Relationship between frequency of hypoglycemic episodes and changes in carotid atherosclerosis in insulin-treated patients with type 2 diabetes mellitus.

abstract：:Mammalian Eag1 (Kv10.1) potassium (K+) channels are widely expressed in the brain. Several mutations in the gene encoding human Eag1 K+ channel have been associated with congenital neurodevelopmental anomalies. Currently very little is known about the molecules mediating protein synthesis and degradation of Eag1 chann...

journal_title：Scientific reports

authors： Hsu PH,Ma YT,Fang YC,Huang JJ,Gan YL,Chang PT,Jow GM,Tang CY,Jeng CJ

更新日期：2017-01-18 00:00:00

abstract：:This paper presents an ultracompact tunable device for power splitting and switching by tuning the Fermi energy level of monolayer patternless graphene underneath a slotted multimode interference (MMI) coupler operating in the mid-infrared, λ = 9-11 μm. By introducing a high-index silicon slot in the central region of...

journal_title：Scientific reports

authors： Huang CC,Sun TC

更新日期：2019-09-04 00:00:00

abstract：:Haemodialysis effectively removes small solutes and smaller-sized middle molecules from the blood; however, the clearance of larger middle molecules, which have been associated with negative effects, is poor. The novel medium cut-off (MCO) dialysis membrane has larger pore sizes and a more open structure than other hi...

journal_title：Scientific reports

authors： Hulko M,Dietrich V,Koch I,Gekeler A,Gebert M,Beck W,Krause B

更新日期：2019-05-01 00:00:00

abstract：:Carcinoembryonic antigen (CEA) is the only blood based protein biomarker at present, used for preoperative screening of advanced colorectal cancer (CRC) patients to determine the appropriate curative treatments and post-surveillance screening for tumour recurrence. Current diagnostics for CRC detection have several li...

journal_title：Scientific reports

authors： Shamsuddin SH,Jayne DG,Tomlinson DC,McPherson MJ,Millner PA

更新日期：2021-01-12 00:00:00

abstract：:Grain boundaries (GBs) in graphene prepared by chemical vapor deposition (CVD) greatly degrade the electrical and mechanical properties of graphene and thus hinder the applications of graphene in electronic devices. The seamless stitching of graphene flakes can avoid GBs, wherein the identical orientation of graphene ...

journal_title：Scientific reports

authors： Yuan Q,Song G,Sun D,Ding F

更新日期：2014-10-07 00:00:00

abstract：:Patients with scirrhous gastric cancer (SGC) frequently develop peritoneal dissemination, which leads to poor prognosis. The secreted protein angiopoietin-like-4 (ANGPTL4), which is induced by hypoxia, exerts diverse effects on cancer progression. Here, we aimed to determine the biological function of ANGPTL4 in SGC c...

journal_title：Scientific reports

authors： Baba K,Kitajima Y,Miyake S,Nakamura J,Wakiyama K,Sato H,Okuyama K,Kitagawa H,Tanaka T,Hiraki M,Yanagihara K,Noshiro H

更新日期：2017-09-11 00:00:00

abstract：:Biosorption is a cost-effective and simple technique for removing heavy metals and rare earth elements from aqueous solution. Here, metals were recovered from aqueous solutions using phosphorylated dry baker's yeast cells. The cells were phosphorylated using cyclo-triphosphate, Na3P3O9. The total P content of the phos...

journal_title：Scientific reports

authors： Ojima Y,Kosako S,Kihara M,Miyoshi N,Igarashi K,Azuma M

更新日期：2019-01-18 00:00:00

abstract：:Oryza coarctata (KKLL; 2n = 4x = 48, 665 Mb) also known as Porteresia coarctata is an extreme halophyte species of genus Oryza. Using Illumina and Nanopore reads, we achieved the assembled genome size of 569.9 Mb, accounting 85.69% of the estimated genome size with N50 of 1.85 Mb and 19.89% repetitive region. We also ...

journal_title：Scientific reports

authors： Mondal TK,Rawal HC,Chowrasia S,Varshney D,Panda AK,Mazumdar A,Kaur H,Gaikwad K,Sharma TR,Singh NK

更新日期：2018-09-12 00:00:00

abstract：:Groundwater systems affected by various factors can exhibit complex fractal behaviors, whose reliable characterization however is not straightforward. This study explores the fractal scaling behavior of the groundwater systems affected by plant water use and river stage fluctuations in the riparian zone, using multifr...

journal_title：Scientific reports

authors： Sun H,Gu X,Zhu J,Yu Z,Zhang Y

更新日期：2019-10-28 00:00:00

abstract：:Light represents the principal signal driving circadian clock entrainment. However, how light influences the evolution of the clock remains poorly understood. The cavefish Phreatichthys andruzzii represents a fascinating model to explore how evolution under extreme aphotic conditions shapes the circadian clock, since ...

