Spatial distribution of electrons near the Fermi level in the metallic LaB6 through accurate X-ray charge density study.

abstract：:Stroke is a leading cause of death and the leading cause of long-term disability, but its electrophysiological basis is poorly understood. Characterizing acute ischemic neuronal activity dynamics is important for understanding the temporal and spatial development of ischemic pathophysiology and determining neuronal ac...

journal_title：Scientific reports

authors： Wann EG,Wodeyar A,Srinivasan R,Frostig RD

更新日期：2020-12-08 00:00:00

abstract：:While there is a rich literature on transcription dynamics during the development of many organisms, protein data is limited. We used iTRAQ isotopic labeling and mass spectrometry to generate the largest developmental proteomic dataset for any animal. Expression dynamics of nearly 4,000 proteins of Xenopus laevis was ...

journal_title：Scientific reports

authors： Sun L,Bertke MM,Champion MM,Zhu G,Huber PW,Dovichi NJ

更新日期：2014-03-14 00:00:00

abstract：:Quantification of cellular antigens and their interactions via antibody-based detection methods are widely used in scientific research. Accurate high-throughput quantitation of these assays using general image analysis software can be time consuming and challenging, particularly when attempted by users with limited im...

journal_title：Scientific reports

authors： Law AMK,Yin JXM,Castillo L,Young AIJ,Piggin C,Rogers S,Caldon CE,Burgess A,Millar EKA,O'Toole SA,Gallego-Ortega D,Ormandy CJ,Oakes SR

更新日期：2017-11-16 00:00:00

abstract：:Age-hardening in Al alloys has been used for over a century to improve its mechanical properties. However, the lack of direct observation limits our understanding of the dynamic nature of the evolution of nanoprecipitates during age-hardening. Using in-situ (scanning) transmission electron microscopy (S/TEM) while hea...

journal_title：Scientific reports

authors： Liu C,Malladi SK,Xu Q,Chen J,Tichelaar FD,Zhuge X,Zandbergen HW

更新日期：2017-05-19 00:00:00

abstract：:As it is altered by ionizing radiation, the vascular network is considered as a prime target in limiting normal tissue damage and improving tumor control in radiation therapy. Irradiation activates endothelial cells which then participate in the recruitment of circulating cells, especially by overexpressing cell adhes...

journal_title：Scientific reports

authors： Jaillet C,Morelle W,Slomianny MC,Paget V,Tarlet G,Buard V,Selbonne S,Caffin F,Rannou E,Martinez P,François A,Foulquier F,Allain F,Milliat F,Guipaud O

更新日期：2017-07-13 00:00:00

abstract：:The factors regulating phytoplankton community composition play a crucial role in structuring aquatic food webs. However, consensus is still lacking about the mechanisms underlying the observed biogeographical differences in cell size composition of phytoplankton communities. Here we use a trait-based model to disenta...

journal_title：Scientific reports

authors： Acevedo-Trejos E,Brandt G,Bruggeman J,Merico A

更新日期：2015-03-09 00:00:00

abstract：:Ga-68 Prostate-Specific Membrane Antigen PET/CT is a new tool for the assessment of prostate cancer. Standard imaging time is 60 minutes post injection of radiotracer. At 60 minutes, there is physiologic accumulation of radiotracer in the urinary bladder which may cause some lesions in its vicinity to be obscured. Our...

journal_title：Scientific reports

authors： Barakat A,Yacoub B,Homsi ME,Saad Aldine A,El Hajj A,Haidar MB

更新日期：2020-02-17 00:00:00

abstract：:Fibrin polymerization is a necessary part of hemostasis but clots can obstruct blood vessels and cause heart attacks and strokes. The polymerization reactions are specific and controlled, involving strong knob-into-hole interactions to convert soluble fibrinogen into insoluble fibrin. It has long been assumed that clo...

journal_title：Scientific reports

authors： Chernysh IN,Nagaswami C,Purohit PK,Weisel JW

更新日期：2012-01-01 00:00:00

abstract：:The combination of navigation and robotics in spine surgery has the potential to accurately identify and maintain bone entry position and planned trajectory. The goal of this study was to examine the feasibility, accuracy and efficacy of a new robot-guided system for semi-automated, minimally invasive, pedicle screw p...

journal_title：Scientific reports

authors： Burström G,Balicki M,Patriciu A,Kyne S,Popovic A,Holthuizen R,Homan R,Skulason H,Persson O,Edström E,Elmi-Terander A

更新日期：2020-05-05 00:00:00

abstract：:The genetic data of 17 Y chromosome short tandem repeats in 146 unrelated donor residents in the provinces of Granada, Málaga, and Almería (GMA) were analyzed to determine the genetic legacy of the male inhabitants of the former Kingdom of Granada. A total of 139 unique haplotypes were identified. Observed allele freq...

