Abstract：
:Knowledge about a tool's dynamics can be acquired from the visual configuration of the tool and through physical interaction. Here, we examine how visual information affects the generalization of dynamic learning during tool use. Subjects rotated a virtual hammer-like object while we varied the object dynamics separately for two rotational directions. This allowed us to quantify the coupling of adaptation between the directions, that is, how adaptation transferred from one direction to the other. Two groups experienced the same dynamics of the object. For one group, the object's visual configuration was displayed, while for the other, the visual display was uninformative as to the dynamics. We fit a range of context-dependent state-space models to the data, comparing different forms of coupling. We found that when the object's visual configuration was explicitly provided, there was substantial coupling, such that 31% of learning in one direction transferred to the other. In contrast, when the visual configuration was ambiguous, despite experiencing the same dynamics, the coupling was reduced to 12%. Our results suggest that generalization of dynamic learning of a tool relies, not only on its dynamic behaviour, but also on the visual configuration with which the dynamics is associated.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Sadeghi M,Sheahan HR,Ingram JN,Wolpert DMdoi
10.1038/s41598-019-39507-5subject
Has Abstractpub_date
2019-02-25 00:00:00pages
2731issue
1issn
2045-2322pii
10.1038/s41598-019-39507-5journal_volume
9pub_type
杂志文章abstract：:The near complete genome sequences of ten field avian orthoreovirus (ARV) strains collected from young chicken between 2002 and 2011 in Hungary have been determined in order to explore the genetic diversity and evolutionary mechanisms affecting ARVs in this region. Sequence analyses and phylogenetic calculations revea...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep36960
更新日期：2016-11-10 00:00:00
abstract：:Insecticides are the main method of controlling lepidopteran pests of eucalyptus plantations and those selective to natural enemies, such as the endoparasitoid Palmistichus elaeisis Delvare et LaSalle (Hymenoptera: Eulophidae), are preferable. The objective of this study was to evaluate the selectivity and effects on ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-69200-x
更新日期：2020-07-24 00:00:00
abstract：:The serotonin transporter (SERT) is an integral membrane protein that exploits preexisting sodium-, chloride-, and potassium ion gradients to catalyze the thermodynamically unfavorable movement of synaptic serotonin into the presynaptic neuron. SERT has garnered significant clinical attention partly because it is the ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep23789
更新日期：2016-04-01 00:00:00
abstract：:Tyrosine hydroxylase (TH), the initial enzyme in the melanin pathway, catalyzes tyrosine conversion into Dopa. Although expression and regulation of TH have been shown to affect cuticle pigmentation in insects, no direct functional studies to date have focused on the specific physiological processes involving the enzy...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep29835
更新日期：2016-07-15 00:00:00
abstract：:Information spreading in complex networks is often modeled as diffusing information with certain probability from nodes that possess it to their neighbors that do not. Information cascades are triggered when the activation of a set of initial nodes - seeds - results in diffusion to large number of nodes. Here, several...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-00937-8
更新日期：2017-04-18 00:00:00
abstract：:Although it has been reported that uterine signal transducer and activator of transcription 3 (STAT3) is essential for embryo implantation, the exact roles of uterine epithelial and stromal STAT3 on embryo implantation have not been elucidated. To address this issue, we generated Stat3-floxed/Ltf-iCre (Stat3-eKO), Sta...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-72640-0
更新日期：2020-09-23 00:00:00
abstract：:Fluid-feeding insects have evolved a unique strategy to distribute the labor between a liquid-acquisition device (proboscis) and a sucking pump. We theoretically examined physical constraints associated with coupling of the proboscis and sucking pump into a united functional organ. Classification of fluid feeders with...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-06391-w
更新日期：2017-07-26 00:00:00
abstract：:The pathogenesis of glioblastoma (GBM) is characterized by highly invasive behavior allowing dissemination and progression. A conclusive image of the invasive process is not available. The aim of this work was to study invasion dynamics in GBM using an innovative in vivo imaging approach. Primary brain tumor initiatin...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-38625-4
更新日期：2019-02-14 00:00:00
abstract：:Although early diagnosis and treatment reduce the risk of blindness from glaucoma, the decision on whether or not to begin treatment in patients with suspected glaucoma is often a dilemma because the majority of patients never develop definite glaucoma. A growing body of evidences suggests that posterior bowing of the...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-17843-8
更新日期：2018-01-15 00:00:00
