Abstract:
OBJECTIVES:The caries preventive effect of long-term use (1 year) of low-dosage (2.5 g/die) of xylitol chewing gum in a high-caries-risk adult population was evaluated. MATERIALS AND METHODS:In this randomized clinical trial, 179 high-caries-risk adults were assigned to two experimental groups, xylitol and polyols. Caries status, salivary mutans streptococci (MS), and plaque pH were re-evaluated after 2 years from baseline in 66 xylitol and 64 polyol subjects. Outcomes (the net caries increment for initial, moderate, and extensive caries lesions and for the caries experience) were evaluated using the nonparametric Mann-Whitney U test. RESULTS:The total caries experience increment was 1.25 ± 1.26 in the xylitol group and 1.80 ± 2.33 in the polyol group (p = 0.01). Subjects treated with xylitol chewing gums had a reduction of risk rate at tooth level of 23% with respect to those treated with polyols with a number needed to treat of 55 teeth. The area under the curve at pH 5.7 was statistically significantly lower (p = 0.02) during the experimental period in the xylitol group. A decrease of the concentration of salivary MS was noted in the xylitol group (p < 0.01). CONCLUSIONS:Subjects using the low-dose xylitol chewing gum showed a significantly lower increment of initial and extensive caries lesions and overall a lower increment of caries experience. CLINICAL RELEVANCE:One-year use of chewing gums provides an effective means for the prevention of caries disease. TRIAL REGISTRATION NUMBER:NCT02310308.
journal_name
Clin Oral Investigjournal_title
Clinical oral investigationsauthors
Cocco F,Carta G,Cagetti MG,Strohmenger L,Lingström P,Campus Gdoi
10.1007/s00784-017-2075-5subject
Has Abstractpub_date
2017-12-01 00:00:00pages
2733-2740issue
9eissn
1432-6981issn
1436-3771pii
10.1007/s00784-017-2075-5journal_volume
21pub_type
杂志文章,随机对照试验abstract:OBJECTIVES:The purpose of this study is to compare pressures at the apical foramen created by conventional syringe irrigation and the GentleWave™ System, which releases high-velocity degassed irrigants to the pulp chamber and uses broad-spectrum sound energy for cleaning. MATERIALS AND METHODS:The apical pressure gene...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-015-1632-z
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVE:The present study aimed to identify and quantify the elution of monomers of five different resin-based CAD/CAM blocks (RCBs) using HPLC. METHODS:Five different RCBs were used in the study: GC Cerasmart (CS), Voco Grandio blocs (GR), 3M Lava Ultimate (LU), Shofu Block (SB), and Vita Enamic (VE). Fifteen sampl...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03377-3
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVES:The aim of this research was to analyse the dental discolouration caused by mineral trioxide aggregate (MTA) induced by bismuth oxide and also assess the colour stability of other dental cements. MATERIALS AND METHODS:Bismuth oxide, calcium tungstate and zirconium oxide were placed in contact with sodium hy...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-015-1466-8
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to evaluate impact of periodontal surgery on periodontal health and on glycaemia control of type 1 and type 2 (T1DM; T2DM) diabetics with severe periodontitis, during 12 months follow-up, in comparison with non-diabetic controls. MATERIALS AND METHODS:A total of 23 T1DM and 10...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1819-y
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to compare temperature variation during osteotomies with trephine drills under different irrigation conditions: without irrigation, external irrigation, and double irrigation. MATERIALS AND METHODS:Synthetic blocks of bone (type I density) were used for drilling procedures with ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1163-4
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVES:The current study aimed to evaluate different CBCT exposure protocols and influencing factors affecting the subjective image quality of scans taken for endodontic indications. MATERIALS AND METHODS:Twelve extracted teeth, comprising of two sets of maxillary molars, premolars, canines and incisors, mandibula...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03524-w
