Gene delivery to Nile tilapia cells for transgenesis and the role of PI3K-c2α in angiogenesis.

abstract：:Patients with scirrhous gastric cancer (SGC) frequently develop peritoneal dissemination, which leads to poor prognosis. The secreted protein angiopoietin-like-4 (ANGPTL4), which is induced by hypoxia, exerts diverse effects on cancer progression. Here, we aimed to determine the biological function of ANGPTL4 in SGC c...

journal_title：Scientific reports

authors： Baba K,Kitajima Y,Miyake S,Nakamura J,Wakiyama K,Sato H,Okuyama K,Kitagawa H,Tanaka T,Hiraki M,Yanagihara K,Noshiro H

更新日期：2017-09-11 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Weckmann K,Diefenthäler P,Baeken MW,Yusifli K,Turck CW,Asara JM,Behl C,Hajieva P

更新日期：2018-08-10 00:00:00

abstract：:Identification of loci or genes under natural selection is important for both understanding the genetic basis of local adaptation and practical applications, and genome scans provide a powerful means for such identification purposes. In this study, genome-wide simple sequence repeats markers (SSRs) were used to scan f...

journal_title：Scientific reports

authors： Song Z,Zhang M,Li F,Weng Q,Zhou C,Li M,Li J,Huang H,Mo X,Gan S

更新日期：2016-10-17 00:00:00

abstract：:This work presents the measurement of the permittivities of water and methanol in the D-band. Water is a reference medium for dielectric measurement. The dielectric permittivity of water in the millimeter wave range is a fundamental parameter in many applications, and needs to be investigated systematically. The measu...

journal_title：Scientific reports

authors： Liu X,Yu J

更新日期：2019-12-06 00:00:00

abstract：:Quality assessment of protein models using no other information than the structure of the model itself has been shown to be useful for structure prediction. Here, we introduce two novel methods, ProQRosFA and ProQRosCen, inspired by the state-of-art method ProQ2, but using a completely different description of a prote...

journal_title：Scientific reports

authors： Uziela K,Shu N,Wallner B,Elofsson A

更新日期：2016-10-04 00:00:00

abstract：:Selective serotonin reuptake inhibitors are among the most prescribed antidepressants. Fluoxetine is the lead molecule which exerts its therapeutic effects, at least in part, by promoting neuroplasticity through increased brain-derived neurotrophic factor (BDNF)/tropomyosin-related receptor kinase B (TrkB) signalling....

journal_title：Scientific reports

authors： Levy MJF,Boulle F,Emerit MB,Poilbout C,Steinbusch HWM,Van den Hove DLA,Kenis G,Lanfumey L

更新日期：2019-04-19 00:00:00

abstract：:Magnetite (Fe3O4) is an iron ore mineral that is globally mined especially for steel production. It is denser (5.15 g/cm3) than Earth's crust (~2.7 g/cm3) and is expected to accumulate at the bottom of melt-rich magma reservoirs. However, recent studies revealed heterogeneous fluid bubble nucleation on oxide minerals ...

journal_title：Scientific reports

authors： Knipping JL,Webster JD,Simon AC,Holtz F

更新日期：2019-03-07 00:00:00

abstract：:Fast volumetric microscopy is required to monitor large-scale neural ensembles with high spatio-temporal resolution. Widefield fluorescence microscopy can image large 2D fields of view at high resolution and speed while remaining simple and costeffective. A focal sweep add-on can further extend the capacity of widefie...

journal_title：Scientific reports

authors： Xiao S,Tseng HA,Gritton H,Han X,Mertz J

更新日期：2018-05-21 00:00:00

abstract：:Thyroid hormone (TH) has long been believed to play a minor role in male reproduction. However, evidences from experimental model of thyrotoxicosis or hypothyroidism suggests its role in spermatogenesis. Cellular action of TH requires membrane transport via specific transporters such as monocarboxylate transporter 8 (...

journal_title：Scientific reports

authors： Bae HS,Jin YK,Ham S,Kim HK,Shin H,Cho GB,Lee KJ,Lee H,Kim KM,Koo OJ,Jang G,Lee JM,Lee JY

更新日期：2020-07-07 00:00:00

abstract：:Malignant peripheral nerve sheath tumors (MPNST) are aggressive cancers that occur spontaneously (sporadic MPNST) or from benign plexiform neurofibromas in neurofibromatosis type 1 (NF1) patients. MPNSTs metastasize easily, are therapy resistant and are frequently fatal. The molecular changes underlying the malignant ...

journal_title：Scientific reports

authors： Amirnasr A,Verdijk RM,van Kuijk PF,Kartal P,Vriends ALM,French PJ,van Royen ME,Taal W,Sleijfer S,Wiemer EAC

更新日期：2020-02-19 00:00:00

abstract：:We report, for the first time, that the energy of femtosecond optical laser pulses, E, with relativistic intensities I > 10(21)  W/cm(2) is efficiently converted to X-ray radiation, which is emitted by "hot" electron component in collision-less processes and heats the solid density plasma periphery. As shown by direct...

