C6-ceramide nanoliposome suppresses tumor metastasis by eliciting PI3K and PKCζ tumor-suppressive activities and regulating integrin affinity modulation.

abstract：:The corrosion of steel in concrete is mainly due to the chemical reaction between the chloride ions and iron ions. Indeed, this is a serious threaten for reinforced concrete structure, especially for the reinforced concrete structure in the sea. So it is urgent and important to protect concrete against chloride ions c...

journal_title：Scientific reports

authors： Zeng L,Song R

更新日期：2013-11-28 00:00:00

abstract：:GABAA receptor-mediated inhibition depends on the maintenance of low level intracellular [Cl-] concentration, which in adult depends on neuron specific K+-Cl- cotransporter-2 (KCC2). Previous studies have shown that KCC2 was downregulated in both epileptic patients and various epileptic animal models. However, the tem...

journal_title：Scientific reports

authors： Chen L,Wan L,Wu Z,Ren W,Huang Y,Qian B,Wang Y

更新日期：2017-03-13 00:00:00

abstract：:We describe the development and clinical evaluation of an automated smartphone-linked sensor capable of chemical-free, quantitative measurement of hemoglobin concentration ([Hb]) in whole blood samples. We have demonstrated that our sensor could analyze an unprocessed blood specimen with a mean processing time of <8 s...

journal_title：Scientific reports

authors： Lee J,Song J,Choi JH,Kim S,Kim U,Nguyen VT,Lee JS,Joo C

更新日期：2020-05-25 00:00:00

abstract：:Murraya koenigii (MK) leaf being a rich source of bioactive secondary metabolites has received inordinate attention in drug development research. Formation of secondary plant metabolite(s) in medicinal plants depends on several factors and in this study the cause of variation in bioavailability and content of a vital ...

journal_title：Scientific reports

authors： Kandimalla R,Das M,Barge SR,Sarma PP,Koiri DJ,Devi A,Karki AK,Kumar A,Devi R,Pal BC,Talukdar NC,Samanta SK

更新日期：2020-11-18 00:00:00

abstract：:Blueberry juice is a healthy and nutritious food that has become increasingly popular worldwide. However, little is known about the microbial groups of this juice that can cause its spoilage. This study aimed to identify the main spoilage microorganisms in blueberry juice and explore whether a microchip pulsed electri...

journal_title：Scientific reports

authors： Zhu N,Yu N,Zhu Y,Wei Y,Hou Y,Zhang H,Sun AD

更新日期：2018-05-25 00:00:00

abstract：:Owing to the growing infectious diseases caused by eukaryotic and prokaryotic pathogens, it is urgent to develop novel antimicrobial agents against clinical pathogenic infections. Biofilm formation and invasion into the host cells are vital processes during pathogenic colonization and infection. In this study, we test...

journal_title：Scientific reports

authors： Yu Q,Li J,Zhang Y,Wang Y,Liu L,Li M

更新日期：2016-05-25 00:00:00

abstract：:We have investigated the emission from InGaN/GaN quantum disks grown on the tip of GaN nanorods. The emission at 3.21 eV from the InGaN quantum disk doesn't show a Stark shift, and it is linearly polarized when excited perpendicular to the growth direction. The degree of linear polarization is about 39.3% due to the a...

journal_title：Scientific reports

authors： Park Y,Chan CCS,Nuttall L,Puchtler TJ,Taylor RA,Kim N,Jo Y,Im H

更新日期：2018-05-25 00:00:00

abstract：:Climate indices based on sea surface temperature (SST) can synthesize information related to physical processes that describe change and variability in continental precipitation from floods to droughts. The South Atlantic Subtropical Dipole index (SASD) is based on the distribution of SST in the South Atlantic and fit...

journal_title：Scientific reports

authors： Wainer I,Prado LF,Khodri M,Otto-Bliesner B

更新日期：2014-06-13 00:00:00

abstract：:Social immunity forms an essential part of the defence repertoire of social insects. In response to infestation by the parasitic mite Varroa destructor and its associated viruses, honey bees (Apis mellifera L.) have developed a specific behaviour (varroa-sensitive hygiene, or VSH) that helps protect the colony from th...

journal_title：Scientific reports

authors： Mondet F,Kim SH,de Miranda JR,Beslay D,Le Conte Y,Mercer AR

更新日期：2016-05-03 00:00:00

abstract：:Dynamic Nuclear Polarization (DNP) has been introduced to overcome the sensitivity limitations of nuclear magnetic resonance (NMR) spectroscopy also of supported lipid bilayers. When investigated by solid-state NMR techniques the approach typically involves doping the samples with biradicals and their investigation at...

journal_title：Scientific reports

authors： Salnikov ES,Aisenbrey C,Aussenac F,Ouari O,Sarrouj H,Reiter C,Tordo P,Engelke F,Bechinger B

更新日期：2016-02-15 00:00:00

abstract：:Type 1 diabetes can be overcome by regulatory T cells (Treg) in NOD mice yet an efficient method to generate and maintain antigen-specific Treg is difficult to come by. Here, we devised a combination therapy of peptide/MHC tetramers and IL-2/anti-IL-2 monoclonal antibody complexes to generate antigen-specific Treg and...

