Positively interacting strains that co-circulate within a network structured population induce cycling epidemics of Mycoplasma pneumoniae.

abstract：:(R-)miniCHOP therapy, which delivers approximately half-doses of the (R-)CHOP regimen, has shown efficacy and safety in patients who are more than 80 years old. This study aimed to compare the area under the plasma concentration-time curves (AUCs) of vincristine (VCR), doxorubicin (DXR), and cyclophosphamide (CPA) bet...

journal_title：Scientific reports

authors： Nakagawa J,Takahata T,Hyodo R,Chen Y,Hasui K,Sasaki K,Saito K,Ueno K,Hosoi K,Terui K,Sato A,Niioka T

更新日期：2021-01-12 00:00:00

abstract：:A tetrameric N-acetyl galactosaminyl (GalNAc) peptidomimetic was constructed by N-acetylation of repeating proline-based hydroxamic acid units, followed by a convergent 'click chemistry' coupling. This novel glycopeptidomimetic was determined to effectively antagonize the interaction between a transmembrane hepatic le...

journal_title：Scientific reports

authors： Zhang HL,Zang Y,Xie J,Li J,Chen GR,He XP,Tian H

更新日期：2014-07-01 00:00:00

abstract：:Previous studies on the associations between dietary antioxidant vitamins and the risk of cervical cancer remain inconsistent, and little evidence is available for serum antioxidant vitamins, which provide more accurate measurements of these nutrients. We conducted a case-control study of 458 incident cases with invas...

journal_title：Scientific reports

authors： Guo L,Zhu H,Lin C,Che J,Tian X,Han S,Zhao H,Zhu Y,Mao D

更新日期：2015-09-04 00:00:00

abstract：:Novel pain killers without adverse effects are urgently needed. Opioids induce central and intestinal side effects such as respiratory depression, sedation, addiction, and constipation. We have recently shown that a newly designed agonist with a reduced acid dissociation constant (pKa) abolished pain by selectively ac...

journal_title：Scientific reports

authors： Spahn V,Del Vecchio G,Rodriguez-Gaztelumendi A,Temp J,Labuz D,Kloner M,Reidelbach M,Machelska H,Weber M,Stein C

更新日期：2018-06-12 00:00:00

abstract：:Specialized processing in the brain is performed by multiple groups of brain regions organized as functional modules. Although, in vivo studies of brain functional modules involve multiple functional Magnetic Resonance Imaging (fMRI) scans, the methods used to derive functional modules from functional networks of the ...

journal_title：Scientific reports

authors： Gupta S,Rajapakse JC

更新日期：2020-05-05 00:00:00

abstract：:Non-compressible hemorrhage is the most common preventable cause of death on battlefield and in civilian traumatic injuries. We report the use of microsecond pulses of electric current to induce rapid constriction in femoral and mesenteric arteries and veins in rats. Electrically-induced vasoconstriction could be indu...

journal_title：Scientific reports

authors： Mandel Y,Manivanh R,Dalal R,Huie P,Wang J,Brinton M,Palanker D

更新日期：2013-01-01 00:00:00

abstract：:This study investigates physicochemical impact of ultrasonic irradiations on surface topography of woven fabrics. In a simultaneous in-situ sonochemical method, the synthesis and coating of zinc oxide nanoparticles (ZnO NPs) on woven textiles were successfully achieved. Different instruments i.e. Alambeta, moisture ma...

journal_title：Scientific reports

authors： Noman MT,Petru M,Amor N,Louda P

更新日期：2020-12-03 00:00:00

abstract：:Shikimate is a key intermediate in the synthesis of neuraminidase inhibitors. Compared with traditional methods, microbial production of shikimate has the advantages of environmental friendliness, low cost, feed stock renewability, and product selectivity and diversity. Despite these advantages, shikimate kinase I and...

journal_title：Scientific reports

authors： Gu P,Su T,Wang Q,Liang Q,Qi Q

更新日期：2016-07-13 00:00:00

abstract：:Drought is one of the major impediments in wheat productivity. Traditional breeding and marker assisted QTL introgression had limited success. Available wheat genomic and RNA-seq data can decipher novel drought tolerance mechanisms with putative candidate gene and marker discovery. Drought is first sensed by root tiss...

journal_title：Scientific reports

authors： Iquebal MA,Sharma P,Jasrotia RS,Jaiswal S,Kaur A,Saroha M,Angadi UB,Sheoran S,Singh R,Singh GP,Rai A,Tiwari R,Kumar D

更新日期：2019-09-26 00:00:00

abstract：:Highly coordinated and coincidental patterns of activity-dependent mechanisms ("fire together wire together") are thought to serve as inductive signals during synaptogenesis, enabling neuronal pairing between specific sub-sets of excitatory partners. However, neither the nature of activity triggers, nor the "activity ...