journal_title：Scientific reports

authors： Faenov AY,Colgan J,Hansen SB,Zhidkov A,Pikuz TA,Nishiuchi M,Pikuz SA,Skobelev IY,Abdallah J,Sakaki H,Sagisaka A,Pirozhkov AS,Ogura K,Fukuda Y,Kanasaki M,Hasegawa N,Nishikino M,Kando M,Watanabe Y,Kawachi T,Masuda S

更新日期：2015-09-02 00:00:00

abstract：:Nutritional supplements may be important on cognition but the evidence is heterogeneous. This meta-analysis aimed (1) to determine whether nutritional supplements provided to pregnant women or young children could improve cognitive development of children in developing countries, and (2) to explore how supplementation...

journal_title：Scientific reports

authors： Ip P,Ho FKW,Rao N,Sun J,Young ME,Chow CB,Tso W,Hon KL

更新日期：2017-09-06 00:00:00

abstract：:The poor intracellular uptake and non-specific binding of anticancer drugs into cancer cells are the bottlenecks in cancer therapy. Nanocarrier platforms provide the opportunities to improve the drug efficacy. Here we show a carbon-based nanomaterial nanodiamond (ND) that carried paclitaxel (PTX), a microtubule inhibi...

journal_title：Scientific reports

authors： Lin YW,Raj EN,Liao WS,Lin J,Liu KK,Chen TH,Cheng HC,Wang CC,Li LY,Chen C,Chao JI

更新日期：2017-08-29 00:00:00

abstract：:The graphdiyne (GD), a carbon allotrope with a 2D structure comprising benzene rings and carbon-carbon triple bonds, can be synthesized through cross-coupling on the surface of copper foil. The key problem is in understanding the dependence of layers number and properties, however, the controlled growth of the layers ...

journal_title：Scientific reports

authors： Qian X,Liu H,Huang C,Chen S,Zhang L,Li Y,Wang J,Li Y

更新日期：2015-01-13 00:00:00

abstract：:RNA-binding proteins are key regulators of post-transcriptional processes such as alternative splicing and mRNA stabilization. Rbm24 acts as a regulator of alternative splicing in heart and skeletal muscle, and is essential for sarcomere assembly. Homozygous inactivation of Rbm24 in mice disrupts cardiac development a...

journal_title：Scientific reports

authors： de Groot NE,van den Hoogenhof MMG,Najafi A,van der Made I,van der Velden J,Beqqali A,Pinto YM,Creemers EE

更新日期：2020-05-06 00:00:00

abstract：:Kuding tea is implicated in alleviating metabolic disorders in traditional Chinese medicine. However, the role of Ilex latifolia Thunb (kuding tea), one of the large leaf kuding tea species, in the prevention of the development of obesity remains to be determined. We show here that 7-week-old male mice treated with an...

journal_title：Scientific reports

authors： Wu H,Chen YL,Yu Y,Zang J,Wu Y,He Z

更新日期：2017-11-07 00:00:00

abstract：:The unconventional myosin MYO18A that contains a PDZ domain is required for muscle integrity during zebrafish development. However, the mechanism by which it functions in myofibers is not clear. The presence of a PDZ domain suggests that MYO18A may interact with other partners to perform muscle-specific functions. Her...

journal_title：Scientific reports

authors： Cao JM,Cheng XN,Li SQ,Heller S,Xu ZG,Shi DL

更新日期：2016-11-08 00:00:00

abstract：:Aim of this retrospective analysis was to evaluate the survival times after percutaneous irreversible electroporation (IRE) in inoperable liver tumors not amenable to thermal ablation. 71 patients (14 females, 57 males, median age 63.5 ± 10.8 years) with 103 liver tumors were treated in 83 interventions using IRE (Nan...

journal_title：Scientific reports

authors： Niessen C,Thumann S,Beyer L,Pregler B,Kramer J,Lang S,Teufel A,Jung EM,Stroszczynski C,Wiggermann P

更新日期：2017-03-07 00:00:00

abstract：:Rabies is still a public health threat in China. Evaluating the exposure history, clinical characteristics, and post-exposure prophylaxis (PEP) of the cases could help in identifying approaches to reducing the number of these preventable deaths. We analysed data collected from 10,971 case-investigations conducted in C...

journal_title：Scientific reports

authors： Guo C,Li Y,Huai Y,Rao CY,Lai S,Mu D,Yin W,Yu H,Nie S

更新日期：2018-11-21 00:00:00

abstract：:Clinically isolated syndrome (CIS) is the earliest clinical episode in multiple sclerosis (MS). Low environmental exposure to UV radiation is implicated in risk of developing MS, and therefore, narrowband UVB phototherapy might delay progression to MS in people with CIS. Twenty individuals with CIS were recruited, and...

journal_title：Scientific reports

authors： Trend S,Jones AP,Cha L,Cooper MN,Geldenhuys S,Fabis-Pedrini MJ,Carroll WM,Cole JM,Booth DR,Lucas RM,French MA,Byrne SN,Kermode AG,Hart PH