abstract：:In vitro amplification assays, such as real-time quaking-induced conversion (RT-QuIC) are used to detect aggregation activity of misfolded prion protein (PrP) in brain, cerebrospinal fluid (CSF) and urine samples from patients with a prion disease. We believe that the method also has a much broader application spectru...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep28711
更新日期：2016-07-07 00:00:00
abstract：:Bats are an important reservoir for zoonotic viruses. To date, only three RVA strains have been reported in bats in Kenya and China. In the current study we investigated the genetic diversity of RVAs in fecal samples from 87 straw-colored fruit bats living in close contact with humans in Cameroon using viral metagenom...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep34209
更新日期：2016-09-26 00:00:00
abstract：:The work describes the development of a flexible, hydrogel embedded pH-sensor that can be integrated in inexpensive wearable and non-invasive devices at epidermal level for electrochemical quantification of H+ ions in sweat. Such a device can be useful for swift, real time diagnosis and for monitoring specific conditi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-45399-2
更新日期：2019-06-20 00:00:00
abstract：:To investigate the prognostic role of the estrogen receptor (ER) in gastric cancer (GC) patients, tumor tissues from 932 patients with advanced GC were assessed for ER expression using immunohistochemistry, and their clinicopathologic features were evaluated. Forty patients (4.3%) had ER expression and they were more ...
journal_title：Scientific reports
pub_type： 临床试验,杂志文章
doi：10.1038/srep07592
更新日期：2014-12-23 00:00:00
abstract：:We analysed suppressive effects of potassium (K) fertilisation on radiocesium (137Cs) uptake by hinoki cypress (Chamaecyparis obtusa) seedlings from soils contaminated after the Fukushima Daiichi Nuclear Power Plant accident. Three-year-old seedlings were planted in a clear-cut forest (ca. 4 ha) during June-July 2014,...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-15401-w
更新日期：2017-11-15 00:00:00
abstract：:Pulmonary tuberculosis (PTB) results in lung functional impairment and there are no surrogate markers to monitor the extent of lung involvement. We investigated the clinical significance of S100A12 and soluble receptor for advanced glycation end-products (sRAGE) for predicting the extent of lung involvement. We perfor...
journal_title：Scientific reports
pub_type： 临床试验,杂志文章
doi：10.1038/srep31798
更新日期：2016-08-19 00:00:00
abstract：:The limits of mammography have led to an increasing interest on possible alternatives such as the breast Computed Tomography (bCT). The common goal of all X-ray imaging techniques is to achieve the optimal contrast resolution, measured through the Contrast to Noise Ratio (CNR), while minimizing the radiological risks,...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-49351-2
更新日期：2019-09-11 00:00:00
abstract：:Assembly of nanowires into ordered macroscopic structures with new functionalities has been a recent focus. In this Letter, we report a new route for ordering hydrophilic Ag nanowires with high aspect ratio by flowing through a glass capillary. The present glass capillary with well-defined silver nanowire films inside...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep00987
更新日期：2012-01-01 00:00:00
abstract：:Biofilm is recognized as a contributing factor to the capacity of Acinetobacter baumannii to persist and prosper in medical settings, but it is still unknown whether biofilms contribute to the spread of A. baumannii. In this study, the biofilm formation of 114 clinical A. baumannii isolates and 32 non-baumannii Acinet...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep32066
更新日期：2016-08-25 00:00:00
abstract：:Haber-Bosch nitrogen (N) has been increasingly used in industrial products, e.g., nylon, besides fertilizer. Massive numbers of species of industrial reactive N (Nr) have emerged and produced definite consequences but receive little notice. Based on a comprehensive inventory, we show that (1) the industrial N flux has...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep02579
更新日期：2013-01-01 00:00:00
abstract：:R.PabI is a type II restriction enzyme that recognizes the 5'-GTAC-3' sequence and belongs to the HALFPIPE superfamily. Although most restriction enzymes cleave phosphodiester bonds at specific sites by hydrolysis, R.PabI flips the guanine and adenine bases of the recognition sequence out of the DNA helix and hydrolyz...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep35197
更新日期：2016-10-12 00:00:00
abstract：:Crotoxin (CTX) is the primary toxin of South American rattlesnake Crotalus durissus terrificus venom. CTX reduces tumour mass, and tumour cell proliferation and these effects seem to involve the formation of new vessels. Angiogenesis has a key role in tumour growth and progression and is regulated by macrophage secret...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-40903-0
更新日期：2019-03-12 00:00:00
abstract：:The studies investigating the effects of green tea on blood pressure (BP) have generated inconsistent results. The aim of this study is to quantitatively evaluate the effects of green tea on BP control. PubMed, Embase, and the Cochrane Library (updated to March 2014) were searched for randomized controlled trials eval...