更新日期:2020-08-25 00:00:00
abstract:OBJECTIVE:The objective of the present study is to investigate if changes in the oxygen saturation of masseter muscle during a chewing task can differentiate patients with myogenic temporomandibular disorders (TMD) from healthy subjects and if these differences are related to the gravity of the disorder and to the orof...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1912-2
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to assess whether alveolar ridge preservation (ARP) can reduce the need of ridge augmentation at posterior tooth sites. MATERIAL AND METHODS:This study enrolled patients who received dental implants at posterior tooth sites during 2013-2019. Demographic data and dental treatment hi...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-021-03778-y
更新日期:2021-01-11 00:00:00
abstract:OBJECTIVES:We aimed to determine the immunolocalization patterns of the interleukin (IL)-6 signaling complex in epithelialized and non-epithelialized apical lesions of endodontic origin (ALEOs). MATERIALS AND METHODS:Epithelialized (n = 8) and non-epithelialized (n = 7) ALEOs were obtained from teeth with indication o...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03738-y
更新日期:2021-01-07 00:00:00
abstract:BACKGROUND:The aim of this study was to evaluate through a systematic review the extraction of third molars as a risk factor for temporomandibular disorders (TMDs). TYPES OF STUDIES REVIEWED:Randomized and nonrandomized controlled clinical trials where patients underwent third molar extraction and with qualitative eva...
journal_title:Clinical oral investigations
pub_type: 杂志文章,评审
doi:10.1007/s00784-020-03277-6
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVES:Candida albicans is a common fungal infection and is commensal in 40-65 % of healthy adults. The development and pharmacokinetics of a novel sustained release clotrimazole varnish (Clot-SRV) for topical oral use have been reported. The aim of this study was to compare the efficacy of this varnish with clotri...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-014-1259-5
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVES:This study was designed to investigate the antimicrobial properties, compressive strength and fluoride release capacities of high-viscous glass ionomer cements (GICs) after incorporation of cinnamon and thyme essential oils. MATERIALS AND METHODS:Experimental-modified GICs were prepared by incorporation of ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03493-0
更新日期:2020-08-15 00:00:00
abstract:OBJECTIVES:To explore whether a computed tomography (CT) examination of the head and neck region induces biological damage and whether the damage was correlated with the radiation dose. MATERIALS AND METHODS:Peripheral blood was taken from 33 individuals who received head and neck CT examinations. Blood samples were d...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03331-3
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVES:To investigate the relationship between sleep disorders, morning hyposalivation, and subjective feeling of dry mouth. MATERIALS AND METHODS:A cross-sectional, observational, clinical study was carried out in a homogenous population sample which consists of Greek male soldiers without any medical history. Af...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-03029-1
更新日期:2020-05-01 00:00:00
abstract::The aim of the study was to monitor changes in oral health and oral biofilm composition in vivo during an experiment simulating prehistoric lifestyle and diet and poor oral hygiene. Thirteen subjects lived for a period of 8 weeks under Neolithic conditions. The following clinical parameters were recorded before and af...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-009-0318-9
更新日期:2010-08-01 00:00:00
abstract::To present the safety profile, the early healing phase and the clinical outcomes at 24 weeks following treatment of human intrabony defects with open flap debridement (OFD) alone or with OFD and rhGDF-5 adsorbed onto a particulate β-tricalcium phosphate (β-TCP) carrier. Twenty chronic periodontitis patients, each with...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-011-0610-3
更新日期:2012-08-01 00:00:00
abstract::In the original version of this article, the following were noted for correction. ...