更新日期：2019-05-28 00:00:00

abstract：:Studies on dsDNA bacteriophages have revealed that a DNA packaging complex assembles at a special vertex called the 'portal vertex' and consists of a portal, a DNA packaging ATPase and other components. AdV protein IVa2 is presumed to function as a DNA packaging ATPase. However, a protein that functions as a portal is...

journal_title：Scientific reports

authors： Ahi YS,Hassan AO,Vemula SV,Li K,Jiang W,Zhang GJ,Mittal SK

更新日期：2017-08-08 00:00:00

abstract：:Grassland degradation due to overgrazing is common in many areas of the world. This study analyzed the potential of the stable carbon isotope (δ(13)C) value as a structural microcosmic index to monitor processes of grassland degradation. The δ(13)C values of plant leaves, roots and soils in non-grazed (NG) and over-gr...

journal_title：Scientific reports

authors： Yao H,Wilkes A,Zhu G,Zhang H,Liu X,Dan Ding,Zhai X,Tang S,Chen Q,Zhang Y,Huang D,Wang C

更新日期：2016-08-16 00:00:00

abstract：:A new ether-based electrolyte to match lithium metal electrode is prepared by introducing 1, 4-dioxane as co-solvent into lithium bis(fluorosulfonyl)imide/1,2-dimethoxyethane solution. Under the synergetic effect of solvents and salt, this simple liquid electrolyte presents stable Li cycling with dendrite-free Li depo...

journal_title：Scientific reports

authors： Miao R,Yang J,Xu Z,Wang J,Nuli Y,Sun L

更新日期：2016-02-16 00:00:00

abstract：:The purposes of this study are to investigate the neural representation of a speech stimulus in the auditory system of individuals with normal hearing (NH) and those with hearing aids (HAs) and to explore the impact of noise reduction algorithms (NR) on auditory brainstem response to complex sounds (cABR). Twenty NH i...

journal_title：Scientific reports

authors： Seol HY,Park S,Ji YS,Hong SH,Moon IJ

更新日期：2020-07-01 00:00:00

abstract：:We report a three dimensional (3D) quantitative visualization of a mammalian mitochondrion by coherent x-ray diffractive imaging (CXDI) using synchrotron radiation. The internal structures of a mitochondrion from a mouse embryonic fibroblast cell line (NIH3T3) were visualized by tomographic imaging at approximately 60...

journal_title：Scientific reports

authors： Kim Y,Kim C,Kwon OY,Nam D,Kim SS,Park JH,Kim S,Gallagher-Jones M,Kohmura Y,Ishikawa T,Song C,Tae G,Noh DY

更新日期：2017-05-12 00:00:00

abstract：:Chimpanzees (Pan troglodytes), one of humankinds' closest living relatives, are known to hunt and consume the meat of various animal taxa. Although some researchers have presented indirect evidence that chimpanzees may also prey on tortoises, until now, direct observations of this behaviour did not exist. Here, we pro...

journal_title：Scientific reports

authors： Pika S,Klein H,Bunel S,Baas P,Théleste E,Deschner T

更新日期：2019-05-23 00:00:00

abstract：:Pyrosomes are tunicates in the phylum Chordata, which also contains vertebrates. Their gigantic blooms play important ecological and biogeochemical roles in oceans. Pyrosoma, meaning "fire-body", derives from their brilliant bioluminescence. The biochemistry of this light production is unknown, but has been hypothesiz...

journal_title：Scientific reports

authors： Tessler M,Gaffney JP,Oliveira AG,Guarnaccia A,Dobi KC,Gujarati NA,Galbraith M,Mirza JD,Sparks JS,Pieribone VA,Wood RJ,Gruber DF

更新日期：2020-10-20 00:00:00

abstract：:Drug resistance in Clostridioides difficile becomes a public health concern worldwide, especially as the hypervirulent strains show decreased susceptibility to the first-line antibiotics for C. difficile treatment. Therefore, the simultaneous discovery and development of new compounds to fight this pathogen are urgent...

journal_title：Scientific reports

authors： Phanchana M,Phetruen T,Harnvoravongchai P,Raksat P,Ounjai P,Chankhamhaengdecha S,Janvilisri T

更新日期：2020-04-16 00:00:00

abstract：:New Delhi metallo-β-lactamase (NDM) had been reported to be the predominant carbapenemase among Escherichia coli in Taiwan. However, studies focusing on the clonal background and epidemiology of plasmids carrying NDM genes were limited. Between 2016 and 2018, all clinical E. coli and Klebsiella pneumoniae isolates tha...

journal_title：Scientific reports

authors： Huang YS,Tsai WC,Li JJ,Chen PY,Wang JT,Chen YT,Chen FJ,Lauderdale TL,Chang SC

更新日期：2021-01-28 00:00:00

abstract：:Bio-functionalized nanoparticles with semiconducting/metallic core encapsulated in a bio- or bio-derived materials are promising for applications in biology and especially in cancer diagnostic and healing. In this report, we report a facile, single-step, first-time synthesis and in-situ functionalization strategy for ...

journal_title：Scientific reports

authors： Liao W,Yu Z,Lin Z,Lei Z,Ning Z,Regenstein JM,Yang J,Ren J

更新日期：2015-12-21 00:00:00