The application of polysaccharide-based nanogels in peptides/proteins and anticancer drugs delivery.


:Finding adequate carriers for proteins/peptides and anticancer drugs delivery has become an urgent need, owing to the growing number of therapeutic macromolecules and the increasing amount of cancer incidence. Polysaccharide-based nanogels have attracted interest as carriers for proteins/peptides and anticancer drugs because of their characteristic properties like biodegradability, biocompatibility, stimuli-responsive behaviour, softness and swelling to help achieve a controlled, triggered response at the target site. In addition, the groups of the polysaccharide backbone are able to be modified to develop functional nanogels. Some polysaccharides have the intrinsic ability to recognise specific cell types, allowing the design of targeted drug delivery systems through receptor-mediated endocytosis. This review is aimed at describing and exploring the potential of polysaccharides that are used in nanogels which can help to deliver proteins/peptides and anticancer drugs.


J Drug Target


Zhang L,Pan J,Dong S,Li Z




Has Abstract


2017-09-01 00:00:00












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  • Effective photothermal chemotherapy with docetaxel-loaded gold nanospheres in advanced prostate cancer.

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    authors: Shen Y,Ma Z,Chen F,Dong Q,Hu Q,Bai L,Chen J

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  • Interaction of serum components with poly(methylmethacrylate) nanoparticles and the resulting body distribution after intravenous injection in rats.

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    journal_title:Journal of drug targeting

    pub_type: 杂志文章


    authors: Borchard G,Kreuter J

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    journal_title:Journal of drug targeting

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    更新日期:2013-12-01 00:00:00

  • Stability issues and approaches to stabilised nanoparticles based drug delivery system.

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    journal_title:Journal of drug targeting

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    更新日期:2020-06-01 00:00:00

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    journal_title:Journal of drug targeting

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    journal_title:Journal of drug targeting

    pub_type: 杂志文章


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    journal_title:Journal of drug targeting

    pub_type: 杂志文章


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  • Biphasic interactions between a cationic dendrimer and actin.

    abstract::Gene delivery systems face the problem not only of the route toward the cell and tissues in question, but also of the molecularly crowded environment of both the cytoplasm and the nucleus itself. One of the physical barriers in the cytoplasm for diffusing nanoparticles is an actin network. Here, we describe the findin...

    journal_title:Journal of drug targeting

    pub_type: 杂志文章


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    更新日期:2010-12-01 00:00:00

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    pub_type: 杂志文章


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  • Polymersomes as an effective drug delivery system for glioma--a review.

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    pub_type: 杂志文章


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    journal_title:Journal of drug targeting

    pub_type: 杂志文章


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    pub_type: 杂志文章


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    pub_type: 杂志文章,收录出版


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    pub_type: 杂志文章


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    pub_type: 杂志文章


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    pub_type: 杂志文章,评审


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    pub_type: 杂志文章


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    pub_type: 杂志文章


    authors: Li Z,Zheng Z,Li C,Li Z,Wu J,Zhang B

    更新日期:2020-08-01 00:00:00

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    journal_title:Journal of drug targeting

    pub_type: 杂志文章


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    journal_title:Journal of drug targeting

    pub_type: 杂志文章,评审


    authors: Shende P,Patel C

    更新日期:2019-02-01 00:00:00

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    journal_title:Journal of drug targeting

    pub_type: 杂志文章


    authors: Değim T,Eğlen B,Ocak O

    更新日期:2006-01-01 00:00:00

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    journal_title:Journal of drug targeting

    pub_type: 杂志文章


    authors: Nakakura M,Terajima M,Kato Y,Hayakawa E,Ito K,Kuroda T

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    journal_title:Journal of drug targeting

    pub_type: 杂志文章


    authors: Kodama Y,Ohkubo C,Kurosaki T,Egashira K,Sato K,Fumoto S,Nishida K,Higuchi N,Kitahara T,Nakamura T,Sasaki H

    更新日期:2015-01-01 00:00:00

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    journal_title:Journal of drug targeting

    pub_type: 杂志文章


    authors: Hattori Y,Nakamura M,Takeuchi N,Tamaki K,Shimizu S,Yoshiike Y,Taguchi M,Ohno H,Ozaki KI,Onishi H

    更新日期:2019-02-01 00:00:00

  • Muco-adhesive multivesicular liposomes as an effective carrier for transmucosal insulin delivery.

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    journal_title:Journal of drug targeting

    pub_type: 杂志文章


    authors: Jain AK,Chalasani KB,Khar RK,Ahmed FJ,Diwan PV

    更新日期:2007-07-01 00:00:00

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    journal_title:Journal of drug targeting

    pub_type: 杂志文章,评审


    authors: Huey R,Hawthorne S,McCarron P

    更新日期:2017-06-01 00:00:00