journal_title：Scientific reports

authors： Luk CC,Lee AJ,Wijdenes P,Zaidi W,Leung A,Wong NY,Andrews J,Syed NI

更新日期：2015-04-01 00:00:00

abstract：:Abiotic emergence of ordered information stored in the form of RNA is an important unresolved problem concerning the origin of life. A polymer longer than 40-100 nucleotides is necessary to expect a self-replicating activity, but the formation of such a long polymer having a correct nucleotide sequence by random react...

journal_title：Scientific reports

authors： Totani T

更新日期：2020-02-03 00:00:00

abstract：:Caffeine modifies vascular/cardiac contractility. Embryonic exposure to caffeine altered cardiac functions in offspring. This study determined chronic influence of prenatal caffeine on vessel functions in offspring. Pregnant Sprague-Dawley rats (5-month-old) were exposed to high dose of caffeine, their offspring (5-mo...

journal_title：Scientific reports

authors： Li N,Li Y,Gao Q,Li D,Tang J,Sun M,Zhang P,Liu B,Mao C,Xu Z

更新日期：2015-08-17 00:00:00

abstract：:The barnase-barstar complex is one of the most stable protein-protein complexes and has a very wide range of possible applications. Here we report the use of top-down mass spectrometry for the investigation of the structure of this complex, its ionization via ESI, isolation and fragmentation. It was found that the asy...

journal_title：Scientific reports

authors： Kostyukevich Y,Shulga AA,Kononikhin A,Popov I,Nikolaev E,Deyev S

更新日期：2017-07-21 00:00:00

abstract：:In general, the poultry industry uses 0.5-1 ppm chlorine solution in the meat sanitization process. However, chlorine can react with organic material and produce halogenated organic compounds, notably chloroform, which causes bladder and rectal cancer in humans. For this reason, many industries try to avoid chlorine. ...

journal_title：Scientific reports

authors： Royintarat T,Choi EH,Boonyawan D,Seesuriyachan P,Wattanutchariya W

更新日期：2020-01-31 00:00:00

abstract：:Nacre, the gold standard for biomimicry, provides an excellent example and guideline for assembling high-performance composites. Inspired by the layered structure and extraordinary strength and toughness of natural nacre, nacre-like nanolignocellulose/poly (vinyl alcohol)/TiO2 composites possessed the similar layered ...

journal_title：Scientific reports

authors： Chen Y,Wang H,Dang B,Xiong Y,Yao Q,Wang C,Sun Q,Jin C

更新日期：2017-05-12 00:00:00

abstract：:A toolbox for the quantum simulation of polarons in ultracold atoms is presented. Motivated by the impressive experimental advances in the area of ultracold atomic mixtures, we theoretically study the problem of ultracold atomic impurities immersed in a Bose-Einstein condensate mixture (BEC). The coupling between impu...

journal_title：Scientific reports

authors： Compagno E,De Chiara G,Angelakis DG,Palma GM

更新日期：2017-05-24 00:00:00

abstract：:Exhaled nitric oxide (eNO) is a useful biomarker of various physiological conditions, including asthma and other pulmonary diseases. Herein a fast and sensitive analytical method has been developed for the quantitative detection of eNO based on extractive electrospray ionization mass spectrometry (EESI-MS). Exhaled NO...

journal_title：Scientific reports

authors： Pan S,Tian Y,Li M,Zhao J,Zhu L,Zhang W,Gu H,Wang H,Shi J,Fang X,Li P,Chen H

更新日期：2015-03-04 00:00:00

abstract：:We propose a hybrid sequential prediction model called "Deep Sequence", integrating radiomics-engineered imaging features, demographic, and visual factors, with a recursive neural network (RNN) model in the same platform to predict the risk of exudation within a future time-frame in non-exudative AMD eyes. The propose...

journal_title：Scientific reports

authors： Banerjee I,de Sisternes L,Hallak JA,Leng T,Osborne A,Rosenfeld PJ,Gregori G,Durbin M,Rubin D

更新日期：2020-09-22 00:00:00

abstract：:RFeO3 orthoferrites, where R is a rare-earth ion of the lanthanide series, are attracting attention mostly because of their promising fast spin dynamics. The magnetic properties of these materials seem to crucially depend on whether the magnetizations of the R and Fe ions' weak ferromagnetic (WFM) components are paral...

journal_title：Scientific reports

authors： Cao S,Chen L,Zhao W,Xu K,Wang G,Yang Y,Kang B,Zhao H,Chen P,Stroppa A,Zheng RK,Zhang J,Ren W,Íñiguez J,Bellaiche L

更新日期：2016-11-25 00:00:00

abstract：:Pot experiments were carried out to study the effects of rice straw (RS) and rice straw ash (RSA) on the growth of early rice and α-diversity of bacterial community in soils around rare earth mining areas of Xunwu and Xinfeng counties in South Jiangxi of China. The results showed that the exploitation of rare earth re...

journal_title：Scientific reports

authors： Jin S,Jin W,Dong C,Bai Y,Jin D,Hu Z,Huang Y

更新日期：2020-06-25 00:00:00

abstract：:The aim was to investigate the ability of self-assembling Peptide P11-4 Matrix (SAPM) to remineralize artificial initial caries lesions compared to the use of fluoride varnish. Volunteers were recruited for this randomised, cross-over in situ trial. Bovine specimens, half including orthodontic brackets, were recessed ...

