Deregulated microRNAs in neurofibromatosis type 1 derived malignant peripheral nerve sheath tumors.

abstract：:Semen fertilizing potential is dependent upon the morphological, functional and molecular attributes of sperm. Sperm microRNAs (miRNAs) were recently shown to hold promise regarding their association with different fertility phenotypes. However, their role in fertility regulation remains to be determined. We postulate...

journal_title：Scientific reports

authors： Alves MBR,de Arruda RP,De Bem THC,Florez-Rodriguez SA,Sá Filho MF,Belleannée C,Meirelles FV,da Silveira JC,Perecin F,Celeghini ECC

更新日期：2019-07-17 00:00:00

abstract：:Cellulose is the major component of cell wall materials. A 300 bp specific fragment from the cDNA fragment was chosen to insert into vector pFGC1008 at forward and reverse orientations to construct the recombinant RNAi vector. Knockdown of BoiCesA caused "dwarf" phenotype with smaller leaves and a loss of the content ...

journal_title：Scientific reports

authors： Li S,Zhang L,Wang Y,Xu F,Liu M,Lin P,Ren S,Ma R,Guo YD

更新日期：2017-02-07 00:00:00

abstract：:Mulching with organic materials is a management practice with long history for weed suppression, soil water conservation and erosion control. Its potential impact on crop pests is less well explored. Here we report its utility for reducing crop damage by the serious pest, sweetpotato weevil (Cylas formicarius). Labora...

journal_title：Scientific reports

authors： Rehman M,Liu J,Johnson AC,Dada TE,Gurr GM

更新日期：2019-10-16 00:00:00

abstract：:Stable electroluminescence from micro-pixelated light-emitting diode (μLED) occurs when electrons and holes are continuously injected from external electrodes. Different from the general recognition, in this work, μLED works in an operation mode, namely, non-electrical contact and non-carrier injection mode, and can b...

journal_title：Scientific reports

authors： Wang K,Liu Y,Wu C,Li D,Lv S,Zhang Y,Zhou X,Guo T

更新日期：2020-05-15 00:00:00

abstract：:We previously found that Homeobox containing 1 (HMBOX1) was required for bone mesenchymal stem cell (BMSC) and mouse embryonic stem cell (ESC) differentiation into vascular endothelial cells (VECs). However, the function of HMBOX1 in VECs is still unknown. In this study, we found that HMBOX1 was abundantly expressed i...

journal_title：Scientific reports

authors： Ma H,Su L,Yue H,Yin X,Zhao J,Zhang S,Kung H,Xu Z,Miao J

更新日期：2015-10-12 00:00:00

abstract：:A high throughput method for species identification and classification through chemometric processing of direct analysis in real time (DART) mass spectrometry-derived fingerprint signatures has been developed. The method entails introduction of samples to the open air space between the DART ion source and the mass spe...

journal_title：Scientific reports

authors： Musah RA,Espinoza EO,Cody RB,Lesiak AD,Christensen ED,Moore HE,Maleknia S,Drijfhout FP

更新日期：2015-07-09 00:00:00

abstract：:The propagation of Toxoplasma gondii is accomplished by repeated lytic cycles of parasite attachment to a host cell, invasion, replication within a parasitophorous vacuole, and egress from the cell. This lytic cycle is delicately regulated by calcium-dependent reversible phosphorylation of the molecular machinery that...

journal_title：Scientific reports

authors： Yang C,Broncel M,Dominicus C,Sampson E,Blakely WJ,Treeck M,Arrizabalaga G

更新日期：2019-04-11 00:00:00

abstract：:Capable of mediating efficient transfection and protein production without eliciting innate immune responses, chemically modified mRNA holds great potential to produce paracrine factors at a physiologically beneficial level, in a spatiotemporally controlled manner, and with low toxicity. Although highly promising in c...

journal_title：Scientific reports

authors： Sun N,Ning B,Hansson KM,Bruce AC,Seaman SA,Zhang C,Rikard M,DeRosa CA,Fraser CL,Wågberg M,Fritsche-Danielson R,Wikström J,Chien KR,Lundahl A,Hölttä M,Carlsson LG,Peirce SM,Hu S

更新日期：2018-11-30 00:00:00

abstract：:Cyclamen persicum (cyclamen) is a commercially valuable, winter-blooming perennial plant. We cloned two cyclamen orthologues of AGAMOUS (AG), CpAG1 and CpAG2, which are mainly expressed in the stamen and carpel, respectively. Cyclamen flowers have 5 petals, but expression of a chimeric repressor of CpAG1 (CpAG1-SRDX) ...

journal_title：Scientific reports

authors： Tanaka Y,Oshima Y,Yamamura T,Sugiyama M,Mitsuda N,Ohtsubo N,Ohme-Takagi M,Terakawa T

更新日期：2013-01-01 00:00:00

abstract：:Optical thermometry has been widely studied to achieve an inaccessible temperature measurement in submicron scale and it has been reported that the temperature sensitivity depends mainly on host types. In this work, we propose a new method to improve the optical temperature sensitivity of Yb3+-Er3+ co-doped CaWO4 phos...

