PCTK3/CDK18 regulates cell migration and adhesion by negatively modulating FAK activity.

abstract：:The aim of this study was to investigate the characteristics of insulin producing cells (IPCs) differentiated from adipose-tissue derived stem cells (ADSCs) isolated from human subcutaneous and visceral adipose tissues and identify ADSCs suitable for differentiation into efficient and functional IPCs. Subcutaneous and...

journal_title：Scientific reports

authors： Wada Y,Ikemoto T,Morine Y,Imura S,Saito Y,Yamada S,Shimada M

更新日期：2019-09-13 00:00:00

abstract：:The plasmonic waveguide made of uniform corrugated metallic strip can support and guide spoof surface plasmon polaritons (SSPPs) with high confinements. Here, we propose periodically-modulated plasmonic waveguide composed of non-uniform corrugated metallic strip to convert SSPPs to radiating waves, in which the main b...

journal_title：Scientific reports

authors： Kong GS,Ma HF,Cai BG,Cui TJ

更新日期：2016-07-12 00:00:00

abstract：:The Turin Shroud is traditionally considered to be the burial cloth in which the body of Jesus Christ was wrapped after his death approximately 2000 years ago. Here, we report the main findings from the analysis of genomic DNA extracted from dust particles vacuumed from parts of the body image and the lateral edge use...

journal_title：Scientific reports

authors： Barcaccia G,Galla G,Achilli A,Olivieri A,Torroni A

更新日期：2015-10-05 00:00:00

abstract：:Cervical oesophageal cancer (CEC) is a relatively uncommon malignancy. The biological behaviour and treatment have not been well studied. This retrospective study reviewed the clinicopathological features of 28 patients with CEC who underwent surgical resection to investigate the biological behaviour, treatment and pr...

journal_title：Scientific reports

authors： Chen SB,Yang XH,Weng HR,Liu DT,Li H,Chen YP

更新日期：2017-06-12 00:00:00

abstract：:Mycoplasma pneumoniae infection is conventionally diagnosed using serum antibody testing, microbial culture, and genetic testing. Recently, immunochromatography-based rapid mycoplasma antigen test kits have been developed and commercialised for rapid diagnosis of M. pneumoniae infection. However, as these kits do not ...

journal_title：Scientific reports

authors： Namkoong H,Yamazaki M,Ishizaki M,Endo I,Harada N,Aramaki M,Tanaka Y,Kaburagi S,Ichikawa M,Ohata T,Sakaguchi S,Saito F,Nakao A,Yuki H,Mitamura K

更新日期：2018-01-23 00:00:00

abstract：:The present work demonstrates the synthesis, characterization and biological activities of different concentrations of tin doped indium oxide nanoparticles (Sn doped In2O3 NPs), i.e., (Sn/In = 5%, 10% and 15%). We have synthesized different size (38.11 nm, 18.46 nm and 10.21 nm) of Sn doped In2O3 NPs. by using an ultr...

journal_title：Scientific reports

authors： Rehman S,Asiri SM,Khan FA,Jermy BR,Ravinayagam V,Alsalem Z,Jindan RA,Qurashi A

更新日期：2020-02-24 00:00:00

abstract：:The accurate staging of liver fibrosis is of paramount importance to determine the state of disease progression, therapy responses, and to optimize disease treatment strategies. Non-linear optical microscopy techniques such as two-photon excitation fluorescence (TPEF) and second harmonic generation (SHG) can image the...

journal_title：Scientific reports

authors： Stanciu SG,Xu S,Peng Q,Yan J,Stanciu GA,Welsch RE,So PT,Csucs G,Yu H

更新日期：2014-04-10 00:00:00

abstract：:Membrane type 1 metalloproteinase (MT1-MMP) is an important regulator of cancer invasion, growth and angiogenesis, thus making it an attractive target for cancer imaging and therapy. A non-substrate peptide (MT1-AF7p) that bonded to the "MT-Loop" region of MT1-MMP was identified by using a phage-displayed peptide libr...

journal_title：Scientific reports

authors： Ren L,Wang Y,Zhu L,Shen L,Zhang J,Wang J,Li H,Zheng Q,Yu D,Fang X

更新日期：2018-07-09 00:00:00

abstract：:Nuclear magnetic resonance (NMR) is a fundamental research tool that is widely used in many fields. Despite its powerful applications, unfortunately the low sensitivity of conventional NMR makes it difficult to study thin film or nano-sized samples. In this work, we report the first NMR spectrum obtained from general ...

journal_title：Scientific reports

authors： Won S,Saun SB,Lee S,Lee S,Kim K,Han Y

更新日期：2013-11-12 00:00:00

abstract：:Currently, exercise-based cardiac rehabilitation (CR) is the only recommended secondary prevention strategy for cardiac patients that attempts to tackle stress and psychosocial wellbeing, but it is under-utilized and lacks a comprehensive curriculum for this purpose; hence there is a critical gap to address psychosoci...

