Obesity as a Risk Factor for Prostatic Enlargement: A Retrospective Cohort Study in Korea.

Abstract:

PURPOSE:We aimed to evaluate obesity, a risk factor of metabolic syndrome, and its association with prostatic enlargement in a retrospective cohort in Korea. METHODS:Baseline data were obtained from the Korean Genome and Epidemiology Study on Atherosclerosis Risk of Rural Areas in the Korean General Population (KoGES-ARIRANG). Between March 2015 and November 2015, 2,127 male participants of KoGES-ARIRANG were invited to the Korean Prostate Health Council Screening Program, and 602 participants underwent urological examination, including serum prostate specific antigen measurement and transrectal ultrasonography, and completed the International Prostate Symptom Score questionnaire. The data for 571 participants were analyzed, after excluding 31 men who had a history of prostatic disease or testosterone replacement, or had undergone a prior prostatic surgery or procedure. RESULTS:Among components of metabolic syndrome, waist circumference had a statistically significant linear correlation with incremental increases in prostate volume (B=0.181, P=0.004). Abdominal obesity as determined by anthropometric measures including body mass index (odds ratio [OR], 1.205; 95% confidence interval [CI], 1.088-1.336), waist circumference (OR, 1.073; 95% CI, 1.032-1.115), body fat (OR, 1.126; 95% CI, 1.056-1.202), and visceral fat composition (OR, 1.667; 95% CI, 1.246-2.232) was significantly associated with the presence of high-volume benign prostatic hyperplasia (BPH) (prostate volume≥ 40 mL). Furthermore, the highest quartile of serum leptin (OR, 3.541; 95% CI, 1.103-11.365) and adiponectin levels (OR, 0.315; 95% CI, 0.102-0.971) were significantly correlated with high-volume BPH compared to the lowest quartile of levels. CONCLUSIONS:Abdominal obesity and serum leptin level are positively associated with prostate growth, whereas serum adiponectin level is inversely associated with the presence of prostatic enlargement.

journal_name

Int Neurourol J

authors

Jung JH,Ahn SV,Song JM,Chang SJ,Kim KJ,Kwon SW,Park SY,Koh SB

doi

10.5213/inj.1632584.292

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

321-328

issue

4

eissn

2093-4777

issn

2093-6931

pii

inj-1632584-292

journal_volume

20

pub_type

杂志文章
  • Dissimilar effects of tolterodine on detrusor overactivity in awake rats with chemical cystitis and partial bladder outlet obstruction.

    abstract:PURPOSE:We investigated bladder function, with a special focus on nonvoiding contractions (NVCs), in awake rats with chronic chemical cystitis and bladder outlet obstruction (BOO) by use of simultaneous registrations of intravesical and intraabdominal pressures. In addition, we tested the effects of tolterodine on the ...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.2011.15.3.120

    authors: Jin LH,Park CS,Shin HY,Yoon SM,Lee T

    更新日期:2011-09-01 00:00:00

  • Role of Transcutaneous Electrical Nerve Stimulation in Treating Children With Overactive Bladder From Pooled Analysis of 8 Randomized Controlled Trials.

    abstract:PURPOSE:Transcutaneous electrical neural stimulation (TENS), as a non-invasive modality, has been clinically used as an alternative treatment for children with overactive bladder (OAB). We conducted a pooled analysis to explore the effect of TENS on OAB. METHODS:The Preferred Reporting Items for Systematic Reviews and...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1938232.116

    authors: Cui H,Yao Y,Xu Z,Gao Z,Wu J,Zhou Z,Cui Y

    更新日期:2020-03-01 00:00:00

  • Therapeutic Endoscopic Treatment Plus Maintenance Dimethyl Sulfoxide Therapy Prolongs Recurrence-Free Time in Patients With Hunner Type Interstitial Cystitis: A Pilot Study.

    abstract:PURPOSE:To evaluate whether hydrodistention with fulguration of Hunner lesions (HD/FUL) plus maintenance dimethyl sulfoxide (DMSO) therapy prolongs the recurrence-free time in patients with Hunner type interstitial cystitis (IC). METHODS:The study enrolled patients with Hunner type IC who required repeat HD/FUL due to...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1938110.055

    authors: Otsuka A,Suzuki T,Matsushita Y,Watanabe H,Tamura K,Motoyama D,Ito T,Sugiyama T,Miyake H