journal_title：Scientific reports

authors： Jablonski-Momeni A,Korbmacher-Steiner H,Heinzel-Gutenbrunner M,Jablonski B,Jaquet W,Bottenberg P

更新日期：2019-01-22 00:00:00

abstract：:We have previously shown that OX40L/OX40 interaction is critical for TCR-independent selective proliferation of Foxp3+ Tregs, but not Foxp3- effector T-cells (Teff), when CD4+ T-cells are co-cultured with GM-CSF derived bone marrow dendritic cells (G-BMDCs). Events downstream of OX40L/OX40 interaction in Tregs respons...

journal_title：Scientific reports

authors： Alharshawi K,Marinelarena A,Kumar P,El-Sayed O,Bhattacharya P,Sun Z,Epstein AL,Maker AV,Prabhakar BS

更新日期：2017-07-26 00:00:00

abstract：:The South Asian subcontinent is characterized by a complex history of human migrations and population interactions. In this study, we used genome-wide data to provide novel insights on the demographic history and population relationships of six Indo-European populations from the Indian State of West Maharashtra. The s...

journal_title：Scientific reports

authors： Debortoli G,Abbatangelo C,Ceballos F,Fortes-Lima C,Norton HL,Ozarkar S,Parra EJ,Jonnalagadda M

更新日期：2020-06-22 00:00:00

abstract：:The ultrathin SmCo5 nanoflakes with average thickness smaller than 50 nm are prepared by a novel method of solid particle (NaCl) and surfactant co-assisted ball milling. The as-prepared nanoflakes exhibit a narrower thickness distribution of 10-50 nm and high coercivity of 23 kOe. The possible formation mechanism of n...

journal_title：Scientific reports

authors： Zuo WL,Zhao X,Zhao TY,Hu FX,Sun JR,Shen BG

更新日期：2016-05-13 00:00:00

abstract：:The quantum mechanical motion of electrons and nuclei in systems spatially confined to the molecular dimensions occurs on the sub-femtosecond to the femtosecond timescales respectively. Consequently, the study of ultrafast electronic and, in specific cases, nuclear dynamics requires the availability of light pulses wi...

journal_title：Scientific reports

authors： Makos I,Orfanos I,Nayak A,Peschel J,Major B,Liontos I,Skantzakis E,Papadakis N,Kalpouzos C,Dumergue M,Kühn S,Varju K,Johnsson P,L'Huillier A,Tzallas P,Charalambidis D

更新日期：2020-02-28 00:00:00

abstract：:A panel of 32 candidate reference genes was used to identify the most stable genes for gene normalisation in quantitative RT-PCR studies using endometrial biopsies obtained from women with endometrial cancer (type 1 or type 2) and without cancer (controls). RNA from the biopsies was isolated, examined for purity and q...

journal_title：Scientific reports

authors： Ayakannu T,Taylor AH,Konje JC

更新日期：2020-05-21 00:00:00

abstract：:Multidrug-resistant pathogens causing nosocomial and community acquired infections delineate a significant threat to public health. It had urged to identify new antimicrobials and thus, generated interest in studying macrocyclic metal complex, which has been studied in the past for their antimicrobial activity. Hence,...

journal_title：Scientific reports

authors： Brahma U,Kothari R,Sharma P,Bhandari V

更新日期：2018-05-23 00:00:00

abstract：:Ribosome biogenesis and turnover are processes necessary for cell viability and proliferation, and many kinds of proteins are known to regulate these processes. However, many questions still remain, especially in the Archaea. Generally, several ribonucleases are required to process precursor rRNAs to their mature form...

journal_title：Scientific reports

authors： Ikeda Y,Okada Y,Sato A,Kanai T,Tomita M,Atomi H,Kanai A

更新日期：2017-10-04 00:00:00

abstract：:Dinosaurs thrived and reproduced in various regions worldwide, including the Arctic. In order to understand their nesting in diverse or extreme environments, the relationships between nests, nesting environments, and incubation methods in extant archosaurs were investigated. Statistical analyses reveal that species of...

journal_title：Scientific reports

authors： Tanaka K,Zelenitsky DK,Therrien F,Kobayashi Y

更新日期：2018-03-15 00:00:00

abstract：:The establishment of clinically relevant models for tumor metastasis and drug testing is a major challenge in cancer research. Here we report a physiologically relevant assay enabling quantitative analysis of metastatic capacity of tumor cells following implantation into the chorioallantoic membrane (CAM). Engraftment...

journal_title：Scientific reports

authors： Pawlikowska P,Tayoun T,Oulhen M,Faugeroux V,Rouffiac V,Aberlenc A,Pommier AL,Honore A,Marty V,Bawa O,Lacroix L,Scoazec JY,Chauchereau A,Laplace-Builhe C,Farace F

更新日期：2020-10-09 00:00:00