journal_title：Scientific reports

authors： Nijjar PS,Connett JE,Lindquist R,Brown R,Burt M,Pergolski A,Wolfe A,Balaji P,Chandiramani N,Yu X,Kreitzer MJ,Everson-Rose SA

更新日期：2019-12-05 00:00:00

abstract：:We summarized published data on the associations of apolipoprotein E (APOE) gene ε2/ε3/ε4 polymorphism with both cancer risk and circulating lipid profiles, aiming to examine the causal relevance between lipids and cancer risk. Article identification and data abstraction were conducted in duplicate and independently b...

journal_title：Scientific reports

authors： Yang C,Tian G,Mi J,Wei X,Li X,Li X,Wang W,Wang B

更新日期：2015-03-30 00:00:00

abstract：:This corrects the article DOI: 10.1038/srep25577. ...

journal_title：Scientific reports

authors： Veysset D,Hsieh AJ,Kooi S,Maznev AA,Masser KA,Nelson KA

更新日期：2018-02-16 00:00:00

abstract：:We have experimentally demonstrated a strong correlation between the electrical properties of Zn1-xTex Ovonic threshold switching (OTS) selector device and the material properties analysed by X-ray diffraction (XRD), spectroscopic ellipsometry, and X-ray photoelectron spectroscopy (XPS). The correlation and the key ma...

journal_title：Scientific reports

authors： Koo Y,Hwang H

更新日期：2018-08-07 00:00:00

abstract：:Immune-evasion and immune checkpoints are promising new therapeutic targets for several cancer entities. In ovarian cancer, the clinical role of programmed cell death receptor ligand 1 (PD-L1) expression as mechanism to escape immune recognition has not been clarified yet. We analyzed PD-L1 expression of primary ovari...

journal_title：Scientific reports

authors： Aust S,Felix S,Auer K,Bachmayr-Heyda A,Kenner L,Dekan S,Meier SM,Gerner C,Grimm C,Pils D

更新日期：2017-03-07 00:00:00

abstract：:Pluripotent cells can be subdivided into two distinct states, the naïve and the primed state, the latter being further advanced on the path of differentiation. There are substantial differences in the regulation of pluripotency between human and mouse, and in humans only stem cells that resemble the primed state in mo...

journal_title：Scientific reports

authors： Ernst M,Abu Dawud R,Kurtz A,Schotta G,Taher L,Fuellen G

更新日期：2015-01-21 00:00:00

abstract：:Theranostics is the emerging field of medicine that uniquely combines diagnostic techniques and active agents to diagnose and treat medical conditions simultaneously or sequentially. Finding a theranostic agent capable to cure the affected cells and being safe for the healthy ones is the key for successful treatment. ...

journal_title：Scientific reports

authors： Golubewa L,Timoshchenko I,Romanov O,Karpicz R,Kulahava T,Rutkauskas D,Shuba M,Dementjev A,Svirko Y,Kuzhir P

更新日期：2020-12-17 00:00:00

abstract：:Once assumed only to be a waste product of anaerobe glycolytic activity, lactate is now recognized as an energy source in skeletal muscles. While lactate metabolism has been extensively studied in vivo, underlying cellular processes are poorly described. This study aimed to examine lactate metabolism in cultured human...

journal_title：Scientific reports

authors： Lund J,Aas V,Tingstad RH,Van Hees A,Nikolić N

更新日期：2018-06-29 00:00:00

abstract：:Conventional disease animal models have limitations on the conformity to the actual clinical situation. Disease-syndrome combination (DS) modeling may provide a more efficient strategy for biomedicine research. Disease model and DS model of renal fibrosis in chronic kidney disease were established by ligating the left...

journal_title：Scientific reports

authors： Li S,Xu P,Han L,Mao W,Wang Y,Luo G,Yang N

更新日期：2017-08-18 00:00:00

abstract：:Zirconium compounds has been widely attention over the last decades due to its excellent physical and chemical properties. Zirconium nitride nanopowders were synthesized via a simple direct carbothermic nitridation process of internal gel derived zirconia in the presence of nano-sized carbon black. The effects of reac...

journal_title：Scientific reports

authors： Zhao S,Ma J,Xu R,Lin X,Cheng X,Hao S,Zhao X,Deng C,Liu B

更新日期：2019-12-16 00:00:00

abstract：:This paper reports the application of anthracite particles of different sizes and coated with nine kinds of layered double hydroxides (LDHs) varying in M(II)-M(III) cations, as alternative substrates in the simulated vertical-flow constructed wetland columns. Effects of LDHs-coating and particle size of modified anthr...

journal_title：Scientific reports

authors： Zhang X,Guo L,Wang Y,Ruan C

更新日期：2015-10-12 00:00:00

abstract：:Intrahepatic cholestasis represents a frequent manifestation of drug-induced liver injury; however, the mechanisms underlying such injuries are poorly understood. In this study of human HepaRG and primary hepatocytes, we found that bile canaliculi (BC) underwent spontaneous contractions, which are essential for bile a...

