Abstract:
PURPOSE:We aimed to evaluate obesity, a risk factor of metabolic syndrome, and its association with prostatic enlargement in a retrospective cohort in Korea. METHODS:Baseline data were obtained from the Korean Genome and Epidemiology Study on Atherosclerosis Risk of Rural Areas in the Korean General Population (KoGES-ARIRANG). Between March 2015 and November 2015, 2,127 male participants of KoGES-ARIRANG were invited to the Korean Prostate Health Council Screening Program, and 602 participants underwent urological examination, including serum prostate specific antigen measurement and transrectal ultrasonography, and completed the International Prostate Symptom Score questionnaire. The data for 571 participants were analyzed, after excluding 31 men who had a history of prostatic disease or testosterone replacement, or had undergone a prior prostatic surgery or procedure. RESULTS:Among components of metabolic syndrome, waist circumference had a statistically significant linear correlation with incremental increases in prostate volume (B=0.181, P=0.004). Abdominal obesity as determined by anthropometric measures including body mass index (odds ratio [OR], 1.205; 95% confidence interval [CI], 1.088-1.336), waist circumference (OR, 1.073; 95% CI, 1.032-1.115), body fat (OR, 1.126; 95% CI, 1.056-1.202), and visceral fat composition (OR, 1.667; 95% CI, 1.246-2.232) was significantly associated with the presence of high-volume benign prostatic hyperplasia (BPH) (prostate volume≥ 40 mL). Furthermore, the highest quartile of serum leptin (OR, 3.541; 95% CI, 1.103-11.365) and adiponectin levels (OR, 0.315; 95% CI, 0.102-0.971) were significantly correlated with high-volume BPH compared to the lowest quartile of levels. CONCLUSIONS:Abdominal obesity and serum leptin level are positively associated with prostate growth, whereas serum adiponectin level is inversely associated with the presence of prostatic enlargement.
journal_name
Int Neurourol Jjournal_title
International neurourology journalauthors
Jung JH,Ahn SV,Song JM,Chang SJ,Kim KJ,Kwon SW,Park SY,Koh SBdoi
10.5213/inj.1632584.292subject
Has Abstractpub_date
2016-12-01 00:00:00pages
321-328issue
4eissn
2093-4777issn
2093-6931pii
inj-1632584-292journal_volume
20pub_type
杂志文章abstract::The clinical success of mirabegron as the first β3-adrenoceptor (AR) agonist for treatment of the overactive bladder (OAB) syndrome, has resulted in substantial interest in its site and mechanism of action. Even if the adrenergic innervation of the bladder and urethra has been well studied, the location(s) of β3-ARs i...
journal_title:International neurourology journal
pub_type: 杂志文章,评审
doi:10.5213/inj.1734850.425
更新日期:2017-03-24 00:00:00
abstract:PURPOSE:This study aimed to set priorities for improving the medical device distribution structure and to suggest an innovative improvement plan for the distribution structure using the analytic hierarchy process (AHP) method, focusing on stakeholders in the medical device industry. METHODS:This study conducted a surv...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.1836152.076
更新日期:2018-07-01 00:00:00
abstract:PURPOSE:Bladder wall thickness has been reported to be associated with overactive bladder (OAB) in women. Diabetic women have an increased risk for OAB syndrome and may have an increased risk for bladder wall thickness. METHODS:A total of 235 female patients aged 40 to 75 years were categorized into four groups. The f...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2013.17.2.67
更新日期:2013-06-01 00:00:00
abstract:PURPOSE:To review the clinical outcomes of patients with voiding dysfunction who have detrusor overactivity with impaired contractility (DOIC) diagnosed with urodynamic studies. METHODS:Urodynamic reports from 2005 to 2009 were reviewed, and 54 male patients had findings consistent with DOIC. Patients with acontractil...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2014.18.3.133
更新日期:2014-09-01 00:00:00
abstract::The apical surface of mammalian urinary epithelium is covered by numerous scallop-shaped membrane plaques. This plaque consists of four different uroplakins (UPs) and integral membrane proteins. UPs, which are a member of the tetraspanin superfamily, are assembled into plaques that act as an exceptional barrier to wat...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2011.15.1.4
更新日期:2011-03-01 00:00:00
abstract:PURPOSE:We quantified and described the economic burden of overactive bladder and stress urinary incontinence in Korea. We calculated direct costs by identifying public and private data sources that contain population-based data on resource utilization by patients with stress urinary incontinence and overactive bladder...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2012.16.1.23
