Abstract:
OBJECTIVE:Dental materials and oral hygiene products may be responsible for oral contact allergic reactions. We aimed to determine the occurrence of allergies in patients with symptomatic oral lichen planus (OLP), oral lichenoid lesions (OLLs) and stomatitis and investigate if patch testing could identify contact allergies to dental materials and oral hygiene products in these patients. METHODS:Forty-nine patients (7 men, 42 women) aged 31 to 77 years (61 ± 10.3 years) with symptomatic OLP, OLL or stomatitis and 29 healthy age- and gender-matched control subjects were included. They underwent an interview, clinical examination, oral mucosal biopsy and epicutan testing to the European baseline series, a toothpaste and dental material series. RESULTS:Nineteen patients had OLP, 19 OLL and 11stomatitis. Oral burning/itching was the most common symptom (83.7%), and 65.3% patients had more than one symptom. Patients visited their dentist more often than the healthy subjects and had statistically higher DMF-T and DMF-S scores. Nineteen patients (38.8%) and 10 healthy control subjects (34.5%) had allergic contact reactions primarily to fragrance ingredients. No differences could be found between OLP, OLL, stomatitis and healthy controls with regard to allergic contact reactions. However, contact allergy to aroma substances differed significantly between the patients and the healthy control subjects (p = 0.02). This type of contact allergy was most common in patients with OLP and OLL (p = 0.01). Avoidance cleared symptoms in all cases. CONCLUSION/CLINICAL RELEVANCE:Allergic reactions to aroma substances in oral hygiene products are common in patients with symptomatic OLP, OLL and stomatitis.
journal_name
Clin Oral Investigjournal_title
Clinical oral investigationsauthors
Larsen KR,Johansen JD,Reibel J,Zachariae C,Pedersen AMLdoi
10.1007/s00784-017-2053-ysubject
Has Abstractpub_date
2017-11-01 00:00:00pages
2543-2551issue
8eissn
1432-6981issn
1436-3771pii
10.1007/s00784-017-2053-yjournal_volume
21pub_type
杂志文章abstract:OBJECTIVES:Targeted modifications of the bulk implant surfaces using bioactive agents provide a promising tool for improvement of the long-term bony and soft tissue integration of dental implants. In this study, we assessed the cellular responses of primary human gingival fibroblasts (HGF) to different surface modifica...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1784-5
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:The objective of the study is to compare skeletal and dental changes in class II patients treated with fixed functional appliances (FFA) that pursue different biomechanical concepts: (1) FMA (Functional Mandibular Advancer) from first maxillary molar to first mandibular molar through inclined planes and (2) H...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-017-2111-5
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVES:The corona disease (COVID-19) is developing into one of the greatest challenges for healthcare professionals around the world. In this article, we report the detailed actions taken in the Department of Conservative Dentistry and Periodontology, University Hospital, Ludwig-Maximilians-University (LMU), Munich...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03440-z
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVES:The purpose of this case series was to evaluate the new bone formation following guided bone regeneration (GBR) with a calcium phosphosilicate (CPS), alloplastic bone putty at peri-implant dehiscence defects and to assess survival rate of implants placed in the augmented sites after 12 months of function. M...