    更新日期:2019-12-01 00:00:00

  • Development of Decision Support Formulas for the Prediction of Bladder Outlet Obstruction and Prostatic Surgery in Patients With Lower Urinary Tract Symptom/Benign Prostatic Hyperplasia: Part I, Development of the Formula and its Internal Validation.

    abstract:PURPOSE:As the elderly population increases, a growing number of patients have lower urinary tract symptom (LUTS)/benign prostatic hyperplasia (BPH). The aim of this study was to develop decision support formulas and nomograms for the prediction of bladder outlet obstruction (BOO) and for BOO-related surgical decision-...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1734852.426

    authors: Choo MS,Yoo C,Cho SY,Jeong SJ,Jeong CW,Ku JH,Oh SJ

    更新日期:2017-04-01 00:00:00

  • Clinical Factors Associated With the Feeling of Incomplete Bladder Emptying in Women With Little Postvoided Residue.

    abstract:PURPOSE:To investigate the clinical factors associated with the feeling of incomplete bladder emptying in female patients with lower urinary tract symptoms (LUTS). METHODS:Records were obtained from a prospectively maintained database for 353 female patients without a history of treatment for LUTS. Patients with comor...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1938256.128

    authors: Lee KS,Koo KC

    更新日期:2020-06-01 00:00:00

  • Characterization on Responsiveness of Excitatory Synaptic Transmissions to α1-Adrenoceptor Blockers in Substantia Gelatinosa Neurons Isolated From Lumbo-Sacral Level in Rat Spinal Cords.

    abstract:PURPOSE:The aim of this study was to characterize the responsiveness of miniature excitatory postsynaptic currents (mEPSCs) to α1-adrenoceptor blockers in substantia gelatinosa (SG) neurons from the spinal cord to develop an explanation for the efficacy of α1-adrenoceptor blockers in micturition dysfunction. METHODS:M...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1938056.028

    authors: Uta D,Hattori T,Yoshimura M

    更新日期:2019-03-01 00:00:00

  • Alpha-Blocker Treatment Response in Men With Lower Urinary Tract Symptoms Based on Sympathetic Activity: Prospective, Multicenter, Open-Labeled, Observational Study.

    abstract:PURPOSE:In this study, we compared the treatment outcomes for an α-blocker between 2 groups of men, one with high sympathetic activity (HSA) and another with low sympathetic activity (LSA) or normal sympathetic activity. METHODS:A total of 159 men (≥50 years of age) with lower urinary tract symptoms resulting from ben...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.2015.19.2.107

    authors: Park SG,Chung BH,Lee SW,Park JK,Park K,Cheon J,Lee KS,Kim HJ,Seong DH,Oh SJ,Kim SW,Lee JY,Choo SH,Choi JB

    更新日期:2015-06-01 00:00:00

  • The Efficacy of Continuous Positive Airway Pressure Therapy on Nocturia in Patients With Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis.

    abstract:PURPOSE:To assess the efficacy of the continuous positive airway pressure (CPAP) on nocturia in patients with obstructive sleep apnea (OSA). METHODS:A literature review was performed to identify all published clinical trials of CPAP for the treatment of nocturia. The search included the following databases: MEDLINE, E...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.2015.19.3.178

    authors: Wang T,Huang W,Zong H,Zhang Y

    更新日期:2015-09-01 00:00:00

  • Past, Present, and Future in the Study of Neural Control of the Lower Urinary Tract.

    abstract::The neurological coordination of the lower urinary tract can be analyzed from the perspective of motor neurons or sensory neurons. First, sensory nerves with receptors in the bladder and urethra transmits stimuli to the cerebral cortex through the periaqueductal gray (PAG) of the midbrain. Upon the recognition of stim...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.2040318.159

    authors: Kim JW,Kim SJ,Park JM,Na YG,Kim KH

    更新日期:2020-09-01 00:00:00

  • Correlation Between Testosterone-Replacement Treatment and Lower Urinary Tract Symptoms.