journal_title:Clinical oral investigations
pub_type: 已发布勘误
doi:10.1007/s00784-020-03657-y
更新日期:2020-10-26 00:00:00
abstract:OBJECTIVE:Dental materials and oral hygiene products may be responsible for oral contact allergic reactions. We aimed to determine the occurrence of allergies in patients with symptomatic oral lichen planus (OLP), oral lichenoid lesions (OLLs) and stomatitis and investigate if patch testing could identify contact aller...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-017-2053-y
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVE:To identify salivary metabolite biomarkers to differentiate patients with oral squamous cell carcinoma and oral epithelial dysplasia (OSCC/OED) from those with persistent suspicious oral mucosal lesions (PSOML). SUBJECTS AND METHODS:Whole unstimulated saliva samples were collected from age-, sex-, and race-m...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2777-3
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVES:The aim of the present retrospective cohort study was to assess the 5-year outcome and survival of secondary root canal treatments (2°RCT), exploring the influence of pre-, intra-, and post-operative variables. MATERIALS AND METHODS:One hundred thirty-two endodontically retreated teeth were radiographically...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-017-2229-5
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVES:The aim was to study self-image and the level of psychological symptoms in patients with symptoms attributed to their dental restorative materials. MATERIALS AND METHODS:A questionnaire containing questions regarding dental and medical history was answered by 257 participants, one group with local oral symp...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2707-4
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVE:The purpose of this double-blind, randomised trial was to compare the clinical performance of a hybrid composite (Clearfil AP-X, Kuraray, Tokyo) and a nanocomposite (Filtek Z350, 3M ESPE, St. Paul, MN) over a period of 2 years in non-carious class V lesions using a modified US Public Health Service (USPHS) sy...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-012-0780-7
更新日期:2013-04-01 00:00:00
abstract:OBJECTIVES:For well-defined deep (> 2/3 dentin extension) carious lesions, selective (SE) or stepwise (SW) carious tissue removals have been recommended, while there is limited comparative evidence for both. We compared SE and SW over 24 months in a randomized controlled trial. METHODS:A two-arm superiority trial was ...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-020-03536-6
更新日期:2021-02-01 00:00:00
abstract::At a dental office in Münster, Germany, the majority of gold inlays incorporated between July 1969 and August 1999 (n=2,071) in 531 patients were checked with reference to the dental records and assessed retrospectively to determine their longevity. One hundred seventy-five gold inlays were rated as failures (no longe...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s007840100119
更新日期:2001-09-01 00:00:00
abstract:OBJECTIVES:The present dental bleaching case report describes a new method that precisely quantifies the daily wearing-times of the bleaching product by inserting a microsensor in the acetate custom tray. The bleaching efficacy was also discussed since the patient was previously submitted to enamel microabrasion. METH...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2439-5
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVES:Τhis study aims at determining the ability of cone beam computed tomography (CBCT) to visualize critical-size defects (CSD) created at rat calvaria and filled with 75/25 w/w nano-hydroxyapatite/chitosan (nHAp/CS) scaffolds, prior to their histological investigation. MATERIALS AND METHODS:Thirty adult Spragu...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-02939-4
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:To develop and evaluate predictive nomogram for extended duration of surgery in patients following mandibular third molars (M3M) removal. MATERIALS AND METHODS:A retrospectively observational study was performed and designed. A credible random split-sample method was used to divide data into training and va...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03499-8
更新日期:2020-08-10 00:00:00
abstract::This study aims to evaluate the inclinations of right and left sides the mandibular fossa in Asian population using computed tomography (CT) images and determine its effects according to the parameters of gender, age, and asymmetry. CT images of the heads of 198 Asian subjects [95 females aged 44.2 ± 20.7 years, range...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0518-y
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to investigate the role of hyperbaric oxygen (HBO) in the healing of teeth extraction sockets and in alveolar ridge preservation. This may provide an experimental basis for the widespread application of HBO in oral implantation. METHODS:A total of 32 beagle dogs were included i...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-03117-2
更新日期:2020-08-01 00:00:00
abstract::The aim of the study was to investigate the temperature rise of a nanocomposite and a conventional hybrid dental composite during photopolymerization when cured with halogen curing lamp (QHT) and light-emitting diode (LED). Temperature rise during photopolymerization of two commercially available composites (Filtek Su...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-008-0236-2
更新日期:2009-09-01 00:00:00