journal_title:Clinical oral investigations
pub_type: 杂志文章,多中心研究
doi:10.1007/s00784-014-1268-4
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVE:Intrapapillary injection (IPI) has been suggested to improve pulpal anesthesia of mandibular teeth and to avoid complications from inferior alveolar nerve block (IANB). This study aimed to determine and compare clinical efficacies and prostaglandin E2 (PGE2) levels between IPI and IANB. MATERIALS AND METHODS...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-019-02954-5
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to quantify the symmetry of the alveolar process of the maxilla and palate during the first year of life in healthy infants with the help of a semiautomatic segmentation technique. MATERIALS AND METHODS:Maxillary plaster models of seventy healthy babies at 0, 3, 6, 9, and 12 mo...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03403-4
更新日期:2020-06-24 00:00:00
abstract:OBJECTIVES:The purpose of this study is to compare pressures at the apical foramen created by conventional syringe irrigation and the GentleWave™ System, which releases high-velocity degassed irrigants to the pulp chamber and uses broad-spectrum sound energy for cleaning. MATERIALS AND METHODS:The apical pressure gene...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-015-1632-z
更新日期:2016-09-01 00:00:00
abstract::The aims of this study were to evaluate clinically and microbiologically the effects of two resin-modified glass-ionomer cements (RMGICs) used as liners after incomplete dentine caries removal and to identify Streptococcus mutans and Streptococcus sobrinus strains isolated from dentine samples, before and after indire...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-009-0304-2
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to compare mechanical sensitivity on the tongue using quantitative sensory testing (QST) and psychological factors using the General Health Questionnaire (GHQ) between burning mouth syndrome (BMS) patients and healthy participants. MATERIALS AND METHODS:Participants comprised 20 fe...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2488-9
更新日期:2019-02-01 00:00:00
abstract::We determined the effects of soluble or coated nanocrystalline hydroxyapatite paste (nano-HA) and enamel matrix derivative (EMD) on proliferation, adhesion, and migration of periodontal ligament fibroblasts (PDLs). Cultured PDLs were stimulated with nano-HA paste or EMD in a soluble form or were coated to the surface ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0570-7
更新日期:2012-06-01 00:00:00
abstract::The aim of the study was to monitor changes in oral health and oral biofilm composition in vivo during an experiment simulating prehistoric lifestyle and diet and poor oral hygiene. Thirteen subjects lived for a period of 8 weeks under Neolithic conditions. The following clinical parameters were recorded before and af...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-009-0318-9
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVE:The objective of this study is to examine the efficacy of erlotinib and gefitinib with respect to epidermal growth factor (EGF) and cetuximab response in head and neck cancer cell lines. MATERIALS AND METHODS:Five human head and neck carcinoma cell lines were treated with EGF, cetuximab, erlotinib, and gefit...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-015-1566-5
更新日期:2016-05-01 00:00:00
abstract::The aim of the study was the morphological analysis of coronal dentin caries and the modifications induced by different pretreatments with phosphoric acid or sodium hypochlorite. Carious dentin specimens were obtained from human molars affected by carious lesions. Specimens were divided in four groups and submitted to...
journal_title:Clinical oral investigations
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00784-003-0221-8
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVES:The study aimed at assessing, as primary objective, the periapical status and quality of root fillings, and, as secondary objective, the endodontic treatment need of a German urban population in a cross-sectional study 20 years after the first one. MATERIALS AND METHODS:Clinical and radiographic data of 353...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2566-z
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVES:Different studies suggest that inflammation as well as hypoxia leads to an increase of p53 protein levels. However, the implication of p53 during oral inflammatory processes is still unknown. The aim of this study was therefore to investigate the effect of hypoxia and inflammation on p53 regulation in human ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-015-1679-x
更新日期:2016-09-01 00:00:00
abstract::Periodontal ligament (PDL) cells have been associated with the regulation of periodontal repair processes by the differential expression of osteoprotegerin and RANKL in response to intermittent parathyroid hormone (PTH) resulting in a modified activity of bone-resorbing osteoclasts. Here, we examined the intracellular...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0541-z
更新日期:2012-04-01 00:00:00
abstract::This study compared shear bond strengths of six self-adhesive resin cements to zirconium oxide ceramic with and without air-particle abrasion. One hundred twenty zirconia samples were air-abraded (group SB; n = 60) or left untreated (group NO). Composite cylinders were bonded to the zirconia samples with either BisCem...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-009-0278-0
