Immunohistochemical study of peripolar cells of the sheep.

Abstract:

:The proposal that the cytoplasmic granules of glomerular peripolar cells (PPCs) of the adult sheep and lamb contain a kallikrein-like substance has been re-examined. After extensive characterisation and purification of anti-kallikrein antibodies, it was concluded that PPCs do not contain immunohistochemically detectable amounts of urinary kallikrein; nor do such cells appear to synthesise kallikrein as shown by hybridisation histochemistry studies. They are also not renin-immunopositive. On the other hand, a proportion of them exhibit neuron-specific enolase (NSE) immunoreactivity, unlike the apparently closely related visceral and parietal epithelial cells.

journal_name

J Anat

journal_title

Journal of anatomy

authors

Trahair JF,Gall JA,Alcorn D,Coghlan JP,Fernley R,Penschow J,Grattage LP,Johnston CI,Ryan GB

subject

Has Abstract

pub_date

1989-02-01 00:00:00

pages

125-32

eissn

0021-8782

issn

1469-7580

journal_volume

162

pub_type

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