    abstract::Lower urinary tract symptoms (LUTS) are a cluster of voiding symptoms, such as weak stream, hesitancy, intermittency, urinary frequency, urgency, and nocturia. LUTS are frequent in elderly men and it considered the ultimate clinical symptoms of benign prostatic hyperplasia. With aging, male hypogonadism is increased w...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.2040234.117

    authors: Lee MH,Shin YS,Kam SC

    更新日期:2021-01-19 00:00:00

  • Foreign Bodies in the Urinary Bladder and Their Management: A Single-Centre Experience From North India.

    abstract:PURPOSE:This study was performed to characterise the nature, clinical presentation, mode of insertion, and management of intravesical foreign bodies in patients treated at our hospital. METHODS:Between January 2008 and December 2014, 49 patients were treated for intravesical foreign bodies at King George Medical Unive...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1632524.262

    authors: Bansal A,Yadav P,Kumar M,Sankhwar S,Purkait B,Jhanwar A,Singh S

    更新日期:2016-09-01 00:00:00

  • Neurologic Mechanisms Underlying Voiding Dysfunction due to Prostatitis in a Rat Model of Nonbacterial Prostatic Inflammation.

    abstract:PURPOSE:The neurological molecular mechanisms underlying the voiding dysfunction associated with nonbacterial chronic prostatitis/chronic pelvic pain syndrome remain poorly understood. In this study, we assessed whether prostate inflammation activated bladder afferent neurons, leading to bladder dysfunction, and sought...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1836124.062

    authors: Park JS,Jin MH,Hong CH

    更新日期:2018-06-01 00:00:00

  • Factors affecting trial without catheter for first spontaneous acute urinary retention.

    abstract:PURPOSE:To find the association of trial without catheter (TWOC) outcome for first spontaneous acute urinary retention (AUR) in benign prostatic obstruction with age, prior lower urinary tract symptoms (LUTS), retention volume at catheterization (RV), and size of prostate. METHODS:Our prospective observational analyti...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.2013.17.3.121

    authors: Mahadik P,Vaddi SP,Godala CM,Reddy VV,Sambar VK

    更新日期:2013-09-01 00:00:00

  • Neuroprotective Effects of Bone Marrow Stromal Cell Transplantation in Combination With Treadmill Exercise Following Traumatic Brain Injury.

    abstract:PURPOSE:Traumatic brain injury (TBI) causes cognitive impairments, motor deficits, and neuropsychiatric/behavioral deficits problems. Transplantation of bone marrow stromal cells (BMSCs) facilitates functional recovery from brain insults. Treadmill exercise increases neurogenesis and inhibits apoptosis. In this study, ...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1632616.308

    authors: Shin MS,Park HK,Kim TW,Ji ES,Lee JM,Choi HS,Kim MY,Kim YP

    更新日期:2016-05-01 00:00:00

  • Electroanatomical Mapping of the Urinary Bladder.

    abstract::A noncontact mapping system (EnSite) was used for electroanatomical mapping of the bladder simultaneously with pressure flow study in three women with lower urinary tract symptoms. We selected the periods of obvious detrusor activity. Data were processed to remove baseline drift, and an envelope of electrovesicography...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1630504.252

    authors: Farag F,Koens M,Tijssen M,Jong Sd,Fabius T,Tromp J,Breda Hv,Smeets J,Feitz W,Heesakkers J

    更新日期:2016-06-01 00:00:00

  • Botulinum toxin in neurogenic detrusor overactivity.

    abstract:PURPOSE:To evaluate the effects of botulinum toxin on urodynamic parameters and quality of life in patients with neurogenic detrusor overactivity. METHODS:Thirty four adult patients with spinal cord injury and detrusor overactivity were selected. The patients received 300 units of botulinum toxin type A. The endpoints...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.2012.16.3.139

    authors: D'Ancona CA,Ferreira RS,Rassi MC

    更新日期:2012-09-01 00:00:00

  • The Efficacy of Epidural Ketamine on Shivering during Transurethral Resection of the Prostate under Epidural Anesthesia.

