Long-lasting alterations of hippocampal GABAergic neurotransmission in adult rats following perinatal Δ9-THC exposure.

abstract：:The aim of the present study was to investigate the effects of paradoxical sleep deprivation (PSD) for 96 h on the learning/memory processes in rats submitted to the plus-maze discriminative avoidance task (PM-DAT), which simultaneously evaluates learning, memory, anxiety and motor function. Four experiments were perf...

journal_title：Neurobiology of learning and memory

authors： Alvarenga TA,Patti CL,Andersen ML,Silva RH,Calzavara MB,Lopez GB,Frussa-Filho R,Tufik S

更新日期：2008-11-01 00:00:00

abstract：:Numerous experiments using ex vivo electrophysiology suggest that mammalian learning and memory involves regulation of voltage-gated ion channels in terms of changes in function. Yet, little is known about learning-related regulation of voltage-gated ion channels in terms of changes in expression. In two experiments, ...

journal_title：Neurobiology of learning and memory

authors： Fuchs JR,Darlington SW,Green JT,Morielli AD

更新日期：2017-07-01 00:00:00

abstract：:Adult Aplysia exhibit both short-term and long-term memory for sensitization in the gill and siphon withdrawal reflex. Previous developmental studies showed that short-term memory for sensitization emerges late in juvenile development (stage 12; Rankin and Carew, 1988; Wright et al., 1991). In the present study, we ex...

journal_title：Neurobiology of learning and memory

authors： Wright WG,McCance EF,Carew TJ

更新日期：1996-05-01 00:00:00

abstract：:Adolescence is characterized by major developmental changes that may render the individual vulnerable to stress and the development of psychopathologies in a sex-specific manner. Earlier we reported lower anxiety-like behavior and higher risk-taking and novelty seeking in rats previously exposed to peri-pubertal stres...

journal_title：Neurobiology of learning and memory

authors： Toledo-Rodriguez M,Pitiot A,Paus T,Sandi C

更新日期：2012-07-01 00:00:00

abstract：:Transgenic mouse models of Alzheimer's disease (AD) with nonphysiologic overexpression of amyloid precursor protein (APP) exhibit various unnatural symptoms/dysfunctions. To overcome this issue, mice with single humanized App knock-in (KI) carrying Swedish (NL), Beyreuther/Iberian (F), and Arctic (G) mutations in diff...

journal_title：Neurobiology of learning and memory

authors： Masuda A,Kobayashi Y,Kogo N,Saito T,Saido TC,Itohara S

更新日期：2016-11-01 00:00:00

abstract：:Females experience depression, posttraumatic stress disorder (PTSD), and anxiety disorders at approximately twice the rate of males, but the mechanisms underlying this difference remain undefined. The effect of sex hormones on neural substrates presents a possible mechanism. We investigated the effect of ovariectomy a...

journal_title：Neurobiology of learning and memory

authors： McDermott CM,Liu D,Ade C,Schrader LA

更新日期：2015-02-01 00:00:00

abstract：:It is well established that neurons are plastic and can change the strength of their connections with other neurons depending on their recent history. While many molecular entities involved in plastic processes were already described, the role of a store-operated calcium channel ORAI1 in neuronal plasticity is not kno...

journal_title：Neurobiology of learning and memory

authors： Tshuva RY,Korkotian E,Segal M

更新日期：2017-04-01 00:00:00

abstract：:In a previous study, we found that in contrast to healthy controls, hydrocortisone administration had enhancing effects on memory in patients with borderline personality disorder (BPD). Because hydrocortisone acts on glucocorticoid receptors (GR) and mineralocorticoid receptors (MR), it is unclear which receptor media...

journal_title：Neurobiology of learning and memory

authors： Wingenfeld K,Kuehl LK,Janke K,Hinkelmann K,Eckert FC,Roepke S,Otte C

更新日期：2015-04-01 00:00:00

abstract：:Two experiments examined the effects of total stimulus preexposure on latent inhibition (LI) in a conditioned taste aversion procedure with rats. Experiment 1 varied the frequency and duration of saccharin preexposures. LI was an increasing function of the product of frequency x duration. Experiment 2 kept saccharin e...

journal_title：Neurobiology of learning and memory

authors： De la Casa G,Lubow RE

更新日期：1995-09-01 00:00:00

abstract：:In insects, cholinergic neurons are thought to transmit olfactory conditioned stimulus (CS) to the sites for associating the CS with unconditioned stimulus (US), but the types of acetylcholine (ACh) receptor used by neurons participating in the association have not been determined. In cockroaches, a type of nicotinic ...