journal_title：Scientific reports

authors： Izquierdo C,Ortiz AZ,Presa M,Malo S,Montoya A,Garabatos N,Mora C,Verdaguer J,Stratmann T

更新日期：2018-05-25 00:00:00

abstract：:Burley tobacco (Nicotiana Tabacum) is a chlorophyll-deficiency mutant. Nitrate is one precursor of tobacco-specific nitrosamines (TSNAs) and is largely accumulated in burley tobacco. To decrease nitrate accumulation in burley tobacco, glycerol, a polyhydric alcohol compound and physiological regulating material, was s...

journal_title：Scientific reports

authors： Li Y,Chang D,Yang H,Wang J,Shi H

更新日期：2018-09-05 00:00:00

abstract：:Three main surveillance systems (laboratory-confirmed, influenza-like illness (ILI) and nationwide Notifiable Infectious Diseases Reporting Information System (NIDRIS)) have been used for influenza surveillance in China. However, it is unclear which surveillance system is more reliable in developing influenza early wa...

journal_title：Scientific reports

authors： Yang X,Liu D,Wei K,Liu X,Meng L,Yu D,Li H,Li B,He J,Hu W

更新日期：2018-02-12 00:00:00

abstract：:Ultrafast betatron x-ray emission from electron oscillations in laser wakefield acceleration (LWFA) has been widely investigated as a promising source. Betatron x-rays are usually produced via self-injected electron beams, which are not controllable and are not optimized for x-ray yields. Here, we present a new method...

journal_title：Scientific reports

authors： Huang K,Li YF,Li DZ,Chen LM,Tao MZ,Ma Y,Zhao JR,Li MH,Chen M,Mirzaie M,Hafz N,Sokollik T,Sheng ZM,Zhang J

更新日期：2016-06-08 00:00:00

abstract：:The proportion of women who experience a depressive state after delivery differs between primiparas and multiparas, so it is important to clarify the different factors related to depression between the two groups. In this study, we confirmed the differences in depressive states, the perinatal period, and social suppor...

journal_title：Scientific reports

authors： Nakamura Y,Okada T,Morikawa M,Yamauchi A,Sato M,Ando M,Ozaki N

更新日期：2020-10-13 00:00:00

abstract：:The use of cardiac troponins (cTn) is the gold standard for diagnosing myocardial infarction. Independent of myocardial infarction (MI), however, sex, age and kidney function affect cTn levels. Here we developed a method to adjust cTnI levels for age, sex, and renal function, maintaining a unified cut-off value such a...

journal_title：Scientific reports

authors： Boeckel JN,Palapies L,Klotsche J,Zeller T,von Jeinsen B,Perret MF,Kleinhaus SL,Pieper L,Tzikas S,Leistner D,Bickel C,Stalla GK,Lehnert H,Lindahl B,Wittchen HU,Silber S,Baldus S,Maerz W,Dimmeler S,Blankenberg S,Mün

更新日期：2018-05-24 00:00:00

abstract：:Disordered proteins are highly prevalent in biological systems, they control myriad signaling and regulatory processes, and their levels and/or cellular localization are often altered in human disease. In contrast to folded proteins, disordered proteins, due to conformational heterogeneity and dynamics, are not consid...

journal_title：Scientific reports

authors： Iconaru LI,Ban D,Bharatham K,Ramanathan A,Zhang W,Shelat AA,Zuo J,Kriwacki RW

更新日期：2015-10-28 00:00:00

abstract：:Obesity is a major cause of type 2 diabetes mellitus (T2DM) in mammals. We have previously established a zebrafish model of diet-induced obesity (DIO zebrafish) by overfeeding Artemia. Here we created DIO zebrafish using a different method to induce T2DM. Zebrafish were overfed a commercially available fish food using...

journal_title：Scientific reports

authors： Zang L,Shimada Y,Nishimura N

更新日期：2017-05-03 00:00:00

abstract：:Our goal was to evaluate early results of the clinical application of autologous whole bone marrow stem cell transplantation (AWBMSCT) for critical limb ischemia (CLI) in patients with Buerger's disease. We retrospectively analyzed the data of 58 limbs of 37 patients (mean age, 43.0 years; range, 28-63 years; male, 91...

journal_title：Scientific reports

authors： Heo SH,Park YS,Kang ES,Park KB,Do YS,Kang KS,Kim DI

更新日期：2016-01-21 00:00:00

abstract：:We propose a scheme for generating an entangled state for two atoms trapped in two separate cavities coupled to each other. The scheme is based on the competition between the unitary dynamics induced by the classical fields and the collective decays induced by the dissipation of two non-local bosonic modes. In this sc...

journal_title：Scientific reports

authors： Jin Z,Su SL,Zhu AD,Wang HF,Shen LT,Zhang S

更新日期：2017-12-15 00:00:00

abstract：:Two yellow luminescence bands related to different defects have been revealed in undoped GaN grown by hydride vapor phase epitaxy (HVPE). One of them, labeled YL1, has the zero-phonon line (ZPL) at 2.57 eV and the band maximum at 2.20 eV at low temperature. This luminescence band is the ubiquitous yellow band observed...

