Key role of 15-LO/15-HETE in angiogenesis and functional recovery in later stages of post-stroke mice.

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Ágg B,Baranyai T,Makkos A,Vető B,Faragó N,Zvara Á,Giricz Z,Veres DV,Csermely P,Arányi T,Puskás LG,Varga ZV,Ferdinandy P

更新日期：2018-08-09 00:00:00

abstract：:Recent stroke studies have shown that the ipsi-lesional thalamus longitudinally and significantly decreases after stroke in the acute and subacute stages. However, additional considerations in the chronic stages of stroke require exploration including time since stroke, gender, intracortical volume, aging, and lesion ...

journal_title：Scientific reports

authors： Krishnamurthy LC,Champion GN,McGregor KM,Krishnamurthy V,Turabi A,Roberts SR,Nocera JR,Borich MR,Rodriguez AD,Belagaje SR,Harrington RM,Harris-Love ML,Harnish SM,Drucker JH,Benjamin M,Meadows ML,Seeds L,Zlatar ZZ,Sudh

更新日期：2020-11-24 00:00:00

abstract：:Group A Streptococcus (GAS) secretes deoxyribonucleases and evades neutrophil extracellular killing by degrading neutrophil extracellular traps (NETs). However, limited information is currently available on the interaction between GAS and NETs in the pathogenicity of GAS pharyngitis. In this study, we modified a mouse...

journal_title：Scientific reports

authors： Tanaka M,Kinoshita-Daitoku R,Kiga K,Sanada T,Zhu B,Okano T,Aikawa C,Iida T,Ogura Y,Hayashi T,Okubo K,Kurosawa M,Hirahashi J,Suzuki T,Nakagawa I,Nangaku M,Mimuro H

更新日期：2020-02-24 00:00:00

abstract：:RNA interference (RNAi) is being developed for the management of pests that destroy crops. The twospotted Spider Mite (TSSM), Tetranychus urticae is a worldwide pest due to its unique physiological and behavioral characteristics including extraordinary ability to detoxify a wide range of pesticides and feed on many ho...

journal_title：Scientific reports

authors： Yoon JS,Sahoo DK,Maiti IB,Palli SR

更新日期：2018-10-02 00:00:00

abstract：:Beneficial effects of CO2 on photosynthetic organisms will be a key driver of ecosystem change under ocean acidification. Predicting the responses of macroalgal species to ocean acidification is complex, but we demonstrate that the response of assemblages to elevated CO2 are correlated with inorganic carbon physiology...

journal_title：Scientific reports

authors： Cornwall CE,Revill AT,Hall-Spencer JM,Milazzo M,Raven JA,Hurd CL

更新日期：2017-04-18 00:00:00

abstract：:Continuous, as opposed to pulsatile, delivery of hypothalamic gonadotropin-releasing hormone (GnRH) leads to a marked decrease in secretion of pituitary gonadotropins LH and FSH and impairment of reproductive function. Here we studied the expression profile of gonadotropin subunit and GnRH receptor genes in rat pituit...

journal_title：Scientific reports

authors： Janjic MM,Prévide RM,Fletcher PA,Sherman A,Smiljanic K,Abebe D,Bjelobaba I,Stojilkovic SS

更新日期：2019-12-27 00:00:00

abstract：:Hyperactivated mTOR signaling in the developing brain has been implicated in multiple forms of pathology including tuberous sclerosis complex (TSC). To date, various phenotypic defects such as cortical lamination irregularity, subependymal nodule formation, dysmorphic astrocyte differentiation and dendritic malformati...

journal_title：Scientific reports

authors： Shin J,Kim M,Jung HJ,Cha HL,Suh-Kim H,Ahn S,Jung J,Kim Y,Jun Y,Lee S,Hwang D,Kim J

更新日期：2017-06-06 00:00:00

abstract：:Escherichia coli and Salmonella Enteritidis are foodborne pathogens forming challenging biofilms that contribute to their virulence, antimicrobial resistance, and survival on surfaces. Interspecies interactions occur between species in mixed biofilms promoting different outcomes to each species. Here we describe the i...

journal_title：Scientific reports

authors： Milho C,Silva MD,Alves D,Oliveira H,Sousa C,Pastrana LM,Azeredo J,Sillankorva S

更新日期：2019-12-03 00:00:00

abstract：:The performance of most error-correction (EC) algorithms that operate on genomics reads is dependent on the proper choice of its configuration parameters, such as the value of k in k-mer based techniques. In this work, we target the problem of finding the best values of these configuration parameters to optimize error...

journal_title：Scientific reports

authors： Abdallah M,Mahgoub A,Ahmed H,Chaterji S

更新日期：2019-11-06 00:00:00

abstract：:Increased evidence suggests that dysregulation of cholesterol metabolism may be a key event contributing to progression of multiple sclerosis (MS). Using an experimental autoimmune encephalomyelitis (EAE) model of MS we revealed specific changes in the mRNA and protein expression of key molecules involved in the maint...