journal_title：Scientific reports

authors： Saiz M,Alvarez-Cubero MJ,Lorente JA,Alvarez JC,Martinez-Gonzalez LJ

更新日期：2019-03-26 00:00:00

abstract：:Reporter gene imaging allows for non-invasive monitoring of molecular processes in living cells, providing insights on the mechanisms underlying pathology and therapy. A lysine-rich protein (LRP) chemical exchange saturation transfer (CEST) MRI reporter gene has previously been developed and used to image tumor cells,...

journal_title：Scientific reports

authors： Perlman O,Ito H,Gilad AA,McMahon MT,Chiocca EA,Nakashima H,Farrar CT

更新日期：2020-11-26 00:00:00

abstract：:De novo protein sequencing is essential for understanding cellular processes that govern the function of living organisms and all sequence modifications that occur after a protein has been constructed from its corresponding DNA code. By obtaining the order of the amino acids that compose a given protein one can then d...

journal_title：Scientific reports

authors： Boynton P,Di Ventra M

更新日期：2016-05-03 00:00:00

abstract：:Fc domain fusion can improve the therapeutic effects of relatively small biological molecules such as peptides, cytokines, and antibody fragments. Fc fusion proteins can also be used to enhance the cytotoxic effects of small bispecific antibodies (bsAbs). However, fragmentation of Fc fusion proteins, which mainly occu...

journal_title：Scientific reports

authors： Suzuki S,Annaka H,Konno S,Kumagai I,Asano R

更新日期：2018-11-22 00:00:00

abstract：:Infantile hemangiomas are the most common infantile benign vascular tumor. While most infantile hemangiomas proliferate then involute, some may persist and require treatment for reasons including risk of disfigurement or functional impairment. Treatments currently include observation, pharmacological therapy, laser, c...

journal_title：Scientific reports

authors： Zhang L,Yuan WE,Zheng JW

更新日期：2016-02-15 00:00:00

abstract：:End stage renal disease (ESRD) patients depend on hemodialysis (HD) as a life-sustaining treatment, but HD membrane properties play a critical role in blood activation during HD and can lead to severe patient outcomes. This study reports on a series of investigations on the common clinical HD membranes available in Ca...

journal_title：Scientific reports

authors： Westphalen H,Saadati S,Eduok U,Abdelrasoul A,Shoker A,Choi P,Doan H,Ein-Mozaffari F

更新日期：2020-09-09 00:00:00

abstract：:Perpendicularly magnetized tunnel junctions (p-MTJs) that contain synthetic antiferromagnetic (SAF) frames show promise as reliable building blocks to meet the demands of perpendicular magnetic anisotropy (PMA)-based spintronic devices. In particular, Co/Pd multilayer-based SAFs have been widely employed due to their ...

journal_title：Scientific reports

authors： Lee JB,An GG,Yang SM,Park HS,Chung WS,Hong JP

更新日期：2016-02-18 00:00:00

abstract：:Roots have important roles for plants to withstand adverse environmental conditions, including salt stress. Biostimulant application was shown to enhance plant resilience towards abiotic stresses. Here, we studied the effect of a tannin-based biostimulant on tomato (Solanum lycopersicum L.) grown under salt stress con...

journal_title：Scientific reports

authors： Campobenedetto C,Mannino G,Beekwilder J,Contartese V,Karlova R,Bertea CM

更新日期：2021-01-11 00:00:00

abstract：:Demand for clinical decision support systems in medicine and self-diagnostic symptom checkers has substantially increased in recent years. Existing platforms rely on knowledge bases manually compiled through a labor-intensive process or automatically derived using simple pairwise statistics. This study explored an aut...

journal_title：Scientific reports

authors： Rotmensch M,Halpern Y,Tlimat A,Horng S,Sontag D

更新日期：2017-07-20 00:00:00

abstract：:This observational study investigated the impact of hyponatremia resolution on the results of a comprehensive geriatric assessment (CGA) in 150 patients with age ≥70 years and serum sodium <130 mEq/L. The test battery including Barthel index of Activities of Daily Living (ADL) and various tests of neurocognitive funct...

journal_title：Scientific reports

authors： Brinkkoetter PT,Grundmann F,Ghassabeh PJ,Becker I,Johnsen M,Suaréz V,Schulz RJ,Streichert T,Burst V

更新日期：2019-08-29 00:00:00

abstract：:Aquaporin 9 (AQP9), as an aquaglyceroporin, is expressed in many immune cells and plays important role in tumor initiation and progression. However, the relationship between AQP9 and tumor-infiltrating cells, and its prognostic value in cancers still require comprehensive understanding. Herein, we aimed to elucidate t...

