Lsh/HELLS regulates self-renewal/proliferation of neural stem/progenitor cells.

abstract：:Long-term monitoring of host-parasite interactions is important for understanding the consequences of infection on host fitness and population dynamics. In an eight-year survey of the loggerhead sea turtle (Caretta caretta) population nesting in Cabo Verde, we determined the spatiotemporal variation of Ozobranchus mar...

journal_title：Scientific reports

authors： Lockley EC,Fouda L,Correia SM,Taxonera A,Nash LN,Fairweather K,Reischig T,Durão J,Dinis H,Roque SM,Lomba JP,Dos Passos L,Cameron SJK,Stiebens VA,Eizaguirre C

更新日期：2020-10-29 00:00:00

abstract：:The relationships between polypeptide composition, sequence, structure and function have been puzzling biologists ever since first protein sequences were determined. Here, we study the statistics of occurrence of all possible pentapeptide sequences in known proteins. To compensate for the non-uniform distribution of i...

journal_title：Scientific reports

authors： Poznański J,Topiński J,Muszewska A,Dębski KJ,Hoffman-Sommer M,Pawłowski K,Grynberg M

更新日期：2018-10-11 00:00:00

abstract：:Ancestry informative single nucleotide polymorphisms (SNPs) can identify biogeographic ancestry (BGA); however, population substructure and relatively recent admixture can make differentiation difficult in heterogeneous Hispanic populations. Utilizing unrelated individuals from the Genomic Origins and Admixture in Lat...

journal_title：Scientific reports

authors： Setser CH,Planz JV,Barber RC,Phillips NR,Chakraborty R,Cross DS

更新日期：2020-05-08 00:00:00

abstract：:A low-cost compact planar leaky-wave antenna (LWA) is proposed offering directive broadside radiation over a significantly wide bandwidth. The design is based on an annular metallic strip grating (MSG) configuration, placed on top of a dual-layer grounded dielectric substrate. This defines a new two-layer parallel-pla...

journal_title：Scientific reports

authors： Comite D,Podilchak SK,Baccarelli P,Burghignoli P,Galli A,Freundorfer AP,Antar YMM

更新日期：2018-12-10 00:00:00

abstract：:Antigens from Mycobacterium tuberculosis (M.tb), have been shown to stimulate human B cell responses to unrelated recall antigens in vitro. However, it is not known whether natural M.tb infection or whether vaccination with, Mycobacterium bovis BCG, has a similar effect. This study investigated the effects of M.tb inf...

journal_title：Scientific reports

authors： Kimuda SG,Andia-Biraro I,Sebina I,Egesa M,Nalwoga A,Smith SG,Bagaya BS,Levin J,Elliott AM,Raynes JG,Cose S

更新日期：2020-08-31 00:00:00

abstract：:Stable isotopes in water (e.g., δ2H and δ18O) are important indicators of hydrological and ecological patterns and processes. Tap water can reflect integrated features of regional hydrological processes and human activities. China is a large country with significant meteorological and geographical variations. This rep...

journal_title：Scientific reports

authors： Zhao S,Hu H,Tian F,Tie Q,Wang L,Liu Y,Shi C

更新日期：2017-03-02 00:00:00

abstract：:Oxygen tolerance of selenium-containing [NiFeSe] hydrogenases (Hases) is attributable to the high reducing power of the selenocysteine residue, which sustains the bimetallic Ni-Fe catalytic center in the large subunit. Genes encoding [NiFeSe] Hases are inherited by few sulphate-reducing δ-proteobacteria globally distr...

journal_title：Scientific reports

authors： Tamura T,Tsunekawa N,Nemoto M,Inagaki K,Hirano T,Sato F

更新日期：2016-01-28 00:00:00

abstract：:2D transition metal dichalcogenides (TMDs) have attracted a lot of attention recently for energy-efficient tunneling-field-effect transistor (TFET) applications due to their excellent gate control resulting from their atomically thin dimensions. However, most TMDs have bandgaps (Eg) and effective masses (m(*)) outside...

journal_title：Scientific reports

authors： Ameen TA,Ilatikhameneh H,Klimeck G,Rahman R

更新日期：2016-06-27 00:00:00

abstract：:The combined regulation of a network of inhibitory and activating T cell receptors may be a critical step in the development of chronic HCV infection. Ex vivo HCV MHC class I + II tetramer staining and bead-enrichment was performed with baseline and longitudinal PBMC samples of a cohort of patients with acute, chronic...

journal_title：Scientific reports

authors： Ackermann C,Smits M,Woost R,Eberhard JM,Peine S,Kummer S,Marget M,Kuntzen T,Kwok WW,Lohse AW,Jacobs T,Boettler T,Schulze Zur Wiesch J

更新日期：2019-07-23 00:00:00

abstract：:Insect pheromones offer potential for managing pests of crop plants. Volatility and instability are problems for deployment in agriculture but could be solved by expressing genes for the biosynthesis of pheromones in the crop plants. This has now been achieved by genetically engineering a hexaploid variety of wheat to...