    abstract:PURPOSE:Ketamine may decrease core-to-peripheral redistribution of heat through direct central sympathetic stimulation and inhibition of norepinephrine uptake into postganglionic sympathetic nerve endings. The purpose of this study was to evaluate the efficacy of epidural ketamine in preventing shivering during transur...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.2010.14.2.105

    authors: Han DY,Jeong HJ,Lee C,Choi DH

    更新日期:2010-08-01 00:00:00

  • Urethral Closure Pressure at Stress: A Predictive Measure for the Diagnosis and Severity of Urinary Incontinence in Women.

    abstract:PURPOSE:Maintaining urinary continence at stress requires a competent urethral sphincter and good suburethral support. Sphincter competence is estimated by measuring the maximal urethral closure pressure at rest. We aimed to study the value of a new urodynamic measure, the urethral closure pressure at stress (s-UCP), i...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1732686.343

    authors: Pizzoferrato AC,Fauconnier A,Fritel X,Bader G,Dompeyre P

    更新日期:2017-06-01 00:00:00

  • Innovative Distribution Priorities for the Medical Devices Industry in the Fourth Industrial Revolution.

    abstract:PURPOSE:This study aimed to set priorities for improving the medical device distribution structure and to suggest an innovative improvement plan for the distribution structure using the analytic hierarchy process (AHP) method, focusing on stakeholders in the medical device industry. METHODS:This study conducted a surv...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1836152.076

    authors: Lee M,Yoon Y,Ryu GH,Bok HS,Yoon K,Park S,Lee KS

    更新日期:2018-07-01 00:00:00

  • Erratum: Tape Shortening for Recurrent Stress Urinary Incontinence After Transobturator Tape Sling: 3-Year Follow-up Results.

    abstract::[This corrects the article on p. 164 in vol. 14, PMID: 21179334.]. ...

    journal_title:International neurourology journal

    pub_type: 杂志文章,已发布勘误

    doi:10.5213/inj.2011.15.3.181

    authors:

    更新日期:2011-09-01 00:00:00

  • Clean Intermittent Self-Catheterization as a Treatment Modality for Urinary Retention: Perceptions of Urologists.

    abstract:PURPOSE:Clean intermittent self-catheterization (CISC) is now considered the gold standard for the management of urinary retention. In the literature, several articles on patients' perspectives on CISC and adherence to this technique have been published. No studies have yet explored the points of view of professional c...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1734824.412

    authors: Weynants L,Hervé F,Decalf V,Kumps C,Pieters R,Troyer B,Everaert K

    更新日期:2017-09-01 00:00:00

  • Erratum: Increased Expression of Herpes Virus-Encoded hsv1-miR-H18 and hsv2-miR-H9-5p in Cancer-Containing Prostate Tissue Compared to That in Benign Prostate Hyperplasia Tissue.

    abstract::[This corrects the article on p. 122 in vol. 20, PMID: 27377944.]. ...

    journal_title:International neurourology journal

    pub_type: 已发布勘误

    doi:10.5213/inj.1620err.002

    authors: Yun SJ,Jeong P,Kang HW,Shinn HK,Kim YH,Yan C,Choi YK,Kim D,Ryu DH,Ha YS,Kim TH,Kwon TG,Kim JM,Suh SH,Kim SK,Kim SY,Kim ST,Kim WT,Lee OJ,Moon SK,Kim NH,Kim IY,Kim J,Cha HJ,Choi YH,Cha EJ,Kim WJ

    更新日期:2016-12-01 00:00:00

  • Effect of Nerve-Sparing Radical Prostatectomy on Urinary Continence in Patients With Preoperative Erectile Dysfunction.

    abstract:PURPOSE:We aimed to assess whether nerve-sparing radical prostatectomy (nsRP) is associated with improved recovery of urinary continence compared to non-nerve-sparing radical prostatectomy (nnsRP) in patients with localized prostate cancer and preoperative erectile dysfunction. METHODS:A total of 360 patients with org...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1630428.214

    authors: Park YH,Kwon OS,Hong SH,Kim SW,Hwang TK,Lee JY

    更新日期:2016-03-01 00:00:00

  • Population-based survey on disease insight, quality of life, and health-seeking behavior associated with female urinary incontinence.