journal_title：Scientific reports
pub_type： 杂志文章,meta分析
doi：10.1038/srep06251
更新日期：2014-09-01 00:00:00
abstract：:Studies of past human-landscape interactions rely upon the integration of archaeological, biological and geological information within their geographical context. However, detecting the often ephemeral traces of human activities at a landscape scale remains difficult with conventional archaeological field survey. Geop...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep01517
更新日期：2013-01-01 00:00:00
abstract：:Bt cotton was genetically modified to produce insecticidal proteins targeting Lepidopteran pests and is therefore only minimally affected by caterpillar damage. This could lead to reduced levels of inherent, systemically inducible defensive compounds in Bt cotton which might benefit other important cotton herbivores s...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-38917-9
更新日期：2019-02-25 00:00:00
abstract：:Facial emotion perception plays a key role in interpersonal communication and is a precursor for a variety of socio-cognitive abilities. One brain region thought to support emotion perception is the inferior frontal cortex (IFC). The current study aimed to examine whether modulating neural activity in the IFC using hi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-11578-2
更新日期：2017-09-12 00:00:00
abstract：:During cryopreservation, ice recrystallization is a major cause of cellular damage. Conventional cryoprotectants such as dimethyl sulfoxide (DMSO) and glycerol function by a number of different mechanisms but do not mitigate or control ice recrystallization at concentrations utilized in cryopreservation procedures. In...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep23619
更新日期：2016-03-29 00:00:00
abstract：:The presence of hepatic steatosis (HS) is an important histological feature in a variety of liver disease. It is critical to assess HS accurately, particularly where it plays an integral part in defining the disease. Conventional methods of quantifying HS remain semi-quantitative, with potential limitations in precisi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-39783-1
更新日期：2019-02-27 00:00:00
abstract：:Glomerular permeability and subsequent albuminuria are early clinical markers for glomerular injury in hypertensive nephropathy. Albuminuria predicts mortality and cardiovascular morbidity. AT1 receptor blockers protect from albuminuria, cardiovascular morbidity and mortality. A blood pressure independent, molecular m...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep39513
更新日期：2016-12-22 00:00:00
abstract：:The dynamics of cell wall polysaccharides may modulate the cell wall mechanics and thus control the expansion growth of plant cells. The unique composition of type II primary cell wall characteristic of grasses suggests that they employ specific mechanisms for cell enlargement. We characterized the transcriptomes in f...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-67782-0
更新日期：2020-07-02 00:00:00
abstract：:To increase the yield potential while limiting the environmental impact of N management practices is an important issue in rice cultivation. The large-grain rice cultivar Akita 63 showed higher N-use efficiency for grain production. To elucidate this, we analyzed yield characteristics of Akita 63 in comparison with th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-69289-0
更新日期：2020-07-22 00:00:00
