Abstract：
:Many amorphous materials show spatially heterogenous dynamics, as different regions of the same system relax at different rates. Such a signature, known as Dynamic Heterogeneity, has been crucial to understand the nature of the jamming transition in simple model systems and is currently considered very promising to characterize more complex fluids of industrial and biological relevance. Unfortunately, measurements of dynamic heterogeneities typically require sophisticated experimental set-ups and are performed by few specialized groups. It is now possible to quantitatively characterize the relaxation process and the emergence of dynamic heterogeneities using a straightforward method, here validated on video microscopy data of hard-sphere colloidal glasses. We call this method Differential Variance Analysis (DVA), since it focuses on the variance of the differential frames, obtained subtracting images at different time-lags. Moreover, direct visualization of dynamic heterogeneities naturally appears in the differential frames, when the time-lag is set to the one corresponding to the maximum dynamic susceptibility. This approach opens the way to effectively characterize and tailor a wide variety of soft materials, from complex formulated products to biological tissues.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Pastore R,Pesce G,Caggioni Mdoi
10.1038/srep43496subject
Has Abstractpub_date
2017-03-14 00:00:00pages
43496issn
2045-2322pii
srep43496journal_volume
7pub_type
杂志文章abstract：:The majority of genes encoding photosynthesis-associated proteins in the nucleus are induced by light during photomorphogenesis, allowing plants to establish photoautotrophic growth. Therefore, optimizing the protein import apparatus of plastids, designated as the translocon at the outer and inner envelope membranes o...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76939-w
更新日期：2020-11-20 00:00:00
abstract：:Protein phosphorylation is an important type of post-translational modification that is involved in a variety of biological activities. Most phosphorylation events occur on serine, threonine and tyrosine residues in eukaryotes. In recent years, many phosphorylation sites have been identified as a result of advances in...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep24735
更新日期：2016-04-19 00:00:00
abstract：:Individuals who are well integrated into society have greater access to resources and tend to live longer. Why some individuals are socially isolated and others are not is therefore puzzling from an evolutionary perspective. Answering this question requires establishing the mix of intrinsic and contextual factors that...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-18104-4
更新日期：2017-12-19 00:00:00
abstract：:Micro- and nanoscale surface textures, when optimally designed, present a unique approach to improve surface functionalities. Coupling surface texture with shape memory polymers may generate reversibly tuneable surface properties. A shape memory polyetherurethane is used to prepare various surface textures including 2...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep23686
更新日期：2016-03-30 00:00:00
abstract：:Regime shift from grasslands to shrub-dominated landscapes occur worldwide driven by altered land-use and climate change, affecting landscape function, biodiversity, and productivity. Warming winter temperatures are a main driver of expansion of the native, evergreen shrub, Morella cerifera, in coastal landscapes. Shr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-65161-3
更新日期：2020-05-19 00:00:00
abstract：:We investigate collective modes in three dimensional (3D) gapless multi-Weyl semimetals with anisotropic energy band dispersions (i.e., with a positive integer J). For comparison, we also consider the gapless semimetals with the isotropic band dispersions (i.e. E ~ kJ). We calculate analytically long-wavelength plasma...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep34023
更新日期：2016-09-30 00:00:00
abstract：:Classification of histologic patterns in lung adenocarcinoma is critical for determining tumor grade and treatment for patients. However, this task is often challenging due to the heterogeneous nature of lung adenocarcinoma and the subjective criteria for evaluation. In this study, we propose a deep learning model tha...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-40041-7
更新日期：2019-03-04 00:00:00
abstract：:The outbreak of multidrug-resistant pathogenic bacteria made the discovery of novel control strategies necessary. Phages have regained attention for their specific lytic activity against pathogenic bacterium. A newly isolated phage infecting the clinical Escherichia coli isolates, including several multidrug-resistant...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-26004-4
更新日期：2018-05-24 00:00:00
abstract：:The global incidence of obesity has led to an increasing need for understanding the molecular mechanisms that drive this epidemic and its comorbidities. Quantitative real-time RT-PCR (RT-qPCR) is the most reliable and widely used method for gene expression analysis. The selection of suitable reference genes (RGs) is c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-03730-9
更新日期：2017-06-15 00:00:00
abstract：:Vitellogenin is the main yolk precursor protein in insect oocytes. It is synthesized in the fat body and released into the hemolymph. To reach the oocyte surface, vitellogenin must cross a single layer of follicular epithelium cells. The transport of vitellogenin across the follicular epithelium has been suggested to ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-52789-z
更新日期：2019-11-11 00:00:00
abstract：:Cortical spreading depolarisation (CSD), the neural mechanism underlying migraine aura, may cause headache by sensitising the trigeminal system. Photophobia, the most bothersome accompanying symptom during migraine attacks, is more prevalent in migraine with aura than in migraine without aura. Whether CSD plays a role...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-67948-w
更新日期：2020-07-10 00:00:00
abstract：:A microfluidic probe (MFP) is a mobile channel-less microfluidic system under which a fluid is injected from an aperture into an open space, hydrodynamically confined by a surrounding fluid, and entirely re-aspirated into a second aperture. Various MFPs have been developed, and have been used for applications ranging ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep11943
更新日期：2015-07-14 00:00:00
abstract：:The second-in-class proteasome inhibitor (PI) carfilzomib (Kyprolis, Cfz) has contributed to a substantial advancement in multiple myeloma treatment by improving patient survival and quality of life. A considerable portion of patients however display intrinsic resistance to Cfz. Our mechanistic understanding of intrin...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-40635-1