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:The purpose of this study was to review studies that have examined the quality of life of women with urinary incontinence. MATERIALS AND METHODS:A review was conducted that used the databases PubMED, Proquest, CINAHL, and Sciencedirect. Articles were included that were published in English between 2005 and 201...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2010.14.3.133
更新日期:2010-10-01 00:00:00
abstract:PURPOSE:To investigate the clinical factors associated with the feeling of incomplete bladder emptying in female patients with lower urinary tract symptoms (LUTS). METHODS:Records were obtained from a prospectively maintained database for 353 female patients without a history of treatment for LUTS. Patients with comor...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.1938256.128
更新日期:2020-06-01 00:00:00
abstract::Aminopyridines are potassium channel blockers that increase the excitability of nerve cells and axons; therefore, they are widely used to treat different neurological disorders. Here we present a patient with idiopathic downbeat nystagmus and lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia who ...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2014.18.4.221
更新日期:2014-12-01 00:00:00
abstract:PURPOSE:Ketamine may decrease core-to-peripheral redistribution of heat through direct central sympathetic stimulation and inhibition of norepinephrine uptake into postganglionic sympathetic nerve endings. The purpose of this study was to evaluate the efficacy of epidural ketamine in preventing shivering during transur...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2010.14.2.105
更新日期:2010-08-01 00:00:00
abstract::Bladder cancer is one of the most common cancers worldwide, with a high rate of recurrence and poor outcomes as a result of relapse. Bladder cancer patients require lifelong invasive monitoring and treatment, making bladder cancer one of the most expensive malignancies. Lines of evidence increasingly point to distinct...
journal_title:International neurourology journal
pub_type: 杂志文章,评审
doi:10.5213/inj.1632752.376
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:The purpose of this study was to assess the current management status of patients with urological issues and to examine the level of knowledge and practice behaviors regarding urinary incontinence (UI) among Korean healthcare providers in long-term care hospitals. METHODS:This study used a cross-sectional desc...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2015.19.4.259
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:To assess the urodynamic findings in patients with Parkinson disease (PD) with overactive bladder symptoms. METHODS:We performed a retrospective chart review of all PD patients who were seen in an outpatient clinic for lower urinary tract symptoms (LUTS) between 2010 and 2017 in a single-institution. Only pati...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.1938086.043
更新日期:2019-09-01 00:00:00
abstract:PURPOSE:We aimed to assess whether nerve-sparing radical prostatectomy (nsRP) is associated with improved recovery of urinary continence compared to non-nerve-sparing radical prostatectomy (nnsRP) in patients with localized prostate cancer and preoperative erectile dysfunction. METHODS:A total of 360 patients with org...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.1630428.214
更新日期:2016-03-01 00:00:00
abstract:PURPOSE:We investigated bladder function, with a special focus on nonvoiding contractions (NVCs), in awake rats with chronic chemical cystitis and bladder outlet obstruction (BOO) by use of simultaneous registrations of intravesical and intraabdominal pressures. In addition, we tested the effects of tolterodine on the ...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2011.15.3.120
更新日期:2011-09-01 00:00:00
abstract::The neurological coordination of the lower urinary tract can be analyzed from the perspective of motor neurons or sensory neurons. First, sensory nerves with receptors in the bladder and urethra transmits stimuli to the cerebral cortex through the periaqueductal gray (PAG) of the midbrain. Upon the recognition of stim...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2040318.159
更新日期:2020-09-01 00:00:00
abstract:Purpose:This study aimed to evaluate the accuracy and reliability of a new smartphone-based acoustic uroflowmetry compared to conventional uroflowmetry. Methods:This was a prospective validation study enrolling 128 subjects from September 2017 to April 2018 comparing a novel acoustic uroflowmetry to conventional urofl...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2040250.125
更新日期:2021-01-04 00:00:00
abstract:PURPOSE:Augmentation cystoplasty (AC) is a surgical procedure used in adults and children with refractory bladder dysfunction, including a small bladder capacity and inadequate bladder compliance, and in whom conservative and medical treatment has failed. This study was aimed to determine the long-term outcomes of AC i...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.1836174.087