journal_title：Scientific reports

authors： Ceinos RM,Frigato E,Pagano C,Fröhlich N,Negrini P,Cavallari N,Vallone D,Fuselli S,Bertolucci C,Foulkes NS

更新日期：2018-06-08 00:00:00

abstract：:We report, for the first time, the generation of high-order harmonics in a spectral range between 200 eV and 1 keV with an unusual spectral property: only every 4(th) (4i + 1, i∈ℵ) harmonic line appears, whereas the usual high-harmonic spectra consist of every odd (2i + 1) harmonic. We attribute this unique property t...

journal_title：Scientific reports

authors： Seres J,Seres E,Landgraf B,Ecker B,Aurand B,Kuehl T,Spielmann C

更新日期：2014-02-28 00:00:00

abstract：:Microbial secondary metabolites are valuable resources for novel drug discovery. In particular, actinomycetes expressed a range of antibiotics against a spectrum of bacteria. In genus level, strain Allosalinactinospora lopnorensis CA15-2(T) is the first new actinomycete isolated from the Lop Nor region, China. Antimic...

journal_title：Scientific reports

authors： Huang C,Leung RK,Guo M,Tuo L,Guo L,Yew WW,Lou I,Lee SMY,Sun C

更新日期：2016-02-11 00:00:00

abstract：:The capacity of graphene oxide nanoparticles (nGOx) to reduce or increase As and metals availability in polluted soils was compared with that of zero valent iron nanoparticles (nZVI). The nanomaterials used in this study were characterized by X-ray techniques, CHNS-O analysis, dynamic light scattering, and microscopy ...

journal_title：Scientific reports

authors： Baragaño D,Forján R,Welte L,Gallego JLR

更新日期：2020-02-05 00:00:00

abstract：:Recently, there has been increasing interest in strategies to predict neurological recovery in cervical myelopathy (CM) based on clinical images of the cervical spine. In this study, we aimed to explore potential preoperative brain biomarkers that can predict postoperative neurological recovery in CM patients by using...

journal_title：Scientific reports

authors： Takenaka S,Kan S,Seymour B,Makino T,Sakai Y,Kushioka J,Tanaka H,Watanabe Y,Shibata M,Yoshikawa H,Kaito T

更新日期：2019-07-18 00:00:00

abstract：:The nuclear factor κB (NF-κB) pathway plays a key role in innate and adaptive immunity, cell proliferation and survival, inflammation and tumors development. MiR-146a is an immune system regulator that has anti-inflammatory function in multiple cell types and conditions. Here we demonstrate activation of canonical NF-...

journal_title：Scientific reports

authors： Venuti A,Musarra-Pizzo M,Pennisi R,Tankov S,Medici MA,Mastino A,Rebane A,Sciortino MT

更新日期：2019-03-26 00:00:00

abstract：:Protein ubiquitylation participates in a number of essential cellular processes including signal transduction and transcription, often by initiating the degradation of specific substrates through the 26S proteasome. Within the ubiquitin-proteasome system, deubiquitylating enzymes (DUBs) not only help generate and main...

journal_title：Scientific reports

authors： Hayama R,Yang P,Valverde F,Mizoguchi T,Furutani-Hayama I,Vierstra RD,Coupland G

更新日期：2019-11-19 00:00:00

abstract：:We report the transient memory device by means of a water soluble SSG (solid sodium with glycerine) paper. This material has a hydroscopic property hence it can be soluble in water. In terms of physical security of memory devices, prompt abrogation of a memory device which stored a large number of data is crucial when...

journal_title：Scientific reports

authors： Bae H,Lee BH,Lee D,Seol ML,Kim D,Han JW,Kim CK,Jeon SB,Ahn D,Park SJ,Park JY,Choi YK

更新日期：2016-12-05 00:00:00

abstract：:Previously, we cloned a new gene termed 'tongue cancer resistance-associated protein 1' (TCRP1), which modulates tumorigenesis, enhances cisplatin (cDDP) resistance in cancers, and may be a potential target for reversing drug resistance. However, the mechanisms for regulating TCRP1 expression remain unclear. Herein, w...

journal_title：Scientific reports

authors： Jia X,Zhang Z,Luo K,Zheng G,Lu M,Song Y,Liu H,Qiu H,He Z

更新日期：2017-06-16 00:00:00

abstract：:This corrects the article DOI: 10.1038/srep09989. ...

journal_title：Scientific reports

authors： Briefer EF,Maigrot AL,Mandel R,Briefer Freymond S,Bachmann I,Hillmann E

更新日期：2018-03-19 00:00:00

abstract：:Nanoliposomal formulation of C6-ceramide, a proapoptotic sphingolipid metabolite, presents an effective way to treat malignant tumor. Here, we provide evidence that acute treatment (30 min) of melanoma and breast cancer cells with nanoliposomal C6-ceramide (NaL-C6) may suppress cell migration without inducing cell dea...