journal_title：Scientific reports

authors： Reshchikov MA,McNamara JD,Helava H,Usikov A,Makarov Y

更新日期：2018-05-25 00:00:00

abstract：:The end-Triassic is characterized by one of the largest mass extinctions in the Phanerozoic, coinciding with major carbon cycle perturbations and global warming. It has been suggested that the environmental crisis is linked to widespread sill intrusions during magmatism associated with the Central Atlantic Magmatic Pr...

journal_title：Scientific reports

authors： Heimdal TH,Svensen HH,Ramezani J,Iyer K,Pereira E,Rodrigues R,Jones MT,Callegaro S

更新日期：2018-01-09 00:00:00

abstract：:Polymerized ionic liquids (polyILs) combine the unique properties of ionic liquids (ILs) with macromolecular polymers. But anion diffusivities in polyILs can be three orders of magnitude lower than that in ILs. Endeavors to improve ion transport in polyILs urgently need in-depth insights of ion transport in polyILs. A...

journal_title：Scientific reports

authors： Xiao W,Yang Q,Zhu S

更新日期：2020-05-08 00:00:00

abstract：:Endogenous stress represents a major source of genome instability, but is in essence difficult to apprehend. Incorporation of labeled radionuclides into DNA constitutes a tractable model to analyze cellular responses to endogenous attacks. Here we show that incorporation of [(3)H]thymidine into CHO cells generates oxi...

journal_title：Scientific reports

authors： Saintigny Y,Chevalier F,Bravard A,Dardillac E,Laurent D,Hem S,Dépagne J,Radicella JP,Lopez BS

更新日期：2016-07-11 00:00:00

abstract：:Extranodal NK/T-cell lymphoma, nasal type (NKTL) is an aggressive type of non-Hodgkin lymphoma closely associated with Epstein-Barr virus and characterized by varying degrees of systemic inflammation. We aim to examine the prognostic significance of peripheral blood neutrophil-lymphocyte ratio (NLR) in patients with N...

journal_title：Scientific reports

authors： Tan KM,Chia B,Lim JQ,Khoo LP,Cheng CL,Tan L,Poon E,Somasundaram N,Farid M,Tang TPL,Tao M,Cheah DMZ,Laurensia Y,Pang JWL,Song T,Tan J,Huang D,Kim SJ,Kim WS,Ong CK,Lim ST,Chan JY

更新日期：2019-10-18 00:00:00

abstract：:The clinical presentation of diabetes sometimes overlaps, contributing to ambiguity in the diagnosis. Thus, circulating pancreatic islet-enriched microRNAs (miRNAs) might be useful biomarkers of β-cell injury/dysfunction that would allow more accurate subtyping of diabetes. We measured plasma levels of selected miRNAs...

journal_title：Scientific reports

authors： Seyhan AA,Nunez Lopez YO,Xie H,Yi F,Mathews C,Pasarica M,Pratley RE

更新日期：2016-08-25 00:00:00

abstract：:Changes in the stability, hydrogen diffusion, and mechanical properties of the NbH phases from Ni-doping was studied by using first-principles methods. The calculation results reveal that the single H atom adsorption is energetically favorable at the tetrahedral interstitial site (TIS) and octahedral interstitial site...

journal_title：Scientific reports

authors： Wu Y,Wang Z,Wang D,Wan Z,Zhong Y,Hu C,Zhou H

更新日期：2017-07-26 00:00:00

abstract：:Recent emergence of metasurfaces has enabled the development of ultra-thin flat optical components through different wavefront shaping techniques at various wavelengths. However, due to the non-adaptive nature of conventional metasurfaces, the focal point of the resulting optics needs to be fixed at the design stage, ...

journal_title：Scientific reports

authors： Hosseininejad SE,Rouhi K,Neshat M,Faraji-Dana R,Cabellos-Aparicio A,Abadal S,Alarcón E

更新日期：2019-02-27 00:00:00

abstract：:Myogenic differentiation proceeds through a highly coordinated cascade of gene activation that necessitates epigenomic changes in chromatin structure. Using a screen of small molecule epigenetic probes we identified three compounds which inhibited myogenic differentiation in C2C12 myoblasts; (+)-JQ1, PFI-1, and Bromos...

journal_title：Scientific reports

authors： Roberts TC,Etxaniz U,Dall'Agnese A,Wu SY,Chiang CM,Brennan PE,Wood MJA,Puri PL

更新日期：2017-07-21 00:00:00

abstract：:The investigation of chemical and structural dynamics in battery materials is essential to elucidation of structure-property relationships for rational design of advanced battery materials. Spatially resolved techniques, such as scanning/transmission electron microscopy (S/TEM), are widely applied to address this chal...

journal_title：Scientific reports

authors： Lin F,Markus IM,Doeff MM,Xin HL

更新日期：2014-07-16 00:00:00