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:As the elderly population increases, a growing number of patients have lower urinary tract symptom (LUTS)/benign prostatic hyperplasia (BPH). The aim of this study was to develop decision support formulas and nomograms for the prediction of bladder outlet obstruction (BOO) and for BOO-related surgical decision-...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.1734852.426
更新日期:2017-04-01 00:00:00
abstract:PURPOSE:To evaluate whether hydrodistention with fulguration of Hunner lesions (HD/FUL) plus maintenance dimethyl sulfoxide (DMSO) therapy prolongs the recurrence-free time in patients with Hunner type interstitial cystitis (IC). METHODS:The study enrolled patients with Hunner type IC who required repeat HD/FUL due to...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.1938110.055
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:To evaluate the effects of botulinum toxin on urodynamic parameters and quality of life in patients with neurogenic detrusor overactivity. METHODS:Thirty four adult patients with spinal cord injury and detrusor overactivity were selected. The patients received 300 units of botulinum toxin type A. The endpoints...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2012.16.3.139
更新日期:2012-09-01 00:00:00
abstract:PURPOSE:Benign prostatic hyperplasia is often accompanied by age-related comorbidity, such as erectile dysfunction (ED). Recent data suggest an association between ED and lower urinary tract symptoms (LUTS), and increasing evidence indicates that the clinical use of phosphodiesterase type 5 (PDE5) inhibitors provides r...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2010.14.1.7
更新日期:2010-04-01 00:00:00
abstract:PURPOSE:Aging-induced loss of muscle mass and subsequent reduction of strength is a fundamental cause of frailty, functional decline, and disability. And this may lead to muscular dysfunction, voiding dysfunction, or urinary incontinence due to pelvic muscle weakness induced by aging. Physical exercise has been recomme...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2014.18.2.77
更新日期:2014-06-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of an alpha-1 adrenergic receptor (α1-AR) blocker for the treatment of female voiding dysfunction (FVD) through a pressure-flow study. METHODS:This was a randomized, double-blind, placebo-controlled trial. Women aged ≥18 years with voiding symptoms, as defined by an American Urological...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.1834904.452
更新日期:2018-03-01 00:00:00
abstract:PURPOSE:Transcutaneous electrical neural stimulation (TENS), as a non-invasive modality, has been clinically used as an alternative treatment for children with overactive bladder (OAB). We conducted a pooled analysis to explore the effect of TENS on OAB. METHODS:The Preferred Reporting Items for Systematic Reviews and...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.1938232.116
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:This study reports the development of the Korean Version of the Treatment Satisfaction Visual Analogue Scale (TS-VAS) and the Overactive Bladder Satisfaction with Treatment Questionnaire (OAB-SAT-q) based on the original versions, with subsequent linguistic validation by Korean patients with overactive bladder ...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.1734992.496
更新日期:2017-12-01 00:00:00
abstract:PURPOSE:In this study, we compared the treatment outcomes for an α-blocker between 2 groups of men, one with high sympathetic activity (HSA) and another with low sympathetic activity (LSA) or normal sympathetic activity. METHODS:A total of 159 men (≥50 years of age) with lower urinary tract symptoms resulting from ben...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2015.19.2.107
更新日期:2015-06-01 00:00:00
abstract::This review assessed the epidemiology of voiding dysfunctions in South Korea. Comprehensive understanding of this epidemiology is crucial because the senior population and the social burden are increasing because of voiding dysfunctions is growing. We searched the medical records using several terms related to voiding...
journal_title:International neurourology journal
pub_type: 杂志文章,评审
doi:10.5213/inj.1630502.251
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:The aim of this study was to characterize the responsiveness of miniature excitatory postsynaptic currents (mEPSCs) to α1-adrenoceptor blockers in substantia gelatinosa (SG) neurons from the spinal cord to develop an explanation for the efficacy of α1-adrenoceptor blockers in micturition dysfunction. METHODS:M...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.1938056.028
更新日期:2019-03-01 00:00:00
abstract::[This corrects the article on p. 122 in vol. 20, PMID: 27377944.]. ...
journal_title:International neurourology journal
pub_type: 已发布勘误
doi:10.5213/inj.1620err.002
更新日期:2016-12-01 00:00:00