journal_title：Scientific reports

authors： Wang X,Wang Y,Bu Y,Yan X,Wang J,Cai P,Vu T,Seo HJ

更新日期：2017-02-27 00:00:00

abstract：:Screening and in silico modeling are critical activities for the reduction of experimental costs. They also speed up research notably and strengthen the theoretical framework, thus allowing researchers to numerically quantify the importance of a particular subset of information. For example, in fields such as cancer a...

journal_title：Scientific reports

authors： Blanco JL,Porto-Pazos AB,Pazos A,Fernandez-Lozano C

更新日期：2018-10-24 00:00:00

abstract：:Herein, water-oxidation reaction by cobalt(II) phthalocyanine, N,N'-bis (salicylidene) ethylenediamino cobalt(II), nickel(II) Schiff base (N,N'-bis (salicylidene)ethylenediamino nickel(II), nickel(II)) phthalocyanine-tetrasulfonate tetrasodium, manganese(II) phthalocyanine, 5,10,15,20-Tetraphenyl-21H,23H-porphine mang...

journal_title：Scientific reports

authors： Najafpour MM,Feizi H

更新日期：2019-05-16 00:00:00

abstract：:Zircon of crustal origin found in mantle-derived rocks is of great interest because of the information it may provide about crust recycling and mantle dynamics. Consideration of this requires understanding of how mantle temperatures, notably higher than zircon crystallization temperatures, affected the recycled zircon...

journal_title：Scientific reports

authors： Bea F,Montero P,Palma JFM

更新日期：2018-08-27 00:00:00

abstract：:We investigate the behaviour of the recently proposed Quantum PageRank algorithm, in large complex networks. We find that the algorithm is able to univocally reveal the underlying topology of the network and to identify and order the most relevant nodes. Furthermore, it is capable to clearly highlight the structure of...

journal_title：Scientific reports

authors： Paparo GD,Müller M,Comellas F,Martin-Delgado MA

更新日期：2013-10-04 00:00:00

abstract：:The G protein-coupled receptor opsin is a phospholipid scramblase that facilitates rapid transbilayer phospholipid exchange in liposomes. The mechanism by which opsin scrambles lipids is unknown. It has been proposed that lipid translocation may occur at protein-protein interfaces of opsin dimers. To test this possibi...

journal_title：Scientific reports

authors： Pandey K,Ploier B,Goren MA,Levitz J,Khelashvili G,Menon AK

更新日期：2017-12-01 00:00:00

abstract：:The circadian clock confers daily rhythmicity on many biochemical and physiological functions and its disruption is associated with increased risks of developing obesity, diabetes, heart disease and cancer. Although, there are studies on the role of Bmal1 in carcinogenesis using germline, conditional or tissue-specifi...

journal_title：Scientific reports

authors： Korkmaz T,Aygenli F,Emisoglu H,Ozcelik G,Canturk A,Yilmaz S,Ozturk N

更新日期：2018-10-30 00:00:00

abstract：:Yinchenhao decoction (YCHD), comprising Yinchenhao (Artemisiae Scopariae Herba), Zhizi (Gardeniae Fructus) and Dahuang (Radix Rhei et Rhizoma), is widely used for treating various diseases. We aimed to investigate the bile acid metabolic mechanism of YCHD in dimethylnitrosamine (DMN)-induced liver fibrosis model. Rats...

journal_title：Scientific reports

authors： Cai FF,Wu R,Song YN,Xiong AZ,Chen XL,Yang MD,Yang L,Hu Y,Sun MY,Su SB

更新日期：2018-10-18 00:00:00

abstract：:N-α-acetyltransferase 10 (Naa10) displays alpha (N-terminal) acetyltransferase activity. It functions as a major modulator of cell growth and differentiation. Until now, a few downstream targets were found, but no studies have concerned about which gene is the early event of Naa10 downstream target. As we know, the ea...

journal_title：Scientific reports

authors： Xu H,Han Y,Liu B,Li R

更新日期：2016-12-02 00:00:00

abstract：:Maize rough dwarf virus (MRDV) is one of the main yield-limiting factors of maize in the Mediterranean. However, knowledge about the interactions between the agroecosystem and the virus-vector-host relationship continues to be limited. We used multi-model inference to test a landscape-scale approach together with vari...

journal_title：Scientific reports

authors： Clemente-Orta G,Albajes R,Batuecas I,Achon MA

更新日期：2021-01-13 00:00:00

abstract：:Altered neural mechanisms are well-acknowledged in irritable bowel syndrome (IBS), a disorder of brain-gut-communication highly comorbid with anxiety and depression. As a key hub in corticolimbic inhibition, medial prefrontal cortex (mPFC) may be involved in disturbed emotion regulation in IBS. However, aberrant mPFC ...

journal_title：Scientific reports

authors： Icenhour A,Tapper S,Bednarska O,Witt ST,Tisell A,Lundberg P,Elsenbruch S,Walter S