journal_title：Scientific reports

authors： Sharanek A,Burban A,Burbank M,Le Guevel R,Li R,Guillouzo A,Guguen-Guillouzo C

更新日期：2016-05-12 00:00:00

abstract：:Single-nucleotide polymorphisms (SNPs) in cytokine genes can affect gene expression and thereby modulate inflammation and carcinogenesis. However, the data on the association between SNPs in the interleukin 1 beta gene (IL1B) and colorectal cancer (CRC) are conflicting. We found an association between a 4-SNP haplotyp...

journal_title：Scientific reports

authors： Sanabria-Salas MC,Hernández-Suárez G,Umaña-Pérez A,Rawlik K,Tenesa A,Serrano-López ML,Sánchez de Gómez M,Rojas MP,Bravo LE,Albis R,Plata JL,Green H,Borgovan T,Li L,Majumdar S,Garai J,Lee E,Ashktorab H,Brim H,Li L,

更新日期：2017-02-03 00:00:00

abstract：:Scrapie is a lethal neurodegenerative disease of sheep and goats caused by the misfolding of the prion protein. Variants such as M142, D145, S146, H154, Q211, and K222 were experimentally found to increase resistance or extend scrapie incubation period in goats. We aimed to identify polymorphisms in the Afar and Arsi-...

journal_title：Scientific reports

authors： Teferedegn EY,Yaman Y,Ün C

更新日期：2020-04-24 00:00:00

abstract：:The charge transport properties of hybrid halide perovskites are investigated with a combination of density functional theory including van der Waals interaction and the Boltzmann theory for diffusive transport in the relaxation time approximation. We find the mobility of electrons to be in the range 5-10 cm(2)V(-1)s(...

journal_title：Scientific reports

authors： Motta C,El-Mellouhi F,Sanvito S

更新日期：2015-08-03 00:00:00

abstract：:Milk is a major food of global economic importance, and its consumption is regarded as a classic example of gene-culture evolution. Humans have exploited animal milk as a food resource for at least 8500 years, but the origins, spread, and scale of dairying remain poorly understood. Indirect lines of evidence, such as ...

journal_title：Scientific reports

authors： Warinner C,Hendy J,Speller C,Cappellini E,Fischer R,Trachsel C,Arneborg J,Lynnerup N,Craig OE,Swallow DM,Fotakis A,Christensen RJ,Olsen JV,Liebert A,Montalva N,Fiddyment S,Charlton S,Mackie M,Canci A,Bouwman A,Rüh

更新日期：2014-11-27 00:00:00

abstract：:Given that the biological processes governing the oncogenesis of pancreatic cancers could present useful therapeutic targets, there is a pressing need to molecularly distinguish between different clinically relevant pancreatic cancer subtypes. To address this challenge, we used targeted proteomics and other molecular ...

journal_title：Scientific reports

authors： Sinkala M,Mulder N,Martin D

更新日期：2020-01-27 00:00:00

abstract：:Hungarians who live in Central Europe today are one of the westernmost Uralic speakers. Despite of the proposed Volga-Ural/West Siberian roots of the Hungarian language, the present-day Hungarian gene pool is highly similar to that of the surrounding Indo-European speaking populations. However, a limited portion of sp...

journal_title：Scientific reports

authors： Post H,Németh E,Klima L,Flores R,Fehér T,Türk A,Székely G,Sahakyan H,Mondal M,Montinaro F,Karmin M,Saag L,Yunusbayev B,Khusnutdinova EK,Metspalu E,Villems R,Tambets K,Rootsi S

更新日期：2019-05-24 00:00:00

abstract：:Fungal endophytes isolated from mountain-cultivated ginseng (MCG, Panax ginseng Meyer) were explored for their diversity and biocontrol activity against ginseng pathogens (Alternaria panax, Botrytis cinerea, Cylindrocarpon destructans, Pythium sp. and Rhizoctonia solani). A total of 1,300 isolates were isolated from t...

journal_title：Scientific reports

authors： Park YH,Kim Y,Mishra RC,Bae H

更新日期：2017-11-24 00:00:00

abstract：:Mycoplasma pneumoniae (MP) is considered a common cause of pneumonia, causing about 15-20% of adult community-acquired pneumonia (CAP) and up to 40% of cases in children. It has often been observed that MP epidemics last approximately 1-2 years and occur every 3-7 years, with the dominant strains alternating between e...

journal_title：Scientific reports

authors： Zhang XS,Zhao H,Vynnycky E,Chalker V

更新日期：2019-01-24 00:00:00

abstract：:Recently, structural colour formation and light control by accumulated guanine crystals were reported. However, the relationship between light interference by guanine platelets and light intensity in an individual platelet must be examined further. This study presents experimental evidence that the guanine crystal pla...

journal_title：Scientific reports

authors： Iwasaka M,Asada H

更新日期：2018-11-19 00:00:00