journal_title：Neurobiology of learning and memory

authors： Watanabe H,Matsumoto CS,Nishino H,Mizunami M

更新日期：2011-01-01 00:00:00

abstract：:Recently developed neuroimaging and electrophysiological techniques are allowing us to answer fundamental questions about how behavioral states regulate our perception of the external environment. Studies using these techniques have yielded surprising insights into how sensory processing is affected at the earliest st...

journal_title：Neurobiology of learning and memory

authors： Aton SJ

更新日期：2013-11-01 00:00:00

abstract：:Non-selective inhibition of histone deacetylases (HDACs), enzymes that remove acetyl groups from histone core proteins, enhances cognition and NMDAR-dependent long-term potentiation at hippocampal CA3-CA1 synapses. It is not known whether this is a general mechanism by which HDACs modulate plasticity at other hippocam...

journal_title：Neurobiology of learning and memory

authors： Franklin AV,Rusche JR,McMahon LL

更新日期：2014-10-01 00:00:00

abstract：:Based on computational models of the hippocampus, it has been suggested that a possible mechanism for memory retrieval is pattern completion, wherein an autoassociative network recalls previous patterns of activity given noisy or degraded cues. However, there are few behavioral data examining pattern completion per se...

journal_title：Neurobiology of learning and memory

authors： Kirwan CB,Gilbert PE,Kesner RP

更新日期：2005-01-01 00:00:00

abstract：:Agmatine is a new putative neurotransmitter; however, the physiological role(s) of this endogenous released polyamine is still to be determined. We investigated its cognitive effect in an inhibitory avoidance task in adult rats. Agmatine (0.1, 1, 10, and 20 mg/kg) or saline was administered ip immediately after traini...

journal_title：Neurobiology of learning and memory

authors： Arteni NS,Lavinsky D,Rodrigues AL,Frison VB,Netto CA

更新日期：2002-09-01 00:00:00

abstract：:In spite of evidence about negative effects of Nandrolone Decanoate (ND) on cognitive and memory performance, the underlying mechanisms are complex and have remained unclear. This research examines the role of Calcineurin in synaptic plasticity and memory storage impairment in ND administrated adolescent male rats. Fo...

journal_title：Neurobiology of learning and memory

authors： Moradpour F,Moazedi AA,Pourmotabbed A,Zarei F

更新日期：2019-09-01 00:00:00

abstract：:Performing sequences of movements is a ubiquitous skill that involves dopamine transmission. However, it is unclear which components of the dopamine system contribute to which aspects of motor sequence learning. Here we used a genetic approach to investigate the relationship between different components of the dopamin...

journal_title：Neurobiology of learning and memory

authors： Baetu I,Burns NR,Urry K,Barbante GG,Pitcher JB

更新日期：2015-11-01 00:00:00

abstract：:The dynamics of learning in the Active Avoidance test was analyzed at the trials level as well as at the level of daily sessions, each comprising numerous trials. The two scales (large scale for the sessions and small scale for the trials) were demonstrated to be mutually independent. The intermediate derived scales (...

journal_title：Neurobiology of learning and memory

authors： Giuliani A,Mancini AM,Ghirardi O,Ramacci MT,Voronina T,Sirabella P,Colosimo A

更新日期：1996-01-01 00:00:00

abstract：:Pre-test exposure to training-related cues is known to improve subsequent retention performance. To identify brain regions engaged in processes promoted by retrieval cues, a brain imaging approach using the [6-14C]glucose autoradiographic technique was used. Sprague-Dawley rats trained in a brightness discrimination a...

journal_title：Neurobiology of learning and memory

authors： Boujabit M,Bontempi B,Destrade C,Gisquet-Verrier P

更新日期：2003-01-01 00:00:00

abstract：:Evidence indicating a role for the nucleus accumbens in the development of latent inhibition of learning has accumulated. Two experiments were conducted using Wistar rats to investigate this role directly. Experiment 1 used a conditioned emotional response paradigm to assess the effects of discrete electrolytic lesion...

journal_title：Neurobiology of learning and memory

authors： Tai CT,Cassaday HJ,Feldon J,Rawlins JN

更新日期：1995-07-01 00:00:00

abstract：:The cholinergic system has consistently been implicated in Pavlovian fear conditioning. Considerable work has been done to localize specific nicotinic receptor subtypes in the hippocampus and determine their functional importance; however, the specific function of many of these subtypes has yet to be determined. An al...