journal_title：Scientific reports

authors： Bruce TJA,Aradottir GI,Smart LE,Martin JL,Caulfield JC,Doherty A,Sparks CA,Woodcock CM,Birkett MA,Napier JA,Jones HD,Pickett JA

更新日期：2015-06-25 00:00:00

abstract：:Propylea japonica (Thunberg) (Coleoptera: Coccinellidae) is a prevalent pollen consumer in corn fields and is therefore exposed to insecticidal proteins contained in the pollen of insect-resistant transgenic corn cultivars expressing Cry proteins derived from Bacillus thuringiensis (Bt). In the present study, the pote...

journal_title：Scientific reports

authors： Liu Y,Liu Q,Wang Y,Chen X,Song X,Romeis J,Li Y,Peng Y

更新日期：2016-03-23 00:00:00

abstract：:Pharmacological activities of some natural products diminish and even disappear after purification. In this study, we explored the mechanisms underlying the decrease of acute oral toxicity of Coptidis Rhizoma extract after purification. The water solubility, in vitro absorption, and plasma exposure of berberine (the m...

journal_title：Scientific reports

authors： Ma BL,Yin C,Zhang BK,Dai Y,Jia YQ,Yang Y,Li Q,Shi R,Wang TM,Wu JS,Li YY,Lin G,Ma YM

更新日期：2016-01-29 00:00:00

abstract：:Several studies have shown that the 'poor' sperm DNA quality appears to be an important factor affecting male reproductive ability. In the case of sperm cells from males with the correct somatic karyotype but with deficient spermatogenesis, resulting in a high degree of sperm DNA fragmentation, we observed changes in ...

journal_title：Scientific reports

authors： Wiland E,Fraczek M,Olszewska M,Kurpisz M

更新日期：2016-08-25 00:00:00

abstract：:Ionotropic activation of NMDA receptors (NMDARs) requires agonist glutamate and co-agonist glycine. Here we show that glycine enhances the activation of cell survival-promoting kinase Akt in cultured cortical neurons in which both the channel activity of NMDARs and the glycine receptors are pre-inhibited. The effect o...

journal_title：Scientific reports

authors： Hu R,Chen J,Lujan B,Lei R,Zhang M,Wang Z,Liao M,Li Z,Wan Y,Liu F,Feng H,Wan Q

更新日期：2016-10-03 00:00:00

abstract：:The aims of this study were, firstly, to assess the effect of concurrent peripheral artery disease (PAD) on the health-related quality of life (QOL) of people diagnosed with a small abdominal aortic aneurysm (AAA); and secondly, to test whether the peroxisome proliferator-activated receptor α agonist fenofibrate impro...

journal_title：Scientific reports

authors： Golledge J,Pinchbeck J,Rowbotham SE,Yip L,Jenkins JS,Quigley F,Moxon JV

更新日期：2020-09-03 00:00:00

abstract：:Voltage-gated sodium channels (VGSCs) play a vital role in controlling neuronal excitability. Nav1.6 is the most abundantly expressed VGSCs subtype in the adult central nervous system and has been found to contribute to facilitate the hyperexcitability of neurons after electrical induction of status epilepticus (SE). ...

journal_title：Scientific reports

authors： Zhu H,Zhao Y,Wu H,Jiang N,Wang Z,Lin W,Jin J,Ji Y

更新日期：2016-12-01 00:00:00

abstract：:Spinal Muscular Atrophy (SMA) is a monogenic neurodegenerative disorder and the leading genetic cause of infantile mortality. While several functions have been ascribed to the SMN (survival motor neuron) protein, their specific contribution to the disease has yet to be fully elucidated. We hypothesized that some, but ...

journal_title：Scientific reports

authors： Osman EY,Bolding MR,Villalón E,Kaifer KA,Lorson ZC,Tisdale S,Hao Y,Conant GC,Pires JC,Pellizzoni L,Lorson CL

更新日期：2019-07-01 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Fossum KN,Ovadnevaite J,Ceburnis D,Dall'Osto M,Marullo S,Bellacicco M,Simó R,Liu D,Flynn M,Zuend A,O'Dowd C

更新日期：2019-07-18 00:00:00

abstract：:We investigated the incidence, perioperative risk factors, and outcomes of postoperative acute kidney injury (AKI) in neurosurgical critically ill patients. A prospective multicenter cohort study was conducted, enrolling adult patients who underwent neurosurgical procedure and admitted to the neurosurgical intensive c...

journal_title：Scientific reports

authors： Deng Y,Yuan J,Chi R,Ye H,Zhou D,Wang S,Mai C,Nie Z,Wang L,Zhai Y,Gao L,Zhang D,Hu L,Deng Y,Chen C

更新日期：2017-06-26 00:00:00

abstract：:Understanding drought-tolerance mechanisms and identifying genetic dominance are important for crop improvement. Setaria italica, which is extremely drought-tolerant, has been regarded as a model plant for studying stress biology. Moreover, different genotypes of S. italica have evolved various drought-tolerance/avoid...