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:Our aim was to investigate the disease-free survival in patients with tongue squamous cell carcinoma receiving metronomic neoadjuvant chemotherapy with 5-fluorouracil prodrugs (UFT or S-1) plus bleomycin compared with those who had up-front surgery retrospectively. METHODS:In this retrospective study, 108 p...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2689-2
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVES:The aim of this retrospective cephalometric study was to compare treatment outcomes with "bite jumping appliance" (BJA) or Andresen-Häupl type activator. It especially focused on skeletal and dental structures in patients with class II malocclusion. The study hypothesis was that differences in treatment-rela...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-03115-4
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to compare temperature variation during osteotomies with trephine drills under different irrigation conditions: without irrigation, external irrigation, and double irrigation. MATERIALS AND METHODS:Synthetic blocks of bone (type I density) were used for drilling procedures with ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1163-4
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to examine the influence of experience and gender on the radiographic detection of proximal caries lesions and on therapeutic decisions. MATERIALS AND METHODS:A survey of 220 examiners (students and employees at three universities and dentists in the field) was taken using a standa...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-017-2078-2
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to assess current opinions, applied techniques, and materials for the restoration of endodontically treated teeth (ETT) in a nationwide survey in Germany. MATERIAL AND METHODS:Completed questionnaires from 1,648 dentists were returned (response rate 63%). RESULTS:In general, po...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-015-1505-5
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVES:The aim of this investigation was to assess the currently available evidence concerning the complications and risk factors influencing the outcome of autotransplantation of teeth in humans. MATERIALS AND METHODS:Electronic searches were conducted to identify randomized controlled and prospective clinical tr...
journal_title:Clinical oral investigations
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00784-015-1473-9
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to evaluate long-term (≥5 years) tooth survival after resective therapy of multi-rooted, periodontally treated teeth and investigate the influence of patient-, tooth-, and dentist-related risk factors on tooth loss. MATERIALS AND METHODS:A total of 128 patients with root-resected m...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-03091-9
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVES:An optimized oral health-related section and a video training were developed and validated for the interRAI suite of instruments. The latter is completed by professional non-dental caregivers and used in more than 40 countries to assess care needs of older adults. METHODS:The optimized oral health-related s...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03669-8
更新日期:2020-11-16 00:00:00
abstract:OBJECTIVES:To evaluate, longitudinally, the impacts of orthognathic surgery in patients with skeletal class II malocclusion on oral health-related quality of life (OHRQoL), temporomandibular disorders (TMD) and psychological symptoms. MATERIALS AND METHODS:Forty-three patients with skeletal class II malocclusion who w...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03709-3
更新日期:2021-01-07 00:00:00
abstract:AIM:The aim of this study was to compare the effectiveness of 2% articaine and 2% lignocaine in achieving adequate anesthesia in children between the age group of 6-13 years using inferior alveolar nerve block. METHODS:A triple blinded randomized controlled trial was conducted in 180 participants (90 patients- 2% arti...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-018-2775-5
更新日期:2019-09-01 00:00:00
abstract::The aim of the current study was to evaluate the prevalence of psychopathological symptoms in patients who self-reported different forms of bruxism by means of clinical and anamnestic diagnostic criteria. Eighty-five participants were divided into four groups as sleep bruxers (12), awake bruxers (24), sleep-awake brux...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-010-0492-9
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVES:Bisphosphonates and denosumab are antiresorptive drugs used for the treatment of osteoporosis and oncological tumors. A severe side effect is osteonecrosis of the jaw. Monocyte/macrophage dysfunction is considered to play a distinct role in osteonecrosis. THP-1 monocytic cells were used in this study to eluc...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-014-1358-3
更新日期:2015-07-01 00:00:00
abstract::This study aims to evaluate the inclinations of right and left sides the mandibular fossa in Asian population using computed tomography (CT) images and determine its effects according to the parameters of gender, age, and asymmetry. CT images of the heads of 198 Asian subjects [95 females aged 44.2 ± 20.7 years, range...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0518-y
更新日期:2012-04-01 00:00:00