journal_title：Neurobiology of learning and memory

authors： Vago DR,Kesner RP

更新日期：2007-03-01 00:00:00

abstract：:Cerebellar damage occurs during developmental stages in three mutant mice (staggerer, hot-foot, and lurcher), causing disturbances in posture and equilibrium. During three tests of motor coordination, the performances of staggerer mutants was inferior to that of normal mice and did not improve with extended practice f...

journal_title：Neurobiology of learning and memory

authors： Lalonde R,Filali M,Bensoula AN,Lestienne F

更新日期：1996-03-01 00:00:00

abstract：:The present study examined the effects of posttraining ethanol administration upon retention of an appetitive task using a variety of retention behaviors associated with the task. Male C57BL/6J mice were individually trained to find a cheese pellet placed in the corner of an open field. Five behavioral measures were u...

journal_title：Neurobiology of learning and memory

authors： Ladner CJ,Babbini M,Davies DL,Parker ES,Alkana RL

更新日期：2001-01-01 00:00:00

abstract：:In a previous study, adult male Sprague-Dawley rats with unilateral, electrolytic entorhinal cortex lesions showed significant deficits in acquisition of a water maze task that measured working memory. The 10 days of testing used two trials per day with an intertrial interval of 1 h, and the rats with entorhinal damag...

journal_title：Neurobiology of learning and memory

authors： Glasier MM,Janis LS,Roof RL,Stein DG

更新日期：1999-01-01 00:00:00

abstract：:It has recently become widely appreciated that value-based decision making is supported by multiple computational strategies. In particular, animal and human behavior in learning tasks appears to include habitual responses described by prominent model-free reinforcement learning (RL) theories, but also more deliberati...

journal_title：Neurobiology of learning and memory

authors： Doll BB,Shohamy D,Daw ND

更新日期：2015-01-01 00:00:00

abstract：:Electrolytic lesions centered on the amygdaloid central nucleus (ACe) resulted in the inability of rats to acquire a Pavlovian conditional vocalization response. Conditioning consisted of pairing a light conditional stimulus with a tailshock unconditional stimulus (US). The thresholds of three unconditional responses ...

journal_title：Neurobiology of learning and memory

authors： Borszcz GS,Leaton RN

更新日期：2003-05-01 00:00:00

abstract：:Place navigation engrams acquired with intact brain can be retrieved with either eye and are stored in both hemispheres. The retrieval circuitry was examined by testing an overtrained rat under lidocaine inactivation of the hippocampus, visual cortex, and superior colliculus. Thirty-three hooded rats with implanted ca...

journal_title：Neurobiology of learning and memory

authors： Turner LF,Liu Z,Bures J

更新日期：1997-07-01 00:00:00

abstract：:Human genetic studies established MET gene as a risk factor for autism spectrum disorders. We have previously shown that signaling mediated by MET receptor tyrosine kinase, expressed in early postnatal developing forebrain circuits, controls glutamatergic neuron morphological development, synapse maturation, and corti...

journal_title：Neurobiology of learning and memory

authors： Xia B,Wei J,Ma X,Nehme A,Liong K,Cui Y,Chen C,Gallitano A,Ferguson D,Qiu S

更新日期：2021-01-29 00:00:00

abstract：:Differences in cytoarchitectural organization and connectivity distinguishes granular (or area 29, A29) and dysgranular (or area 30, A30) subdivisions of the retrosplenial cortex (RSC). Although increasing evidence supports the participation of RSC in contextual fear learning and memory, the contribution of each RSC s...

journal_title：Neurobiology of learning and memory

authors： Sigwald EL,de Olmos S,Lorenzo A

更新日期：2020-05-01 00:00:00

abstract：:Male songbirds learn to produce song within a limited phase early in life; however they continue to learn to recognize songs in adulthood. Studies looking at Zenk activation after exposure to songs learned early in life for song production and songs learned in adulthood show opposite patterns of activation, suggesting...

journal_title：Neurobiology of learning and memory

authors： McKenzie TL,Hernandez AM,MacDougall-Shackleton SA

更新日期：2006-11-01 00:00:00

abstract：:The hypotheses that the medial septal area (MSA) is critical for working memory and that MSA neural activity is positively regulated by cholinergic inputs leads to two testable predictions: (1) working memory can be bidirectionally modulated by muscarinic manipulations of the MSA and (2) muscarinic activation of the M...

journal_title：Neurobiology of learning and memory

authors： Givens B,Olton DS

更新日期：1995-05-01 00:00:00