journal_title：Scientific reports

authors： Liu X,Xu Q,Li Z,Xiong B

更新日期：2020-11-27 00:00:00

abstract：:Surface plasmon polaritons (SPPs) and standing wave modes provide interesting and exotic properties for infrared metamaterial absorbers. Coupling of these modes promises further development in this field but restricted by the complexity of modes analysis. In this work, we investigate the general phenomenon of modes co...

journal_title：Scientific reports

authors： Zhen G,Zhou P,Luo X,Xie J,Deng L

更新日期：2017-04-11 00:00:00

abstract：:Human travel impacts the spread of infectious diseases across spatial and temporal scales, with broad implications for the biological and social sciences. Individual data on travel patterns have been difficult to obtain, particularly in low-income countries. Travel survey data provide detailed demographic information,...

journal_title：Scientific reports

authors： Wesolowski A,Stresman G,Eagle N,Stevenson J,Owaga C,Marube E,Bousema T,Drakeley C,Cox J,Buckee CO

更新日期：2014-07-14 00:00:00

abstract：:Hypoxia-inducible factor (HIF)-1α and HIF-2α play an important role in liver fibrosis. von Hippel-Lindau protein (VHL), a key mediator of HIF-α, regulates fibrosis in an organ- and cell-specific way. In this study, human liver samples were collected from hepatitis C-, alcoholic-, and cholestatic-associated fibrotic an...

journal_title：Scientific reports

authors： Wang J,Lu Z,Xu Z,Tian P,Miao H,Pan S,Song R,Sun X,Zhao B,Wang D,Ma Y,Song X,Zhang S,Liu L,Jiang H

更新日期：2017-01-23 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the highest incidences in cancers; however, traditional chemotherapy often suffers from low efficiency caused by drug resistance. Herein, we report an arsenite-loaded dual-drug (doxorubicin and arsenic trioxide, i.e., DOX and ATO) nanomedicine system (FeAsOx@SiO2-DOX, Combo NP)...

journal_title：Scientific reports

authors： Liu H,Zhang Z,Chi X,Zhao Z,Huang D,Jin J,Gao J

更新日期：2016-08-03 00:00:00

abstract：:Graphene's unique physical and chemical properties make it an attractive platform for use in micro- and nanoelectronic devices. However, electrostatically controlling the flow of electrons in graphene can be challenging as a result of Klein tunneling, where electrons normally incident to a one-dimensional potential ba...

journal_title：Scientific reports

authors： Walls JD,Hadad D

更新日期：2015-02-13 00:00:00

abstract：:Anhedonia, the diminished ability to experience pleasure, is a challenging negative symptom in patients with schizophrenia and can be observed in at-risk individuals with schizotypy. Deficits in hedonic processing have been postulated to be related to decreased motivation to engage in potentially rewarding events. It ...

journal_title：Scientific reports

authors： Li X,Li Z,Li K,Zeng YW,Shi HS,Xie WL,Yang ZY,Lui SS,Cheung EF,Leung AW,Chan RC

更新日期：2016-10-18 00:00:00

abstract：:Microalgae have great potential for the production of biofuels due to the ability of the organism to accumulate large quantities of storage lipids under stress conditions. Mitogen activated protein kinase (MAPK) signaling cascades are widely recognized for their role in stress response signal transduction in eukaryote...

journal_title：Scientific reports

authors： Yang A,Suh WI,Kang NK,Lee B,Chang YK

更新日期：2018-09-14 00:00:00

abstract：:Global temperature changes have emphasized the need to understand how species adapt to thermal stress across their ranges. Genetic mechanisms may contribute to variation in thermal tolerance, providing evidence for how organisms adapt to local environments. We determine physiological thermal limits and characterize ge...

journal_title：Scientific reports

authors： Pimsler ML,Oyen KJ,Herndon JD,Jackson JM,Strange JP,Dillon ME,Lozier JD

更新日期：2020-10-13 00:00:00

abstract：:The neurology of male sexuality has been poorly studied owing to difficulties in studying brain circuitry in humans. Dopamine (DA) is essential for both physiological and behavioural responses, including the regulation of sexuality. Previous studies have revealed that alterations in DA synthesis in dopaminergic neuron...

journal_title：Scientific reports

authors： Chen SL,Chen YH,Wang CC,Yu YW,Tsai YC,Hsu HW,Wu CL,Wang PY,Chen LC,Lan TH,Fu TF

更新日期：2017-03-15 00:00:00

abstract：:In the field of correlative microscopy, light and electron microscopy form a powerful combination for morphological analyses in zoology. Due to sample thickness limitations, these imaging techniques often require sectioning to investigate small animals and thereby suffer from various artefacts. A recently introduced n...

journal_title：Scientific reports

authors： Ferstl S,Schwaha T,Ruthensteiner B,Hehn L,Allner S,Müller M,Dierolf M,Achterhold K,Pfeiffer F

更新日期：2020-03-03 00:00:00