journal_title：Scientific reports

authors： Zhang P,Fu C,Hu Y,Dong C,Song Y,Song E

更新日期：2015-03-20 00:00:00

abstract：:A universal technology for the encapsulative protection of unstable anionic species by highly stable layered metal oxide has been developed via the surface modification of a metal oxide nanosheet. The surface anchoring of (3-aminopropyl)triethoxysilane (APTES) on exfoliated titanate nanosheet yields a novel cationic m...

journal_title：Scientific reports

authors： Kim TW,Kim IY,Park DH,Choy JH,Hwang SJ

更新日期：2016-02-24 00:00:00

abstract：:From 2010 to 2012, large outbreaks of EV-A71-related- hand foot and mouth disease (HFMD) occurred annually in China. Some cases had neurological complications and were closely associated with fatal cardiopulmonary collapse, but not all children with central nervous system (CNS) involvement demonstrated a poor prognosi...

journal_title：Scientific reports

authors： Long L,Xu L,Xiao Z,Hu S,Luo R,Wang H,Lu X,Xu Z,Yao X,Zhou L,Long H,Gong J,Song Y,Zhao L,Luo K,Zhang M,Feng L,Yang L,Sheng X,Fan X,Xiao B

更新日期：2016-03-22 00:00:00

abstract：:We describe a multiplexed RNA aptamer selection to 19 different targets simultaneously using a microcolumn-based device, MEDUSA (Microplate-based Enrichment Device Used for the Selection of Aptamers), as well as a modified selection process, that significantly reduce the time and reagents needed for selections. We exp...

journal_title：Scientific reports

authors： Reinholt SJ,Ozer A,Lis JT,Craighead HG

更新日期：2016-07-19 00:00:00

abstract：:This study aimed to observe the morphological characteristics of a PGLA [poly(glycolide-co-L-lactide)] nerve conduit and regenerated nerve bundle in the human body using high-frequency ultrasound and examine functional recovery of the regenerated nerve using functional magnetic resonance imaging (fMRI) after neural pr...

journal_title：Scientific reports

authors： Gao D,Jiang JJ,Gu SH,Lu JZ,Xu L

更新日期：2017-04-13 00:00:00

abstract：:In this study, we aimed to disclose the association of pre- and post-stroke glycemic status with clinical outcome in patients with spontaneous intracerebral hemorrhage (sICH). It was a multicenter, prospective, observational cohort study, conducted in 13 hospitals in Beijing from January 2014 to September 2016. The as...

journal_title：Scientific reports

authors： Kang K,Lu J,Ju Y,Wang W,Shen Y,Wang A,Cao Z,Zhao X

更新日期：2019-12-13 00:00:00

abstract：:Domoic acid (DA, 1), a potent neurotoxin that causes amnesic shellfish poisoning, has been found in diatoms and red algae. While biosynthetic pathway towards DA from geranyl diphosphate and L-glutamate has been previously proposed, its late stage is still unclear. Here, six novel DA related compounds, 7'-methyl-isodom...

journal_title：Scientific reports

authors： Maeno Y,Kotaki Y,Terada R,Cho Y,Konoki K,Yotsu-Yamashita M

更新日期：2018-01-10 00:00:00

abstract：:Chimpanzees (Pan troglodytes), one of humankinds' closest living relatives, are known to hunt and consume the meat of various animal taxa. Although some researchers have presented indirect evidence that chimpanzees may also prey on tortoises, until now, direct observations of this behaviour did not exist. Here, we pro...

journal_title：Scientific reports

authors： Pika S,Klein H,Bunel S,Baas P,Théleste E,Deschner T

更新日期：2019-05-23 00:00:00

abstract：:Nitric oxide synthase like enzyme (NOS-like enzyme), which produces nitric oxide, participates in many biological processes. However it remains unidentified and highly controversial that plants do possess a NOS-like enzyme. In this paper, a novel arginine analogue NP1 was designed and developed for the direct identifi...

journal_title：Scientific reports

authors： Chang K,Guo T,Li P,Liu Y,Xu Y,Fang Y,Qian X

更新日期：2016-09-02 00:00:00

abstract：:Embryonic cryopreservation has a relatively low survival rate because of cytoskeletal damage. However, molecular anti-freezing mechanisms have been largely unexplored. This study investigated the significance of RhoA, involved in embryonic development, and the Rho/RhoA-associated kinase (ROCK) signalling pathway in cr...

journal_title：Scientific reports

authors： Gu M,Ni H,Sheng X,Pauciullo A,Liu Y,Guo Y

更新日期：2017-07-27 00:00:00

abstract：:Metabolomics studies of diseases associated with chronic alcohol consumption provide compelling evidence of several perturbed metabolic pathways. Moreover, the holistic approach of such studies gives insights into the pathophysiological risk factors associated with chronic alcohol-induced disability, morbidity and mor...

journal_title：Scientific reports

authors： Irwin C,Mienie LJ,Wevers RA,Mason S,Westerhuis JA,van Reenen M,Reinecke CJ

更新日期：2018-04-10 00:00:00