    abstract:PURPOSE:To evaluate disease insight, personal distress, and healthcare-seeking behavior of women with urinary incontinence (UI) to improve women's health in Korea. METHODS:In October 2012, 500 Korean women residing around Seoul, Incheon, and Gyeonggi-do were selected by random sampling for a population-based cross-sec...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.2015.19.1.39

    authors: Choi H,Park JY,Yeo JK,Oh MM,Moon du G,Lee JG,Bae JH

    更新日期:2015-03-01 00:00:00

  • Genetic and Epigenetic Alterations in Bladder Cancer.

    abstract::Bladder cancer is one of the most common cancers worldwide, with a high rate of recurrence and poor outcomes as a result of relapse. Bladder cancer patients require lifelong invasive monitoring and treatment, making bladder cancer one of the most expensive malignancies. Lines of evidence increasingly point to distinct...

    journal_title:International neurourology journal

    pub_type: 杂志文章,评审

    doi:10.5213/inj.1632752.376

    authors: Li HT,Duymich CE,Weisenberger DJ,Liang G

    更新日期:2016-11-01 00:00:00

  • Presynaptic Dysfunction by Familial Factors in Parkinson Disease.

    abstract::Parkinson disease (PD) is the second most prevalent neurodegenerative disorder after Alzheimer disease. The loss of specific brain area, the substantia nigra pars compacta is known as a major etiology, however it is not fully understood how this neurodegeneration is initiated and what precisely causes this disease. As...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1836216.108

    authors: Lee W,Koh S,Hwang S,Kim SH

    更新日期:2018-10-01 00:00:00

  • Aerobic exercise affects myostatin expression in aged rat skeletal muscles: a possibility of antiaging effects of aerobic exercise related with pelvic floor muscle and urethral rhabdosphincter.

    abstract:PURPOSE:Aging-induced loss of muscle mass and subsequent reduction of strength is a fundamental cause of frailty, functional decline, and disability. And this may lead to muscular dysfunction, voiding dysfunction, or urinary incontinence due to pelvic muscle weakness induced by aging. Physical exercise has been recomme...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.2014.18.2.77

    authors: Ko IG,Jeong JW,Kim YH,Jee YS,Kim SE,Kim SH,Jin JJ,Kim CJ,Chung KJ

    更新日期:2014-06-01 00:00:00

  • Long-term Outcomes of Augmentation Cystoplasty in a Pediatric Population With Refractory Bladder Dysfunction: A 12-Year Follow-up Experience at Single Center.

    abstract:PURPOSE:Augmentation cystoplasty (AC) is a surgical procedure used in adults and children with refractory bladder dysfunction, including a small bladder capacity and inadequate bladder compliance, and in whom conservative and medical treatment has failed. This study was aimed to determine the long-term outcomes of AC i...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1836174.087

    authors: Mehmood S,Alhazmi H,Al-Shayie M,Althobity A,Alshammari A,Altaweel WM,Almathami A,Vallasciani S

    更新日期:2018-12-01 00:00:00

  • Open-label, Intermittent Dose, Prospective Study Evaluating the Effects of Tadalafil on Lower Urinary Tract Symptoms and Erectile Function in Patients with Benign Prostatic Hyperplasia: Continuation and Durability of Effects.

    abstract:PURPOSE:Benign prostatic hyperplasia is often accompanied by age-related comorbidity, such as erectile dysfunction (ED). Recent data suggest an association between ED and lower urinary tract symptoms (LUTS), and increasing evidence indicates that the clinical use of phosphodiesterase type 5 (PDE5) inhibitors provides r...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.2010.14.1.7

    authors: Kim TB,Kim KH,Yoon SJ

    更新日期:2010-04-01 00:00:00

  • Socioeconomic costs of overactive bladder and stress urinary incontinence in Korea.

    abstract:PURPOSE:We quantified and described the economic burden of overactive bladder and stress urinary incontinence in Korea. We calculated direct costs by identifying public and private data sources that contain population-based data on resource utilization by patients with stress urinary incontinence and overactive bladder...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.2012.16.1.23

    authors: Sung W,You H,Yoon TY,Lee SJ

    更新日期:2012-03-01 00:00:00