journal_title：Scientific reports

authors： Lavrnja I,Smiljanic K,Savic D,Mladenovic-Djordjevic A,Tesovic K,Kanazir S,Pekovic S

更新日期：2017-06-02 00:00:00

abstract：:Frequency shifts in signals of bats flying near conspecifics have been interpreted as a spectral jamming avoidance response (JAR). However, several prerequisites supporting a JAR hypothesis have not been controlled for in previous studies. We recorded flight and echolocation behavior of foraging Pipistrellus pipistrel...

journal_title：Scientific reports

authors： Götze S,Koblitz JC,Denzinger A,Schnitzler HU

更新日期：2016-08-09 00:00:00

abstract：:Protein synthesis is traditionally associated with specific cytoplasmic compartments. We now show that OFD1, a centrosomal/basal body protein, interacts with components of the Preinitiation complex of translation (PIC) and of the eukaryotic Initiation Factor (eIF)4F complex and modulates the translation of specific mR...

journal_title：Scientific reports

authors： Iaconis D,Monti M,Renda M,van Koppen A,Tammaro R,Chiaravalli M,Cozzolino F,Pignata P,Crina C,Pucci P,Boletta A,Belcastro V,Giles RH,Surace EM,Gallo S,Pende M,Franco B

更新日期：2017-04-27 00:00:00

abstract：:The cardiac neural crest cells (cNCCs) and the second heart field (SHF) play key roles in development of the cardiac outflow tract (OFT) for establishment of completely separated pulmonary and systemic circulations in vertebrates. A neurovascular guiding factor, Semaphorin 3c (Sema3c), is required for the development ...

journal_title：Scientific reports

authors： Kodo K,Shibata S,Miyagawa-Tomita S,Ong SG,Takahashi H,Kume T,Okano H,Matsuoka R,Yamagishi H

更新日期：2017-07-28 00:00:00

abstract：:Sentinel lymph node (SLN) mapping using dye or radioisotopes has been performed in patients with uterine cancer. Superparamagnetic iron oxide (SPIO) can be handled safely and is taken up by lymph nodes (LNs); however, its efficacy in detecting SLNs in uterine cancer remains unknown. This pilot study evaluated the use ...

journal_title：Scientific reports

authors： Murakami K,Kotani Y,Suzuki A,Takaya H,Nakai H,Matsuki M,Sato T,Mandai M,Matsumura N

更新日期：2020-05-14 00:00:00

abstract：:The applications of spin dynamos, which could potentially power complex nanoscopic devices, have so far been limited owing to their extremely low energy conversion efficiencies. Here, we present a unique plasmonic diabolo cavity (PDC) that dramatically improves the spin rectification signal (enhancement of more than t...

journal_title：Scientific reports

authors： Gou P,Qian J,Xi F,Zou Y,Cao J,Yu H,Zhao Z,Yang L,Xu J,Wang H,Zhang L,An Z

更新日期：2017-07-13 00:00:00

abstract：:A soil remediation method based on magnetic beneficiation is reported. A new magnetic solid chelator powder, FS@IDA (core-shell Fe3O4@SiO2 nanoparticles coated with iminodiacetic acid chelators), was used as a reactive magnetic carrier to selectively capture non-magnetic heavy metals in soil by chelation and removal b...

journal_title：Scientific reports

authors： Fan L,Song J,Bai W,Wang S,Zeng M,Li X,Zhou Y,Li H,Lu H

更新日期：2016-02-16 00:00:00

abstract：:Hot days in summer (involving a few hours at particularly high temperatures) are expected to become more common under climate change. How such events at different life stages affect survival and reproduction remains unclear in most organisms. Here, we investigated how an exposure to 40 °C at different life stages in t...

journal_title：Scientific reports

authors： Zhang W,Chang XQ,Hoffmann A,Zhang S,Ma CS

更新日期：2015-05-22 00:00:00

abstract：:High-throughput single-stranded DNA sequencing (ssDNA-seq) of cell-free DNA from plasma and other bodily fluids is a powerful method for non-invasive prenatal testing, and diagnosis of cancers and other diseases. Here, we developed a facile ssDNA-seq method, which exploits a novel template-switching activity of thermo...

journal_title：Scientific reports

authors： Wu DC,Lambowitz AM

更新日期：2017-08-21 00:00:00

abstract：:Hand, foot and mouth disease (HFMD) is a substantial burden throughout Asia, but the effects of temperature pattern on HFMD risk are inconsistent. To quantify the effect of temperature on HFMD incidence, Wuhan was chosen as the study site because of its high temperature variability and high HFMD incidence. Daily serie...

journal_title：Scientific reports

authors： Huang J,Chen S,Wu Y,Tong Y,Wang L,Zhu M,Hu S,Guan X,Wei S

更新日期：2018-01-31 00:00:00

abstract：:Inflammation plays central roles in the immune response. Inflammatory response normally requires higher energy and therefore is associated with glucose metabolism. Our recent study demonstrates that lncRNA HOTAIR plays key roles in NF-kB activation, cytokine expression, and inflammation. Here, we investigated if HOTAI...