更新日期：2019-03-11 00:00:00
abstract：:Emerging evidence indicates the existence of a new class of cancer genes that act as "signal linkers" coordinating oncogenic signals between mutated and differentially expressed genes. While frequently mutated oncogenes and differentially expressed genes, which we term Class I cancer genes, are readily detected by mos...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-07481-5
更新日期：2017-08-01 00:00:00
abstract：:Classical Lotka-Volterra (LV) competition equation has shown that coexistence of competitive species is only possible when intraspecific competition is stronger than interspecific competition, i.e., the species inhibit their own growth more than the growth of the other species. Note that density effect is assumed to b...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-19044-9
更新日期：2018-01-19 00:00:00
abstract：:Genetic divergences among mammalian strains are presented phenotypically in various aspects of physical appearance such as body shape and facial features. Yet how genetic diversity is expressed in brain function still remains unclear. Functional connectivity has been shown to be a valuable approach in characterizing t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep21697
更新日期：2016-02-22 00:00:00
abstract：:Nucleoporins have been reported to regulate pluripotent biology, but how they do so remains partially characterized. This study examined the effects of nup155 gene disruption on mouse embryonic stem cells to gain insights into possible mechanisms by which nucleoporins regulate pluripotency in a pro-arrhythmogenic stem...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-49147-4
更新日期：2019-09-03 00:00:00
abstract：:The expression of aminoglycoside-modifying enzymes represents a survival strategy of antibiotic-resistant bacteria. Aminoglycoside 2'-N-acetyltransferase [AAC(2')] neutralizes aminoglycoside drugs by acetylation of their 2' amino groups in an acetyl coenzyme A (CoA)-dependent manner. To understand the structural featu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-78699-z
更新日期：2020-12-09 00:00:00
abstract：:The presence of well-vascularised, endosteal bone in the medullary region of long bones of nonavian dinosaurs has been invoked as being homologous to medullary bone, a specialised bone tissue formed during ovulation in birds. However, similar bone tissues can result as a pathological response in modern birds and in no...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep24858
更新日期：2016-04-26 00:00:00
abstract：:Metal-organic frameworks (MOFs) formed from metals and organic ligands, are crystalline materials that are degradable in aqueous medium, and capable of releasing Ca and Sr ions. In this manuscript, the ability of MOFs to degrade and release osteogenic Ca and Sr ions was investigated. MOFs were generated by choosing os...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-49536-9
更新日期：2019-09-10 00:00:00
abstract：:Childbearing women with rheumatoid (RA) and psoriatic arthritis (PsA) have significant peripartum issues. A retrospective anonymous RedCAP survey of peripartum period in females with RA/PsA in the RAPPORT registry was performed. Completed analyses included descriptive statistics, Chi-square and Fisher's exact test. 16...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-60451-2
更新日期：2020-02-28 00:00:00
abstract：:Despite the frequent use of ionising radiation (IR) in therapy and diagnostics and the unavoidable exposure to external radiation sources, our knowledge regarding the radiosensitivity of human blood cell populations is limited and published data, obtained under different experimental conditions, are heterogeneous. To ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-021-81058-1
更新日期：2021-01-28 00:00:00
abstract：:Human mesenchymal stem cells (MSCs) are adult multipotent cells that have plasticity and inhabit the stroma of diverse tissues. The potential utility of MSCs has been heavily investigated in the fields of regenerative medicine and cell therapy. However, MSCs represent diverse populations that may depend on the tissue ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-16788-2
更新日期：2017-12-07 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-60956-w
更新日期：2020-02-26 00:00:00
abstract：:Although physiological changes are the most evident indicators of skin aging by alteration of the skin's structure and function, we question whether skin aging is also affected by the structure and assembly process of the skin microbiome. We analysed the skin microbiomes of 73 healthy Chinese women in two age groups (...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-53266-3
更新日期：2019-11-14 00:00:00
abstract：:Transforming growth factor β-1 (TGFβ-1)-induced phosphorylation of transcription factors Smad2 and Smad3 plays a crucial role in the pathogenesis of idiopathic pulmonary fibrosis (IPF). However, the molecular regulation of Smad2/Smad3 proteins stability remains a mystery. Here, we show that ubiquitin carboxyl-terminal...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep33116
更新日期：2016-09-08 00:00:00
abstract：:Currently, diagnostic testing for Lyme disease is done by determination of the serologic responses to Borrelia burgdorferi antigens, with the exception of the early localized phase of disease where diagnosis must be done clinically. Here, we describe the use of microfluidics technology to develop a multiplexed rapid l...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep35069
更新日期：2016-10-11 00:00:00
abstract：:Although oxide-based resistive switching memory (OxRAM) is one of the strong next-generation high capacity memory candidates, it has the critical disadvantage that deviations of resistance levels is too severe to be adopted as a high capacity memory device. More specifically, it is known that the larger on/off current...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-35838-x
更新日期：2019-01-22 00:00:00
abstract：:Atomistic chemical inhomogeneities are anticipated to induce dissimilarities in surface potentials, which control corrosion initiation of alloys at the atomic scale. Precise understanding of corrosion is therefore hampered by lack of definite information describing how atomistic heterogeneities regulate the process. H...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep39525
更新日期：2016-12-21 00:00:00
abstract：:A bound state in the continuum (BIC) is an unusual localized state that is embedded in a continuum of extended states. Here, we present the general condition for BICs to arise from wave equation separability. Then we show that by exploiting perturbations of certain symmetry such BICs can be turned into resonances that...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep33394
更新日期：2016-09-19 00:00:00