更新日期：2019-09-19 00:00:00

abstract：:The 2011 Tohoku earthquake drastically changed human activities in some regions of Fukushima Prefecture, Japan. The subsequent tsunami damage and radioactive pollution from the Fukushima Daiichi nuclear power plant resulted in the evacuation of humans, and abandonment of agricultural lands, allowing population expansi...

journal_title：Scientific reports

authors： Anderson D,Toma R,Negishi Y,Okuda K,Ishiniwa H,Hinton TG,Nanba K,Tamate HB,Kaneko S

更新日期：2019-08-08 00:00:00

abstract：:The protective effects of statins against stenosis for permanent hemodialysis access have been repeatedly demonstrated in animal studies, but remain controversial in human studies. This study aims to evaluate the association between statin use and permanent hemodialysis access patency using a nationwide hemodialysis c...

journal_title：Scientific reports

authors： Chang HH,Chang YK,Lu CW,Huang CT,Chien CT,Hung KY,Huang KC,Hsu CC

更新日期：2016-02-23 00:00:00

abstract：:Recently, lubricant-impregnated surfaces (LIS) have emerged as a promising condenser surface by facilitating the removal of condensates from the surface. However, LIS has the critical limitation in that lubricant oil is depleted along with the removal of condensates. Such oil depletion is significantly aggravated unde...

journal_title：Scientific reports

authors： Seo D,Shim J,Lee C,Nam Y

更新日期：2020-02-19 00:00:00

abstract：:Confident characterization of the microheterogeneity of protein glycosylation through identification of intact glycopeptides remains one of the toughest analytical challenges for glycoproteomics. Recently proposed mass spectrometry (MS)-based methods still have some defects such as lack of the false discovery rate (FD...

journal_title：Scientific reports

authors： Zeng WF,Liu MQ,Zhang Y,Wu JQ,Fang P,Peng C,Nie A,Yan G,Cao W,Liu C,Chi H,Sun RX,Wong CC,He SM,Yang P

更新日期：2016-05-03 00:00:00

abstract：:Repetitive transcranial magnetic stimulation (rTMS) has been proposed as a tinnitus treatment option. Promising results have been obtained by consecutive stimulation of lateral frontal and auditory brain regions. We investigated a combined stimulation paradigm targeting the anterior cingulate cortex (ACC) with double ...

journal_title：Scientific reports

authors： Kreuzer PM,Lehner A,Schlee W,Vielsmeier V,Schecklmann M,Poeppl TB,Landgrebe M,Rupprecht R,Langguth B

更新日期：2015-12-15 00:00:00

abstract：:The study utilizes autofluorescence spectroscopy (AFS) along with multivariate spectral analysis for differentiating various stages of hepatic fibrosis. AFS has recently emerged as an efficient tool for evaluating the variations in different endogenous flurophores. In this study, the potential of AFS for differentiati...

journal_title：Scientific reports

authors： Nazeer SS,Saraswathy A,Shenoy SJ,Jayasree RS

更新日期：2018-07-20 00:00:00

abstract：:Lipid droplet (LD), a multi-functional organelle, is often found to associate with other cellular membranous structures and vary in size in a given cell, which may be related to their functional diversity. Here we established a method to separate LD subpopulations from isolated CHO K2 LDs into three different size cat...

journal_title：Scientific reports

authors： Zhang S,Wang Y,Cui L,Deng Y,Xu S,Yu J,Cichello S,Serrero G,Ying Y,Liu P

更新日期：2016-07-08 00:00:00

abstract：:Soil fauna are critical for ecosystem function and sensitive to the changes of soil fertility. The effects of fertilization on soil fauna communities, however, remain poorly understood. We examined the effects of fertilization form and quantity on the abundance, diversity and composition of soil fauna across an age-se...

journal_title：Scientific reports

authors： Wang S,Chen HY,Tan Y,Fan H,Ruan H

更新日期：2016-02-09 00:00:00

abstract：:Doping with the optimum concentration of carriers (electrons or holes) can modify the physical properties of materials. Therefore, improved ways to achieve carrier doping have been pursued extensively for more than 50 years. Metal-intercalation is one of the most important techniques for electron doping of organic / i...

journal_title：Scientific reports

authors： Takahei Y,Tomita K,Itoh Y,Ashida K,Lee JH,Nishimoto N,Kimura T,Kudo K,Nohara M,Kubozono Y,Kambe T

更新日期：2016-01-06 00:00:00

abstract：:Porphyra 334 (P334), a mycosporine-like amino acid (MAA), is a secondary metabolite found in diverse marine and terrestrial organisms and has several beneficial effects on fibroblast proliferation, wound healing, and antioxidant activity. Here, we report that P334 accelerates the cell reprogramming process of mouse ta...

journal_title：Scientific reports

authors： Yoo J,Kim J,Lee JH,Kim H,Jang SJ,Seo HH,Oh ST,Hyeon SJ,Ryu H,Kim J,Moh SH

更新日期：2020-02-28 00:00:00