journal_title：Scientific reports

authors： Obaid M,Udden SMN,Alluri P,Mandal SS

更新日期：2021-01-08 00:00:00

abstract：:Carbon quantum dots (C-QDs) are becoming a desirable alternative to metal-based QDs and dye probes owing to their high biocompatibility, low toxicity, ease of preparation, and unique photophysical properties. Herein, we describe fluorescence bioimaging of zebrafish using C-QDs as probe in terms of the preparation of C...

journal_title：Scientific reports

authors： Kang YF,Li YH,Fang YW,Xu Y,Wei XM,Yin XB

更新日期：2015-07-02 00:00:00

abstract：:The combination of genome-edited human embryonic stem cells (hESCs) and subsequent neural differentiation is a powerful tool to study neurodevelopmental disorders. Since the naïve state of pluripotency has favourable characteristics for efficient genome-editing, we optimized a workflow for the CRISPR/Cas9 system in th...

journal_title：Scientific reports

authors： Jacobs EZ,Warrier S,Volders PJ,D'haene E,Van Lombergen E,Vantomme L,Van der Jeught M,Heindryckx B,Menten B,Vergult S

更新日期：2017-11-30 00:00:00

abstract：:Heat stress threatens agriculture worldwide. Plants acquire heat stress tolerance through priming, which establishes stress memory during mild or severe transient heat stress. Such induced thermotolerance restructures metabolic networks and helps maintain metabolic homeostasis under heat stress. Here, we used an elect...

journal_title：Scientific reports

authors： Serrano N,Ling Y,Bahieldin A,Mahfouz MM

更新日期：2019-01-17 00:00:00

abstract：:The transfer of the flexor hallucis longus tendon or flexor digitorum longus tendon is frequently used for the treatment of posterior tibial tendon insufficiency or chronic Achilles tendinopathy. According to several anatomical studies, harvesting the flexor hallucis longus (FHL) tendon may cause nerve injury. Sixty-e...

journal_title：Scientific reports

authors： Mao H,Dong W,Shi Z,Yin W,Xu D,Wapner KL

更新日期：2017-10-27 00:00:00

abstract：:Myocardial ischemia culminates in ATP production impairment, ionic derangement and cell death. The provision of metabolic substrates during reperfusion significantly increases heart tolerance to ischemia by improving mitochondrial performance. Under normoxia, glutamate contributes to myocardial energy balance as subst...

journal_title：Scientific reports

authors： Maiolino M,Castaldo P,Lariccia V,Piccirillo S,Amoroso S,Magi S

更新日期：2017-10-12 00:00:00

abstract：:This corrects the article DOI: 10.1038/srep42494. ...

journal_title：Scientific reports

authors： Bodra N,Young D,Rosado LA,Pallo A,Wahni K,De Proft F,Huang J,Van Breusegem F,Messens J

更新日期：2017-08-24 00:00:00

abstract：:Tumour tracking is an advanced radiotherapy technique for precise treatment of tumours subject to organ motion. In this work, we addressed crucial aspects of dose delivery for its realisation in pencil beam scanning proton therapy, exploring the momentum acceptance and global achromaticity of a Gantry beamline to perf...

journal_title：Scientific reports

authors： Fattori G,Zhang Y,Meer D,Weber DC,Lomax AJ,Safai S

更新日期：2020-09-18 00:00:00

abstract：:Nanoparticles are widely used in commodities, and pregnant women are inevitably exposed to these particles. The placenta protects the growing fetus from foreign or toxic materials, and provides energy and oxygen. Here we report that autophagy, a cellular mechanism to maintain homeostasis, engulfs platinum nanoparticle...

journal_title：Scientific reports

authors： Nakashima A,Higashisaka K,Kusabiraki T,Aoki A,Ushijima A,Ono Y,Tsuda S,Shima T,Yoshino O,Nagano K,Yoshioka Y,Tsutsumi Y,Saito S

更新日期：2019-04-02 00:00:00

abstract：:Working memory capacity is incredibly limited and thus it is important to use this resource wisely. Prior knowledge in long-term memory can aid in efficient encoding of information by allowing for the prioritization of novel stimuli over familiar ones. Here we used a full-report procedure in a visual working memory pa...

journal_title：Scientific reports

authors： Bruning AL,Lewis-Peacock JA

更新日期：2020-12-17 00:00:00

abstract：BACKGROUND:Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency leads to impaired cortisol biosynthesis. Treatment includes glucocorticoid supplementation. We studied the specific metabolomics signatures in CAH patients using two different algorithms. METHODS:In a case-control study of CAH patients ma...

journal_title：Scientific reports

authors： Nguyen LS,Prifti E,Ichou F,Leban M,Funck-Brentano C,Touraine P,Salem JE,Bachelot A

更新日期：2020-06-01 00:00:00