Abstract：
:Drug delivery using suitable polymeric devices has gathered momentum in the recent years due to their remarkable properties. The versatility of polymeric materials makes them reliable candidates for site targeted drug release. Among them biodegradable sutures has received considerable attention because they offer great promises in the realm of drug delivery. Sutures have been found to be an effective strategy for the delivery of antibacterial agents or anti-inflammatory drugs to the surgical site. Recent developments yielded sutures with improved mechanical properties, but designing sutures with all the desirable properties is still under investigation. This review is an attempt to analyze the recent developments pertaining to biologically active sutures emphasizing their potential as drug delivery vehicle.
journal_name
Int J Pharmjournal_title
International journal of pharmaceuticsauthors
Joseph B,George A,Gopi S,Kalarikkal N,Thomas Sdoi
10.1016/j.ijpharm.2017.03.041subject
Has Abstractpub_date
2017-05-30 00:00:00pages
454-466issue
1-2eissn
0378-5173issn
1873-3476pii
S0378-5173(17)30216-8journal_volume
524pub_type
杂志文章,评审abstract：:The conventional medications are still facing a huge challenge for the treatment of rheumatoid arthritis (RA). Thus, looking for an effective therapy of RA has became an urgent issue nowadays. In this study, a novel thermosensitive liposome loaded with sinomenine hydrochloride (SIN-TSL) was developed by a pH gradient ...
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