3) concentration in air with ultra-high sensitivity. The optical properties of the porous silica gel layer change when it is exposed to low (parts per million (ppm)) and even ultra-low (parts per billio...

journal_title：Scientific reports

authors： Mallik AK,Farrell G,Liu D,Kavungal V,Wu Q,Semenova Y

更新日期：2018-01-26 00:00:00

abstract：:Despite growing acknowledgement of the role of oxidized fatty acids (oxFA) as cellular signaling molecules and in the pathogenesis of disease, developing methods to measure these species in biological samples has proven challenging. Here we describe a novel method utilizing HPLC-ESI-MS/MS to identify and quantify mult...

journal_title：Scientific reports

authors： Ahern KW,Serbulea V,Wingrove CL,Palas ZT,Leitinger N,Harris TE

更新日期：2019-08-01 00:00:00

abstract：:We present theoretical results on the high-temperature phase stability and phonon spectra of paramagnetic bcc iron which explicitly take into account many-body effects. Several peculiarities, including a pronounced softening of the [110] transverse (T1) mode and a dynamical instability of the bcc lattice in harmonic a...

journal_title：Scientific reports

authors： Leonov I,Poteryaev AI,Gornostyrev YN,Lichtenstein AI,Katsnelson MI,Anisimov VI,Vollhardt D

更新日期：2014-07-07 00:00:00

abstract：:Increasing population has posed insurmountable challenges to agriculture in the provision of future food security, particularly in the Middle East and North Africa (MENA) region where biophysical conditions are not well-suited for agriculture. Iran, as a major agricultural country in the MENA region, has long been in ...

journal_title：Scientific reports

authors： Mesgaran MB,Madani K,Hashemi H,Azadi P

更新日期：2017-08-09 00:00:00

abstract：:Male Wistar rats were exposed to herbicide, pendimethalin (PND) at varying oral doses of 62.5, 125 and 250 mg/kg b.w. for 14 days. Toxiological effects were assessed in terms of oxidative stress, DNA damage, histopathological alterations and induction of anti-inflammatory and apoptotic responses linked Bax, Bcl-2, IFN...

journal_title：Scientific reports

authors： Ahmad MI,Zafeer MF,Javed M,Ahmad M

更新日期：2018-11-20 00:00:00

abstract：:A crystalline solid exhibits thermally induced localised non-affine droplets in the absence of external stress. Here we show that upon an imposed shear, the size of these droplets grow until they percolate at a critical strain, well below the value at which the solid begins to yield. This critical point does not manif...

journal_title：Scientific reports

authors： Das T,Ganguly S,Sengupta S,Rao M

更新日期：2015-06-03 00:00:00

abstract：:Dementia is a major public health issue worldwide and chronic use of benzodiazepine, which is very frequent in northern countries, was found to be a risk factor of dementia. This work aims at evaluating the impact of a reduction in chronic use of benzodiazepine on the future burden of dementia in France. Using estimat...

journal_title：Scientific reports

authors： Jacqmin-Gadda H,Guillet F,Mathieu C,Helmer C,Pariente A,Joly P

更新日期：2020-09-04 00:00:00

abstract：:Our study focused on quantifying the alterations of streamflow at a weir site due to the construction of a mini-hydropower plant in the Gurugoda Oya (Sri Lanka), and evaluating the spatial responses of benthic macroinvertebrates to altered flow regime. The HEC-HMS 3.5 model was applied to the Gurugoda Oya sub-catchmen...

journal_title：Scientific reports

authors： Munasinghe DSN,Najim MMM,Quadroni S,Musthafa MM

更新日期：2021-01-12 00:00:00

abstract：:Tin selenide has attracted much research interest due to its unprecedentedly high thermoelectric figure of merit (ZT). For real applications, it is desirable to increase the ZT value in the lower-temperature range, as the peak ZT value currently exists near the melting point. It is shown in this paper that the structu...

journal_title：Scientific reports

authors： Yu H,Dai S,Chen Y

更新日期：2016-05-19 00:00:00

abstract：:Alternative oxidase (AOX) is a mitochondrial inner-membrane oxidase that accepts electrons directly from ubiquinol and reduces oxygen to water without involving cytochrome-linked electron transport chain. It is highly conserved in many non-vertebrate taxa and may protect cells against hypoxia and oxidative stress. We ...

journal_title：Scientific reports

authors： Liu M,Guo X

更新日期：2017-09-07 00:00:00

abstract：:Short-range interaction can give rise to particle pairing with a short-range correlation, which may be destroyed in the presence of an external field. We study the transition between correlated and uncorrelated particle states in the framework of one- dimensional Hubbard model driven by a field. We show that the long ...

journal_title：Scientific reports

authors： Zhang XZ,Lin S,Song Z

更新日期：2016-06-02 00:00:00

abstract：:Adipose tissue inflammation is a central pathological element that regulates obesity-mediated insulin resistance and type II diabetes. Evidence demonstrates that extracellular signal-regulated kinase (ERK 1/2) activation (i.e. phosphorylation) links tumor necrosis factor α (TNFα) to pro-inflammatory gene expression in...

journal_title：Scientific reports

authors： Habibian JS,Jefic M,Bagchi RA,Lane RH,McKnight RA,McKinsey TA,Morrison RF,Ferguson BS

更新日期：2017-10-10 00:00:00

abstract：:Western wheatgrass (Pascopyrum smithii Rydb.) is an important cool-season forage and turfgrass. However, due to seed dormancy and poor seedling vigor, it is difficult to develop high seed yield production systems, and assessing these components in response to seed yield. Based on multifactor orthogonally designed fiel...

journal_title：Scientific reports

authors： Chen Z,Niu J,Cao X,Jiang W,Cui J,Wang Q,Zhang Q

更新日期：2019-11-29 00:00:00

abstract：:Knowledge about a tool's dynamics can be acquired from the visual configuration of the tool and through physical interaction. Here, we examine how visual information affects the generalization of dynamic learning during tool use. Subjects rotated a virtual hammer-like object while we varied the object dynamics separat...

journal_title：Scientific reports

authors： Sadeghi M,Sheahan HR,Ingram JN,Wolpert DM

更新日期：2019-02-25 00:00:00