journal_title：Scientific reports

authors： Tang S,Li L,Wang Y,Chen Q,Zhang W,Jia G,Zhi H,Zhao B,Diao X

更新日期：2017-08-30 00:00:00

abstract：:Using two different hydrosilylation methods, low temperature thermal and UV initiation, silicon (111) hydrogenated surfaces were functionalized in presence of an OH-terminated alkyne, a CF3-terminated alkyne and a mixed equimolar ratio of the two alkynes. XPS studies revealed that in the absence of premeditated surfac...

journal_title：Scientific reports

authors： Khung YL,Ngalim SH,Scaccabarozi A,Narducci D

更新日期：2015-06-12 00:00:00

abstract：:Often ignored and regarded as mere transcriptional noise, long noncoding RNAs (lncRNAs) are starting to be considered key regulators of gene expression across the Eukarya domain of life. In the model diatom Phaeodactylum tricornutum, we have previously reported the occurrence of 1,510 intergenic lncRNAs (lincRNAs), ma...

journal_title：Scientific reports

authors： Cruz de Carvalho MH,Bowler C

更新日期：2020-08-24 00:00:00

abstract：:Current image processing methods for dynamic susceptibility contrast (DSC) magnetic resonance imaging (MRI) do not capture complex dynamic information of time-signal intensity curves. We investigated whether an autoencoder-based pattern analysis of DSC MRI captured representative temporal features that improves tissue...

journal_title：Scientific reports

authors： Park JE,Kim HS,Lee J,Cheong EN,Shin I,Ahn SS,Shim WH

更新日期：2020-12-08 00:00:00

abstract：:High content of organic matter in the downstream of watersheds underscored the severity of non-point source (NPS) pollution. The major objectives of this study were to characterize and quantify dissolved organic matter (DOM) in watersheds affected by NPS pollution, and to apply self-organizing map (SOM) and parallel f...

journal_title：Scientific reports

authors： Zhang Y,Liang X,Wang Z,Xu L

更新日期：2015-11-03 00:00:00

abstract：:The growth of epitaxial Si nanowires by a metal-catalyst-free process has been investigated as an alternative to the more common metal-catalyzed vapor-liquid-solid process. The well-aligned Si nanowires are successfully grown on a (111)-oriented Si substrate without any metal catalysts by a thermal treatment using sil...

journal_title：Scientific reports

authors： Ishiyama T,Nakagawa S,Wakamatsu T

更新日期：2016-07-28 00:00:00

abstract：:The continuous search for natural products that attenuate age-related losses has increasingly gained notice; among them, those applicable for skin care have drawn significant attention. The bioester generated from the Chenopodium quinoa's oil is a natural-origin ingredient described to produce replenishing skin effect...

journal_title：Scientific reports

authors： Camillo-Andrade AC,Santos MDM,Fischer JSG,Swinka BB,Bosquetti B,Schuck DC,Pincerati MR,Lorencini M,Carvalho PC

更新日期：2020-11-10 00:00:00

abstract：:Hypertension and diabetes mellitus (DM) have become major public health issues, and previous studies have shown that there is an association between hypertension and DM. However, there is a lack of detailed information about this association. This study aimed to explore how different blood pressure (BP) levels were as...

journal_title：Scientific reports

authors： Lv Y,Yao Y,Ye J,Guo X,Dou J,Shen L,Zhang A,Xue Z,Yu Y,Jin L

更新日期：2018-05-21 00:00:00

abstract：:Most Atlantic hurricanes form in the Main Development Region between 9°N to 20°N along the northern edge of the Intertropical Convergence Zone (ITCZ). Previous research has suggested that meridional shifts in the ITCZ position on geologic timescales can modulate hurricane activity, but continuous and long-term storm r...

journal_title：Scientific reports

authors： van Hengstum PJ,Donnelly JP,Fall PL,Toomey MR,Albury NA,Kakuk B

更新日期：2016-02-24 00:00:00

abstract：:Cytochrome P450 (CYP) 3A accounts for nearly 30% of the total CYP enzymes in the human liver and participates in the metabolism of over 50% of clinical drugs. Moreover, CYP3A plays an important role in chemical metabolism, toxicity, and carcinogenicity. New animal models are needed to investigate CYP3A functions, espe...

journal_title：Scientific reports

authors： Lu J,Shao Y,Qin X,Liu D,Chen A,Li D,Liu M,Wang X

更新日期：2017-02-20 00:00:00

abstract：:The ubiquitin-proteasomal degradation mechanism has gained the attention over the past decade. The E2 ubiquitin conjugating enzymes are the crucial part of ubiquitination mechanism and they are believed to hold imperative association for plant development. It accepts ubiquitin from the E1 enzyme and interacts with the...

journal_title：Scientific reports

authors： Sharma B,Bhatt TK

更新日期：2017-08-17 00:00:00